The bottom of your eyes makes you look haggard and tired, which not only affects the appearance of your child, but also adversely affects your personal communication. Surgery to remove bags under the eyes is a better way now, but some people are worried about hurting their eyes. So, can hyaluronic acid be used to get rid of eye bags? Let’s listen to the popular science of Hangzhou time experts. Can hyaluronic acid be used to remove eye bags? Experts said that injection of hyaluronic acid can be used to remove eye bags. Hyaluronic acid removes eye bags mainly by injecting hyaluronic acid to fill the tear groove, so as to achieve the purpose of eliminating eye bags. Early facial plastic surgery simply filled the tear groove, and the effect was not very satisfactory. It often caused the eye bags to become larger or form a stripe ridge near the tear groove. At present, the technology for injecting hyaluronic acid is more perfect, not only to fill the tear groove, but also to rebuild the “apple muscle”. The “apple muscle” is located two centimeters below the eyes and has an inverted triangular shape, also known as “smile muscle”. Hyaluronic acid eye bags are a better method, and the process is safer and more reliable. Its shortcoming is that the effect is not long-lasting. The general effect can only be maintained for about 6 months. The beauty seeker needs to be injected again to maintain the effect. Injecting hyaluronic acid to remove bags under the eyes also has the following advantages: Hyaluronic acid to remove bags under the eyes can make the beautician bid farewell to the troubles of the bags under the eye, and can be completed in a few minutes. Reduce pain. At the same time, the new injection method is adopted, so the injection effect can be seen immediately. Hyaluronic acid eye bags have been clinically validated for many years. Therefore, hyaluronic acid eye bags are safe. There is only slight swelling and pain in the whole process. There is no big pain. The beauty seekers have a high degree of acceptance. Hyaluronic acid eye bags are the most cost-effective among all eye bags, so those who seek beauty can choose with confidence. However, experts remind beauty seekers that women who are pregnant or breastfeeding, under the age of 18, locally have inflammation or infection of the skin, and those who are taking anticoagulant drugs inject this product, which causes a great risk of swelling or bleeding.
The problem of showing age varies from person to person. If you are a young lady who pays attention to your body, you will still maintain a relatively good figure as you get older. “It feels like there are decree lines on your face. Go for a hyaluronic acid filling!” My nose doesn’t seem to be firm enough, let’s call hyaluronic acid!” Hyaluronic acid has almost become a life-saving straw for Jimei. Every time the facial skin appears, I want to use hyaluronic acid to improve it.  . Last month on the 20th, there was a little fairy who experienced hyaluronic acid filling. Let’s Kang Kang her effect together~ The following is her readme! Before treatment, the doctor scored me to assess the overall facial condition, pointed out the defects on my face, the tear groove was obvious, the apple muscle was not full enough, and some relaxation. According to my situation, Professor Li Yuanhong suggested that I do hyaluronic acid to fill the tear groove +Feng apple muscle. The detailed treatment plan is very reassuring. After communication, I started to prepare for injection. The nurse does a good job of facial cleansing and disinfection, taking care of every detail professionally. I never had an injection before and thought it would hurt. As a result, the operation was finished after a while. The procedure was very easy and I felt almost nothing. Let me show you the photos just after the injection. I can see some effects~ There are some improvements after the completion of the injection, but they are not particularly obvious. The natural ones quietly become younger and more beautiful. If you want to fill hyaluronic acid for better results, you can refer to the doctor’s advice.  . Q&.AQ about hyaluronic acid filling: Can hyaluronic acid filled with water-light injection be filled? Can’t. The medical name of hyaluronic acid is called hyaluronic acid. Hyaluronic acid exists in the dermis layer of human skin. It plays an important role in the matrix. It has strong water absorption capacity, is responsible for storing water, increasing skin elasticity, and its stability is compatible with the human body. Better, so it is a safe and natural skin filling material. The macromolecule hyaluronic acid has a high degree of cross-linking, the product is “hard”, and has good plasticity and support. Shuiguang needle, its main component is hyaluronic acid, the difference is that Shuiguang needle can add many other ingredients, so as to achieve different cosmetic purposes. The hyaluronic acid used for the water polish needle has a low degree of cross-linking, and the hardness and viscosity are small, and the plasticity and supporting force are also small.  .Q: How long does the filling treatment take? The filling site is different, and the time is also different. Generally, if you fill 1-2 hyaluronic acid in the tear groove, it will take about 1 hour if you add the diagnosis, evaluation, anesthesia, disinfection, and ice compress. Q: What are the precautions after filling with hyaluronic acid? Avoid water at the local needle eye for 6-8 hours, avoid massage and kneading within one week to avoid deformation and displacement, avoid hot compress, hot spring, steam sauna to accelerate the metabolism of hyaluronic acid, and avoid radio frequency treatment at the filling site within 3 months. Q: Will the face become stiff with hyaluronic acid injection? Strictly speaking, the continuous injection of hyaluronic acid will not cause stiffness in the face. Because after injection of hyaluronic acid, hyaluronic acid will be gradually absorbed by the body over time, combined with its own cells to promote the growth of collagen. After the hyaluronic acid is completely absorbed, the collagen will also decrease, and the skin will return to the state where the hyaluronic acid was not injected. At this time, re-inject the hyaluronic acid. In fact, it is the same as the first injection of hyaluronic acid. It will not be because of multiple injections. And the face is stiff. In this case, why do many people have facial stiffness? In fact, there are only two reasons: 1. Over-injection of hyaluronic acid is limited. It is not that the more hyaluronic acid is injected, the better. Everyone’s situation is different. Some people may only need one, while others It needs a lot of support. Others will be eager to achieve success, even if they are not suitable, they still require the doctor to give a lot of hyaluronic acid, too much injection or too much area, resulting in a stiff face and unnatural expression. 2. Improper injection location When the injection location is improper, it may also cause facial stiffness, because our facial capillaries and nerves are abundant. If the injection location is improper, it is easy to have problems.  . Who can escape time and gravity? So, if you have only one hyaluronic acid no matter what age, you may wish to try to adjust the injection of these parts to improve the proportion of the face and make yourself look more three-dimensional and exquisite!  .
Water is a very important natural resource for us. One of the important reasons why the earth is the only living planet in the solar system is that there is water. 71% of the earth’s area is ocean. The human body can actually be said to be composed of water, and the water content in the body accounts for about 70%, so if the body lacks water, it may cause harm to the body. Which diseases are related to drinking less water? 1. Urinary calculi The raw urine of the human body will contain calcium, oxalic acid, uric acid and other substances. It is clear to those who have studied chemistry. The combination of calcium and oxalic acid will generate calcium oxalate crystals. However, when the body is normal or drinking plenty of water, urine production will increase. On the one hand, urine dilution is not conducive to the combination of oxalic acid and calcium to form calcium oxalate. Therefore, it is not easy to form stones. If you drink too little water, your urine is too little, and the concentration of calcium and oxalic acid in your urine is too high to reach a supersaturated state, it will promote the formation of stones. 2. Thrombotic disease The formation of thrombus is closely related to the increase in blood viscosity. The blood contains components such as lipids and platelets. The more diluted the blood, the faster the flow in the blood vessel, and the less these components settle in the blood vessel wall. But the opposite is more, and thrombosis gradually formed. Drinking less water will reduce the blood volume. Due to the concentration of blood, the concentration of platelets and lipids will increase accordingly, which will accelerate the deposition of these components and attach to the blood vessel wall to form thrombosis, which leads to diseases such as cerebral infarction or myocardial infarction. 3. After the constipation is absorbed, the food debris forms feces and can pass through the intestine smoothly and be excreted from the body. It is inseparable from the softening and lubrication of intestinal juice and water in the intestine. If you drink less water, the secretion of intestinal fluid and water in the intestine will also be reduced, and the dehydration of the stool will appear dry and dry, which will lead to obstruction of discharge and cause constipation. 4. The pathological basis of gout gout is high uric acid. One of the important measures to promote uric acid excretion is to drink plenty of water. If the water is not drunk too much, the excessive uric acid in the body cannot be excreted through urine in time, which will cause uric acid to deposit in the joints to form urine The salt crystals eventually form gout stones and even induce gout attacks. 5. Malignant tumors have been found by comparison. The appearance of tumor cells is related to the changes in the water characteristics of normal cells. One of the important causes of cancer is the result of long-term accumulation of toxic substances in the body inside and outside the cells, which results in cell damage. In the case of drinking more water, these toxic substances can be excreted in time to reduce the accumulation, so some scientists suggest that drinking more water has a certain role in preventing cancer. “Dietary Guidelines for Chinese Residents 2016” recommends: In addition to metabolism and food, normal adults should drink at least 1500-1700ml of water per day. If they are calculated according to ordinary 200-250ml cups, they should drink 7-8 glasses of water per day. . It is always beneficial to drink as much water as the body can tolerate. References: “Chinese Resident’s Meal Guide 2016” (part of the picture source network in the text, the copyright belongs to the original author, thank you for the picture author, if you find any violation of your copyright, please contact me, I will delete .)
Everyone knows that the most common disease in the urinary system is called “kidney stones”. What is the composition of kidney stones? What are their types according to the ingredients? What are their characteristics? Is it like the pebbles we saw by the river? Then I will give you a simple science-the composition and classification of kidney stones. 1. The composition of kidney stones is caused by the abnormal accumulation of crystalline substances (such as calcium, oxalic acid, uric acid, cystine, etc.) in the kidneys. 90% contains calcium, of which calcium oxalate stones are the most common. (Expanded knowledge: The main chemical composition of the pebbles we see on the river bed in our lives is silica, and ordinary stones are generally composed of calcium carbonate and silica). Second, the classification of stones (1) calcium oxalate stones . calcium oxalate Stones are the most common in daily life, accounting for 71% to 84%. Urine is acidic. The characteristics of such stones are hard, unbreakable, rough, irregular, tan, easy to damage the tissue and cause hematuria. The X-ray is characterized by deep markings in the stones, irregular edges, and sometimes a kidney pelvis or calyx shape. (2) Calcium phosphate stones . Urine is alkaline, characterized by brittle, rough, irregular, off-white, yellow or brown, often caused by urinary tract infection and obstruction. Mixed with calcium oxalate or magnesium ammonium phosphate to form stone. The X-rays are clear and the striae are more obvious. When filling the entire renal pelvis and calyces, they are staghorn. (3) Uric acid stones . Urine is continuously acidic, characterized by hard, smooth, granular, yellow or brownish red, and abnormal uric acid metabolism. Most are composed of a single uric acid, and the development under the X-ray is lighter or not developed. (4) Magnesium ammonium phosphate stones . belong to infectious stones, characterized by smooth, polyhedral or vertebral body, which increases rapidly, mostly related to repeated urinary tract infection and abnormal anatomy of urinary tract. X-ray development is clear, and the density of stones is uneven. (5) Cystine stones are rare genetic diseases. 82% of patients with cystinuria have cystine stones, and 35% occur in infants or children. It is characterized by soft, smooth, waxy, light yellow to yellow brown, and its crystal is hexagonal. It is easy to develop on X-ray film due to sulfur content.
Everyone who grows upside down must have a full face. Some people are obviously less than 30+, but the impression is very old. why? In fact, it is all caused by facial depression. The appearance of facial depression: tear grooves, temples, apple muscles, decrees…the facial depression and skin relaxation and wrinkles are also called the three major signs of aging. Not only does it seem to have no affinity, but it is also older than its peers. What to do if the face is sunken? The appearance of depressions on the face is a trace of years, and can be restored to a young state through facial filling; there are two common methods of facial filling: one is hyaluronic acid injection filling, and the other is autologous fat filling; the former is convenient for injection, the effect is excellent, and the latter is taken Slimming, using beauty, turning fat into treasure. Which one should I choose? The ladies of beauty are tangled. Let the editor answer your doubts from a professional perspective! 01 Hyaluronic acid Hyaluronic acid is a linear polymer polysaccharide composed of disaccharide units. It exists in the connective tissues and dermis of the human body. It is a naturally occurring substance in tissues and is also a transparent colloidal substance. The earliest hyaluronic acid was used as a viscoelastic agent for ophthalmic intraocular lens implantation surgery, as a filler for joint surgery such as osteoarthritis and rheumatoid arthritis, and can also be used to prevent postoperative adhesion and promote the healing of skin wounds. 02 Autologous fat Autologous fat is the fat meat that you dislike most. The magical self-fat filling is to move the fat on your body (such as the fat in the waist and abdomen and thighs) to another place, so that it will show the combined effect of slim waist and buttocks and thin legs and big breasts. What are the differences between them? 01 The hyaluronic acid filling area can remove static wrinkles (mouth corner lines, decree lines, etc.), and can also fill in facial depressions (forehead, temples, tear grooves, apple muscles, cheeks), and decorate the face (full lips, rhinoplasty, chin, feng Earlobe, etc.). Autologous fat can fill facial depressions (forehead, temples, tear grooves, apple muscles, cheeks), decorate the face (lip augmentation, rhinoplasty, chin augmentation) and reshape the body (breast augmentation, hip augmentation, artificial muscles), etc. 02 Filling effect Both are similar in filling effect, but in terms of shaping, such as rhinoplasty, the stiffness of autologous fat is not as good as hyaluronic acid, and in terms of overall improvement, autologous fat filling is better. Since autologous fat filling is to extract excess fat and place it in need of supplementation, such as filling the tear groove with the meat at the mouth, it can solve multiple facial problems, such as depression, wrinkles, loose contours, etc. at the same time. Hyaluronic acid only has an effect on the injection site. If you need a big face change, you should inject a lot and cooperate with thin face and other items. That is to say, in most cases, autologous fat is suitable for plump face, and hyaluronic acid is good at plump part. 03 Maintenance time The maintenance time of hyaluronic acid is related to the molecular weight of the injection selected by itself, and to the self-absorption of the beauty seeker. The maintenance time ranges from 6 to 12 months. If you want to maintain the effect for a long time, you can continue to make up. Autologous fat filling is generally long-lasting after 2-3 fillings, but autologous fat transplant filling involves not only the late absorption rate, but also the level of early survival rate, so it is very important to choose a doctor. 04 Recovery period Hyaluronic acid injection does not require a recovery period, and it immediately shows no swelling. So it is highly recommended for girls who are going to take a photo or interview tomorrow or see their in-laws the day after tomorrow~. The time for the autologous fat filling to reach the final effect is three months, and the swelling period should be spent about 10 days, which is more suitable for the potmates with sufficient time. 05 trauma risk Hyaluronic acid confirms physical health and no contraindications for treatment before surgery, you can prepare for treatment, just apply a topical anesthetic cream to the treatment site, and treatment can be started after 20-30 minutes. The injection time is about 10-20 minutes. It is a direct injection without any trauma and no pain after surgery. Autologous fat filling requires the extraction of fat from itself, centrifugation, purification and refining, and injection into the face. The location of fat extraction has a wound, and there will be pain when recovering. 06 Technical requirements Hyaluronic acid requires professional injection, convenient and fast. If the treatment result is not satisfactory, it can also be ablated by hyaluronic acid dissolving enzyme. Autologous fat filling has higher requirements for doctors’ technology and environment, and has a large technical content. It has more links than hyaluronic acid injection. Liposuction, purification, and injection have strict and professional operating specifications. So, how should we choose? 1. People with slight depressions and relatively tight skin are generally younger beauties, only because the middle of the face or the husband and wife palace are slightly depressed, but the skin
In May 2020, the American College of Rheumatology (ACR) released the latest gout management guidelines. Compared with the 2012 ACR gout management guidelines and the 2016 European Anti-rheumatic Disease Union (EULAR) gout management guidelines, the guide has many highlights and updates . Through learning and combining with Chinese reality, we will make the following interpretations on the characteristics of the guide and its applicability to the Chinese population. Highlights and updates add conditional recommendations, emphasizing patient’s wishes. In general, the guide adds “conditional recommendations”, emphasizing that the formulation of diagnosis and treatment plans needs to be combined with patient’s wishes, and the recommendation of drugs also takes into account treatment costs. 1. It is recommended to use prophylactic drugs for 3 to 6 months of initial uric acid lowering therapy, which is shorter than the 6-month preventive medication period of the 2012 ACR gout management guidelines and the 2016 EULAR gout management guidelines. 2. The guide recommends a uric acid control target of <.360μmol/L, and no longer proposes a target of uric acid <.300μmol/L for patients with gout stone, chronic gouty arthritis and frequent attacks of gout. 3. Allopurinol is recommended as the first-line medication, including patients with moderate to severe renal impairment (CKD≥3); conditional recommendation is to replace with another xanthine oxidase inhibitor for patients with blood uric acid that does not meet the standard. Uric acid excretion drug. Febuxostat is no longer the first-line recommended medication. 4. The 2020 ACR guidelines conditionally do not recommend 24h uric acid testing and alkaline urine treatment. 5. The guide for the first time proposed the adjuvant therapeutic effect of local ice compress. 6. For the first time, it is not recommended to take vitamin C. Applicability in the Chinese population The ACR guidelines are not entirely suitable for Chinese clinical practice. 1. Is allopurinol the only first-line medication in the Chinese population? Caucasians have a relatively low risk of allopurinol hypersensitivity syndrome. A European study showed that the incidence of white allopurinol hypersensitivity syndrome was 3.19 per 100,000 person-years . However, unlike Caucasians, the Asian population has a significantly increased risk of allopurinol hypersensitivity syndrome. In a study in Taiwan, the annual incidence of allopurinol hypersensitivity syndrome in the Asian population was 4.68/ 1,000 new users . This difference is mainly due to the higher positive rate of HLA-B5801 gene in Asian population (Han: 7.4%. Caucasian: 0.7%) . Therefore, the use of allopurinol in the Asian population requires the HLA-B5801 gene test; but the gene is not available in all medical institutions. Even if it can be tested, its cost-effectiveness ratio will also affect the doctors and patients’ decisions. Therefore, considering the risk of allopurinol allergic reaction, its use in China is restricted. 2. The application of benzbromarone in Chinese population Benbenbromarone is currently the only uric acid excretion drug marketed in China, but among whites, benzbromarone can cause fulminant liver necrosis, so it has never been in the United States Listed and delisted from many European countries. Unlike Caucasians, the risk of fulminant hepatic necrosis caused by benzbromarone is rarely reported in Asian populations, and it has a good uric acid-lowering effect in Asian populations including eGFR20~60mL/min/1.73m2 Security [4-6]. Therefore, in the domestic gout guidelines, benzbromarone is still the first-line recommended drug . In the etiology of hyperuricemia, we found that about 50% of patients have decreased renal uric acid excretion (FEUA<.5.5%, UUE≤3.57mmol/d/1.73m2) (unpublished data in this group). Among patients, uric acid excretion drugs may have better efficacy; and because Asians are at risk of allopurinol hypersensitivity, so at present, benzbromarone is still the first-line drug and the most prescribed urate-lowering drug . 3. Febuxostat cardiovascular safety issues The relatively high price of febuxostat and its possible cardiovascular adverse events have led to the 2020 ACR guidelines no longer recommending it as first-line medication. A multi-center, double-blind, non-inferiority CAREs study included 6190 patients with gout with cardiovascular disease. The study showed that compared with allopurinol, the risk of cardiovascular-related death and all-cause death in the febuxostat group were both Increase . In two other observational studies, compared with allopurinol, one did not find a significant increase in the risk of febuxostat cardiovascular events and all-cause death
. 1. What is gout? Gout is a disorder of purine metabolism caused by inherited or acquired etiology, increased blood uric acid accompanied by tissue damage. The prerequisite for its onset is hyperuricemia. Gout II. What is the path of gout formation? 1 Asymptomatic hyperuricemia 80% of hyperuricemia can be asymptomatic for life. In addition to elevated serum urate concentration, there is no clinical manifestation of gout such as joint symptoms, gout stones, uric acid kidney stones. Although most patients with hyperuricemia can be asymptomatic for life, the trend towards acute gout increases with increasing serum urate concentration. Therefore, patients with asymptomatic hyperuricemia need to monitor the uric acid level, and need to see a doctor in time when the corresponding clinical manifestations appear. 2 Symptomatic clinical gout A small proportion of patients with hyperuricemia may develop clinical gout. It can be expressed as: (1) Acute gouty arthritis: the patient’s toes, ankles, knees, wrists, finger joints, elbows, etc. appear red, swollen and hot, and even joint dysfunction. (2) Gout intermittent period: between two gout attacks, ranging from several weeks to several decades. (3) Chronic gout. Stone gout: The onset joints will appear swollen, stiff, and deformed. Like stones, they are asymmetrical and have different sizes. Gout three, why is hyperuricemia formed? Hyperuricemia is the main pathogenesis of gout. The causes of hyperuricemia include excessive uric acid production, reduced excretion, or both. 1Uric acid produces too much uric acid in the human body has two sources: one is exogenous: derived from high purine foods, including animals, beans, seafood, and the purine in these foods is almost converted into uric acid after being absorbed by the body , Limiting the intake of high-purine foods can reduce the level of uric acid to a certain extent; The second is endogenous: synthesized by the body itself, accounting for about 80% of the source of uric acid in the body, that is, from the decomposition of nucleotides or nuclear proteins in the body, Foods with high calories are broken down into nucleotides and nucleoprotein content is naturally high. The formation of hyperuricemia in most patients is directly related to excessive uric acid production. No wonder doctors recommend gout patients to pay attention to a low-purine, low-calorie diet. 2 Less excretion of uric acid Excretion of uric acid is 66% excreted by the kidneys, 34% is excreted by the intestine, and other means such as perspiration do not participate in the process of uric acid excretion. Patients with renal dysfunction or long-term constipation may be caused by poor excretion Increased uric acid. 4. How does hyperuricemia cause arthritis and gout stones? urate deposits on the joints can cause reactive arthritis and redness, swelling, heat, and pain in the joints. Long-term hyperuricemia can increase the deposition of uric acid in the joints. When the urate pool is enlarged, urate crystals are deposited in cartilage, synovium, tendons, soft tissues and other places, and gout stones are formed. 5. Will the gout stone disappear? Control hyperuricemia (up to 350umol/L), and maintain this state for a certain period of time, so that gout stones can slowly disappear. The reason is that when the blood uric acid is lower than the joint cavity, urea can be reabsorbed into the blood and the gout stones gradually become smaller. However, this process may take a long time and requires patience and confidence. 6. How to treat gout patients? 1 For the treatment of gouty arthritis, the acute stage of gout attacks, anti-inflammatory and analgesia are the most important. 2 In addition to taking medicine, you should control the intake of high-purine foods and limit the intake of high-calorie foods, thereby reducing endogenous purines, drink more Water promotes the discharge of uric acid. 3 Alkalizes the body’s peracid system. 7. How should gout patients control their diet? The intake of the following foods should be restricted: (1) Animal gut and meat: In addition to the substrate purine rich in uric acid synthesis, animal gut and meat are also rich in saturated fatty acids, which are positively correlated with insulin resistance and can be reduced Renal uric acid excretion. Including chicken, duck, goose, gravy, broth, etc. (2) Seafood: high purine content in seafood can lead to increased blood uric acid levels and increased risk of developing gout in the long term, such as fish, shrimp, crab Etc. (3) Alcohol: an important dietary risk factor for gout, the risk of gout and the intake of alcohol are dose-dependently increased, especially beer. (4) sugary drinks, juices: research has found blood The uric acid level and the prevalence of hyperuricemia increase with the intake of sugar-sweetened beverages. (5) Some vegetables: all beans, cashew nuts, lotus seeds, chestnut, nori, asparagus, mushrooms, string beans, etc.
I think lying silkworm is a very delicate existence. This is said to be something that 98% of straight men do not know, but most straight men and women possess it. Why is lying silkworm a “star standard”? Just type “reclining silkworm” on Baidu and you can get a lot of comparison photos of the celebrities with and without lying silkworm.  . Apart from the superb PS technology, it is easy to see in these comparisons. It doesn’t look like a lying silkworm. It seems to be a lot more “powerful”. For women, the gentle and lovely feeling is obviously weakened. Even on the male face, when there is no lying silkworm, that kind of “boyishness” will disappear. After losing the lying silkworm, his eyes seemed to be smaller.  . . So, to sum up, the subtle effect of lying silkworms on the value of the face mainly comes from: making the eyes more three-dimensional and having the effect of enlarging the eyes. The eyes of lying silkworms are more vivid. The so-called “eyes of laughter” are usually the eyes of lying silkworms. Lying silkworms make people look gentle and lovely, and have the effect of reducing age.  .NO1. What is lying silkworm? Many little babies can’t tell whether lying silkworms or bags under the eyes, but it is still necessary to distinguish them, as long as you look at this animation, you can probably understand.  .No2. Do you need lying silkworm? I have talked about it many times. There are many beautiful facial features. Whether it suits you or not needs to be considered in all aspects. For example: what you look like; how you like it; your temperament, aura, etc. Take a star we are familiar with as an example, her lying silkworm is not obvious, and she did not deliberately emphasize it in her makeup. Because her eyelids are slightly swollen, if you deliberately strengthen the lying silkworm, there will be a feeling of swelling. Moreover, the gentle feeling brought by lying silkworm is not in line with her “not easy to provoke” people, so we see that her makeup is actually weakening lying silkworm.  .NO3. Generally speaking, you can try to shape the lying silkworm in the following situations. 1. The girl with small eyes wants to enlarge her eyes properly and bless the feeling of being young and lovely. The lying silkworm can enlarge the area occupied by the eyes on the face, and it seems that the eyes become larger. 2. Pursue girlishness and affinity, like “smiley eyes”. The expression is more abundant, the character is more lively. 3. .Narrow eye distance, eye shape is more charming, looks a little “smart” people, if you want to weaken this “powerful” feeling, lying silkworm can play a very interesting role. Have you found that when lying silkworms appear, the whole person becomes more friendly and more girlish. For girls with wider eye distances and rounder eye shapes, it seems that there is not that much difference. Perhaps it is because the wide eye distance itself is relatively mild and young.  .NO4. What kind of lying silkworm is good-looking? Finally, this problem, let us look at a picture. Do you think it is not natural? ? ? Let me summarize, the beautiful lying silkworm is very “spiritual”. Because it changes as your expression changes. When not smiling, the slight lying silkworm became obvious when smiling. And whether it is static or dynamic, it is natural and just right.  .NO5. Finally, let’s talk about the “acquisition” method of lying silkworms. The first is the simplest, draw a lying silkworm out. How to draw a lying silkworm? If you are born with a silkworm, please stand by. If you don’t have a silkworm, please accept the following benefits. Whether you want to wear glasses and have a high face value, or want to make yourself age-reduced during daily makeup, this simple lying silkworm makeup is a good way. ◆Select eyeshadow with brightening function and brush under the eyes. ◆ Use dark eye shadow to swipe along the bottom edge of the silkworm that was just brightened (the texture is better with a matte surface to make the shadow appear more natural). ◆ Use the eyeshadow brush to smudge the shadow area, be careful not to sweep too hard into dark circles. a little complicated? Then look at this animated picture, and you won’t be able to fill it up again!  . The second method of hyaluronic acid filling, hyaluronic acid filling, macromolecule hyaluronic acid has better shape, is the first choice for injection lying silkworm recommended by doctors at home and abroad. Injecting hyaluronic acid to fill the lying silkworm, comprehensively considering the injection according to the individual’s eye condition, facial features and eye condition, the appropriate amount of hyaluronic acid is slowly and evenly injected under the eye to fill the lying silkworm to achieve immediate eye tightening The effect of the skin and plump lying silkworm makes our eyes three-dimensional, deep and cute immediately~ Above, do you know the questions about lying silkworms? Do you want to try
1. The air conditioner is not always open on hot summer days. Everyone likes to stay in a cool air-conditioned house, but many people do not know that it is easy to breed bacteria and microorganisms in the environment where the air conditioner is turned on for a long time. For those with weak resistance, It is easy to cause various diseases. Such as throat, tonsil inflammation (streptococcal infection), etc., need immediate treatment, and antibiotics should be taken thoroughly, not halfway (by the doctor), otherwise streptococcus is susceptible to kidney disease, especially for children. But in the process of using antibiotics, we must pay attention to the appropriate amount and appropriate to avoid antibiotic poisoning. 2. Overeating Nowadays, more and more people like to have dinner together. They often eat too much big fish and meat and seafood without restraint. Some people ask, how can you eat kidney disease? Seafood is high-purine food, uric acid is the end product of purine metabolism, disorder of purine metabolism or reduced excretion of uric acid by the kidneys can increase blood uric acid. When the concentration of urate in the blood is supersaturated, urate precipitation crystals can be deposited in the kidneys, causing renal parenchymal damage. This is “uric acid kidney neck, also known as “hyperuricemia kidney neck. And eat Potato chips, instant noodles, etc., can make people unknowingly absorb excessive salt, leading to increased blood pressure, which can lead to kidney disease. As for soft drinks and sports drinks, they are generally highly acidic. The pH of the body changes significantly after drinking. Increased probability of damage due to increased burden. 3. The most direct injury to the kidneys caused by high temperature is the high temperature in midsummer, and high temperature has direct damage to the kidneys of the human body, which can lead to dehydration of the human body and low urine output, resulting in increased kidney load and loss of water and salt metabolism in the body. , Affecting normal physiological functions, causing abdominal pain, nausea, vomiting and other symptoms. The best way to protect the kidneys in summer is to drink a small amount of cold boiled water many times to promote normal metabolism and protect kidney health. 4. How to replenish water? Kidney is the main place for excretion of metabolic wastes and medicines. Summer heat is prone to sweating a lot, so the water lost through the skin every day greatly increases, up to more than 1000 ml. Urine is concentrated when there is a lack of water, and the concentration of these substances in the urine is significantly increased, which is easy to cause kidney damage. If water is not added in time, it is easy to cause water shortage and kidney damage. Therefore, some kidney patients should pay special attention to supplement water. For the elderly, they often have no obvious thirst when the water is obviously lacking. When the weather is hot, the elderly have decreased appetite and increased sweating. In addition, the kidneys have poor water retention capacity and often have no thirst when they lack water. It is easy to cause severe water shortage and lead to damage to kidney function. The elderly must develop the habit of drinking water in moderation without being thirsty. Proper drinking before bed also helps prevent plasma concentration and thrombosis. The elderly have reduced kidney concentration and more urine at night, so they should drink water before going to bed. So how much water should each person replenish each day? This varies from person to person. The general principle is to maintain 24-hour urine output at 2000-3000 ml. We should pay attention to drinking water reasonably and develop the habit of drinking water daily. The best time to drink water is between meals and in the evening and early morning, but avoid drinking large amounts of water within half an hour before meals and immediately after eating to avoid diluting stomach acid, affecting appetite and digestion. As for what kind of water is best to drink, don’t pay too much attention, ordinary drinking water will do. 5. Periodic inspection is very important. Lastly, it is mentioned that kidney function tests are often done. It is best to stipulate that you must do routine urine screening and blood pressure tests every six months. Almost half of kidney patients undergo kidney damage unknowingly, so when the body feels unwell, it may be the end of kidney disease (uremia)-it is time to rely on the dialysis machine to survive. Summer is a splendid and beautiful season, don’t let the disease take advantage of bad habits. The kidney is very important for a person. The normal operation of the kidney function ensures the stability of the environment in the body and allows the metabolism to proceed normally. We can protect it so that it can better solve problems for us. Finally, I wish all my friends good health and stay away from disease!
. . . Westerners have straight noses and beautiful noses because their noses have thin skin and adequate cartilage support. On the contrary, Orientals’ noses are not strong enough. Our cartilage support itself is insufficient, plus thick Thick nose skin makes our nose look bloated. So our nose tip needs strong support to make our nose look good.  . . . . Regarding the choice of material for the tip of the nose pad, many beauty seekers have such questions: prosthesis, hyaluronic acid, and autologous fat can all rhinoplasty, why is it strongly recommended to use the nose tip of the autologous cartilage pad?  . .  . . Prosthesis, hyaluronic acid, and fat are not suitable for cushioning the tip of the nose!  . . . .1. There are two types of silicone and bulking in the prosthesis. In fact, these two types are not suitable for cushioning the tip of the nose. Although silicone is flexible and easy to sculpt, the silicone prosthesis has been used as an “L” shape to cushion the tip of the nose. Under the action of skin tension and gravity for a long time, the silicone prosthesis easily penetrates the skin and is exposed. Expanded material cushion The tip of the nose, if it can’t keep the nose clean and hygienic after operation, it is easy to cause retrograde infection.  . . . . 2. Hyaluronic acid as a filling material is generally suitable for the nasal tip with good bone support structure. If the general nasal tip is severely flattened, the effect of the hyaluronic acid cushion on the nasal tip is obviously not good. Moreover, excessive injection at one time can easily cause vascular embolism, leading to necrosis of skin tissue.  . . . . 3. Autologous fat is the same as hyaluronic acid, and it only has an effect on the nasal tip with good basic conditions, but there is a certain absorption rate after autologous fat injection. It may require 2 or even 3 fillings to achieve effect.  . . . . Why is autologous cartilage most suitable for cushioning the tip of the nose?  . . . .1, the support of autologous cartilage is very strong . . . . autologous cartilage has a certain flexibility, and the support is also very strong, if you use autologous cartilage to cushion the tip of the nose, especially for the kind The tip of the nose is severely flattened, and the autologous cartilage can support it well, and it will not transmit light like the silicone prosthesis.  . . . .2, the safety of the nose tip of the autologous cartilage cushion is guaranteed . . . . The nose bridge is not easy to move, but the nose tip has a lot of movement space, and the nose tip is implanted with autologous cartilage. The cartilage can establish a perfect blood relationship with its own nasal tissues and blend into one body. After several years, the tip of the nose is still the same delicate and delicate.  . . . . For different nasal tips, the material of autologous cartilage will be different: for example, if the nasal tip is good, you can choose nasal septal cartilage or ear cartilage to make the nasal tip. If the nasal tip foundation is poor, you can choose the nasal septal cartilage + Ear cartilage is used to cushion the tip of the nose. If the support between the nose itself is poor, you can choose the costal cartilage as the tip of the nose.  . . . . For more information about “rhinoplasty”, you can ask me questions.
Today, the outpatient clinic received another gout stone patient, who was just 40 years old and had been suffering from gouty arthritis for more than 20 years. More than 20 years ago, because of sudden swelling and pain in the joints, he went to the local hospital for examination and consultation. After checking the high uric acid, the doctor is very professional: Diagnosing his problem is acute gout caused by “gout arthritis”, given related anti-inflammatory and analgesic drugs for treatment, relieve pain, and eliminate local redness, but today, go to the hospital The treatment was due to “foot gout rupture”! Chalky gray fluid was flowing from the joint! What is the chalk-like liquid? The chalk gray-like liquid is what we call gout stone. The first occurrence of gout stone is yellow-white neoplasm, medium hardness, irregular, generally no obvious tenderness and fluctuation, large like walnut, small like green beans. As the disease progresses and the course of the disease prolongs, gout stones gradually increase in number and increase, and spread around multiple joints. For long-term gout stones, the surface skin can change from yellowish white to brownish yellow or brown, and the texture can also become harder, showing severe pain. Acidic urate crystals exist in gout nodules, which chemically stimulate and erode the skin tissue for a long time, so that the complete structure of the skin is destroyed, and the skin’s elasticity and tolerance are reduced and it is easy to break. In addition, as the urate crystals gradually accumulate and increase, the volume increases, the internal pressure increases, and the skin around the stones gradually thins, causing rupture. The case originated from the first manifestation of mild gout stone clinical manifestation of gout stone in the gout stone specimen hall of West Gout Rheumatism Hospital, which is a yellow-white neoplasm. .①The gout stone is stable in size and grows slowly, involving a single joint; Abnormal points;  . ③ no invasive mass or connective tissue destruction;  . ④ no severe chronic gouty joint inflammation. Medium hardness, irregular, generally no obvious tenderness and undulation, large like walnuts, small like green beans. Mild gout stone manifests moderate gout stone clinical manifestation gout stone is stable in size, slow growth involves 2-4 joints. Moderate gout stone performance Severe gout stone clinical manifestation ① Gout stone involved more than 4 joints or joints with abnormal secretions;  . ② aggressive mass or connective tissue destruction;  . ③ higher risk of infection;  . ④ Gout stone is unstable and grows rapidly; . ⑤Severe chronic gout stone joint inflammation. Severe gout stones are prone to ulceration. If the gout stones fail to be treated in time, the wound will be difficult to heal, and bacterial infections will follow. Mild gout stone ulcer: shallow wound on the surface, small area, no obvious odor of secretions. Generally, mild gout ulcers can be cured by the following treatment methods. You can use iodophor solution to disinfect the wound, then use hydrogen peroxide to clean the wound, and finally rinse it thoroughly with normal saline to remove necrotic tissue and uric acid stones as much as possible. Moderate gout stone ulcers: generally the wounds are deeper and there are more secretions from the wounds, but there is no damage to the bone tissue and no abscesses. When treating wounds, use sterile cotton balls dipped in physiological saline to scrub the ulcer, and then clean the necrotic tissue. If necessary, you may need to trim the wound surface, squeeze the gout and necrotic tissue, and then rinse with normal saline. Severe gout stone ulcers: deep wounds, abscesses, damaged bone tissue. If infected, a large amount of secretions and dead bones will appear at the wound. At this time, it is necessary to strengthen anti-infection and debridement treatment. Severe gout stones accumulate multiple joints and cause serious damage to joints and tissues. Different treatment methods for gout stones? Long-term goal of gout: The early treatment of uric acid lowering gout is mainly uric acid lowering treatment, blood uric acid level (no gout stone <360μmol/L, gout stone <300μmol/L), only effective control of the uric acid value can prevent gout The brutal growth of stone. Gout stone stage treatment is divided into surgical treatment and non-surgical treatment gout stone will affect all parts of the body, the appearance of different sizes, different parts, different sizes of gout stone treatment methods are different, but in general, the treatment method is nothing more than non-surgery Treatment and surgery. 1. Non-surgical treatment of gout is a characteristic change of gout. Long-term adherence to "standardized treatment of gout" and control of blood uric acid to less than 300μmol/L, and long-term maintenance, gout can be reduced.
With the passage of time, the collagen on the face is lost, and the crow’s feet will slowly climb to the corners of the eyes. In the clinical practice of removing crow’s feet, crow’s feet refers to the wrinkles that appear between the corners of human eyes and temples. The lines are very similar to the lines on the tails of fishes, so it is called the crow’s feet. The formation of crow’s feet is due to decreased neuroendocrine function, decreased protein synthesis rate, decreased or lost fibrocyte activity of the dermis layer, decreased or broken collagen fibers, resulting in decreased skin elasticity, increased wrinkles in the corners of the eyes, and sun exposure, dryness, coldness, and face washing Excessive water temperature, rich expressions, smoking, etc. lead to decreased elasticity of fibrous tissue. What are the effective methods for removing crow’s feet? 1, surgery: The principle of surgical crow’s feet removal is to tighten the skin of the temporal region, and at the same time separate the lateral edge of the orbicularis oculi muscle and sew it to a flat position. The surgical method is ideal for removing crow’s feet. 2. Laser treatment: Laser removal of crow’s feet is mainly using ultra-pulse carbon dioxide laser, using its strong beam, instantaneous release, directly radiating heat to the skin to tighten collagen and other subcutaneous tissues, and promote the proliferation of subcutaneous collagen fibers and elastic fibers, so that The skin rejuvenates. Laser crow’s feet wrinkle removal can smooth fine lines and scars to make the skin or scars smoother and remove wrinkles. 3. Hyaluronic acid injection: Injecting hyaluronic acid as a filler into the dermis folds or areas to be plump, such as the corners of the eyes, can achieve immediate wrinkle removal and change the appearance. Hyaluronic acid removal of crow’s feet depends on individual circumstances. The effect of the treatment course can be maintained for a long period of time. However, it should be noted that when hyaluronic acid is injected to remove crow’s feet, a regular hospital needs to be selected, so as to ensure the safety of hyaluronic acid injection for eye wrinkle removal. 4. Injecting BOTOX: For dynamic wrinkles, injecting BOTOX is a simple and safe non-surgical injection method, which makes the skin smoother and fresher. It can also effectively relieve migraine headaches, night sweats and muscle cramps around the neck and eyes. BOTOX is suitable for the removal of dynamic wrinkles. The onset time after treatment is 3-14 days, and the effect maintenance time after treatment is generally 4-6 months. Due to personal constitution, the surgical effect and retention time will be different. Due to individual differences, some customers may experience eye weakness after using BOTOX to remove crow’s feet, and the symptoms usually disappear after 1-2 weeks.  .
Many beauty seekers are not satisfied with the effect of hyaluronic acid injection after finishing hyaluronic acid rhinoplasty, and instead want to undergo surgery for rhinoplasty. So, is it possible to perform rhinoplasty after hyaluronic acid injection? In general, after the injection of hyaluronic acid does not affect the operation of rhinoplasty, but you need to wait for the hyaluronic acid to be completely absorbed or surgically removed. Hyaluronic acid will generally be gradually absorbed after 6~12 months. However, because the injection volume of each person is different from the brand, the absorption time is also different. For those seeking beauty who are anxious to change their nose shape, the waiting time may be slightly longer. In addition, injection of hyaluronidase can be used to accelerate the dissolution of excess hyaluronic acid, and after a period of recovery, the operation can be performed when the state of the nose is relatively stable. It should be pointed out that more and more information now shows that after hyaluronic acid injections, especially after repeated injections, or those who inject too much hyaluronic acid, prosthesis infection and rejection occur after rhinoplasty. The ratio is higher than those who have not done injections. Therefore, if you want to have a tall, permanent and beautiful nose, it may be better to choose a rhinoplasty.
In recent years, the prevalence of high uric acid in China has gradually increased. The prevalence rate varies greatly in different regions, and is generally in the range of 5.46% to 19.30%. That is, in high-risk areas, 1 in 5 people is hyperuricemia. In addition, the prevalence of men reached 9.2% to 26.2%, much higher than the 0.7% to 10.5% of women. Not only that, hyperuricemia also has a clear tendency to rejuvenate. Hyperuricemia has become my country’s second largest metabolic disease after diabetes. Is high uric acid gout? Not really. High uric acid is a prerequisite for gout. Gout will inevitably appear high in uric acid. Usually the first course in the course of gout is asymptomatic hyperuricemia. But only about 10% of people with hyperuricemia have had gout. The higher the blood uric acid level, the easier it is to get gout. However, having high uric acid does not mean that gout will inevitably occur. For example, hyperuricemia is like a pile of dry wood; gout is a fire. The more dry wood, the easier it is to ignite. But with dry wood, it does not mean that fire is inevitable. But once the dry wood is ignited, it is difficult to put out the fire. At present, the best way to extinguish fire is to take away dry firewood. For early patients, in addition to uric acid, he usually has the following characteristics: red: redness and swelling of the skin at the affected joint: swelling and heat of the affected joint: high skin temperature at the affected joint Pain: prominent pain in the affected joint In fact, it also There are some characteristics. For example: the first attack usually involves the first metatarsophalangeal joint, instep, ankle, and knee; night to early morning is a more common attack period; the first attack often has incentives, such as drinking, trauma, vigorous exercise and Cold. People with high uric acid should seek medical treatment as soon as possible. Do I need to lower urine during acute gout? If during the acute gout period, after the use of uric acid-lowering drugs, the blood uric acid suddenly decreases, it will cause the insoluble urate crystals that have been deposited on the joints and surrounding tissues to fall off, causing acute gouty arthritis (also called metastatic arthritis). The sudden decrease in blood uric acid will cause the insoluble urate crystals that have been deposited in the joints and surrounding tissues to fall off, causing acute gouty arthritis (also known as metastatic arthritis). Although the new guidelines believe that uric acid-lowering drugs can also be used in the acute phase, many experts still believe that in the acute stage of gout, it is best not to rush to use uric acid-lowering drugs. It is best to wait for the symptoms of the acute phase to be completely controlled before adding uric acid-lowering drugs. medicine. Does uric acid need further examination? High uric acid often has no special symptoms, so many people will find that they have high uric acid when they get a medical report (usually the index of “serum uric acid” exceeds the standard). According to the definition of hyperuricemia in the Multi-disciplinary Expert Consensus on the Treatment of Hyperuricemia-related Diseases in China in 2017, hyperuricemia was diagnosed when the fasting blood uric acid level on two different days was greater than 420 μmol/L (7 mg/dL). Check-up Tips Corresponding Clinic: Rheumatology, Gout Clinic Initially often performed inspection items: fasting venous blood after the first time that uric acid is found to exceed the standard (greater than 420μmol/L), it is recommended to review the urate level more than one week apart in order to facilitate Diagnosis; patients with hyperuricemia who are younger than 25 years of age and have a family history of gout are also recommended to investigate genetic disorders of purine metabolism. Further examination: usually after the diagnosis is confirmed by the above test, the doctor gives a lifestyle intervention and uses diuretic drugs when necessary. Notes on daily life: Once the inspection finds that the uric acid value is higher than the above-mentioned indicators, it is recommended to adjust your lifestyle in time: encourage more to do and eat more: ➊ drink more water; ➋ can eat more fresh vegetables, eggs and low Fat or skimmed milk, eat some soy products in moderation; ➌Exercise, although exercise can slightly increase blood uric acid, but overall exercise is good for the body; especially exercise can reduce blood uric acid after reducing waist circumference; ➍ can eat some rich Fruits containing potassium and vitamin C, such as cherries, strawberries, pineapples, etc. Should be restricted and avoided as far as possible: ➊ Limit daily calorie intake and control the purine content in food; ➋ Drink less sugary drinks, fruit juices, alcoholic beverages, etc. The best is plain water; ➌ Minimize or avoid drinking and smoking ; ➍ Eat less animal offal, seafood, chicken, duck, fish, etc.; ➎ Try to avoid drugs that cause high uric acid, such as diuretics, oral calcineurin inhibitors (cyclosporine, tacrolimus). Attention to gout treatment (1) Diminish inflammation and relieve pain in time of attack:
The wind is moistening the rain and the green is flourishing. Chuncao loves to dream of flying butterflies, dancing gracefully with Yang and Liu. This poem describes dandelions that are readily available on the roadside in the suburbs or countryside! When it comes to dandelion, I believe everyone is familiar with it. It can fly in the wind, be at ease, or be a home for the whole world, but many people do not know whether it is still a blind Chinese medicine. The medicinal effects of dandelion “The New Compendium of Materia Medica” records dandelion, “It’s cheap and has great merits, but the world doesn’t know how to use it.” From this we can see that dandelion is a very easy-to-use and widely used Chinese medicine, which has several effects worth One mention: 01 clears heat and detoxifies dandelion bitter and sweet cold, its heat clearing and detoxifying effect is commonly used in clinic, also known as “detox grass”. It has a good effect on infection and inflammation, and is often used to treat various diseases such as pharyngitis and conjunctivitis. 02 Reduce liver fire dandelion into the liver meridian, reduce liver fire, when the body shows dry mouth, mouth ulcers, colds, fever, throat pain and other symptoms, you can eat dandelion to relieve. 03 Yang Wei’s “Compendium of Materia Medica” records that dandelion “clears stomach heat without hurting stomach qi”, “clears stomach heat and clears stomach heat”. Modern research has found that dandelion has a broad-spectrum antibacterial effect, can inhibit the Helicobacter pylori, the pathogenic bacterium of gastric disease, and can repair the damage of the gastric mucosa. 04 Diuretic scattered dandelion diuretic scattered, is an important Chinese herbal medicine to reduce uric acid. Among them, dandelion soaking in water is a good choice for health and health tea, lowering fat and acid, preventing gout, and improving arthritis and rheumatism. The addition of dandelion increases the acid-lowering effect of dandelion, also known as “wetting bed grass”, which has a very good effect on diuresis, that is to say, dandelion’s diuretic effect is very powerful. Be aware that two-thirds of uric acid is excreted by the kidneys, so promoting urination is equivalent to promoting uric acid excretion. Daily use of dandelion soaked in water helps to excrete uric acid, while dandelion and magnolia root soaked in water together for better uric acid lowering effect. I have introduced it to you before-Magnolia root is a medicinal plant that my country introduced from Europe to China. It has been included in the Chinese Pharmacopoeia, also known as chicory, which is a plant that is used for medicine and food. Drinking it with dandelion soaked in water can not only promote the elimination of uric acid and prevent gout, but also have a good protective effect on the liver, which can reduce the damage to the liver of taking acid-lowering drugs. Tips: Dandelion is cold, people with spleen and stomach deficiency and qi deficiency should use less!
In the summer, more and more gout patients come to the clinic. And when gout attacks, not only the joints that are invaded will be swollen and hot, but it will even cause a high fever in the whole body, which makes the whole body tremble. Over time, the patient’s joints will gradually be destroyed. So what is gout? Why is there a high incidence in summer? 1. What is gout? The most important biochemical mechanism of gout is hyperuricemia, especially acute characteristic arthritis and chronic gout disease. Under normal circumstances, the body’s uric acid production and excretion are maintained in a good balance, that is, often maintained at a certain amount. But if too much uric acid is produced or excreted too little, it will cause uric acid accumulation in the body. Too much uric acid cannot be dissolved in body fluids, and urate crystals are formed and deposited in various joints, causing red, swollen, hot, and painful arthritis, that is, gout attacks. 2. Causes of gout attacks Although high uric acid may not necessarily cause gout, the higher the index, the higher the risk of gout and the more frequent attacks. Gout caused by several changes in uric acid is common 1) Blood uric acid suddenly rises in the short term: uric acid Crystals precipitate in the synovial fluid of the skin and joints, urate crystals chemotactically leukocytes, release inflammatory factors and hydrolytic enzymes after phagocytosis, leading to acute attacks.  . . . . . . . . . . . . . . 2) The blood uric acid drops too fast in the short term: “melt ice” phenomenon, gout stone dissolves, releasing insoluble needle-like crystals , Induce an acute inflammatory response. Common reasons are: the use of uric acid-lowering drugs such as allopurinol, febuxostat, benzbromarone, etc. declines too quickly in the short term. 3) Local joint disease leads to decreased solubility: for example, joints are stimulated by cold to cause peripheral blood to decrease, and uric acid decreases in local solubility, especially in summer when the temperature of the air conditioner is low or the fan continues to act on the joint. 4) Local lesions of the joint lead to increased vascular permeability: joint strain, infection, etc. lead to the release of local inflammatory mediators, the microcirculation permeability increases, and uric acid deposits from the blood vessels into the tissue according to the concentration gradient, which induces an acute attack. 5) Alcoholism: Ethanol metabolism increases blood lactic acid concentration, lactic acid inhibits renal tubular excretion of uric acid; excessive intake of alcohol accelerates ATP decomposition and increases uric acid synthesis. 3. Factors that easily lead to high uric acid in summer 1) Staying in a low-temperature environment for a long time The temperature in summer is high, people are more willing to stay indoors with air conditioning. If the temperature of the air conditioner is too low or the distance to the air outlet is too close, urate is more likely to precipitate crystals in a low temperature environment and deposit around the joints, resulting in the onset of arthritis. Therefore, patients with high uric acid must avoid cold in summer. When gout attacks, you can apply a warm towel to the affected area to reduce pain, or pay attention to adjust the temperature of the air conditioner in summer, not too low! 2) There is a high chance of trauma in summer. In summer, people wear light and thin clothing, and the exposed area of the skin is large. It is easy to be traumatized. A little care may cause trauma infection. When a traumatic infection occurs, the metabolic function of the body will change accordingly, resulting in increased uric acid and trigger gout. Therefore, when going out in summer, you should take good protection to reduce the occurrence of bumps. Once there is a trauma, it should be disinfected in time. If an infection occurs, it should be dealt with in time. 3) The summer is hot and the amount of sweating is large. When the weather is hot, the body sweats a lot. If the water supplement is insufficient or not timely, the blood will “concentrate” and the uric acid in it It is easy to deposit and precipitate, which can cause gout. So when you sweat a lot in summer, you need to drink more water, reaching about 2000ml per day. However, it should be noted that drinking water is recommended to be boiled water. If you drink sweet drinks, coffee, etc., it is not conducive to controlling uric acid. 4) Summer gout diet: Beer drink crayfish is a good time to eat seafood and drink beer in summer. Once in the summer, beer and drinks are people’s favorite drinks to understand the summer heat. Not only quenches thirst, but cold beer is drunk, and the whole body feels When it feels cold, but alcohol enters the body and is metabolized to produce lactic acid, which inhibits the discharge of uric acid, which can easily induce gout. It is also a perfect match with crayfish, a summer diet. However, many patients with high uric acid are recruited. Drinks also need to pay attention to the diet, because the drink contains a lot of fructose components, the decomposition process of fructose in the body will directly produce uric acid, which is equivalent to increasing the source of endogenous uric acid. At the same time, fructose will reduce renal uric acid excretion, further causing the body Uric acid is elevated. Under this double influence, the body’s uric acid level will remain high
Diabetes and hyperuric acid are associated with each other. “In recent years, the prevalence of hyperuricemia in China has continued to rise. Among metabolic diseases, more patients have hyperuricemia. The survey shows that 25% of diabetic patients Complicated with hyperuricemia, this is due to the “blood connection” of glucose metabolism and uric acid metabolism. When urate is deposited on the pancreatic islets, it can lead to impairment of β-cell function, induce and aggravate insulin resistance, trigger disorder of glucose metabolism, and eventually lead to diabetes. Studies have shown that the risk of type 2 diabetes increases with the increase of blood uric acid levels. Diabetes can lead to hyperuricemia. It can be said that diabetes and high uric acid are accompanying “difficult brothers and brothers”. For hyperuricemia and diabetes, both have a common risk factor: obesity. Insulin resistance and dyslipidemia are more pronounced in patients with diabetes and hyperuricemia, glomerular filtration rate (e-GFR) is lower, and the harm is greater. Sugar friends encountered hyperuricemia, how to choose hypoglycemic drugs? In the selection of hypoglycemic programs for patients with diabetes and high uric acid, in addition to the hypoglycemic effect, blood uric acid levels must also be taken into account. The principle of multidisciplinary combined treatment should be followed, and drugs with uric acid lowering effects should be selected in a targeted manner. Achieve the effect of two birds with one stone. 1. Insulin Insulin is a common drug for patients with diabetes, but insulin can promote the synthesis of liver uric acid and the reabsorption of uric acid by the kidneys, inhibit the excretion of renal uric acid, and increase the blood uric acid level. Therefore, patients with diabetes and high uric acid should use insulin with caution. If diabetes requires long-term use of insulin therapy, it is recommended to use insulin sensitizers, biguanides, and alpha-glucosidase inhibitors in combination with blood uric acid levels, and uric acid-lowering drugs if necessary. 2. Insulin sensitizers such as pioglitazone and rosiglitazone both have the effect of reducing uric acid and protecting the kidneys, so it is recommended for patients with diabetes and hyperuric acid. 3. Biguanide antihyperglycemic drugs The classic antihyperglycemic drug metformin, which has both hypoglycemic and weight-reducing effects, has long-term use and has a uric acid-lowering effect, so patients with diabetes and high uric acid are recommended. 4α-glycosidase inhibitors such as acarbose (abasin) can reduce the increase in blood uric acid levels caused by the breakdown of sucrose, and can be used by patients with diabetes and high uric acid. 5 Insulin secretagogues sulfonylureas (such as glibenclamide, glimepiride) and mealtime blood glucose regulators can increase serum insulin concentration, affect the metabolism and excretion of uric acid, and raise blood uric acid levels, so it is not recommended in the clinic use. 6. Sodium-glucose co-transporter-2 (SGLT-2) inhibitors such as dapagliflozin, englitazone, and caglitazone can both reduce blood uric acid and control blood sugar to varying degrees. SGLT-2 inhibitors have a moderate reduction in serum uric acid levels and are used as a potential supplement for lowering uric acid. The benefit of SGLT-2 inhibitors in gout disease is more worth looking forward to. Patients with mild liver and kidney dysfunction do not need to adjust the drug dose of SGLT-2 inhibitors, and are contraindicated in patients with severe renal impairment [e-GFR<.30mL/(min•1.73m2)] or dialysis patients. SGLT-2 inhibitors are all oral drugs, administered once a day, morning, fasting or after eating. A few days ago, the blood sugar-reducing drug Daglijean of the “soul bargaining” of the National Medical Insurance Bureau was one such kind of medicine. A 10mg tablet was 4.36 yuan. Dagresi has a very strong hypoglycemic effect and is fasting for patients with type 2 diabetes Both blood sugar and glycated hemoglobin have a significant lowering effect. The mechanism of reabsorption of glucose and uric acid in the renal tubules is very similar to that of the site. Daggliflozin inhibits the reabsorption of urinary sugar while also inhibiting the reabsorption of uric acid. Studies have confirmed that dagligliflozin can reduce blood by 10%-15% Uric acid levels. Because there are no data on the use of SGLT-2 inhibitors among minors, pregnant women and lactating women, it is not recommended for use in such populations. The main adverse reactions of SGLT-2 inhibitors are genitourinary tract infections, mostly mild to moderate bacterial or fungal infections, and conventional anti-infective treatments are effective. It is recommended that patients pay attention to personal genital hygiene, drink water in an appropriate amount, and keep the urine clear, which can reduce the incidence of infection. 7. Other drugs Glucagon-like polypeptide-1 (GLP-1) receptor agonist (liraglutide, exenatide), dipeptidyl peptidase 4 inhibitor (DPP-4) Ting, vildagliptin): can improve islet function, reduce insulin resistance, will not cause blood uric acid to rise, and can even pass
Hyperuricemia is a metabolic disease caused by purine metabolism disorders, which is the most important basis and direct cause of gout. With changes in lifestyle and diet, the prevalence of hyperuricemia and gout continues to increase, seriously harming the health of patients. What are the common problems in clinical diagnosis and treatment? 1. What is hyperuricemia? Hyperuricemia refers to the fasting blood uric acid level on two different days under normal purine diet, male>420μmol/L, female>360μmol/L. Uric acid is the final product of purine metabolism. About 80% of uric acid in the human body is endogenous purine metabolism, and about 20% comes from purine-rich foods. The main reasons for the formation of hyperuricemia are: (1) Excessive production of uric acid, such as high purine diet and drinking. (2) Decreased excretion of uric acid, such as chronic kidney disease, metabolic syndrome, etc., among which excretion disorders are predominant. (3) Mixed type, excessive uric acid production and reduced discharge. 2. Will hyperuricemia develop gout? Gout is due to long-term purine metabolism disorders, and increased blood uric acid causes urate crystals to deposit in joint tissues, causing inflammation. Increased blood uric acid levels may not necessarily cause gout, but hyperuricemia is the most important biochemical basis of gout, and urate crystal deposition is the result of hyperuricemia. Gout has obvious heterogeneity. In addition to hyperuricemia, it can be manifested as acute arthritis, gout stone, chronic arthritis, joint deformity, chronic interstitial nephritis, and uric acid urinary calculi. 3. What conditions need uric acid lowering treatment? There are no cardiovascular risk factors. When blood uric acid> 540 μmol/L, generally, uric acid lowering treatment should be started on the basis of improving lifestyle; there are cardiovascular risk factors such as gout and diabetes, male> 420 μmol/L, female> 360 μmol/ L, generally should start uric acid lowering treatment on the basis of improving lifestyle. 4. What are the drugs that affect uric acid levels? Elevated uric acid: NSAIDs, hydrochlorothiazide, insulin, cyclosporine, mercaptopurine, penicillin, moxifloxacin, vitamin C, vitamin B1, cyclophosphamide, oxaliplatin, etc. Urinary acid excretion: losartan, fenofibrate, calcitonin, reserpine, estrogen, glucocorticoid, etc. 5. How to intervene through lifestyle? (1) Maintain a healthy lifestyle and avoid ingesting high-purine foods (such as animal offal, seafood, broth, dried peas, etc.); (2) Drink 2000-3000mL of daily water, quit smoking and limit alcohol (beer, liquor); strengthen exercise , Reasonable rest, control weight; increase intake of alkaline foods such as bananas, pumpkins, apples, radishes, etc. 6. When do you start medication? After 3 months of non-drug treatment for patients with gout, blood uric acid ≥420μmol/L, gout patients with blood uric acid ≥360 (severe cases ≥300) μmol/L, should be treated with urate-lowering drugs. 7. What are the commonly used therapeutic drugs? Before uric acid lowering treatment, the type of elevated uric acid (excess uric acid production type, reduced uric acid excretion, mixed type) should be clarified, and the drug should be selected according to the 24-hour uric acid and blood uric acid levels. (1) Treatment of colchicine in the acute stage of gout: To prevent the activation, degranulation, migration of neutrophils, common diarrhea, bone marrow suppression, liver cell damage, allergies and other adverse reactions. Periodically monitor blood routine and liver and kidney function during medication. Non-steroidal anti-inflammatory drugs: inhibit cyclooxygenase activity, block the conversion of arachidonic acid to prostaglandins, common gastrointestinal discomfort, selective COX2 inhibitors can be preferred to reduce the occurrence of adverse reactions. Glucocorticoids: To reduce and prevent inflammation, common gastrointestinal discomfort, weight gain, leukocytosis, allergic reactions and other adverse reactions. During the acute attack of gout, nonsteroidal anti-inflammatory drugs, colchicine, and glucocorticoids should be used early and in sufficient amounts. Glucocorticoids are generally used in people who cannot tolerate colchicine, non-steroidal anti-inflammatory drugs, and renal insufficiency. Generally, uric acid lowering treatment is started after 2 weeks of relief of acute symptoms, and uric acid lowering treatment can also be started immediately on the basis of acute phase anti-inflammatory treatment to maintain blood uric acid within the target range. To avoid fluctuations in blood uric acid, those who have taken uric acid-lowering drugs do not need to stop it during acute attacks. (2) Inhibition of uric acid production of allopurinol: By inhibiting xanthine oxidase, reduce uric acid production. The initial dose of the tablet for adults of this medicine is generally 50 mg once, 1 to 2 times a day, and it can be increased by 50 to 100 mg a week to 200 to 3 a day.
How hot is the Shuiguang needle, I don’t believe I need to introduce it. Every girl must have a friend who has been injected with a water light needle, and the effect of the water light needle is also immediate. According to a related survey of the Korean plastic and beauty industry, 95% of Korean entertainers regularly perform skin light injection to maintain their skin at their best. Shuiguang injection has become a very popular medical and aesthetic project and is popular all over the world. What is the magical charm of Shuiguang needle? Shuiguang needle is not only used to replenish water, it has the following major effects. 1.  . . . . .Improve skin textureImprove dull skin and diminish freckles and other pigmentation. Delicate pores to solve the problem of putting on and removing makeup. Second, enhance elasticity and anti-aging to improve fine wrinkles and enhance facial elasticity. Especially for women after the age of 25, the collagen loss on their faces is getting faster and faster, and it is very necessary to start anti-aging. Improves skin aging and moisturizes and tightens the skin.  . 3. Moisturizing and rejuvenating skin improves the feeling of tightness behind the cleansing face, deeply hydrates and locks in the skin, and improves the problem of dry skin caused by seasonal changes. Little popular science: The content of hyaluronic acid in the human body is about 15g, which plays an important role in the physiological activities of the human body. As the content of hyaluronic acid in the skin decreases, the skin’s water-retaining function will weaken, appear rough and produce wrinkles. Shuiguang injection is to inject hyaluronic acid with 500 times the moisture into the skin, which can make the facial skin moist and soft, and the gloss is translucent to bring obvious effects.  . Water injection process:  . Water injection is not a surgery, generally facial injection, 10-15 minutes. It does not affect normal life at all. It is injected through the dermis layer during injection to improve skin problems from the bottom. After doing it, there will be no adverse reactions, you can operate the whole face.  . Many people feel that the water light injection will hurt, in fact, the vacuum negative pressure on the water light needle can reduce the pain, and the epidermal anesthetic will also reduce the discomfort of the needle. However, there will be some tingling sensation during the injection, which is within the acceptable range. Shuiguang injection uses the thinnest needle in the world, the 31g needle, the thinner the needle, the less painful it is. It may be similar to the injection we had when we were young, and the duration will be longer. Is water injection a hyaluronic acid injection? Actually not. There are 3 kinds of water-light needles commonly available on the market: 1. Hyaluronic acid: once a month, the effect of a course of treatment (3 times) can be maintained for about 1 year. Different brands have different concentration formulas and different durations. Hyaluronic acid is the most basic formula. It has moisturizing, whitening, shrinking pores and anti-allergic effects. 2. Hyaluronic acid, botulinum toxin: once a month, the effect of a course of treatment can be maintained for about 1 year. It can also prevent stiffness and unnatural phenomena when used with the water light needle machine. Based on the function of hyaluronic acid, it increases wrinkle removal, anti-wrinkle, enhances and increases skin elasticity. 3. Hyaluronic acid, prp: once a month, the effect of a course of treatment can be maintained for about one year to one and a half years. What is prp? Platelet (platelet), rich (rich), plasma (plasma), refers to rich growth factors. Such growth factors can guide the regeneration of collagen in the skin and fundamentally solve skin aging, wrinkles, spots and pores. Shuiguang needle is so magical, is it effective immediately after finishing it? The normal metabolic cycle of the skin takes 28 days, so it takes at least a week or so to see the effect after the water light needle injection. After completing the first time, you can do the second and third times in one month. The three times are a course of treatment, and the course can be maintained for about one year to one and a half years.  . After finishing, the skin will be slightly red, swollen and slightly bleeding, because the skin absorbs hundreds of times of molecules at once and needs to adapt. The second day may be redder than the first day, which is normal clinical manifestation. After finishing, apply a mask on your face, and then apply anti-inflammatory repair products, it will return to a better state in about seven days. I will share it here today. If you have any questions, please welcome private messages and comments, or add my assistant WeChat. You can find her for appointments and consultations.
I suggest that it is best not to inject hyaluronic acid at the site of lying silkworm. Although this is the simplest method, and many Jianghu studio beauty salons are doing it… But from a professional point of view, I do not advocate the use of hyaluronic acid! A brief analysis: Hyaluronic acid is like water, and the skin of the lower eyelid is very thin, especially unnatural after injection, and it will be a bit like an eye bag! In addition, after a few months, the hyaluronic acid will be absorbed, and the skin of the lower eyelid will be stretched out, and it will leave fine lines after it has collapsed. Therefore, be prepared in advance. Fengwo silkworm should use permanent methods as far as possible. One is to use the orbicularis fold of the lower eyelid. This kind of surgery is most suitable for forming a lying silkworm while doing an external eye bag. It is a double benefit. This also removes excess skin from the lower eyelid, while retaining the tissue of the orbicularis oculi muscle. The important thing is that this lying silkworm will look more obvious and real, and it will also look more energetic. The second is to fill the lying silkworm with a small amount of fat. The size and shape of the transplantation can be determined according to your own requirements, but it is recommended that you do something natural. When you don’t laugh, you lie a little. When you laugh, there are obvious lying silkworms. Lying silkworm close to nature. It is a good partner with the lower eyelid. Although I don’t recommend the operation of the lower eyelid to the eye, because the lower eye has higher requirements for the eye, so if there is a need for lying silkworms, you can consider both. I must also emphasize that when removing eye bags, do not blindly pursue the amount of peeling. It is also beautiful to ignore the bulging of the lower eyelid. If the tissue of the lower eyelid is removed too much and the lower eyelid is too flat, it will look like it will Even older! Therefore, at the same time of repairing, by rebuilding the lying silkworm, the situation of the lower eyelid being too flat can be well improved, and the effect is the best. It is very important to choose an experienced and high-level doctor. I think that any plastic surgery that has a problem is the result of my carelessness. There are many cases of lowering of the lower eyelid caused by lying silkworm injection! Therefore, I also hope that everyone will learn more about plastic surgery while loving beauty and be responsible for their own health and safety!