Shi Shurong’s Medical Talk: After bone marrow transplantation in patients with aplastic anemia, what issues need attention?

Bone marrow transplantation is currently one of the main clinical treatments for acute leukemia, severe aplastic anemia and other diseases. Since the implementation of bone marrow transplantation, many patients with hematological diseases have chosen to transplant. However, the success rate of bone marrow transplantation is not 100%, and many problems still need to be paid attention to after transplantation. Director Shi Shurong’s WeChat consultation platform: zkxk9999 leukemia patients after bone marrow transplantation Note: 1. Within 3 months after transplantation, it is best to see the clinic once a week. 2. Mainly draw blood to check blood picture, liver and kidney function, blood sugar, cyclosporine or tacrolimus concentration, cytomegalovirus, etc. 3. When checking the concentration of cyclosporine or tacrolimus, pay special attention to the time of blood drawing, such as taking medicine at 9 o’clock the night before, and drawing blood at 8 o’clock the next day. Do not draw blood after 9 o’clock. The results will mislead the doctor. 4. Within three months, it is best to check the bone penetration every month for small residues. Adjust the dose of anti-rejection drugs and reduce anti-rejection drugs according to the results. 5. The three internal rejection reactions mainly depend on the skin and liver function. You should also pay attention to eating, mainly because you are afraid of eating a bad stomach, which is confused with rejection. 6. After three months, it is mainly chronic rejection, mainly manifested as rash, oral ulcers, dry eyes, and abnormal liver function. Usually pay attention to see if the color of urine is yellowing or white eyes are yellow, and be alert for jaundice in advance. Chronic rejection diarrhea is rare, but there will be, so you must pay attention to eating. The principle is to be clean. The difference between aplastic anemia and leukemia after bone marrow transplantation requires special attention: 1. Aplastic anemia bone marrow transplantation is mainly due to the undesirable rejection after transplantation. 2. In order to prevent rejection after transplantation, anti-rejection drugs must be slowly reduced. 3. Check the concentration of anti-rejection drugs after transplantation to ensure the effective therapeutic concentration. If there is no rejection after half a year, then slowly reduce the drug. Generally there is no rejection in 1 year and the drug can be stopped. If rejection occurs during treatment, first check if the drug concentration is sufficient. Then add other drugs, such as hormones. In summary, after bone marrow transplantation does not mean the end of treatment, there are some follow-up treatments to be carried out. I hope that patients with aplastic anemia will actively prevent disease recurrence, reduce the chance of infection, and actively respond to immune rejection reactions after bone marrow transplantation. In order to improve the success rate of bone marrow transplantation. More patient communication help can pay attention to the WeChat public account: Reinsertion Patient Association

Not every MDS patient is suitable for hematopoietic stem cell transplantation

Hu Guisheng Assistant WeChat: dd326751 Source: Transferred from WeChat public account [Hu Guisheng Studio] MDS, which is myelodysplastic abnormal syndrome, is a disease that is not easily cured by the blood system and has the characteristics of high-risk to acute leukemia. The simplicity can be mainly manifested as anemia, or anemia, leukopenia and the reduction of platelets, the prognosis is also different. According to the different somatic cell products invaded, the number of primitive cells and their karyotypes are different, MDS is divided into low risk, medium risk and high risk. For low-risk patients, the mean survival period is around 5 years, and for medium-risk patients, the mean survival period is around 2 years. However, for high-risk patients, the mean survival period is less than half a year.  When MDS is at high risk, hematopoietic stem cell transplantation is still recommended. If hematopoietic stem cell transplantation is successful, it is a good message. In fact, it can continue its own life. However, after getting sick, it will not become more and more physically and mentally healthy as before. Therefore, even if hematopoietic stem cell transplantation is successful , Also depends on their own situation.   Generally speaking, the current MDS treatment should be based on the risk group to decide the treatment plan and strategy. Treatment of MDS patients in the relatively low-risk group includes supportive therapy (component blood transfusion, hematopoietic factor therapy), immunomodulators, demethylation therapy, and traditional Chinese medicine therapy. Chemotherapy and hematopoietic stem cell transplantation are generally not recommended. Patients in the relatively high-risk group require high-intensity treatment, including combination therapy, demethylation, chemotherapy, and hematopoietic stem cell transplantation, but high-intensity treatment, such as chemotherapy transplantation, has higher treatment-related complications and mortality, and is not suitable for all patients. .   In addition, there is another very important point, that is, the age span of MDS is relatively large. In my country and Asia, the age of onset tends to be younger. There are a small number of children and adolescents with MDS in clinical practice, and some adults have MDS, but most of them are still sick for the elderly. Therefore, when formulating treatment plans and measures, in addition to the prognostic scores of MDS patients, a comprehensive assessment should be made based on the patient’s age, physical condition, comorbidities and accompanying diseases, treatment willingness and compliance, etc., and select an individual treatment plan. To suit every patient and prevent over-treatment and under-treatment.

Why are there so many young girls losing hair now?

Why do more and more people suffer from baldness and hair loss, and even the hair loss of the younger generation after 90s has become more and more serious? Hair loss manifests itself in that the speed of hair loss is greater than the speed of hair growth, and the balance between hair loss and hair growth is broken. In the final analysis, the growth of hair follicle cells is hindered. There are many reasons for hair loss. Genetic factors, seborrheic alopecia, chronic diseases, endocrine disorders, excessive brain use, stress, dietary malnutrition, hair style effects, etc., may all cause hair loss. &nbsp. Focus on this, why do girls lose hair? &nbsp. Reason one: Androgenic alopecia is also called seborrheic alopecia, AGA in English, and FAGA in women. Although male hormones are written, it is possible for women to develop the disease (don’t doubt, women also have male hormones), the probability is about 60%. Although compared with men, women’s symptoms will be slower and the symptoms will be milder. It usually starts at the age of 20, and the high incidence age is around 50 years old, which means that the young and middle-aged time is the key period. And this is a genetic factor, which is considered a genetic disease, so a cure is impossible. The whole process starts from the forehead or the top of the head, and the hair follicles of the original healthy hair begin to shrink into thin, short and fragile hair with atrophy, and then start to fall. &nbsp. Reason two: Nutrient metabolic alopecia Many girls will also diet and lose weight, in fact, this may be the root cause of hair loss. Hair loss occurs when the business intake is not balanced, such as protein deficiency, iron deficiency, zinc deficiency, excessive selenium, etc. In addition, certain metabolic diseases such as arginine succinic aciduria, homocystinuria, hereditary orotic acid Urinary disorders and methionine metabolism disorders are also the causes of hair loss. So if you want to have a lush hairstyle, you must pay attention to the intake of nutrition. The girl who wants to lose weight and lose hair must be crying. Can she have both thin and hair? ! Don’t worry, Xiaoxiao sauce will bring you several medical and aesthetic methods to deal with hair loss. I believe there is always a way for you! &nbsp. Surgical Treatment-Hair Transplantation Hair transplantation is to transplant the hair, and cut the tissues around the hair follicle together to remove it from the original position of the scalp, and then transplant it to the location where the hair needs to be increased. In fact, it is essentially a method of “demolition of the east wall to make up the west wall”, but at least visually it seems that the hair has become even and beautiful. There are two methods of hair transplantation-FUT method and FUE method. Remember, there are only these two methods in the world at present, and the rest of the strange technologies are mostly hospital gimmicks. The FUT method, full name follicleunittransplant, is the transplantation of hair follicle unit, that is, the hair follicle flap is extracted from the posterior occipital region, the hair follicle unit is cut and separated, and implanted in the receiving area. To be more clear, it is to cut a scalp about 1cm wide and divide it into hair follicle units with a magnifying glass. Each unit has about 3-4 hairs and is placed in the hair transplantation area with instruments. The damage to the scalp is small, but because the wound that needs to be sutured to extract the hair follicle flap will affect the donor area, leaving a strip of scar. But don’t worry too much, this is not so exaggerated, as long as you don’t shave your hair, you can only see the white scar. FUT hair transplant technology has extremely high requirements for the technical level and stunning of hair transplant doctors, but the adapted hair transplant area is also relatively large, and the survival rate of hair follicles is high. Generally, an operation can last 3000-4000 roots, and the price is relatively cheap. The full name is follicleunit extraction, also called hair follicle unit extraction, that is, the hair follicle unit is directly extracted from the back pillow part, and the hair follicles are separated and cultivated, and then implanted into the receiving area. In this way, the hair follicles are taken directly, and no special treatment is needed on the scalp. The scalp will heal automatically after taking out, without suture and suture removal, which is similar to the feeling of transplanting rice seedlings. This hair implant technology is more suitable for small-scale hair transplantation, more delicate, suitable for hairline, eyebrows, temples and other parts of the transplant, and the price is relatively high, the advantage is no scars after surgery, the wound is punctate, fully automatic healing pain. In addition, FUE surgery can be transplanted with hair from other parts of the body, such as chest hair, hand hair, leg hair, etc., but the characteristics of the hair follicles removed may not be the same as the original parts, so it may not be completely suitable. &nbsp. Tong reminds everyone that any operation is risky, I suggest you go to a professional and regular hospital to choose an experienced one

What are the precautions after hair transplant?

&nbsp.&nbsp.&nbsp. Polluted living environment, stress at work and life, diseases and other factors can cause hair loss. No one wants to have convex light on their heads, so hair loss patients will choose hair transplantation to regain their lush hair. Take a look at what you need to pay attention to after hair transplantation. &nbsp.  Hangzhou Shiguang Plastic Surgery Hospital experts said that hair transplantation is a delicate surgical operation, which has very high requirements for doctors’ experience and technology. Many patients choose the wrong hospital, causing waste of hair in the supply area, which leads to surgery failure. Therefore, please choose a regular medical institution for hair transplantation to ensure hair transplantation.  Precautions after hair transplantation:    1. Due to the use of narcotic drugs during hair transplantation, nausea, vomiting, fatigue and other discomfort may occur, so take more rest.   2. After the hair transplantation, the doctor’s orders must be kept in mind and executed according to the doctor’s orders to recover smoothly and reduce postoperative discomfort.   3. Use a higher pillow when sleeping.   4. Do not exercise within 5 days after hair transplantation, avoid vigorous exercise for 3 weeks, and pay attention to protect the operation area.   V. Return to the hospital on the second day after hair transplantation for reexamination and dressing change.   6. Hair washing cannot be done within 4 days after hair transplantation. After 4 days, the hair can be shampooed and the hair transplant area should be rubbed gently.

Can hair transplant make hair thicker?

&nbsp.&nbsp.&nbsp. Most female friends with fine hair do look pretty good, but male friends generally don’t think so, so male friends with scarce hair use a variety of methods to improve hair quality. For example, hair milk, ginger, etc., but none of them can achieve good results, so can hair transplantation make the hair thicker? Let’s take a look at the science of experts in Hangzhou Time Plastic Surgery Hospital. &nbsp.   Many friends have lost their favorite jobs and people they like because of their hair scarcity. Scarce hair can make people feel more exhausted, without the vitality of young people, so many people are very worried about hair problems. How to solve the problem of hair thinning? Hair implant surgery can help you solve the problem of hair thinning. 1. The hair transplantation is sexual hair transplantation, which is the self-existing hair that lives on the skin of the body and will not fall off. It is completely consistent with the hair nature and growth rule of the original hair supply site. Second, the hair that is initially planted has a rest period. It takes about 3-6 months, and the hair just planted during the rest period may still fall off, but the hair planted after the rest period begins to recover and new hair grows.   3. The survival rate of autologous hair transplantation is high.    4. Autologous hair transplantation process is not painful and very safe.    5. Autologous hair transplantation does not produce scars.

What should I do when the fat transplant is overfilled?

In general, we will worry about the survival rate of fat, but in very rare cases, the transplanted fat may also be longer. The metabolism of fat after it survives may increase with weight gain. This fat growth beyond expectations may destroy the proportion of the face or make the face look less beautiful. This is a physiological increase and generally does not require treatment. Sometimes, the transplanted fat may be abnormally proliferated under the stimulation of various factors (the specific cause is unknown), forming lipoma-like hyperplasia. If the formed lipoma-like hyperplasia grows longer, you can use a liposuction tube to insert it into the tumor to suck it, or surgically remove it. In addition, adding growth factors during fat transplantation may promote the production of lipomas. Therefore, when doing fat transplantation, you should avoid adding any growth factors. Fat transplantation is generally over-transplanted, but if the survival of the transplanted fat exceeds the expected, it may cause local fat excess, manifested as bloated area. When there is an excessive amount of fat-filling, the fat metabolism can be accelerated by hot compresses, infrared therapy, etc. in the early stage. However, the fat is still in the absorption phase early after the operation, and the face is swollen. It is not easy to judge whether it is really excessive. Therefore, it is recommended not to deal with it in a hurry, you can wait for 3 months to stabilize before processing. If the survival amount of fat is indeed too much, excess fat can be eliminated by methods such as lipolysis or liposuction.

After the disaster, cherish the hard-won success

On August 27, 2017 (Lunar Calendar), this day was originally a happy day, because this day is my birthday, but the facts are not there. On this day, I was medically identified as chronic suicide-uremia. On the day of the diagnosis, I felt that it collapsed in just a day. This birthday gift came too abruptly and could not be refused. I have since embarked on the path of dialysis. I used to work on site at the construction site, and the work was heavy and tiring. Since I became ill, I could only retreat to the second line and go to the office to do some relaxing work. The company has staff quarters, but in order to have a better dialysis environment In order to avoid infection, I rented a house next to the construction site and returned to rent a house to change my water after eating. Both work and life were correct. During the dialysis time of nearly 3 years, my small problem was constant, but the big problem never happened. I immediately consulted the doctor and the doctor adjusted the medication, and it took 3 years. With the support of family, relatives and friends this year, I am going to have a kidney transplant. At the beginning of the year, I went to major hospitals to line up for matching. Maybe the goddess of fortune saw me pitiful, and gave me good luck. I queued for a month and received The hospital’s phone said that the matching was successful and the transplant operation was possible. Upon hearing this news, I was so excited that I couldn’t speak. I thank my family and relatives and friends for giving me a chance to be reborn. On the day of the operation, I was nervous and excited. I was nervous because it was a major operation or there was a certain risk. I was excited because my quality of life would improve a lot after the transplant. On August 13, 2019, on this day, I successfully completed the transplant operation. The operation was very successful, and the recovery was very good after the operation. There were no adverse reactions. In order to facilitate the postoperative examination, the family rented a house around the hospital and let me live when I was discharged. I have just been discharged from the hospital and now I feel that everything is in good physical condition. The six months after transplantation is a very special period. I must listen carefully. Doctor, protect my kidney baby, because this is my rebirth! Since the transplantation has just finished, the living environment should be ventilated and the air is good. Try not to go to a densely populated place. You must wear a mask when you go out. So after transplantation, I have been resting at home, not working, and it takes about six months to a year of rest. Life starts again from now on, and hopes that the future will get better and better.

How can transplantation treat aplastic anemia be completely cured?

Transplantation is one of the means to cure aplastic anemia. The treatment process is smooth and the effect is immediate. However, because of the high sensitivity stage after transplantation, patients may have a certain recurrence rate. To what extent should this be considered a complete cure? One question-how long after transplantation of aplastic anemia? Generally speaking, even if it is cured without recurrence within 5 years after transplantation, the longer the normal duration after transplantation, the lower the relapse rate will be, and there are very few cases of aplastic anemia recurring after five years. In addition, aplastic anemia is not a malignant hematological tumor. Once this time is reached after successful transplantation, there will be very few cases of recurrence in the future. For aplastic patients who are ready to transplant, during and after transplantation. Can only be psychologically prepared, listen to doctor’s advice, do a good job of prevention and a reasonable life. Regulate the influence of medication and anti-rejection drugs before and after the transplantation process to ensure good disease resistance, so that the recovery rate after transplantation will be much higher! Although the treatment of aplastic anemia can not be as common as common cold and fever, it is believed that with the advancement of science and the development of medical technology, more and more patients with aplastic anemia will recover their health and completely get rid of drug dependence. If you have any questions about this article or the disease, please feel free to follow us on WeChat and find out more: xuf120

Do you have a bone marrow transplant if you have leukemia?

Many people think of “bone marrow transplantation” as soon as they talk about leukemia. It is believed that chemotherapy has large side effects and is easy to relapse. The late treatment is long and the time spent is higher than that of money, but bone marrow transplantation can be “quoted.” In fact, it is a misunderstanding that leukemia patients must transplant bone marrow! We often hear on the Internet that leukemia patients are looking for a suitable bone marrow matching, or because of the high cost of surgery, they cannot be operated on. Therefore, in the impression of many people, leukemia and bone marrow transplantation are closely linked. Without proper bone marrow matching, patients can only wait to die. Nowadays, in the medical research field of leukemia, modern medicine has been able to provide different treatments for different types and degrees of leukemia. With the continuous improvement of leukemia treatment research, the treatment of leukemia is becoming more standardized. Doctors can choose different treatments and different medicines for precise treatment according to the patient’s condition, age, and actual physical condition. When choosing a combined Chinese and Western medicine treatment plan, they can help the patient to a greater extent. This is also the domestic The value and significance of the existence of the integrated western medicine hospital. Regarding bone marrow transplantation, it is necessary to rationally assess the consequences. We must realize that bone marrow transplantation is not the only option. At the same time, the treatment effect is limited and there are still certain risks, because this may affect the patient’s future life, so please everyone It must be remembered: transplantation has a price, and rejection is priceless! Follow me to learn more about the science of hematology.

The case of good pregnancy: five years of infertility, looking for the hope and miracle thousands of miles away!

Help more families who are difficult to walk in the dark to see the dawn, accumulate strength, and move forward bravely. A good pregnancy case △ Case introduction Good pregnant mother: Ms. Qian Difficult treatment: bilateral salpingectomy, repeated transplantation failure, continuous transplantation Basic situation: Not pregnant for 5 years after marriage; after multiple hospital visits, none of the three transplants were pregnant, and the gynaecology and obstetrics hospital succeeded in pregnancy after one egg retrieval and two transplants. The rash decision to ruin my life dates back to 2014. My boyfriend and I were married and worked together in Heilongjiang, but we are in the rising stage of work and we are not going to have children for the time being, but we did not take any contraception after marriage. Measures, I was pregnant in just one year, and we gave up the first child temporarily for the sake of discussion. At that time, I could not have imagined what kind of trouble this sloppy decision would bring to my future life. In an instant, after 2016, when our work was relatively stable, we began to prepare for pregnancy. For more than a year, I checked various good pregnancy tips on the Internet and in the book, and tested my ovulation period every month. Scientific In the same room as her husband, she is still not pregnant. The elders at home suggested that I could be a test-tube baby. I was fed up with bumping back and forth all day long in hope and disappointment. In addition, my sister’s sister was a baby born after a successful test tube. Now 6 years old, he is healthy and cute, so I accept it The proposal from home. I thought the success rate of the test tube would be high, but I did not expect the test tube to be just the beginning of another suffering for me. The test tube road is difficult and dangerous. In 2017, we went to the local hospital for examination. The test result was hydrops in the fallopian tube. This is also the result of long-term pregnancy failure. After a period of treatment, I underwent IVF treatment in October 2017, and the first transplant failed after egg retrieval. In July 2018, due to severe hydrops in the fallopian tube, the doctor said that the fallopian tube function has been completely lost, and the fluid in the fallopian tube will affect the implantation of the uterine cavity and affect the embryo implantation. In the same month, I underwent bilateral salpingectomy; early 2019 Another two transplants in the hospital ended in failure. In order to have children, my husband and I ran around and worked for four years, exhausting my savings for several years. During that time, I was affected by various negative and negative emotions, and the whole person became more and more irritable and sensitive. My husband asked the reproductive medicine department of Hebei Reproductive and Obstetrics and Gynecology Hospital after asking for advice from people around us. We work and live in Heilongjiang, too far away from Hebei. After careful discussion and research, we embarked on our journey to Shijiazhuang. Looking for a miracle thousands of miles away. In August 2019, we came to the first consultation of the Department of Reproductive Medicine. I looked for Director Yang Weimin of the Department of Reproductive Medicine. Director Yang carefully checked the existing case information in my hand and gave me the IVF with a superior plan. During the treatment, the process of promoting the discharge was very smooth. 14 eggs were obtained, 9 frozen blastocysts and 2 embryos in cleavage stage. In October, I used a hormone replacement cycle for FET (frozen embryo transfer). The thickness of the endometrium was 8.3mm. Two blastocysts were transplanted five days after the endometrium was transferred. The transplantation ended successfully, but the result was not pregnant. In November, my husband and I returned to the reproductive department for hysteroscopy, and the results showed endometritis. After giving symptomatic treatment, I had a second transplant. Given that I had not been pregnant with high-quality blastocysts before, I might consider For the problem of planting windows, the second transplantation uses sequential transplantation. After the transplant was successfully completed, I was in a hurry to wait for the result. Due to the epidemic situation, my husband and I returned to Heilongjiang and were unable to return to the clinic for the normal time. In order to facilitate my follow-up and medication, I joined the Leren Eugenics “Good Pregnancy Exchange Group”. Once I have any questions, the chief expert will Here I will give you a reply and guide me to use drugs, and also mail me the required drugs on time. We are very considerate to patients from other places. After the epidemic eased slightly, my husband and I went to the hospital for a pregnancy test HCG1357.5Miu/ml to confirm the pregnancy. I still felt unreal. I can’t believe that transplanting a 28-day color Doppler ultrasound showed double pregnancy sacs, and fetal heart buds were visible. Now that I have graduated from NT, I look forward to the arrival of the baby at home! Love and service will not be absent on the road of pregnancy, we will accompany you all the way!

The intima is getting thinner? The culprits are here!

Successful pregnancy must have two conditions: a well-developed embryo and a well-tolerated endometrium. Thin endometrium is one of the reasons for the failure to cancel the transplantation and embryo implantation in the IVF cycle. Thin endometrium currently still has no definite diagnostic criteria. It is generally accepted that the thickness of the endometrium measured by ultrasound during embryo transfer is ≤7mm, which can be called a thin endometrium. If the thickness of the intima is less than 6mm, the success rate of pregnancy shows a significant downward trend. Research on the age of the culprit of endometrial thinning has shown that the thickness of the endometrium is negatively correlated with the age factor, the estrogen receptor of the endometrium decreases with age, and the degree of endometrial stromal vascular sclerosis increases. Increased glandular apoptosis leads to a decrease in endometrial blood supply. It is still a bit difficult for senior women who are pregnant and difficult to get pregnant, their age is there. Be sure to grasp your best reproductive age! Repeated intrauterine operation repeated intrauterine operation damages the endometrium. In severe cases, endometrial repair disorders often lead to thin endometrium or intrauterine adhesions. Clomiphene is a first-line drug for ovulation induced by polycystic ovary syndrome. However, due to its antagonistic effect on estrogen and relatively long half-life, it often causes the problem of thin endometrium in the ovulation cycle. External factors Long-term (≥5 years) taking compound oral contraceptives will cause the endometrium to be stimulated for a long time, which will lead to limited endometrial growth and may reduce the success rate of embryo transfer. Primary hypertension, diabetes, smoking, drinking, and underweight are all related to the thin endometrium. A considerable number of patients with genetic abnormalities manifested as unexplained endometrial reactions. Their hysteroscopy showed normal uterine cavity shape, no scar adhesions and tuberculosis lesions, and only showed thin endometrium. Some patients even had no previous uterine cavity. Internal operation history. The endometrium is one of the factors that affect pregnancy, but it is not the only decisive factor. A strong embryo may still get the opportunity to implant and grow. We can “treatment” while trying and assisting pregnancy, waiting for the opportunity.

What are the causes of ectopic pregnancy

An abnormal pregnancy process in which a pregnant egg implants and develops outside the uterine cavity. Also known as “ectopic pregnancy”. Tubal pregnancy is most common. The cause is often due to inflammation of the lumen of the fallopian tube, which causes poor lumen patency, impedes the normal operation of the pregnant egg, and causes it to stay, implant, and develop in the fallopian tube, causing abortion or rupture of the fallopian tube pregnancy. Before abortion or rupture, there are often no obvious symptoms, and there may also be menopause, abdominal pain, and a small amount of vaginal bleeding. After the rupture, it showed acute severe abdominal pain, repeated attacks, vaginal bleeding, and even shock. Examination often has signs of intra-abdominal hemorrhage and masses next to the uterus. Ultrasonography can help. The treatment is mainly surgery, and the shock is corrected while the laparotomy is explored to remove the fallopian tube on the diseased side. If you want to preserve fertility, you can also open the fallopian tube to remove the pregnant egg.   1. Tubal inflammation   can be divided into tubal mucositis and peritubular inflammation, both of which are common causes of tubal pregnancy. Severe fallopian tube mucositis can cause complete obstruction of the lumen and cause infertility. In mild cases, the fallopian tube mucosa adhesion and cilia defects can affect the operation of the fertilized egg and be implanted there. Salpingitis caused by gonococcal and chlamydia trachomatis often involves the mucosa, and infection after abortion or childbirth often causes inflammation of the fallopian tubes. 2. Fallopian tube surgery If fallopian tube recanalization or fistula is formed after fallopian tube sterilization, it may lead to fallopian tube pregnancy, especially laparoscopic electrocoagulation fallopian tube sterilization and silicone ring sleeve surgery. I have undergone fallopian tube separation adhesion and fallopian tube because of infertility Plastic surgery, such as fallopian tube anastomosis, fallopian tube opening surgery, etc., the incidence of fallopian tube pregnancy is 10% to 20%.   3. Fallopian tube dysplasia or abnormal function    Fallopian tube dysplasia is usually manifested as too long fallopian tube, poor muscle development, and lack of mucosal cilia. Others include double fallopian tubes, diverticulum, or para-umbrellas, which can be the cause of fallopian tube pregnancy. If the secretion of estrogen and progesterone is abnormal, it can affect the normal operation of fertilized eggs. In addition, mental factors can also cause tubal spasm and motility abnormalities, interfere with the delivery of fertilized eggs.    4. Fertilized egg migration    The egg is fertilized in one side of the fallopian tube, and the fertilized egg enters the contralateral fallopian tube through the uterine cavity or abdominal cavity, which is called the fertilized egg migration. If the migration time is too long, the development of fertilized eggs increases, and the fallopian tube pregnancy can be implanted in the contralateral fallopian tube. 5. Assisted reproductive technology from the earliest artificial insemination to the application of commonly used ovulation promoting drugs, as well as in vitro fertilization-embryo transfer (1VF-ET) or gamete intrafallopian transfer (GIFT), etc., ectopic pregnancy occurs, and the incidence It is about 5%, which is higher than the general cause of ectopic pregnancy. The related susceptible factors include preoperative fallopian tube lesions, history of pelvic surgery, technical factors for embryo transfer, quantity and quality of implanted embryos, hormone environment, and excessive transplant fluid during embryo transfer.  6. ​​Other    Fallopian tubes due to the compression of surrounding tumors, such as uterine fibroids or ovarian tumors, especially the adhesion of the fallopian tubes and the tissues around the ovaries caused by endometriosis, can also affect the smoothness of the fallopian tube lumen, and hinder the operation of the fertilized egg. Some studies also believe that the defects of the embryo itself, abortion, smoking, etc. are also related to the incidence of ectopic pregnancy.

Elderly leukemia may try microtransplantation

In general, the complete remission rate of elderly acute myeloid leukemia is only about 30% to 50%, and the two-year survival rate is less than 12%. As we all know, hematopoietic stem cell transplantation is the only way to cure leukemia and achieve clinical cure. But for a long time, elderly patients with acute myeloid leukemia who are over 60 years old in the hospital have not been given hematopoietic stem cell transplantation. Why? The first is that donors are hard to find. Whether it is “full coincidence” (only identical twins are 100%, and there is no blood relationship, the probability of complete coincidence is only 1 in 100,000) or “half coincidence” (parents, siblings, children, even The cousin of the patient or the patient’s parents may become the donor), and there are still many people who cannot find a suitable match. In addition, the elderly patients with acute myeloid leukemia are over 60 years old, and their physical condition cannot withstand the destructiveness caused by general hematopoietic stem cell transplantation. Therefore, this kind of elderly patients can consider microtransplantation treatment, which is a hematopoietic stem cell transplantation in the “inconsistent” state, that is, anyone can become a donor. And on the basis of keeping the immune status of the recipient as much as possible, the micro-chimerization of bone marrow is carried out, that is, a large number of bone marrow cells are recipients, and the donor is only less than 1%. At the same time, microtransplantation also cooperates with chemotherapy and immune targeted therapy, with a treatment interval of two to three months, and the entire treatment is completed for about one year. The treatment of leukemia from the initial simple chemotherapy to myeloablative transplantation, non-myeloablative transplantation, and today’s microtransplantation, has experienced from the treatment dose and intensity and toxic and side effects from small to large, and then to greater, until the effect is guaranteed Under the premise of reducing the intensity and toxicity of the process. In the past four years, the complete remission rate of 70 elderly acute myeloid leukemia after microtransplantation was 80%, and the early mortality rate was only 6.7%. This clinical result has been clinically verified in many centers in China, the United States, Australia and Spain.

How long can the effect of autologous fat breast enhancement last?

Plump, tall, healthy breasts are an interpretation of feminine beauty. Now many beauty seekers are not very satisfied with their breasts, and after various methods such as diet and massage, the effect is very small. Fortunately, with the popularity of autologous fat breast surgery, more and more beauty seekers do autologous Fat filling increases your breasts and makes your body more sexy and slim. Of course, before the operation of autologous fat breast enhancement, there are still many beauty seekers who are more concerned about how long the effect of autologous fat breast enhancement can maintain. So, let’s discuss this problem together! Let’s do autologous fat breast enlargement surgery. The reason why it can improve breast weight loss is to suck out the right amount with a thin needle at the fat, waist, buttocks, legs, etc. The fat cells, after activation treatment, extract pure fat particles, which are evenly injected into the breast augmentation area through a micro tube needle to make it live. The breast enhancement effect is real and natural, and at the same time it has the effect of slimming. How long can the effect of autologous fat breast enhancement last? The duration of the effect of autologous fat breast enlargement actually depends on the survival rate of body fat injected into the beauty seeker and the technical level of breast enhancement experts. The beauty condition of the beauty seeker is particularly important here. It can be said from two large pieces: 1) Like women with plump subcutaneous fat, the fat particles sucked out are often bright yellow, bright in color, and the integrity and activity of the fat particles are also high; If the person who seeks beauty is thin, the fat content is low, the fiber content of the fat particles is high, and the triglyceride content of the fat particles is low, and the color is white, then the activity will be worse. 2) The skin tissue foundation is good: the facial subcutaneous tissue of the person seeking beauty is like transplanted soil. If a beauty seeker has thinner facial soft tissues and poor blood flow, the ability to nourish fat particles from other parts of the body is also relatively weak; while a beauty seeker with a rosy facial skin, thicker subcutaneous tissue, and full elasticity, compared with the former The ability to preserve transplanted fat particles will be stronger. The technical level of the second breast enhancement doctor should be properly transplanted. The principle of transplantation is to allow the fat particles to have the “largest” contact area with their own tissues. For doctors, in every detail of fat transplantation, protecting the activity of fat particles and “maximizing” the area of ​​the graft and the recipient area are effective means to improve the survival rate of fat transplantation. When these conditions are OK, generally speaking, after the autologous fat cells are injected into the chest of the beauty seeker, the fat cells survive and there is no obvious change in body weight. The effect of breast enhancement can be sustained in the body tissues for a long time. Of course! Affected by some aging factors, after a few years or more than a decade of autologous fat breast enhancement, the fat cells in the chest shrink and lose, and the effect of breast enhancement will weaken or even disappear. In this regard, after the beauty seekers complete the self-fat breast enhancement, they should pay attention to strengthening the maintenance of the chest, delay the aging rate of the chest, and make the effect of the self-fat breast enhancement last longer. Care after transplantation In addition, careful maintenance after autologous fat filling surgery will also affect the effect of transplant filling to a certain extent. After doing autologous fat breast enhancement, you should pay more attention to your diet if you want better results. For example: pay attention to avoiding the taste, do not eat spicy, stimulating food during the recovery period, eat more foods rich in vitamin nutrition, protein nutrition, fatty acid nutrition, so that fat cells survive better in the chest and chest. In addition, do not touch alcohol and tobacco during recovery. In fact, any surgery can not do without careful postoperative care. If you want to be beautiful, you must be responsible for yourself! Warm reminder: Autologous fat surgery is not simply extraction and injection. Many complications such as ineffective after injection and serious infections are mostly caused by key technologies. So if you want to choose this operation, you must choose the hospital and the surgeon carefully!

Shi Shurong Medical Talk: Can bone marrow transplantation prevent aplastic anemia from recurring?

The risk of aplastic anemia is very high, especially for severe aplastic anemia, and it is necessary to take active therapeutic measures immediately to control the symptoms of the disease and to avoid further development and deterioration. However, after treatment by various methods, many patients still suffer from repeated illnesses, and they have not healed for many years. Therefore, many patients hope for bone marrow transplantation. Director Shi Shurong’s WeChat signal zkxk9999 So, can bone marrow transplantation cure any obstacles? Can bone marrow transplantation prevent aplastic anemia from recurring? In fact, bone marrow transplantation is often a last resort for patients. Patients with milder or chronic aplastic anemia will not be treated with bone marrow transplantation. Most of them are controlled by drugs. Only when the condition is quite serious and other treatment options are not effective. The doctor would recommend considering a bone marrow transplant. With the continuous development and completion of bone marrow transplantation technology, patients who successfully cure aplastic anemia through bone marrow transplantation are not without them. However, patients with aplastic anemia who want to undergo bone marrow transplantation still need to “cross five obstacles”. First of all, whether the patient is suitable for bone marrow transplantation conditions, in addition to the severity of the disease, you also need to consider the patient’s ability to bear, too old or too young, not suitable for bone marrow transplantation. At the same time, aplastic patients have many In the history of blood transfusion, some patients even rely on blood transfusion to maintain life for a long time. In this case, there is a high probability of rejection after bone marrow transplantation, which is not suitable for transplantation treatment. Secondly, the difficulty of matching at present, most patients with aplastic anemia suitable for bone marrow transplantation treatment are single-child families, and the waiting time of the bone marrow bank is long, and the possibility of finding a fully compatible bone marrow donor in a short time is very small. Reduced the success rate of bone marrow transplantation treatment. Furthermore, the cost of aplastic anemia is relatively long, ranging from half a year to more than three to five years. Long-term treatment makes the family economically overburdened. At this time, bone marrow transplantation is a common choice for ordinary families. Ten thousand transplantation and related costs are really difficult to pay. At the same time, the chance of infection after surgery is also very high, once the infection is serious, there is also the possibility of “two people and money”. It can be seen that bone marrow transplantation does not guarantee that aplastic anemia will not recur, but infection, rejection, etc. may occur, leading to a more serious condition. Therefore, patients and their families should choose carefully for transplantation. For the treatment of aplastic anemia, it is recommended to use integrated traditional Chinese and western medicine treatment as early as possible, treat the syndromes differently, and treat the symptoms according to the symptoms. At the same time, combined with Western medical diagnosis and treatment, the bone marrow hematopoietic microenvironment is gradually improved to restore the normal hematopoietic function. ! For more aplastic disease knowledge or patient help, you can follow the WeChat public account: skg120

Before and after transplantation of leukemia patients, we should do daily preventive care!

For leukemia patients who are about to undergo transplantation and after transplantation, care and prevention in daily life need to be done. The patient’s self-care should start from four aspects. Before and after transplantation of leukemia, we must start from four aspects of hygiene habits: Leukemia patients need to wash their hands before and after transplantation, especially before and after meals. In addition, if the patient takes a bath frequently, it is also helpful to reduce the bacteria on the skin. Oral care: Radiotherapy and chemotherapy in the leukemia bone marrow transplantation pretreatment program make the tissues in the oral cavity very fragile. Good oral care can reduce oral infections and gum bleeding. Because it is recommended that patients should rinse their mouths frequently to keep the mouth clean. Exercise: Leukemia patients feel very weak during transplantation and are reluctant to exercise, but proper exercise can improve their physical and mental state. It is recommended that patients do not need to do vigorous exercise, and even exercise on their own beds, move their limbs, and walk out of bed. Supplemental nutrition: before and after transplantation, especially the pre-treatment stage before transplantation, usually affects the appetite and digestive function of leukemia patients. Due to changes in taste, nausea, dry mouth, etc., eating may become more difficult. Doctors can provide patients with sufficient calories and nutrition through intravenous infusion. However, in order to maintain the function of the digestive tract, it is recommended that patients insist on eating a small amount. Bone marrow transplantation is a battle. The transplantation stage is very important. It is related to the cure rate and survival issues. In addition to the main treatment preparation, patients also need to pay attention to daily care and preventive measures. Only with good disease resistance can we expect to get good treatment effects! If you have any questions about this article or the disease, you are welcome to follow us on WeChat Soyisou to learn more: dxbby120

How much dose should be injected for breast augmentation

Usually, an injection is about 200-300ml, which varies from person to person. The survival capacity of transplanted fat is limited. If a large amount of fat is transplanted to the breast at one time, although the chest can achieve fullness in a short period of time after surgery, as time goes on, part of the fat will appear ischemic necrosis and be absorbed by the body. During the injection process, induration may occur when there is no better grasp of the injection speed and the injected dose, and some patients need to be removed by surgery. After fat transplantation, the surrounding blood vessels provide nutrition and survive. The more fat that is filled, the greater the pressure on vascular feeding. For example, there are only 10 bowls of rice on the table, 10 people eat just right, but if 20 people eat only half full, 30 people will suffer Hungry…the more people there are, the fewer meals you eat, and the worse your physique. Fat filling is the reason. If the fat filling has such a situation of “more monks and less porridge”, the fat that is not absorbed by nutrients is difficult to survive, increasing the risk of lumps and fat sacs caused by liquefaction, calcification, and fibrosis. Therefore, there is a certain limit to the amount of fat transplantation. It is not as much as you want. The doctor will control it based on personal basis, clinical experience and safe range. If the breast is fat, generally it can be increased by 1-1.5 cups .

With regard to fat filling, your concerns are all here!

“Can one-time filling achieve the expected effect”, “What will happen if it can’t be reached?”, “Why do some people fill the same as no filling”, “Can you guarantee 100% survival rate”, ” “How to improve the survival rate of fat transplantation”…… It is simply one hundred thousand why! All you want to know about fat filling is here! Q&amp.A Can one-time fill achieve the desired effect? Dr. Yang Mingqiang: Not necessarily, the final effect varies from person to person, depending on the survival rate of fat. The survival rate of the transplanted fat is high, and the expected effect can be achieved by one filling. If the survival rate is low, the one-time filling cannot achieve the expected effect. Q&amp.A What should I do if one filling fails to achieve the expected results? Dr. Yang Mingqiang: If the survival rate of fat filling once is relatively low and the expected effect cannot be achieved after surgery, you can perform two or three fillings until the effect is satisfactory. Q&amp.A Why do some people fill in the same as not fill in? Dr. Yang Mingqiang: Because the fat filled in does not survive, the fat filled in is completely absorbed by the body, so filling it is the same as not filling it. Can the fat filled in Q&amp.A guarantee 100% survival? Dr. Yang Mingqiang: No, there are many factors that affect the survival of fat. Each factor does not ensure 100% support, so the survival rate of fat cannot reach 100%. Q&amp.A&nbsp.Nature how does honeycomb fat transplantation improve the survival rate of fat? Dr. Yang Mingqiang: The fat survival rate is the probability that the fat survives after being transplanted to the designated site. After the transplanted fat is completely stabilized, the fat will be completely survived and will no longer be absorbed by the body. This complete survival time is generally after surgery About 1-3 months. In addition to the fact that we cannot control the survival rate of fat, the doctor can strictly grasp the fat removal and transplantation. Nature honeycomb fat transplantation uses low negative pressure suction, low speed centrifugation, and low volume injection to reduce the damage to fat cells. In terms of fat extraction, abdominal fat is preferred, fresh high-density fat, fat gum and AMC with strong support and long-lasting shaping effect are extracted. Nature’s aesthetic principles The key to Nature’s honeycomb fat transplantation lies in the reconstruction of the youthful state of the face. It innovatively proposes three principles of Nature’s aesthetics: left-right symmetry, harmonious proportions, and smooth curves. While pursuing soft facial sculptures, more attention is paid to the harmonious and symmetrical facial features, natural and vivid expression, and clear and smooth curves, which are more in line with oriental aesthetic facial standards. &nbsp.

Autologous fat breast augmentation

Autologous fat transplantation breast augmentation technology is to use the characteristics of women’s waist, abdomen, buttocks, legs and other parts of the fat is relatively rich, the medical book records that the fat particles of these parts are transplanted to the chest. The operation will suck out the excess fat of the breast augmentation person with a fine needle, and specially activate the treatment into pure fat particles, which will be evenly injected into the breast augmentation area in layers through a micro tube needle to make it alive. No surgery and no bleeding, the breast enhancement effect is real and natural, and at the same time, the effect of weight loss and body shaping is achieved. General autologous fat shaping may require two times, and in rare cases may require three operations. This is because fat may be absorbed after being transplanted to the designated site. However, through advanced surgical technology, the survival rate of fat particles is high, and the method of appropriately increasing the total amount of fat implantation can be formed in one operation. However, individual cases (due to personal constitution and other circumstances) require more than one operation.

How to improve fat survival rate with autologous fat filling?

How to improve fat survival rate with autologous fat filling? Compared with the aesthetics of European and American countries, the aesthetics of our entire Asian region still prefer young and energetic young cuties. Therefore, the fullness of the face is an important aspect for beauty seekers who want to change their face. The advantage of self-fat filling is that it is not afraid of rejection, and can also be slimmed down at the same time. It is very popular with the beauty seekers. Before this operation, the person who asked the beauty asked me the most question is how can I improve the fat survival rate? Before answering the previous question, let me share with you again what is autologous fat filling? Autologous fat filling, as the name implies, the fat is taken from the body of the person who seeks beauty, and after a series of special treatments, it is transplanted to the desired part. The advantage is that it is permanent after survival, and there are no hidden dangers such as rejection infection. The fat that has been used in your stomach and thighs for many years is not likely to cause you to have an allergic reaction. During this operation, many people think that I can survive as much fat as I can, but this is not the case. Let me give you an example like a leafy plant. It is possible to move from one flower pot to another. Like withering, the transplanted fat cells need to find blood supply in the new home, otherwise the fat cells will die or be absorbed by the body. So, this is a fierce competition with time. The transplanted fat needs to be re-connected to the blood supply within a few days after transplantation to be truly alive. Therefore, the postoperative fat survival rate is also closely related to the physical state of the person seeking beauty. In addition to your own physical condition, what other ways to improve fat survival rate? Secondly, it is really time to test the skills of doctors. Although there are many so-called new technologies, the key to ultimately affecting the survival rate of fat transplantation lies in the skills of doctors. I have already mentioned the problem of fat activity. In fact, in addition to the fat conditions of the beauty seeker itself will affect the fat activity, the doctor’s liposuction technology and the selected purification process will also affect the activity of the fat particles. In every detail of fat transplantation, protecting the activity of fat particles and maximizing the transplanted area in the filled area are effective means to improve the survival rate of fat transplantation. Here, the operating doctor must be able to accurately grasp the anatomical level of the human face, the distribution of blood vessels and facial muscles, and be familiar with the functional division of the surgical site. They know what method should be used to inject fat particles into which position and at what level can they be maximized The survival rate of fat particles. Taking the forehead as an example, it is more difficult to fill the forehead with fat (the soft tissue of the forehead is thin and compact), and it is easy to form unevenness. The experienced doctor will inject the fat evenly under the skin, under the frontal muscles, and on the periosteum. Need to press flat with hands (compression will affect the survival rate of fat). For areas with relatively low survival rates, such as temples, some doctors will take over-filling and higher-viscosity fats (separate preparation of temple-filled fats) to solve. Of course, postoperative care is also very important. After doing autologous fat filling, pay attention to the following points: do not drink and smoke, eat spicy and stimulating food, do not lose weight, and do not make dramatic exaggerated expressions within 3 months after the operation to prevent squeezing Freshly filled fat. &nbsp.&nbsp.&nbsp.&nbsp. In this fat-filled trip, those surviving fat cells can stay with you for a lifetime. &nbsp.