Xiebeilu Studio WeChat add369456 article source: transferred from WeChat public account [Xiebeilu Studio] As the name implies, purpura symptoms caused by allergies. So this is a vascular allergic disease. The body is allergic to certain substances and can’t take it anymore. The blood vessels inside the body protest and become brittle. The blood can leak out. The skin is just those “purpura”. This is still Mild, those with visceral bleeding that do not appear on the skin must be more troublesome. If one day suddenly finds some blemish purple spots on the skin, then you need to go to the hospital in time to check, because the body bruise will appear like this, but the symptoms of allergic purpura. Bruising will dissipate on its own after a few days, so for patients with purpura, can this symptom disappear on its own? How high is its self-healing? Allergic purpura generally does not have its own good possibility, only It can be said to be transient. It is common to see that purpura resolves on its own in a short period of time, and it is small in size. It will not cause recurrence or recurrence of purpura due to external factors such as colds, fever, increased activity, and dietary problems. I found allergens far away from it, which of course has very very great benefits for the treatment of diseases, but this allergen is not easy to find, because there are too many factors that can sensitize, food is possible, drugs are also possible, and infections are also As for pollen and the like, there are countless of these categories, so it is very difficult to find allergens, and there may not be much gain. Although allergic purpura is a self-limiting disease, the prognosis is good; but still be careful, do not do some bad measures such as staying up late or overeating! At this time, it is recommended to follow up and observe, and diet and activity levels need to be restored to a reasonable and normal level.
In the group of patients with immune thrombocytopenic purpura, there are many children. For the conventional hormone therapy of this disease, some side effects are inevitable, so many parents of children worry that hormone drugs will affect the growth of their children. Director Shi Shurong’s WeChat consultation platform: zkxk9999 Sichuan Ms. Li Consultation: The child is six years old this year. Immune thrombocytopenic purpura diagnosed last year. Recently, he is still taking hormone therapy. The platelet will increase when the hormone drug is used. Repeated phenomenon. However, long-term use of hormones, recently found that children are overweight, very worried that long-term use of hormones is harmful to the body. So, can hormones be used for a long time? Hematology expert director: Immune thrombocytopenic purpura is the most common hemorrhagic disease in children. Hormone and globulin therapy are generally effective, but some children’s platelet count is prone to repeated decline, so if you use hormones, you must regularly follow up, adjust regularly, reduce the amount in time, pay attention to avoid upper respiratory tract infections, etc., you can assist in the application of other drugs, etc. . Some parents of children are afraid of side effects of hormones, and stop taking drugs or reducing the amount of their own, but it is easy to cause the hormone application time to be prolonged, and the condition is not easy to control. Therefore, the use of hormonal drugs to treat thrombocytopenia needs to follow the doctor’s instructions, and should not be stopped by themselves. At the same time, hormonal drugs will produce some side effects. It is recommended to add targeted Chinese medicine as soon as possible to reduce the side effects, effectively improve the efficacy of the drug, stabilize the platelet value, and avoid repeated attacks. More patient communication help can pay attention to the WeChat public account: [thrombocytopenia patient association] xxbjs75
Henoch-Schonlein purpura is usually acute, and some patients can achieve rehabilitation and withdrawal in a short period of time, and some will prolong the course of the disease, but the targeted treatment will not exceed too long. Yes! The symptoms of allergic purpura have completely disappeared, will it recur in the future? In many cases, the current symptoms have disappeared, and no new purpura has appeared. In this case, don’t take it lightly. Do not do some bad measures such as staying up late or overeating! At this time, it is recommended to follow up and observe, and diet and activity levels need to be restored to a reasonable and normal level. For example, before, there was a patient with allergic purpura, simple skin, and had a urine occult blood during this period. This patient did not dare to eat and exercise normally after stopping the medicine without symptoms, until an accident a few months later. After the incident happened, I walked a long way in anxiety. When I came back, I found that the calves were all densely purpura. This is a relapse (it is equivalent to a slingshot with a strong foot). The premise/standard for the complete cure of allergic purpura is: complete discontinuation of the drug, and all indicators are normal, whether it is immunology, blood routine or urine test, there are no external symptoms, no taboos, normal activity, follow-up for half a year to more than one year Relapse (the follow-up of a special disease group takes about two years) can be judged as rehabilitation. The disease will not relapse after a full recovery, and under normal circumstances, the longer the time, the lower the relapse rate. As for relapsed patients, it is necessary to determine whether there are susceptible factors in the body, the main reason is whether the previous treatment has been “rooted”. If you have any questions about this article or the disease, please feel free to follow us on WeChat Soyisou: gmxzd1
Comprehensive care of children with allergic purpura First, skin care of children with allergic purpura Observe the shape, number and location of the rash, whether it appears repeatedly, and draw a human figure to record the rash daily changes. If the rash is itchy, keep the skin clean, prevent abrasions, and prevent children from being scratched. If there is a rupture, treat it in time to prevent bleeding and infection. Wear soft, breathable, loose cotton underwear, and change it frequently to keep the bed. Clean, dry and free of debris, avoid using alkaline soap. Second, diet care of children with allergic purpura Allergic purpura do not eat allergenic food, if it is purpura caused by food allergies, you need to strictly ban this food for life. Common allergic substances, animal foods include fish, shrimp, eggs, milk, etc., and plant foods include broad beans, pineapples, plant buds, etc. Be careful not to use cooking utensils and utensils that come into contact with allergic substances. Eat more foods rich in vitamins C and K. Avoid spicy food. Pay attention to avoid eating food that is rough, hard, and mechanically irritating to the gastrointestinal tract. Children with renal purpura should be given a low-salt diet. Third, the symptoms of pediatric allergic purpura children with allergic purpura symptoms are mainly abdominal pain, diarrhea, vomiting, vomiting blood and blood in the stool. Children with abdominal pain should rest in bed and observe the complexion, expression, posture, and nature, location, degree, and duration of the pain, for any accompanying symptoms, such as nausea, vomiting, diarrhea, and bloody stools. When the child is vomiting, take a lateral position. After vomiting, remove the vomit in time to prevent suffocation, and observe and record the nature and amount of vomit. When there is gastrointestinal bleeding, you should rest in bed, limit diet, give no residue of liquid food, fasting when there is a lot of bleeding, and give blood transfusion and intravenous nutrition as directed by your doctor. 4. Psychological care for children with allergic purpura Do good psychological care, you can play beautiful music or tell stories for children, use some interesting toys to distract children from pain, and eliminate the fear of children and parents. Reduce their psychological burden, establish treatment confidence, and ensure the smooth progress of treatment.
Allergic purpura: Medically, it is called purpura because of the subcutaneous hemorrhage with a diameter of 3-5 mm. There are many causes of purpura, such as: allergic reactions, thrombocytopenia, and family inheritance. Allergic purpura is a common disease caused by allergic (allergic) reactions in the body. Allergic purpura begins to show skin and mucous membrane purpura, and has fever, headache, discomfort and loss of appetite. Occasionally, abdominal cramps or arthralgia are the main manifestations. The earliest skin appeared as small, scattered, petechial urticaria-like rashes, which generally became hemorrhagic in one day. Occurs in the extremities of the extremities and hips, showing symmetry. Renal damage occurs in about 50% of cases, from mild nephritis to severe renal failure. Henoch-Schonlein purpura can occur at any age, and is more common in children and adolescents. The incidence is higher in spring and autumn. etiology: ① bacteria, viruses and intestinal parasites; ② food; ③ drugs: sulfonamides, antipyretic analgesics, etc.; ④ other (insect bites, plant pollen, vaccination, etc.). What is allergic purpura nephritis: Allergic purpura is a systemic syndrome with small blood vessel damage as the main pathological basis, clinically characterized by skin purpura, hemorrhagic gastroenteritis, arthritis and renal damage. Since more than 1/3 of allergic purpura patients have kidney damage, the prognosis depends mainly on the severity of nephropathy, so the kidney damage caused by allergic purpura is called allergic purpuric nephritis. Occurrence: This disease often occurs in children under 10 years old, and is rare in adults (>.; 20 years old). It happened in the cold season. About one-third of patients have a history of infections with pioneers such as bacteria and viruses, but failed to prove a positive relationship with streptococcal infections. About 1/4 of the patients are related to fish or shrimp allergies or preventive injections and medicines. Most patients have a benign, self-limiting process, and most recover within a few weeks. However, there are also recurrent episodes or delays for months and years, and about 50% of patients have recurrent episodes. Regarding the incidence of allergic purpuric nephritis in allergic purpura, 2840 cases were reported, and 37.6% of them had purpuric nephritis. The cause of allergic purpura nephritis: Allergic purpura nephritis is a secondary disease of allergic purpura, and the cause of allergic purpura is not yet clear, and may be related to toxins and allergies. Some cases have infections before onset, the most common is upper respiratory tract infections (non-specific or streptococcal infections), others such as chlamydia, chickenpox and parasites. Many cases have allergy to toxins such as drugs (antibiotic, iodine, isoniazid, salicylate, barbiturate and iodide) or food (milk, fish, shrimp, crab and clam, etc.) before illness. is currently considered to be an immune complex disease. IgA plays an important role in the pathogenesis. The serum IgA of patients in the acute phase is significantly increased, and the affinity between IgA can produce high molecular weight aggregates. IgA immunofluorescence is positive in more than 90% of cases of glomeruli and skin small blood vessel walls. Patients with acute serum factor VIII activity in the acute phase and the presence of fibrin (progenin) in the glomeruli suggest that the coagulation mechanism is involved in the pathogenesis of this disease. Why does allergic purpura often cause allergic purpura nephritis? Because antigens produced by pathogenic factors combine with antibodies in the body to form immune complexes (IC), immune complexes are most likely to be deposited in the glomeruli and activate complement, resulting in neutrophil migration, chemotaxis and a series of The release of inflammatory mediators causes vascular inflammation, increased vascular fragility and permeability, leading to allergic purpura nephritis. Immune complex (IC) is most likely to be deposited in the glomerulus: ①The glomerular basement membrane is a filter plate, and the medium-sized IC is easy to be retained and embedded in the glomerular basement membrane; ②glomerular Endothelial cells have C3b receptors, and ICs containing complement are easy to bind to and deposit; ③ kidney blood flow is large, glomerular microvascular branches are many, blood vessels are thin and tortuous, and blood flow is slow, which is conducive to IC deposition.
Allergic purpura is mostly caused by allergies or ingestion of allergic foods. Allergic purpura is not easy to treat, and prevention should be the mainstay. Medicine believes that this disease is a disease that invades the body, damages the veins, and the menstrual blood overflows the skin and mucous membranes. The cause is to feel the evil, diet disorder, and blood stasis. Deficiency of qi and blood are the main causes. Clinically, there are many syndromes of yang and heat. If it is protracted, the recurrence will be manifested as a syndrome of deficiency and deficiency. Allergic purpura is the first to experience external evils, and it is caused by burns to the blood. Heat and blood are forced into blood. How to treat allergic purpura, there are the following methods of treatment: 1. Instrument treatment: many violations of the natural laws of metabolism, mandatory treatment of allergic purpura. Cause capillary damage, easy to relapse. 2. Chinese medicine treatment: is a medicine Three-point poisoning, the efficacy of traditional Chinese medicine is diverse, can not accurately define the effective active ingredients, lack of modern biological engineering technology, some Chinese medicine ingredients can also cause allergies. 3. Oral hormone therapy: only improve the symptoms of allergic purpura from the surface of the skin, Targeting is very simple, the symptoms are not cured. The irritant hormone directly contacts the skin. 4. External hormones: It can relieve the symptoms, but these drugs have large side effects and more dependence, and the symptoms will recur. Precautions 1. Prevention Allergic purpura should improve allergic constitution, often participate in physical exercise, enhance physical fitness, prevent colds and other diseases. 2. Actively remove infections, prevent upper respiratory tract infections, and prevent allergic purpura; control tonsillitis, dental caries, sinusitis, and intestinal parasites such as roundworms and hookworms. 3. To prevent allergic purpura caused by pollen season, people with allergies should pay attention to reduce going out; find out allergens as much as possible and avoid eating suspicious food and suspicious drugs. 4. To prevent allergic purpura caused by excessive fatigue; when the acute phase and the amount of bleeding are large, activities should be restricted and bed rest should be tried as much as possible. 5. The diet should be light. Foods rich in nutrients and vitamins can prevent allergic purpura. Avoid spicy and fatty taste. Non-smoking wine. 6. Keep the mouth and skin clean to prevent infection. Adjust your emotions and keep your mood relaxed and happy
Is allergic purpura serious? Allergic purpura is an allergic vasculitis that invades the small arteries and capillaries of the skin and other organs. It is often accompanied by abdominal pain, arthralgia, and kidney damage, but the platelet does not decrease. Allergic purpura may be related to streptococcal infection, viral infection, drugs, food, insect bites, etc. The mechanism of occurrence is due to immune complex deposition or IgE-mediated vascular damage. There have also been reports of increased IgA in the serum of patients, and IgA deposition in the skin small blood vessel walls and glomerular tissues in skin lesions and non-skin lesions. Occurs in children and adolescents, and may begin with fever, headache, joint pain, and general malaise. The lesions are characterized by petechiae, petechiae, or urticaria-like rash from the needle to the size of soybeans. In severe cases, blisters, blood blisters, and even ulcers may occur. Occurs in the extended sides of the limbs, especially the lower limbs and buttocks. The lesions are symmetrically distributed, appearing in batches and prone to relapse. Only those with skin damage are called pure purpura, and those with abdominal pain, diarrhea, blood in the stool, and even gastrointestinal bleeding are called gastrointestinal purpura; those with joint swelling, pain, and even joint effusion are called joint purpura; Hematuria, proteinuria, and renal damage are called renal purpura. Allergic purpura nephritis refers to renal damage caused by systemic diseases with allergic purpura with necrotizing small vasculitis as the main pathological change. Allergic purpura nephritis clinical manifestations in addition to skin purpura, joint swelling and pain, abdominal pain, blood in the stool, kidney involvement mainly manifests as hematuria and proteinuria, and some severe patients can cause impaired renal function. Kidney involvement usually occurs within days to weeks after skin purpura. Most of the joint symptoms of patients with purpuric nephritis are characterized by wandering multiple joint pain. Commonly affected joints are knees, ankles and hands. The most common gastrointestinal manifestations of patients with purpura nephritis are abdominal pain, accompanied by nausea, vomiting and bloody stools, and occasionally hematemesis. Purpuric nephritis in children can sometimes be complicated by intussusception, intestinal obstruction, and intestinal perforation. Henoch-Schonlein purpura is a blood vessel allergic hemorrhagic disease caused by the human body under the state of immune stimulating. It is a blood vessel caused by immune stress response and bleeding caused by increased brittleness, which can easily affect the gastrointestinal tract, joints, kidneys, and severe It is nephrotic syndrome, kidney failure, which is life-threatening. Allergic purpura can also cause hypertension, accounting for 20%-40% of patients with hypertension.
#诊间故事# . Fan question, female, 81 years old, rash on lower limbs, no pain, no itching, no symptoms, just want to ask what is the disease?  . . . . . .@微博健康医疗 . Purpura in the lower extremities is the bleeding point mentioned by the boss’s surname. There are many types of purpura. This 81-year-old woman is generally called senile purpura, also called tension purpura. The blood vessels of the elderly are relatively fragile, standing for a long time of compression, stimulating blood to penetrate under the skin from the blood vessels, and the common people also have bruises.  . . . . . . . .@爱问医生科普 . . In this case, we recommend that you come to the hospital for a face check, which can be used for blood tests, except for platelet reduction and other problems.  . . . . . . . .@爱问医生皮肤科 . The treatment is not very meaningful, most of it can be absorbed by itself after a while, of course, it may appear again and again. We recommend standing as little as possible, taking proper breaks, and combining work and rest. You can use some topical medicines, such as hi therapy, etc., to promote the absorption of ecchymosis.  . . . . . . . This situation is very common in the elderly, the limbs are obvious, especially the lower limbs. #名医服务月##夏健康指南#
The third issue of the allergic purpura symposium: the first allergic purpura occurred 9 years ago. What should I do if I eat some duck meat and pineapple and relapse? Consultation status: patient’s own age and sex: 31-year-old woman’s condition Question: I have been suffering from purple epilepsy since 11 years. I have seen several places. I have been hanging water for a month. I have been in the Chinese medicine hospital. It’s just like drinking soup. I checked in Linyi that the allergen is house dust allergy. In the past few years, I have eaten everything. It’s okay. Last year, I started to have a bad throat since summer. I always have inflammation. Because I sell clothes, I have to hit one or two months. The water can only be suppressed without pain. Until the end of the twelfth lunar eruption, and then I took the medicine for a few days, I started to hang the bottle for ten days, and it has no effect. I just took soup for a few days. Well, I didn’t get up for a few days. I didn’t know what the cause was a little bit midway, and then I started a few more. Until this time, I seemed to have eaten some duck meat and pineapple. Now I don’t move much, there will be a small rise, what should I do? —Must read—In order to better help each patient/family understand the disease and overcome the disease. To this end, set up the [Sick Questions Collection] channel. Regularly extract the questions mentioned by the patients for detailed answers. Due to different disease deviations, the answer cannot be generalized, and individualized guidance is needed. Follow the patient’s WeChat public account to get answers: xejb120
Hu Guisheng Assistant WeChat: dd326751 Article Source: Transferred from WeChat public account [Hu Guisheng Studio] Stomach pain caused by allergic purpura is a very common disease, this disease will not only affect the patient’s skin, but also cause kidney disease and joints Diseases require patients to receive timely treatment. Henoch-Schonlein purpura can cause hematuria, and the patient is accompanied by symptoms such as nausea and vomiting, skin pimples, etc., and joint movement is inconvenient, you can come to understand its symptoms. Allergic purpura is a spontaneous disease, but it is also very harmful to the human body. It is actually different from ordinary skin allergies. This disease not only hurts the skin of the patient, but may also cause arthritis or other Kidney disease. Patients must be highly valued. Below we will introduce you to the symptoms of allergic purpura. Abdominal pain, as we mentioned, most patients will present with colic. The symptoms of Henoch-Schonlein purpura are mainly caused by extravasation of blood into the wall of our intestine. The most common pain is the navel and right lower abdomen, and some can even cover the entire abdomen, but generally there is no abdominal muscle tension and tenderness is relatively light. The symptoms of allergic purpura can also be accompanied by nausea, vomiting, diarrhea, and dark stools. Irritation caused by intestinal wall bleeding can cause intestinal peristalsis, causing intestinal wall spasm and abdominal pain. If abdominal pain symptoms are prominent, or abdominal pain symptoms appear early and skin purpura appears late, then this type of allergic purpura is clinically called abdominal purpura. For abdominal purpura, if the symptoms are not controlled and relieved in time, there will be other complications besides abdominal pain, such as intestinal obstruction, intussusception, intestinal perforation, etc., which will increase the suffering of patients. Suspected abdominal purpura is not only about gastrointestinal reactions, but also needs to pay attention to the appearance of purpura on the external skin. It can be accompanied by stomach pain and subcutaneous purpura. Careful examination of the extremities is required to see if there are symmetrically distributed skin petechiae and bleeding Skin rash, ecchymosis, etc. In addition, for gastrointestinal manifestations and external subcutaneous purpura manifestations, a small proportion of purpura patients with initial abdominal pain are also accompanied by various symptoms, such as joint pain, abnormal urine test, etc., there are many types of symptoms, which can be directly judged as mixed Type purpura. Because of the risk of complication of the disease, it is necessary to seek medical treatment as soon as possible to relieve the symptoms.
Xiebeilu Studio WeChat add369456 article source: transferred from WeChat public account [Xiebeilu Studio] Many people will have bruises, and the main reason may be related to family genetic skin disease, purpura is related, if recently found bruises on the ankle The symptoms, be careful, may be related to inflammation, such as bumps or accidental bumps when exercising, and partial pressure by heavy objects, this time will cause bruising in the local blood circulation of the skin, so the body appears Bruising is looking for reasons. 1. Capillaries may be inherently fragile. Most people have bruises. The reason is related to family inheritance. Family inheritance of subcutaneous capillaries is relatively fragile. A slight external force will cause bruises on the body, but this is not healthy for the body. No need to worry about what impact. 2. It may be simple purpura. Simple purpura is generally more common in women’s menstrual period. During menstruation, women repeatedly have bleeding points or ecchymosis on the skin of the lower extremities and buttocks. They will not fade after pressing, which may be related to abnormal capillary wall. . Some patients have a positive beam arm test. This may be a situation that many people often appear, but simple purpura does not have much impact on people’s health. Generally, it is better to wait for its own good, and no special treatment is required. 3. It may be thrombocytopenia. Platelets are the main force responsible for clotting blood in our body. If it becomes less, the skin and organs of the human body are prone to bleeding. This bruise caused by thrombocytopenia is called thrombocytopenic purpura. Thrombocytopenia is very harmful to the human body, which can easily lead to repeated bleeding in the mouth and nose, increased menstrual flow, dizziness and headaches. In severe cases, there will be life-threatening conditions such as blood in the stool and gastrointestinal bleeding, so it must not be taken lightly.
Henoch-Schonlein purpura is one of the most common vasculitis in childhood. It was described by Xu Lan’s and Heng’s pressure in the 1830s and 1970s, so it is also known as Xu Lan-Heng Nuo’s vasculitis. The disease is the most common capillary allergic disease, based on a wide range of small blood vessel inflammation as the pathological basis, skin purpura, gastrointestinal mucosal bleeding, joint swelling and nephritis as its main clinical manifestations. Older children, especially school-age children, are more ill, with a minimum age of 3 months. The incidence is more in winter and spring and less in summer. Causes of various allergenic factors, including infections (bacteria, viruses, especially Coxsackie B virus, parasites, etc.), food (milk, eggs, fish, shrimp, etc.), drugs (antibiotics, sulfonamides, antipyretic and analgesic Agents, sedative drugs, etc.), pollen, insect bites, vaccination, etc. make allergic reactions of the body with sensitive qualities, produce self-antigens, and then produce the corresponding antibodies, forming antigen-antibody complexes, calming the small blood vessel walls of the body, Causes pathological changes mainly caused by vasculitis. Therefore, the disease is an autoimmune disease. 2Clinical manifestations The onset can be acute or slow, and most of them are acute. Most children have a history of upper respiratory tract infection 1 to 3 weeks before the onset. There may be irregular hypothermia, fatigue, headaches and other non-specific manifestations. 1. Skin symptoms The rash is the main manifestation of the disease, which is more common in the lower extremities and dense around the ankle joints. Secondly, it can occur on the buttocks and upper extremities, and the trunk is rare. The shape and color of the rash may vary. At first it was small urticaria or pink maculopapular rash, which faded. Then the color deepens and erythema forms. Spotted bleeding occurs in the center of the erythema, and the color changes from pink to dark purple, which is purpura. Purpura can be fused into tablets. Finally, the color turned brown and faded, leaving no trace. In addition, there are erythema multiforme and erythema nodosum. Angioedema can be seen in the head, eyelids, lips, hands, feet, kidneys, and perineum. Sometimes the swelling can be tender. 2. Digestive tract symptoms are relatively common and can be seen in two-thirds of children, clinically known as abdominal type. Abdominal pain is the most common, mostly severe colic, which occurs around the umbilical cord and can also be found in other parts. Three quarters of children may have tenderness. There may also be vomiting. Then bloody stools can be seen, and severe cases are bloody stools. Hematemesis is rare. It is often easy to misdiagnose as acute diarrhea, especially before the rash appears, and there are not many people who undergo laparotomy for this reason. A small number of patients may be complicated by intussusception, occasionally intestinal obstruction, perforation, and hemorrhagic necrotizing enteritis. 3. Joint symptoms About half of the children may have multiple arthralgia or arthritis, which are more common in the lower limbs. Swelling and pain are more pronounced in those with rashes around the joint. Clinically referred to as “articular type”. The fluid in the joint cavity is mostly serous. Joint symptoms usually disappear within a few days, leaving no deformation. 4. Kidney symptoms About one-third of children have nephritis. The younger they are, the more they develop. It can be gross hematuria or microscopic hematuria. It usually occurs 2 to 4 weeks after purpura, and can also appear after the rash subsides or the disease is still. Clinically known as “kidney type”. The severity of the disease varies, and most of them are severe. In severe cases, renal dysfunction, azotemia, and hypertensive encephalopathy can occur. In a few cases, hematuria, proteinuria, or hypertension may last more than 2 years. 5. Other mixed cases may have central nervous system symptoms, such as coma, optic neuritis, subarachnoid hemorrhage, Guillain-Barre syndrome, individual limb convulsions. 75% of the children had abnormal EEG, and the EEG returned to normal within 6-20 months. Severe cases can cause temporary abnormalities in electrocardiogram due to myocardial hypoxia and ischemia. Occasional reports of acute pancreatitis, orchitis, and pulmonary hemorrhage. 3 Examination There is no specific laboratory test for this disease. Anemia can be shown when the amount of bleeding is large. Leukocytes are moderately elevated, eosinophils are normal or elevated, platelets are normal, bleeding time, clotting time, and blood clot contraction are normal. Erythrocyte sedimentation rate increases, C-reactive protein and anti-streptococcal hemolysin may be negative. Pharyngeal culture showed β-hemolytic streptococcus group A. Serum IgA increased slightly. You can understand the condition of kidney, brain and heart by urine test, electroencephalogram and electrocardiogram. The fecal occult blood test was used to monitor gastrointestinal bleeding. Renal tissue biopsy can determine the nature of nephritis lesions, and has guiding significance for treatment and prognosis. 4Diagnosis Because skin lesions are usually typical, acute abdominal pain, arthralgia and urine changes are also helpful for diagnosis. Allergy developed by the American Rheumatology Association in 1990
Purpura is a general term for purpura to change color after bleeding from the skin and mucous membranes. The clinical manifestations are bleeding points, purpura, and ecchymosis. They generally do not rise above the skin surface. They can only swell slightly in purpura. They begin to be purplish red, and the pressure does not fade, and then gradually become lighter. After about two weeks, they turn yellow and disappear. Purpura is the most common clinical manifestation of hemorrhagic diseases. Once purpura is found, the following possibilities are suggested: ① Vascular purpura. Very common, due to damage to the blood vessel wall or its increased fragility and permeability, common in immune (such as allergic purpura), infectious (such as sepsis), abnormal blood vessel structure (such as hereditary hemorrhagic capillaries) Expansion) and other (such as abnormal proteinemia, simple or senile purpura, etc.) diseases. Except that the beam arm test may be positive, there are no other abnormalities. ② Platelet abnormal purpura. The most common, mostly due to thrombocytopenia, increased and abnormal function, if purpura or blood blisters in the oral and buccal mucosa, often indicate severe bleeding, should be actively managed. ③ Impairment of blood coagulation mechanism, including lack of blood coagulation factor, circulating anticoagulant substance or fibrinolysis, generally speaking, bleeding caused by blood coagulation disorder, mainly manifested as joint hemorrhage, muscle hematoma and visceral hemorrhage, less skin purpura , Only occasionally manifested as large ecchymosis, and check the blood coagulation for obvious abnormalities, which can be distinguished from purpura caused by vascular purpura and platelet abnormalities. The treatment of purpura varies depending on the cause. The causes of purpura hemorrhage can be classified into two categories: (1) Vascular system lesions due to lesions of the blood vessel itself, such as damage to the blood vessel wall or increased permeability and fragility of the blood vessel wall, causing leakage of red blood cells in the blood to form purpura. Vascular damage can be caused by bacterial toxins, chemical drugs, and vitamin deficiencies. Such as simple purpura, allergic purpura, purpura with increased intravascular pressure. (2) Hemorrhage due to disorders of blood system coagulation function. Such as thrombocytopenic purpura, fibrinogen-reducing purpura, prothrombin-reducing purpura caused by liver disease, and purpura caused by the application of too many anticoagulant drugs. The above-mentioned diseases not only cause bleeding of the skin, but also cause bleeding of other tissues and internal organs. If you have purpura, you can’t just think of it as bleeding. You should carefully check the organs of each system to exclude blood system diseases. There are some special types of purpura, such as rheumatoid purpura, thrombotic purpura, etc., all need to go through a systematic inspection to find out the cause and disease. Therefore, purpura should not be taken lightly. There are many ways to classify purpura, which can be divided into thrombocytopenic purpura and non-thrombocytopenic purpura according to general habits. Some people are divided into inflammatory purpura and non-inflammatory purpura according to changes in blood vessel walls. Others are classified according to etiology and clinical manifestations. Common purpura and classification are as follows: According to the cause of the patient’s disease, there are three main types: (1) The cause of simple purpura is not clear, the general incidence is mild, there is no obvious blood and blood vessel changes, and occasionally mild Degree coagulation dysfunction. (2) Henoch-Schonlein purpura often develops due to increased permeability and fragility of the blood vessel wall, and changes in the vascular system, but the blood itself does not change. Therefore, the number of platelets tested, the clotting time, and the prothrombin time are all within the normal range. (3) Idiopathic thrombocytopenic purpura This disease, also known as hemorrhagic purpura, is of unknown cause. However, anti-platelet factors can be found in the blood of some patients. This factor can fight against platelets, causing platelet reduction and bleeding. According to the clinical manifestations, there are four main types: (1) Simple purpura generally has no systemic symptoms, and bright red petechiae scattered on the needle size can appear on both lower extremities, which does not fade. After seven days the color gradually faded and faded. But there are new petechiae. (2) Idiopathic thrombocytopenic purpura can be divided into two types, acute and chronic. Acute type is rare, can occur in children, and often has a history of infection before onset. The onset is characterized by a sudden onset, fever, widespread skin bleeding, large patches of ecchymosis, hematoma, and mucosal and urogenital system bleeding, and a significant reduction in platelets, which can be less than 5,000/mm3. Chronic type is more common, with more young people and slow onset. For persistent or recurrent bleeding. Not only occurs on the skin, but also on the mucous membranes or internal organs can also cause severe bleeding. (3) Rheumatoid purpura has slightly raised ecchymized rice grains on both lower extremities, and there may also be petechiae and wind spots
General term for purpura skin and mucous membrane color change after bleeding. The clinical manifestations are bleeding points, purpura, and ecchymosis. They generally do not rise above the skin surface. They can only bulge slightly in allergic purpura. They begin to be purplish red, and the color does not fade. Afterwards, they gradually become lighter and fade to yellow after about two weeks. . Treatment of allergic purpura: 1. Identify and remove the incentives to avoid suspicious related foods and drugs; remove the infected lesions, and apply antibiotics appropriately. 2. Rest in bed to facilitate the resolution of skin purpura and reduce its recurrence. 3. Those with simple skin type can be treated with antihistamines, butadiene, calcium gluconate, increased dose of vitamin C 3-5 grams, or glycyrrhizin. 4. For patients with allergic purpura or arthritis purpura with severe skin damage, moderate doses of corticosteroids or immunosuppressive agents may be given. Commonly used prednisone 0.5-1mg/kg/d, orally once a day, or an equivalent amount of dexamethasone or methylprednisolone intravenously drip daily, after the condition improves, change the prednisone orally, and gradually reduce the amount to stop medicine. The course of treatment is generally 1 to 2 weeks, kidney type can be extended as appropriate. Hormones are often ineffective for kidney type and cannot prevent relapse. Renal patients can be treated with immunosuppressive agents such as cyclophosphamide, azathioprine, and tripterygium wilfordii for a period of 2 to 3 months. Combination therapy with hormones and immunosuppressants can also be used. 5. For patients with purpuric nephritis, anticoagulant drugs such as dipyridamole (Pan Sheng Ding), heparin or low-molecular-weight heparin calcium can also be used, and Chinese medicine Zhikang capsules can also be used. 6, symptomatic treatment of joint swelling and pain can be taken orally aspirin (not for patients with intestinal bleeding); abdominal pain can be injected 654-2; gastrointestinal bleeding can be treated with omeprazole, cimetidine, etc. Limit diet when necessary; those with intussusception, intestinal obstruction, and hemorrhage should consider surgical treatment. 7. Treatment of traditional Chinese medicine The treatment plan of traditional Chinese medicine is aimed at the category of typhus. The wind and heat or damp heat attacks the blood and blood, causing heat to hurt the veins, making the blood not follow the meridian, overflowing outside the pulse, and staying in Caused by skin. Treatment should be based on the principles of wind-relief, heat-clearing, cooling blood and removing blood stasis.
Commonly used Western medicines for allergic purpura 1. Anti-allergic drugs: aspirin, chlorpheniramine, calcium gluconate. 2. Drugs to reduce vascular permeability: Anluoxue, Rutin, Vitamin C. 3. Platelet aggregation inhibitors: Pan Shengding 4. Adrenal corticosteroids: hydrocortisone, prednisone (prednisone), dexamethasone. 5. For those with poor treatment of kidney type or prednisone, immunosuppressive drugs (such as cyclophosphamide, azathioprine, etc.) are also used. Commonly used Chinese patent medicines for allergic purpura (1) Ning blood sugar syrup, use Yuqi does not take blood. (2) Tripterygium wilfordii polyglycoside tablets, used for allergic purpura with kidney damage. What medicines to take for allergic purpura are commonly used Chinese medicine prescription one: Rhizoma Dihuang soup flavored. Commonly used buffalo horn to clear the heart and cool blood; Shengliang Liangxue Yangyin; Paeonol, Chishao Huoxue Sanyu; Lithospermum, Scrophulariaceae cooling blood to stop bleeding; Scutellaria baicalensis, raw licorice clearing heat and detoxification. Those with tooth epistaxis, nose epistaxis plus fried gardenia, Baimao cold blood detoxification; urine blood Increase thistle and thistle cooling blood to stop bleeding; stool bleeding plus Burnet Charcoal, Sophora japonicum convergence to stop bleeding; pain in the abdomen reuse white peony root, licorice to relieve pain. If there is too much bleeding, suddenly pale, cold limbs, sweating In order to get rid of qi and yang, urgently use Dushen Decoction or Shenfu Decoction to return to yang solid prosthesis; if qi and yin have two failures, use Shengmai San to save yin and shengjin, and benefit Qi and replenish pulse. Addition and subtraction, commonly used rehmanniae, turtle version to nourish yin and yang to make false fire; yellow cedar, Apricot mother Qingxie fire; pig spinal cord, honey filled with moisturizing dryness. Cool blood to stop bleeding; those with low fever add Yinchaihu, Digupi, and Artemisia annua to clear away heat; night sweats add calcined oysters, calcined keel, and floating wheat to condense sweat and deodorant.
Allergic purpura, also known as Henoch-Schonlein purpura, is an allergic vasculitis that invades the small arteries and capillaries of the skin and other organs. It is often accompanied by abdominal pain, arthralgia, and kidney damage, but the platelet does not decrease. Some people think that allergic purpura and allergic skin vasculitis belong to the same lineage disease. etiology may be related to streptococcal infections, viral infections, drugs, food, insect bites, etc. The mechanism of occurrence is due to immune complex deposition or IgE-mediated vascular injury. There have also been reports of increased IgA in the serum of patients, and IgA deposition in the skin small blood vessel walls and glomerular tissues in skin lesions and non-skin lesions. Clinical manifestations are more common in children and adolescents, and may begin with fever, headache, joint pain, and general malaise. The lesions are characterized by petechiae, petechiae, or urticaria-like rash from the needle to the size of soybeans. In severe cases, blisters, blood blisters, and even ulcers may occur. Occurs in the extended sides of the limbs, especially the lower limbs and buttocks. The lesions are symmetrically distributed, appearing in batches and prone to relapse. Only those with skin damage are called pure purpura, and those with abdominal pain, diarrhea, blood in the stool, and even gastrointestinal bleeding are called gastrointestinal purpura; those with joint swelling, pain, and even joint effusion are called joint purpura; Hematuria, proteinuria, and renal damage are called renal purpura. Diagnosis Limb purpura with abdominal pain, arthralgia or kidney damage is not difficult to diagnose. However, when systemic symptoms appear before skin purpura, it is easy to be misdiagnosed as rheumatoid arthritis or acute abdomen. Clinically, these diseases and other types of purpura and vasculitis need to be identified. Treatment 1. Cause Treatment Actively seek out and treat possible causes. 2. Drug treatment (1) Antibiotic & nbsp. Those with infectious factors can choose appropriate antibiotics. (2) Antihistamines & nbsp. Suitable for simple purpura, rutin, vitamin C, calcium, Anluoxue or hemostatic can be used at the same time. (3) dapsone & nbsp. Early selection is effective. (4) Glucocorticoids & nbsp. It is suitable for severe skin damage or purpura of joint type, abdominal type and renal type. (5) Immunosuppressant & stubborn chronic nephritis patients can choose cyclophosphamide or azathioprine. Can be used in combination with glucocorticoids. (6) Symptomatic treatment . Antipyretic and analgesic drugs such as indomethacin and fenbide can be used for those with fever and arthralgia; oral or intramuscular injection of anisodamine or atropine intramuscular injection for abdominal pain; (7) Other treatments  . It has been reported to cure allergic purpura with cimetidine, compound salvia miltiorrhiza injection, tripterygium wilfordii, dextran-40, dipyridamole, etc. 3. Plasma exchange This method can effectively remove immune complexes in the blood circulation, thereby preventing blood vessel blockage and infarction. It is suitable for abdominal and renal patients with a large number of immune complexes in plasma.
Allergic purpura nephritis refers to renal damage caused by systemic diseases with necrotizing small vessel inflammation as the main pathological change in allergic purpura. Allergic purpura nephritis clinical manifestations in addition to skin purpura, joint swelling and pain, abdominal pain, blood in the stool, kidney involvement mainly manifests as hematuria and proteinuria, and some severe patients can cause impaired renal function. Kidney involvement usually occurs within days to weeks after skin purpura. etiology The etiology can be allergies caused by infections such as bacteria, viruses and parasites, or allergies to certain drugs and foods, or caused by plant pollen and insect bites. 1. Infection Some cases have a history of upper respiratory tract infection before onset. (1) Virus & nbsp. Epstein-Barr virus, adenovirus, rubella virus, etc. (2) Bacteria & salmonella, hemolytic streptococci, etc. (3) Parasites . Amoeba, roundworm, etc. 2. Drugs antibiotics, sulfonamides, captopril, etc. 3. Food Sea foods such as shrimp and crab. 4. Other plant pollen, insect eggs, animal feathers, paint, etc. According to the clinical manifestations of allergic purpura nephritis, the two types and classifications can be divided into the following six types: (1) solitary hematuria or solitary proteinuria; (2) hematuria and proteinuria; (3) acute nephritis type; (4) Nephrotic syndrome type; (5) rapidly progressive nephritis type; (6) chronic nephritis type. 2. According to the pathological changes of allergic purpura nephritis, according to the standards of the International Society of Children’s Nephropathy, it can be divided into the following six grades: (1) grade Ⅰ . minor lesions; (2) grade Ⅱ . simple mesangial hyperplasia; (3) Grade Ⅲ . Mesangial hyperplasia with glomerular crescent formation and/or segmental damage below 50%; (4) Grade Ⅳ . Mesangial hyperplasia with 50%～75% glomerular crescent formation and (Or) segmental damage; (5) grade Ⅴ . mesangial hyperplasia with crescent formation above 75% glomerulus and/or segmental damage; (6) Ⅵ . “pseudo” membrane proliferative nephritis. 3 Clinical manifestations (1) Extra-renal symptoms 1. Rash is the first and main clinical manifestation of the disease. The rash occurs on the distal limbs, buttocks and lower abdomen, and is symmetrically distributed. It is slightly higher than the skin surface and may be itchy. The interval from purpura to kidney damage is usually within 2 weeks. 2. Joint pain Common symptoms, characterized by multiple, non-migratory, more common in the ankle. 3. Gastrointestinal symptoms are common, mainly manifested as abdominal pain and diarrhea. Common sites are the umbilicus and lower abdomen. Sometimes paroxysmal colic. May have nausea, vomiting, and bloody stools. 4. Other Occasionally, lymphadenopathy, hepatosplenomegaly, and nervous system involvement such as headache, convulsions, and abnormal behavior are seen. （二）Kidney performance Kidney involvement occurs more than a few days to several weeks after the appearance of systemic symptoms and signs. The main manifestations are microscopic hematuria and proteinuria. Nearly half of the patients showed nephrotic syndrome, and some patients had decreased renal function. The degree of kidney involvement is not related to the severity of skin, gastrointestinal tract, and joint involvement. 4 Diagnosis of allergic purpura nephritis must meet the following three conditions: 1. Extrarenal manifestations of skin purpura with allergic purpura; 2. Clinical manifestations of renal damage, such as hematuria, proteinuria, hypertension, renal insufficiency Etc.; 3. Pathological changes of renal biopsy showed the deposition of IgA and mesangial hyperplasia in the mesangial area. 5 Differential diagnosis 1. Systemic lupus erythematosus is an autoimmune disease that often occurs in women of childbearing age. It can often involve the kidneys. Non-invasive arthritis, glomerular immune complex deposition, serum ANA, anti-dsDNA It is characterized by positive anti-Sm antibody. 2. Systemic vasculitis is a multi-system, multi-organ involvement vascular inflammatory disease, its serum anti-neutrophil cytoplasmic antibody (ANCA) is often positive, clinical manifestations are often rapid nephritis, pathological manifestations are Ⅲ Type (oligoimmune complex) crescentic nephritis. 3. Primary IgA nephropathy Primary IgA nephropathy is generally free of skin, joint and gastrointestinal tract manifestations of allergic purpura kidney damage, which is the biggest difference between primary IgA nephropathy and allergic purpura kidney damage. 4. Idiopathic thrombocytopenic purpura is a type of acquired hemorrhagic of unknown cause
Henoch-Schonlein purpura kidney, also known as kidney-type Henoch-Schonlein purpura, is a syndrome characterized by systemic small blood vessel damage as the main pathological basis, clinically characterized by skin purpura, kidney damage, hemorrhagic gastroenteritis, arthritis and so on. In patients with allergic purpura, kidney damage can occur in more than 1/3, and its prognosis mainly depends on the severity of nephropathy, so the kidney damage caused by allergic purpura is called allergic purpuric nephritis. The cause of the disease This disease often occurs in children under 10 years of age, and is rare in adults (>. 20 years old). It happened in the cold season. About one-third of patients have a history of infections with pioneers such as bacteria and viruses, but failed to prove a positive relationship with streptococcal infections. About 1/4 of the patients are related to fish or shrimp allergies or preventive injections and medicines. Most patients have a benign, self-limiting process, and most patients recover within a few weeks after proper treatment. However, there are also recurrent episodes or delays for months and years, and about 50% of patients have recurrent episodes. The incidence of allergic purpura nephritis in allergic purpura has been reported differently. Professor Tongtong Sun from Nantong Medical College reported 2840 cases at home and abroad, and 37.6% had purpura nephritis. Allergic purpura nephritis is a secondary lesion of allergic purpura, and the cause of allergic purpura is not yet clear, and may be related to infection and allergy. Some cases have infections before onset, the most common is upper respiratory tract infections (non-specific or streptococcal infections), others such as chlamydia, chickenpox and parasites. Many cases are allergic to drugs (antibiotic, iodine, isoniazid, salicylate, barbiturate and iodide) or food (milk, fish, shrimp, crab and clam, etc.) before illness. Currently considered to be an immune complex disease. IgA plays an important role in the pathogenesis. The serum IgA in patients with acute phase is significantly increased, and the affinity between IgA can produce high molecular weight polymers. In more than 90% of cases, the glomerular and small blood vessel wall of the skin have positive IgA immunofluorescence. The patient’s acute phase Ⅲ factor Ⅲ activity is low and there is fibrin (progen) in the glomerulus, suggesting that the coagulation mechanism is involved in the pathogenesis of this disease. Other immune abnormalities include: increased B cells secreted by IgA and changes in T regulatory cells. As for the exact mechanism of IgA in the pathogenesis of this disease, some are considered to be antigens, some are antibodies, and some are non-specific antibodies, which are produced simultaneously when the corresponding antibodies are produced after a certain antigen stimulates the body. Due to the high fibrin degradation product (FDP) in patients’ urine, fibrinogen is often deposited in the glomeruli. Therefore, the intravascular coagulation mechanism may also be involved in the pathogenesis of this disease. In addition to the performance outside the kidney, the disease is similar to IgA nephropathy in its history, clinical manifestations, and especially immunopathological changes. Therefore, some scholars believe that the two have a common pathogenesis, which is different clinical manifestations of the same disease.  Clinical manifestations of purpura nephritis (1) The manifestations of extrarenal symptoms include: ① rash, hemorrhagic and symmetrical distribution. The rash appeared as a red spot at the beginning, and disappeared when pressed. Later, it gradually turned into a purplish red hemorrhagic rash with a slightly raised skin surface. The rash is usually distributed symmetrically on both lower extremities, more commonly around the ankle and knee joints, and can be seen on the buttocks and upper extremities. When the rash subsides, it can turn into yellow-brown. In most cases, the rash can be repeated 1 to 2 times or at most 3 times, and individual cases can occur continuously for several months or even years. ② Joint symptoms are mostly characterized by wandering multiple arthralgia. Commonly affected joints are knees, ankles and hands. Symptoms subside within a few days, leaving no joint deformation. ③ Gastrointestinal symptoms manifested as abdominal pain, most commonly around the navel and lower abdomen, paroxysmal colic. May be accompanied by nausea, vomiting and bloody stools, and occasionally vomiting blood. In children, intussusception, intestinal obstruction, and intestinal perforation can sometimes be complicated. ④ Other symptoms, such as swollen lymph nodes, enlarged liver and spleen, a small number of hemoptysis caused by pulmonary hemorrhage, convulsions, paralysis and coma caused by hypertensive encephalopathy caused by nephritis or purpuric lesions of the brain. (2) Symptoms of kidney: more common within 4 to 8 weeks after the rash, and a few months later. Individually seen before the rash or 2 years after the rash. The most common manifestation is solitary hematuria, and 1/4 to 1/2 of cases are reported as gross hematuria in China. Proteinuria is mostly mild, but it can also develop into a lot of proteinuria and manifest as nephrotic syndrome. A few cases may have acute renal function deterioration. Some patients may have hypertension and edema purpuric nephritis clinical diagnosis and classification allergic purpuric nephritis diagnosis is mainly based on hemorrhagic rash and renal damage. Typical rashes are
Shi Shurong Studio WeChat xyk261 Many patients with allergic purpura know that they have purpura, they only pay attention to the skin purpura, but they ignore the normal urine routine! Urine routine is one of the three major clinical tests in the clinic. As a fecal examination, urine reflects the body’s metabolic status and is an important indicator for the diagnosis of many diseases. Many kidney lesions can appear in proteinuria or urine sediment early Formed elements appear. Abnormal urine is often a sign of kidney or urinary tract disease. Urine routine examination content includes urine color, transparency, pH, red blood cells, white blood cells, epithelial cells, cast, protein, specific gravity and urine sugar. For patients with allergic purpura, the first symptom of all patients is skin purpura. Allergic purpura is considered to be a skin disease, and it is blind to other symptoms or considered to be other diseases. But otherwise, allergic purpura is also manifested in joints and abdominal pain, and the most serious is the kidney type. So always pay attention to your urine routine. 30%-60% of children have clinical manifestations of kidney disease, called purpuric nephritis. Mostly appear in the course of 1-8 weeks, and there are also urinary abnormalities before the rash, and very few appear in 3-5 months. Symptoms vary, most of the children present with simple hematuria, proteinuria, individual severely ill children with a lot of proteinuria, edema, azotemia, hypertension or hypertensive encephalopathy, very few died of uremia due to acute renal failure disease. The severity of kidney disease is closely related to the prognosis. About 6% of children progress to chronic nephritis after a few years, and a few die from chronic renal failure. Severe kidney damage generally can use immunosuppressive agents, such as cyclophosphamide, tripterygium glycosides. But taking it for a long time will be dependent on the drug, and the condition will not improve afterwards. In such a situation, you can use traditional Chinese medicine treatment, cure by disease, cure by person, dialectical treatment, in the auxiliary process of Western medicine, you can achieve the withdrawal process.
Allergic purpura of the joint type is a type of allergic purpura. The clinical characteristics are clinical manifestations of joint pain and swelling caused by joint involvement except for a certain degree of skin purpura. 1 Clinical features The clinical features are the swelling and pain of the knee, ankle, elbow, and wrist joints before and after the appearance of skin purpura. The pain and swelling of the knee joint are the most significant, which can be wandering and repeated attacks. The physical examination shows that the affected joints have obvious Redness, swelling, heat, pain and dysfunction, there is a small amount of fluid in the joint cavity. Careful inspection can also find that the limbs, especially the lower limbs and buttocks, have unequal skin pressure spots, erythema or net Measles-like changes. Laboratory tests suggest abnormal capillary fragility test, accelerated erythrocyte sedimentation rate and positive C-reactive protein and other abnormal changes of diagnostic significance. The above is the main basis for doctors to diagnose arthritis purpura. 2 The treatment method is due to the joint type Allergic purpura is relatively rare, especially when joint pain and swelling of some patients appear before skin purpura, they are easily misdiagnosed as rheumatoid arthritis or other joint diseases. Therefore, when children have joint swelling and pain after the cold is cured , Should consider rheumatoid arthritis, but also consider allergic purpura of the joint type, and conduct a comprehensive inspection in time. Especially pay attention to the presence of skin petechiae, erythema, and urticaria-like changes, and the results of capillary brittleness test. In order to confirm the diagnosis in time and treat it reasonably. Allergic purpura of the joint has a good prognosis. After effective treatment for about 3 to 5 days, the joint swelling and pain swelling can be resolved, and no sequelae will be left after the resolution. However, it is necessary to be alert to its tendency to relapse and strengthen prevention The main principle of prevention is to find possible allergens (such as upper respiratory tract infections, certain foods such as fish, shrimp, crabs, eggs, etc.), certain drugs such as penicillin, streptomycin, non-steroidal anti-inflammatory drugs and quinine Etc.) and avoid it in the future. Among them, upper respiratory tract infection is the most common cause of allergic purpura in children. Therefore, do a good job in keeping warm, avoiding cold and rain, preventing accumulation of food, increasing exercise, improving body resistance and immunity Waiting becomes the main preventive measure after the child is cured.