5 perseverances that will keep you from uremia for life

Is there any nephropathy that is destined to have uremia? &nbsp. The answer is: yes! In common chronic kidney disease, these two kinds of kidney diseases are destined to develop into uremia, that is, polycystic kidney disease and hereditary nephritis (male), but the time to progress to uremia is longer or shorter. The final outcome must be uremia. As for other kidney diseases, as long as our kidney disease friends do “never give up”, in the end, they can completely avoid uremia, which can also be said to be “destined”. Conversely, no matter what kind of kidney disease is likely to get uremia, that is, patients with kidney disease are not “doomed” not to be uremic, and only those patients with kidney disease who have “worked and persisted” may laugh to the end. The last winner. 1. “Regular medication” requires “effort and perseverance”&nbsp.&nbsp.&nbsp.Whether it is kidney disease without any symptoms and signs found through physical examination, or nephropathy found after edema or gross hematuria, you must go to the regular hospital for treatment Further examination to confirm the diagnosis and active treatment. You can’t just “work hard” at the beginning, and you should use the medicine regularly and on time. But after a long time, they cannot “persist”, or think that there is no need to “struggle and persist” anymore. Such patients with kidney disease are destined to easily get uremia. 2. “Periodic inspection” requires “effort and persistence”&nbsp.&nbsp.&nbsp. After regular medication treatment, patients with kidney disease who have recovered, relieved, improved or stable must continue to “effort and persistence”, regular inspection and on time Referral. You cannot go to the hospital for examination or see a doctor for various reasons or excuses. Kidney disease is different from other diseases. It cannot be expected to solve all problems in one hospitalization or two or three outpatient visits. Follow-up periodic inspections and follow-up visits are essential. Nephropathy patients who cannot do regular inspections are destined to get uremia easily. 3. “Diet management” requires “effort and perseverance”. If the patient finds that he has kidney disease at the age of 30 and wants to live to 85, then he will have to eat about 60,000 meals, that is (85-30 years old) ×365 days ×3 meals = 60225 times (ton). Perhaps the vast majority of kidney disease friends can achieve short-term diet management, such as low-salt, light and high-quality low-protein diets, etc., they can “work and persevere” for weeks, months or years, but always feel that there is no need for long-term ” “Efforts and persistence”, or not at all. in fact. More than 60,000 meals seem to be unable to work hard and persevere, but once used to it, it is not difficult. If you cannot achieve long-term and scientific diet management, you are destined to get uremia easily. 4. “Lifestyle” requires “effort and perseverance” A free lifestyle is a taboo for patients with kidney disease, and a healthy lifestyle is the key to avoiding aggravation and progression of kidney disease. Healthy lifestyles include regular work and rest schedules, moderate physical exercise, perseverance, staying up late, quitting smoking and alcohol, and restraining sex. These healthy lifestyles not only require our kidney friends to work hard, but also persevere for a long time. Those nephropathy patients who have long-term poor lifestyles are destined to easily get uremia. 5. “Keep mentality” requires “effort and perseverance”. Maintaining a good mentality is also what our kidney patients need to pay attention to. After having kidney disease, we cannot be blindly optimistic or overly pessimistic. We must maintain a normal state of mind. To outsiders, few people can see that you have kidney disease. In the same way, one cannot always regard oneself as a patient. Speaking of patients, more than half of the 7 billion people on our planet suffer from various diseases of different severity. The average life expectancy of our Chinese people is still not close to 80 years old. Therefore, our kidney disease friends need not be afraid of it while attaching importance to it. People with kidney disease who live in fear all day or don’t care at all are destined to get uremia easily. &nbsp.&nbsp.&nbsp. After all, nephropathy destined to be uremic will definitely exist, but not destined to not be uremic. If our kidney patients cannot “never give up”, how can any kidney disease be destined not to have uremia? It all depends on the “effort and persistence” of our kidney disease friends.

If these three points are not done well, kidney disease may recur

Kidney disease is an “old and stubborn” in the eyes of many people. Once it occurs, it seems to have to be with it for life, which makes kidney friends very worried. Why can some diseases recover after a period of treatment, and even the sequelae will not remain, but kidney disease is a “lifelong disease”? For most people, nephropathy is detected early enough, and standardized scientific treatment can preserve the remaining renal function, and the risk of uremia is very small. There are also a small number of patients whose final prognosis is worse, and kidney failure or even uremia cannot be ruled out. So why is it difficult to completely cure kidney disease? You must know these three points about kidney disease! 1. Don’t just think about simply reducing the indicators. Although there are some key indicators that have a greater impact on renal function at different stages of kidney disease, simply controlling these indicators cannot fundamentally solve the problem of worsening renal function. This must be understood. . For example, creatinine value is an indicator to measure kidney function and judge uremia. Many people feel that creatinine has dropped and the condition has stabilized and they will no longer be treated. It is true that the change of creatinine means the detoxification function of the kidney. But to maintain a stable condition and delay renal failure, it is certainly not enough to control creatinine. It can’t be lowered just to lower the index. This is why some patients have creatinine that drops for a while and then rises again. 2. It is difficult to stabilize the disease by drugs alone. For the relief of some symptoms such as fatigue, nausea, edema, etc., and the reduction indicators including urinary protein, creatinine, uric acid, blood pressure, etc., targeted medication can quickly relieve symptoms and reduce indicators. But this is only temporary. To maintain stability for a long period of time, not only do you insist on medication, but also actively cooperate with daily care. Including the management of diet, changing the habits of kidney injury, and paying attention to the good habits of protecting the kidney. In the long run, kidney function can last and be stable. The causes of kidney disease are also related to some daily kidney injury habits such as long-term high-protein diet causing obesity, three highs, etc., as well as staying up late, smoking, not exercising, etc. will affect the body’s immunity, and then quietly damage the kidneys. 3. Chronic kidney disease re-examination every three months or half a year requires long-term monitoring, even if all indicators are improved. After fibrosis of kidney cells, some will be filtered by blood and metabolized with urine, but some damaged parts will form scars on the surface of the kidney, just like scars after scratching. These kidney scars are more sensitive. If infection or other disease factors occur, they may cause relapse. Therefore, regular reexamination is an important “weapon” to avoid repeated illnesses, and kidney friends should not lose it. Therefore, the “stubborn” kidney disease is not terrible. What is terrible is that after a long time of treatment, it is in vain. Kidney friends should learn to treat the condition from shallow to deep. Don’t just look at the surface, it is not difficult to get better control of your condition.

Regarding IgA nephropathy, kidney friends must also clarify these 10 common senses!

IgA nephropathy is the name of a pathological diagnosis, that is, a diagnosis made by renal puncture. It is a very common chronic kidney disease. In our patients with kidney disease, we often find that family members have IgA nephropathy at the same time, some parents (or mothers) and children (or daughters) have IgA nephropathy at the same time, and some of the brothers and sisters have IgA at the same time. Kidney disease. If the patient asks the doctor, the doctor generally does not say “IgA nephropathy is a genetic disease”. But the facts don’t seem to be like that, what the hell is going on? &nbsp.Family focusing tendency of patients with IgA nephropathy&nbsp. Maybe friends will have questions about what does “family focusing tendency” mean? Let me explain first, that is, some common characteristics presented by a family (usually referred to as first-degree relatives) are called family aggregation. A disease has “family focus” and may not necessarily be genetically related. For example, familial clustered hepatitis B is a disease related to infection; for another example, familial clustered esophageal cancer is related to the common eating habits or water quality of family members. Familial focus tendencies have very similar characteristics to familial focus, and familial focus tends to have a lower incidence of disease than familial focus. &nbsp.&nbsp.&nbsp. Returning to the problem that IgA nephropathy patients have a family-focused tendency. Obviously, IgA nephropathy has a family-focused tendency, which is neither related to infection nor eating habits. Studies have shown that IgA nephropathy has a strong genetic factor in the pathogenesis. At present, the genome-wide association study (GWAS) has identified 15 loci that are strongly associated with IgA nephropathy. Among these genes, 9 are related to the pathogenesis of IgA nephropathy, and 6 are related to the progression of IgA nephropathy. That is, different genes are involved in the entire process of IgA nephropathy. Of course, these 15 genes cannot explain all the known susceptibility sites, but only about 6-8% of the genetic heredity of IgA nephropathy, and more research is needed. &nbsp.&nbsp.&nbsp. Given that IgA nephropathy has a family-focused tendency, if one of the family members suffers from IgA nephropathy, it is recommended that first-degree relatives be examined for nephropathy to rule out the possibility of other family members suffering from the disease. &nbsp.&nbsp.&nbsp. In addition to being related to genetic factors, IgA nephropathy patients must also understand the following 10 useful kidney disease common sense. &nbsp.&nbsp.&nbsp.1. IgA nephropathy is the most common primary glomerular disease in the world (no one). &nbsp.&nbsp.&nbsp.2. The manifestations of IgA nephropathy are diverse, and the condition can be very mild or severe, and the treatments are also very different. &nbsp.&nbsp.&nbsp.3. The clinical course of the vast majority of IgA nephropathy is a benign process and should not be overtreated. &nbsp.&nbsp.&nbsp.4. Some patients with IgA nephropathy will eventually lead to end-stage renal disease: about 15-20% of patients progress from end-stage renal disease within 10 years after the first clinical manifestation; another 30-40% of patients End-stage renal disease occurs within 20-30 years. &nbsp.&nbsp.&nbsp.5. Renal biopsy pathology is still the gold standard for the diagnosis of IgA nephropathy. &nbsp.&nbsp.&nbsp.6. Including abnormal glycosylation of serum and urine IgA1 (Gd-IgA1), neutrophil gelatinase-associated apolipoprotein (NGAL), urine podocytes and related proteins, and angiostatin Markers including etc. can help patients with IgA nephropathy to identify or judge the progress and prognosis of the disease. &nbsp.&nbsp.&nbsp.7. As a basic treatment drug, the use of sartans or puli class drugs can significantly improve the prognosis of patients with IgA nephropathy. &nbsp.&nbsp.&nbsp.8. Usually IgA nephropathy may be induced within 72 hours of infection, so actively preventing and controlling infection is one of the important aspects of treatment in peacetime, and should defend the first line of defense for patients with IgA nephropathy. &nbsp.&nbsp.&nbsp.9. For patients with progressive IgA nephropathy who have a 24-hour urine protein quantification exceeding 1.0 g or a decline in renal function

Kidney function is not good, there are three items that must be checked!

Whether it is a daily physical examination or a routine examination for nephropathy treatment, to determine whether the kidney function is good or bad, you need to do some kidney-related examinations. Through the examination results, you can more accurately understand the condition of the kidney and the changes in the condition. Accurate examination results are the basis of treatment. There are many nephropathy examination items. Some patients have symptoms of discomfort for the first time, but the examination is not comprehensive, and the disease is not found in time, or the treatment is not timely, resulting in more and more serious illness and missed the best treatment. Time makes it difficult to reverse the condition. Nephropathy examination mainly includes two aspects: one to check blood and two to check urine, and different indicators reflect different kidney functions. Some inspections need to be reviewed multiple times, and some indicators can judge the results only once. Kidney function is not good, these three tests must be checked, no need to struggle! The three major examination items of urine examination are the routine urine examination. The indicators in the routine urine examination mainly reflect two aspects, inflammation and kidney problems. Nephropathy treatment-related indicators mainly include urinary red blood cells, white blood cells, urine protein, and urine specific gravity. High red blood cells and white blood cells indicate inflammation, specifically kidney inflammation or urinary tract inflammation, which needs further examination. The changes in urine protein and urine specific gravity can directly reflect the condition of the kidney. The presence of urine protein + is positive, and the increase in urine specific gravity indicates a problem with the kidney. Of course, the problem of transient urine protein should also be ruled out, that is, physiological factors such as eating too many high-protein foods, vigorous exercise before examination, etc. cause abnormal urine tests. Some patients in the early stage of kidney disease have no obvious symptoms, and there are often obvious abnormalities in the examination indicators, which are of great significance for the early treatment of kidney disease. Compare and see what happens to your test order? Urine morphological analysis sounds very high, what tests are they? Many kidney friends look at the test sheet and may have seen these indicators: tube type, crystal, bacteria, epithelial cells, etc. These tests have an important role in further determining the condition of kidney damage, such as a high rate of urine red blood cell deformation, mostly kidney The damaged glomerulus indicates glomerulonephritis. Urine protein in-depth inspection routine examination can find the presence of urine protein + sign, to clarify the situation of protein leakage, the degree of glomerular damage, the degree of impaired renal function, further urine related examinations are needed. Mainly include: 24-hour urine protein quantification, urine total protein creatinine ratio, urine albumin creatinine ratio and so on. The first two indicators have similar functions and can be replaced with each other, just check some of them. A large amount of protein leakage mainly reflects the impaired glomerular filtration function and the degree of glomerular lesions. In general, the more proteinuria, the more severe the damage to kidney function. The urine albumin creatinine ratio test is more accurate than the previous two tests. It can detect patients with kidney damage, but only mild proteinuria symptoms, such as diabetic nephropathy and hypertensive nephropathy. If you have a long history of sugar friends and high blood pressure patients, you will find that there is foam in your urine and no symptoms, but you can’t find any problems in urine routine. Remember to check this indicator. Two routine blood tests include blood creatinine, uric acid, and urea nitrogen. The kidneys are detoxifying organs. The increase in these indicators is a manifestation of increased levels of toxins in the body. It also indicates that the kidneys’ detoxification function is reduced. It’s half over. Hemoglobin Hemoglobin mainly plays the role of loosening blood oxygen to ensure normal blood flow rate. If abnormality occurs, most of them indicate anemia. In the middle and late stages of kidney disease, erythropoietin production decreases and spinal cord hematopoiesis decreases, and renal anemia occurs. A small number of patients often detect anemia first, and eventually diagnose kidney disease. Anemia will cause the degeneration of various functions of the body, in particular, it will cause a decline in immunity, which is not conducive to the stability and treatment of the disease. Renal function test In addition to the above tests, to further understand the examination of renal function, there are glomerular filtration rate, memory creatinine clearance rate, renal B ultrasound, electrolyte-related tests, etc. The abnormality of these indicators further indicates changes in renal function, and is particularly critical for the prevention of renal failure. More attention should be paid to the treatment.

What are the tests for poor kidney function? These three items must be checked, no need to struggle

Whether it is a daily physical examination or a routine examination for nephropathy treatment, to determine whether the kidney function is good or bad, you need to do some kidney-related examinations. Through the examination results, you can more accurately understand the condition of the kidney and the changes in the condition. Accurate examination results are the basis of treatment. There are many nephropathy examination items. Some patients have symptoms of discomfort for the first time, but the examination is not comprehensive, and the disease is not found in time, or the treatment is not timely, resulting in more and more serious illness and missed the best treatment. Time makes it difficult to reverse the condition. Nephropathy examination mainly includes two aspects: one to check blood and two to check urine, and different indicators reflect different kidney functions. Some inspections need to be reviewed multiple times, and some indicators can judge the results only once. Kidney function is not good, these three tests must be checked, no need to struggle! The three major examination items of urine examination are the routine urine examination. The indicators in the routine urine examination mainly reflect two aspects, inflammation and kidney problems. Nephropathy treatment-related indicators mainly include urinary red blood cells, white blood cells, urine protein, and urine specific gravity. High red blood cells and white blood cells indicate inflammation, specifically kidney inflammation or urinary tract inflammation, which needs further examination. The changes in urine protein and urine specific gravity can directly reflect the condition of the kidney. The presence of urine protein + is positive, and the increase in urine specific gravity indicates a problem with the kidney. Of course, the problem of transient urine protein should also be ruled out, that is, physiological factors such as eating too many high-protein foods, vigorous exercise before examination, etc. cause abnormal urine tests. Some patients in the early stage of kidney disease have no obvious symptoms, and there are often obvious abnormalities in the examination indicators, which are of great significance for the early treatment of kidney disease. Compare and see what happens to your test order? Urine morphological analysis sounds very high, what tests are they? Many kidney friends look at the test sheet and may have seen these indicators: tube type, crystal, bacteria, epithelial cells, etc. These tests have an important role in further determining the condition of kidney damage, such as a high rate of urine red blood cell deformation, mostly kidney The damaged glomerulus indicates glomerulonephritis. Urine protein in-depth inspection routine examination can find the presence of urine protein + sign, to clarify the situation of protein leakage, the degree of glomerular damage, the degree of impaired renal function, further urine related examinations are needed. Mainly include: 24-hour urine protein quantification, urine total protein creatinine ratio, urine albumin creatinine ratio and so on. The first two indicators have similar functions and can be replaced with each other, just check some of them. A large amount of protein leakage mainly reflects the impaired glomerular filtration function and the degree of glomerular lesions. In general, the more proteinuria, the more severe the damage to kidney function. The urine albumin creatinine ratio test is more accurate than the previous two tests. It can detect patients with kidney damage, but only mild proteinuria symptoms, such as diabetic nephropathy and hypertensive nephropathy. If you have a long history of sugar friends and high blood pressure patients, you will find that there is foam in your urine and no symptoms, but you can’t find any problems in urine routine. Remember to check this indicator. Two routine blood tests include blood creatinine, uric acid, and urea nitrogen. The kidneys are detoxifying organs. The increase in these indicators is a manifestation of increased levels of toxins in the body. It also indicates that the kidneys’ detoxification function is reduced. It’s half over. Hemoglobin Hemoglobin mainly plays the role of loosening blood oxygen to ensure normal blood flow rate. If abnormality occurs, most of them indicate anemia. In the middle and late stages of kidney disease, erythropoietin production decreases and spinal cord hematopoiesis decreases, and renal anemia occurs. A small number of patients often detect anemia first, and eventually diagnose kidney disease. Anemia will cause the degeneration of various functions of the body, in particular, it will cause a decline in immunity, which is not conducive to the stability and treatment of the disease. Renal function test In addition to the above tests, to further understand the examination of renal function, there are glomerular filtration rate, memory creatinine clearance rate, renal B ultrasound, electrolyte-related tests, etc. The abnormality of these indicators further indicates changes in renal function, and is particularly critical for the prevention of renal failure. More attention should be paid to the treatment. My name is Yang Yanfang. I am good at various glomerular diseases, such as IgA nephropathy, membranous nephropathy, hematuria, proteinuria, lupus nephritis, and treatment of chronic renal insufficiency. I have more than 40 years of clinical experience. Welcome to pay attention to this account. For related questions, you can leave a message or private message. After reading it, I will answer your confusion in detail.

It’s easy to destroy a kidney! 6 acts of death, some people do it every day

The human body has 2 kidneys, each kidney has 1 million nephrons, a total of about 2 million. When they are destroyed, the kidneys are destroyed. What is a nephron? A glomerulus filters the blood into raw urine, and a renal tubule filters the raw urine into final urine. As shown in the figure: a glomerulus + a renal tubule, connected together, is a renal unit with renal function. 2 million, sounds like a lot? But be aware that destroying them is actually very simple. These 2 million nephrons are non-renewable. The five intrinsic cells of the kidney have been highly differentiated and are destined to be non-renewable cells. Unlike the liver cells next door, they can also be regenerated. 2 million nephrons, only one-third of the nephrons are needed for daily work. Does it look good? In fact, the kidney is nothing more than to cover up its non-renewable vulnerability. How to kill nephron? 1. Eating outside, the daily intake of sodium for people with exhausted nephrons should not exceed 1500mg, otherwise it will significantly increase blood pressure and urine protein. However, according to the monitoring of nutrition and health status of Chinese residents in 2012, we found that our daily sodium intake was as high as 5706.7 mg, which is 3.8 times the appropriate intake, mainly because of eating too much salt (table salt is sodium chloride). In order to grasp the stomach of diners, restaurants usually put a lot of salt and oil in food and takeout. Some people like to order a lot of meat to eat, and they will unknowingly exceed the protein intake. Excessive salt, oil and protein will increase the burden on the kidneys. Some nephrons are overwhelmed and will be exhausted. Kidneys like you to go home to eat and make healthy meals yourself. 2. Stay up all night, the lack of sleep of the necrosis unit, the body will be in a state of tension for a long time, causing abnormal vasoconstriction, easy to induce continuous increase in systemic blood pressure and intrarenal pressure, and induce and aggravate kidney disease. Compared with people who sleep 7 hours a night, people who sleep less than 6 hours have a 70% increased risk of proteinuria. Proteinuria can cause nephron sclerosis, fibrosis and die completely. Smashed by a mobile phone or tablet in the middle of the night? It hit not only your face, but also your kidney. 3. Snacks, eat pickle of dead kidney unit, do you have much sodium? More, you can taste it with a lot of salt, very salty. Snacks, do they contain more sodium? Most people don’t know. Let’s take a look at the leader of sodium in snacks: the sodium content of plum. 100 grams of plum, containing 7660mg of sodium (remember the daily limit is 1500mg?), the total salt is 19.15g, “a bag of plum 1/5 is salt” is well-deserved. In addition, snacks such as spicy strips, dried beef, shredded squid, seaweed, ham sausage, potato chips, soda crackers, and melon seeds and peanuts are killers of large sodium-containing households and kidney units. 4. Sedentary, feeding the kidney unit thanks to the productivity development brought about by technology, modern people can eat and drink without much physical labor, and at the same time brings a drawback: sedentary. There are more and more patients with diabetes and hypertension in my country, and sedentary, lack of exercise, and obesity are important causes. In today’s nephrology wards, the most common type of kidney disease is diabetic nephropathy, and the number of patients with hypertensive nephropathy is also increasing year by year. Hyperglycemia and high blood pressure can hit the glomeruli and tubules at the same time, eventually causing irreversible necrosis of the nephron. 5. To hold urine, hold the bacteria in the urinary tract of the dead kidney unit to multiply one generation every 20 minutes, and to multiply nine generations in 3 hours, one bacteria can become 512 bacteria. There are 20 bacteria in 1ml of urine, which will reach more than 100,000/ml after 3 hours of reproduction, which may cause urinary tract infections such as “acute urethritis” and “acute cystitis”. Especially for women, due to physiological structure, urinary tract infections are very common, often from acute urinary tract inflammation to chronic nephritis, and then nephrons are killed one by one. 6. Tonic kidney, kidney kidney unit waist, sheep whip, collagen, soup, irregular medicinal diet, etc. People think that “big food” actually contains too much cholesterol, inferior protein, phosphorus, potassium, purine, As well as nephrotoxic substances, harm the nephrons. These so-called supplements not only do not supplement the kidney, but also damage the kidney. Both patients with kidney disease and healthy people must stay away. In our daily life, there are too many kidney-damaging behaviors, which are not listed one by one. Staying up all night and losing dozens of nephrons; eating a meal and drinking, and losing dozens of nephrons; coupled with sedentary, smoking, drinking, snacking, and wrongly nourishing the kidney, so much damage to the kidney Behavior, day after day, year after year,

Nephropathy urine loss must be renal failure? Don’t worry, there are chances to save if you do 2 points

Whether it is a daily physical examination or a routine examination for nephropathy treatment, to determine whether the kidney function is good or bad, you need to do some kidney-related examinations. Through the examination results, you can more accurately understand the condition of the kidney and the changes in the condition. Accurate examination results are the basis of treatment. There are many nephropathy examination items. Some patients have symptoms of discomfort for the first time, but the examination is not comprehensive, and the disease is not found in time, or the treatment is not timely, resulting in more and more serious illness and missed the best treatment. Time makes it difficult to reverse the condition. Nephropathy examination mainly includes two aspects: one to check blood and two to check urine, and different indicators reflect different kidney functions. Some inspections need to be reviewed multiple times, and some indicators can judge the results only once. Kidney function is not good, these three tests must be checked, no need to struggle! The three major examination items of urine examination are the routine urine examination. The indicators in the routine urine examination mainly reflect two aspects, inflammation and kidney problems. Nephropathy treatment-related indicators mainly include urinary red blood cells, white blood cells, urine protein, and urine specific gravity. High red blood cells and white blood cells indicate inflammation, specifically kidney inflammation or urinary tract inflammation, which needs further examination. The changes in urine protein and urine specific gravity can directly reflect the condition of the kidney. The presence of urine protein + is positive, and the increase in urine specific gravity indicates a problem with the kidney. Of course, the problem of transient urine protein should also be ruled out, that is, physiological factors such as eating too many high-protein foods, vigorous exercise before examination, etc. cause abnormal urine tests. Some patients in the early stage of kidney disease have no obvious symptoms, and there are often obvious abnormalities in the examination indicators, which are of great significance for the early treatment of kidney disease. Compare and see what happens to your test order? Urine morphological analysis sounds very high, what tests are they? Many kidney friends look at the test sheet and may have seen these indicators: tube type, crystal, bacteria, epithelial cells, etc. These tests have an important role in further determining the condition of kidney damage, such as a high rate of urine red blood cell deformation, mostly kidney The damaged glomerulus indicates glomerulonephritis. Urine protein in-depth inspection routine examination can find the presence of urine protein + sign, to clarify the situation of protein leakage, the degree of glomerular damage, the degree of impaired renal function, further urine related examinations are needed. Mainly include: 24-hour urine protein quantification, urine total protein creatinine ratio, urine albumin creatinine ratio and so on. The first two indicators have similar functions and can be replaced with each other, just check some of them. A large amount of protein leakage mainly reflects the impaired glomerular filtration function and the degree of glomerular lesions. In general, the more proteinuria, the more severe the damage to kidney function. The urine albumin creatinine ratio test is more accurate than the previous two tests. It can detect patients with kidney damage, but only mild proteinuria symptoms, such as diabetic nephropathy and hypertensive nephropathy. If you have a long history of sugar friends and high blood pressure patients, you will find that there is foam in your urine and no symptoms, but you can’t find any problems in urine routine. Remember to check this indicator. Two routine blood tests include blood creatinine, uric acid, and urea nitrogen. The kidneys are detoxifying organs. The increase in these indicators is a manifestation of increased levels of toxins in the body. It also indicates that the kidneys’ detoxification function is reduced. It’s half over. Hemoglobin Hemoglobin mainly plays the role of loosening blood oxygen to ensure normal blood flow rate. If abnormality occurs, most of them indicate anemia. In the middle and late stages of kidney disease, erythropoietin production decreases and spinal cord hematopoiesis decreases, and renal anemia occurs. A small number of patients often detect anemia first, and eventually diagnose kidney disease. Anemia will cause the degeneration of various functions of the body, in particular, it will cause a decline in immunity, which is not conducive to the stability and treatment of the disease. Renal function test In addition to the above tests, to further understand the examination of renal function, there are glomerular filtration rate, memory creatinine clearance rate, renal B ultrasound, electrolyte-related tests, etc. The abnormality of these indicators further indicates changes in renal function, and is particularly critical for the prevention of renal failure. More attention should be paid to the treatment.

5 kinds of kidney disease can not be eradicated

Recently, several kidney friends with diabetes and hypertension consulted, asking when can the medicine be stopped? In fact, diabetes and hypertension are incurable diseases, and the chronic renal failure caused by them is also incurable, requiring lifelong treatment. The following types of kidney disease cannot be eradicated: 1. Diabetic nephropathy Diabetes cannot be cured, and kidney disease caused by diabetes cannot be eradicated. 2. Hypertensive nephropathy Essential hypertension requires taking antihypertensive drugs for life, so hypertensive kidney damage cannot be completely cured. 3. Lupus nephropathy treatment of lupus nephritis is very long, most patients need to take small doses of glucocorticoid maintenance treatment for life to avoid recurrence. 4. In the literature statistics of hepatitis B related nephropathy, there are very few hepatitis B related nephropathy. However, this is just because patients with hepatitis B and kidneys rarely perform renal puncture. 5. Chronic renal failure includes the stage in which various kidney diseases develop into chronically impaired renal function. Because the kidneys have already hardened and necrotic cells cannot be regenerated, chronic kidney failure cannot be cured. There is no cure, is it worthless? No, incurable ≠ the end point is uremia. In fact, after middle age, anyone’s kidney function will gradually decline, but the kidney function of patients with kidney disease will decline faster. Even for incurable kidney disease, treatment can be used to delay the decline of kidney function and make it as close as possible to the decline of kidney function in normal people. Although the above nephropathy is incurable, it does not mean that the treatment has failed. When the patient is old, and near the end of life, renal function is still sufficient, is it not a success? My name is Bai Zhicheng. I am good at various glomerular diseases, such as IgA nephropathy, membranous nephropathy, hematuria, proteinuria, lupus nephritis, and treatment of chronic renal insufficiency. I have more than 40 years of clinical experience. You are welcome to pay attention to this account. For related questions, you can leave a message or private message. After seeing it, I will answer your confusion in detail.

Membranous nephropathy, 3 ways can be treated

According to past kidney biopsy statistics, membranous nephropathy accounts for about 15% of chronic kidney disease in my country. However, with the improvement of people’s living standards, overnutrition is becoming more and more common; coupled with the promotion of PM2.5 and other pollutants, the incidence of membranous nephropathy is rising. According to the pathological statistics of the Second Affiliated Hospital of Hebei Medical University, the incidence rate has reached 30% in the central and southern Hebei Province, and the proportion of new-onset membranous nephropathy has exceeded 50%. Today, it has become a dark horse and should not be underestimated. A dark horse in the family of nephropathy: membranous nephropathy, three methods can be treated. The disease originates from a layer of membrane. The main function of the kidney is to turn blood into urine, how to do it? Let the blood pass through its capillary wall, filter it, and the blood becomes the original urine. This blood vessel wall is like a sieve, with 3 layers, including 2 layers of “fences”, and a membrane between the two fences. This membrane is called the basement membrane, and it is an important layer that can filter out the waste in the blood. If the basement membrane changes (immune complex deposition, spike formation, etc.), it is called membranous nephropathy. At this time, the fence was broken, and the protein that normally couldn’t see through this membrane leaked out of the fence, and it was eliminated together with urine, and urine protein increased. When urinary protein passes through the kidney, it will cause fibrosis, sclerosis, and atrophy of the kidney. If it continues for a long time, it will gradually progress to uremia. Membranous nephropathy is a pathological name that provides guidance for the treatment plan and does not have much effect on the severity. There are stages of membranous nephropathy: stages 1-4. The later the stage, the greater the possibility of serious, but it is not strictly corresponding, and there are too many exceptions. Whether the condition of membranous nephropathy is serious depends on whether the urinary protein has been relieved after medication. The prognosis varies greatly. About one-third of the patients can relieve themselves, and about one-third of the patients are ineffective in treatment. 1. Conventional treatment If the 24-hour urine protein of membranous nephropathy is below 3.5g; or between 3.5g-8g, and the renal function is normal and there is no high-risk phenomenon, usually immunotherapy is not used, but Chinese medicine, Puly drugs and satanic drugs reduce urine protein, and give diuretic, antihypertensive, anticoagulant and other supportive treatment. 2. Hormone combined immunosuppressive agents If the 24-hour urine protein of membranous nephropathy exceeds 3.5g and is accompanied by decreased renal function, or urine protein exceeds 8g, immunotherapy should be applied. Hormone alone is not effective for membranous nephropathy, and it needs to be combined with hormone + immunosuppressive agent. It is recommended to combine Chinese medicine treatment to achieve better results. 3. Monoclonal drugs If the hormones and immunosuppressive drugs are not effective, monoclonal antibodies can be used, such as rituximab and belidomumab, which can often achieve better therapeutic effects.

How is uremia formed?

After many people have kidney disease, they become uremia indistinctly. It is even unclear when the kidney started to be “injured”. Uremia is not a single-onset disease, it is the end stage of the development of chronic kidney disease, that is, the state of kidney failure. So where does chronic kidney disease come from? Chronic kidney disease is mainly divided into two categories, one is primary kidney disease, and the other is secondary kidney disease. 1. Primary nephropathy Primary nephropathy refers to a disease that originates inside the kidney, such as glomerulitis, pyelonephritis, occult nephritis, and kidney stones. If it does not recover after more than 3 months, and the relevant examination indicators are always abnormal, or the effective glomerular filtration rate is less than 60%, it can be regarded as “chronic kidney disease”. 2. Secondary kidney disease is caused by other diseases. The secondary kidney disease, such as high blood pressure, is like pressing a mountain on the kidney. It is likely to cause excessive blood vessel pressure, protein leakage, and structural effects on the filter. The destruction eventually leads to hardening of the kidneys. Another example is diabetic nephropathy, which has become the second leading cause of uremia. Excess blood sugar will produce a large amount of glycosylation end products, which are deposited in the kidneys, block the renal tubules and blood vessels, cause various inflammatory reactions or microvascular lesions, and eventually “stretch” the glomeruli. In addition, gout, lupus erythematosus, and hyperlipidemia are all high-risk factors. If it cannot be cured or contained effectively, it can easily develop into uremia.

Many kidney diseases require long-term use of hormones. How does it treat kidney disease? In-depth interpretation

Hello everyone, I am a nephrologist. When it comes to hormones, nephrologists probably have the right to speak, because many nephropathy patients are hormone users. For the special drug “hormone”, some say it is good, some say it is bad. Our sayings are good, we have real knowledge in practice, and the more we use and the more we see, the more experienced we are. As a nephrologist who has been dealing with hormones for a long time, today I will unveil the mysterious veil for everyone. What are hormones? ●Many rumors on the Internet say that hormones are life-threatening, @头条开谣, saying what will happen if you eat it. In fact, I might as well tell you that many of them don’t even know “what is a hormone”, just because there is a rhythm. If I think that “hormones” are just a class of drugs, I can only say that the understanding is too superficial. Hormones are actually secreted by our body all the time, like parathyroid hormone, growth hormone, glucagon, and cortisol are all “hormones” secreted by the body itself, it plays an important role in our life activities, and we also Use it. Due to the relatively large space, today I focus on explaining “glucocorticoid” and its application in kidney disease. ●The adrenal glands of our normal people (a small organ of the human body) can secrete about 10-20mg of cortisol (also known as glucocorticoid) every day. It has a characteristic of secretion, that is, it is released in a pulsating manner, with obvious day and night laws. It is the lowest during sleep at night. It begins to rise after 3-5 hours of falling asleep. It wakes up in the morning and reaches its peak, and then begins to decline again. It is such a cyclic process that its secretion is mainly affected by our high-level center (hypothalamus- Pituitary-adrenal) control. ●What are the types of glucocorticoid preparations of the drug? The classification of the drugs is mainly based on the half-life of the drug. According to its pharmacological characteristics, it can be divided into three types: short-acting, medium-acting and long-acting. Short-acting half-life is about 6-12 hours, more representative drugs such as cortisone, hydrocortisone; medium-acting half-life is about 12-30 hours, more representative drugs such as prednisone , Prednisolone, methylprednisolone, etc.; long-acting half-life is about 48-72 hours, more representative drugs such as dexamethasone, betamethasone, etc. How to use hormones in patients with kidney disease? ●According to the pathology of renal puncture, nephrotic syndrome can be divided into multiple types. Like effective pathological types of glucocorticoid alone: ​​minimally diseased nephropathy (more common in children), mesangial proliferative nephritis (more common in adolescents, including IgA nephropathy), focal segmental glomerulosclerosis FSGS (child More common in adolescents); the type of cytotoxic drugs that need to be combined (such as cyclophosphamide CTX): idiopathic membranous nephropathy & nbsp. (This is only a general division, and may be slightly different in clinical practice) ●However, hormone therapy is not Speaking of nephropathy, it is all right. According to the response after treatment, it can be roughly divided into three categories, that is, sensitive type: that is, clear pathology. After active and sufficient medication, the symptoms of nephrotic syndrome (edema, proteinuria, etc.) are quickly relieved; Dependence: that is, the effect is good during the treatment, and it begins to relapse after the reduction. (We talk about recurrences can be divided into 2 subcategories: infrequent recurrence: that is, once in the first 6 months and less than 3 times in 1 year. Frequent relapse: more than or equal to 2 times in 6 months and more than 3 times in 1 year) ● The last one is the hormone resistance type. Simply put, it is useless to use hormone therapy. Our evaluation standard is that the puncture is in accordance with a certain type of nephrotic syndrome, but you use it regularly and reach the treatment cycle of 8-12 weeks without remission. , Need to actively find the cause, such as whether it is complicated by infection, thrombosis, unspecified medication, gastrointestinal edema, etc. If there is no above-mentioned predisposing factors, consider adding immunosuppressive agents or other special treatment options. Personal experience of using hormones in patients with primary kidney disease ●For patients with kidney disease who need to use hormones, this medication principle must be followed. First, the starting amount should be sufficient. I take methylprednisolone as an example. The general therapeutic dose is 0.8-1.0mg. kg.d, roughly 40-60mg/day, mainly oral, and some slower reactions such as FSGS can reach 16-24 weeks (some people are afraid of side effects of hormones and reduce their doses by themselves. ) ● Second, reduce the drug slowly, that is to say, it will start to decrease every 2 weeks after reaching the time of full use

What factors can induce uremia?

Uremic disease (also known as end-stage renal disease) is a common outcome of chronic kidney disease, but not all chronic kidney disease develops into uremia. So, what factors can induce uremia? Five major factors that induce uremia: One is nephropathy. Nephropathy is the main cause of uremia. Early kidney disease often accelerates the development of the disease due to patients’ lack of attention to lifestyle habits, especially bad habits such as staying up late, working hard, and overeating. It is more likely to cause uremia. Factor 2: Hypertension Uremia is a common complication of hypertension. 50% of patients with hypertension may be converted to uremia. Hypertensive patients should actively cooperate with treatment to control blood pressure and improve their condition. Factor three: urinary infections Urinary infections have a certain relationship with uremia, whether men or women may induce uremia. In my country, chronic pyelonephritis is the second factor of uremia, accounting for 21.2%. Married women are more prone to urinary sensation, and the risk of uremia is greater. Factor 4: Diabetes Diabetic nephropathy is the most common complication of diabetes, and diabetic nephropathy patients have uremia, especially in patients with low glucose tolerance, and there is a high probability of inducing uremia. Factor 5: Toxic and side effects of drugs Related statistics show that nearly 30% of patients with kidney failure have toxic and side effects due to long-term use of analgesic cold medicines, resulting in problems with kidney function and finally causing uremia. Once uremia occurs, the “toxicity” is systemic. A complication of the skin during the uremic phase, hyperphosphatemia, means that the phosphorus content in the body exceeds the standard and cannot be excreted through urine. Some toxins want to be excreted through sweat. If there is too much phosphorus content, it will cause skin itching. The skin will also have other lesions in early summer, such as melanoma, plaques, and purulent infections. Three channels for the body to excrete toxins, urine, sweat, and feces. When the main passage of urine is blocked, sweat and feces will bear more responsibilities. With the extension of the course of the disease, the gastrointestinal reaction will become more and more obvious. The shortness of breath may just be loss of appetite, nausea, vomiting. The accumulation of sex toxins can gradually stimulate the gastrointestinal mucosa to cause cellulose inflammation, and it is also possible to form ulcers and bleeding. Patients in the uremia stage will have anemia symptoms more or less. At this time, uremic patients can only fight erythropoietin to help the body hematopoiesis. Nervous system damage usually manifests as early headache, fatigue, irritability, and severe insomnia. In the later stages, symptoms such as consciousness disturbance and coma will appear. In patients with nephropathy in the uremic stage, the cardiovascular system becomes extremely vulnerable and dangerous. The symptoms of the disease on this system are mainly heart failure and arrhythmia. Although this usually occurs in the middle and late stages, it will threaten the life safety of patients with kidney disease. Once detected, except for lifelong dialysis, there is only a kidney change. In fact, uremia has a precursor, which is the result of the combined effect of poor life and eating habits. Four kinds of foods are accelerators of “uremia”: the first kind: salty foods such as pickles, salt can be said to be an essential condiment in life, if the normal intake of salt is good for the body. However, people’s dietary tastes are generally high, resulting in salt far exceeding the normal daily recommended amount. This results in eating too salty, which increases the burden on the kidneys. In addition, excessive intake of sodium will cause the electrolyte imbalance in the body, and the body’s water is not easily discharged, further increasing the burden on the kidneys. The second type: foods with high phosphorus content. Phosphorus in the human body needs to be discharged through glomerular filtration. Long-term consumption of foods with high phosphorus content will inevitably increase the burden on the kidneys, reduce kidney filtration function, and damage the kidneys over time. Therefore, aquatic products, animal livers, egg yolks and dried fruits need to pay attention to control intake. The third type: carambola carambola has a neurotoxin, also called carambola toxin, which can cause damage to brain and kidney functions. For healthy people, eating carambola has no threat and can be excreted from the body smoothly. If you are a kidney patient or have a history of kidney disease, it is best not to eat carambola, in order to prevent aggravating kidney disease, or lead to kidney disease recurrence, poisoning and life-threatening. Fourth: Lamb Mutton is a high-purine food, which is likely to cause elevated uric acid levels. At the same time, lamb also contains a lot of animal fat, which is not easy to digest into the body and increase liver metabolism. At the same time, it will promote renal arteriosclerosis, atrophy and degeneration of the kidneys, and cause arteriosclerotic nephropathy.

Have kidney disease, the body has 5 precursors, early or may save your life

“Xiaojiu, can I “applause for love” if I have chronic kidney disease?” Recently, Xiao Zhang went to the hospital because of physical discomfort and was diagnosed with “chronic kidney disease”. When I heard that I had “kidney disease”, it scared Xiao Zhang enough. Since ancient times, people have linked “kidney” with “sex”. Rumor has it that kidney disease is a function that does not work in that aspect. I must say goodbye to sex life! Thinking of being an unmarried young guy, he could only be a pure-hearted “monk” from now on. Xiao Zhang couldn’t believe it. But when he asked the doctor in front of everyone, he was embarrassed, so he asked Xiao Jiu in a private letter. not true? Today, chronic kidney disease is already a common disease. According to statistics, the total prevalence of chronic kidney disease in China is 9.3%, that is, one in ten people has kidney disease. Once the kidney is damaged, as the condition gets worse, not only will the treatment become more difficult, but it will also affect the physical and mental health of the patient. In addition to worrying about the effectiveness of kidney disease treatment, they also worry about not having sex, after all, sex is often related to the relationship between couples. In fact, whether a person with chronic kidney disease can live in a “two-person world” depends on the severity of the condition and the individual’s physical condition. It is impossible to say that kidney disease can say goodbye to the same room, but it cannot be said that kidney disease has nothing to do with the same room. We all know that the same room is a vigorous systemic activity, which will be accompanied by accelerated blood circulation, high nerves, etc., and the workload of the kidneys will increase significantly than usual. Therefore, most normal people will be accompanied by different levels of fatigue after the end of the same room, but after a certain period of rest, they can completely return to normal. For patients with long or severe kidney disease, the fatigue time after the same room will be longer and the physical recovery will be slower. If the number is too many, it may lead to the recurrence and aggravation of kidney disease because the immune function of the body has not been fully restored. . Therefore, whether patients with kidney disease can be in the same room depends on the situation, and if appropriate, an appropriate amount should be taken care of to prevent injuries caused by too many times. It is generally recommended that patients with kidney disease can be in the same room as healthy people without severe renal impairment and obvious clinical symptoms. It is not appropriate to stay in the same room during acute nephritis, acute stage of chronic nephritis, or the condition is still unstable, so as not to aggravate the condition or not conducive to the rehabilitation of the disease. If the patient is in a stable state of chronic nephritis rehabilitation, he can be in the same room appropriately according to the condition, but avoid excessive, it is recommended to be carried out once every 2 to 3 weeks to nourish the kidney and facilitate the rehabilitation of kidney disease. If a patient with kidney disease is really not sure whether he can be in the same room or how many times it is appropriate, Xiao Jiu suggests, don’t be ashamed, and ask the doctor boldly. The doctor recommends the most reliable and the most important thing to protect your “kidney”. As we said before, chronic kidney disease can still lead a sex life when the condition is stable or not serious, which is very encouraging news for many patients. However, Xiao Jiu feels that once suffering from chronic kidney disease, it will have a great impact on our body and life, and even cause uremia and death. Therefore, for patients with chronic kidney disease, it is imperative to find out the cause of chronic kidney disease, prevent it as soon as possible, and stay away from the disease. First of all, the increase in chronic kidney disease is mainly due to the increasing incidence of common diseases that may cause kidney damage, such as diabetes, hypertension, hyperuricemia, and obesity. These diseases can cause kidney disease or uremia. However, the occurrence of these diseases is usually closely related to bad habits. Therefore, everyone should always maintain good living habits, pay attention to diet and nutrition, and not overeating. Appropriate exercise, physical fitness, quitting smoking and drinking, not staying up late, etc. are also very important. Secondly, blindly taking various Chinese and Western medicines results in a large amount of medicines accumulating in the kidneys, increasing the excretion burden of the kidneys, and also causing damage to the kidneys, resulting in kidney disease. Therefore, in the process of seeking medical treatment, in order to prevent the doctor from prescribing the medicine repeatedly, it is recommended that you tell the situation of the medicine you take in advance so that the doctor can accurately prescribe the medicine. Don’t believe in remedies and do not use drugs indiscriminately. Finally, the increasing number of patients with kidney disease is also closely related to my country’s current aging population. With increasing age, kidney function will decrease accordingly. Therefore, the elderly must pay more attention to the protection of the kidneys, pay attention to the lifestyle and safety of medication. Chronic kidney disease often has no obvious symptoms. In addition to strengthening the prevention of kidney disease in daily life, it should also go to the hospital for regular inspections so that it can be discovered and treated as soon as possible. Therefore, everyone usually

What is nephrotic syndrome? Can it be cured?

What is kidney disease? Renal syndrome actually refers to a group of clinical syndromes, mainly manifested as a large amount of proteinuria, urine protein greater than 3.5g/day, hypoalbuminemia (blood albumin &lt.30g/L), edema, hyperlipidemia Four aspects, including large amounts of proteinuria and hypoalbuminemia are necessary conditions. What is nephrotic syndrome? Can it be cured? How do you get kidney syndrome? Nephrotic syndrome is divided into primary, secondary and hereditary according to the etiology. Primary nephrotic syndrome refers to a kidney disease caused by problems in the kidney itself. Secondary kidney syndrome is a nephrotic syndrome caused by other diseases, such as diabetes, lupus erythematosus, and multiple myeloma. Hereditary kidney syndrome is associated with genetic disease. What is nephrotic syndrome? Can it be cured? Can nephrotic syndrome be cured? According to the etiology, pathological manifestations, drug response, compliance and other aspects of comprehensive consideration, the treatment effect of nephropathy in different situations is different, and some nephrotic syndrome can be cured. If it is a small lesion, most of it can be cured. If it is membranoproliferative glomerulonephritis, the treatment effect is very poor. Such as diabetic nephropathy, the symptoms of nephrotic syndrome have already appeared, the treatment effect is poor, and the chance of reversal is small; for lupus nephritis, the treatment effect depends on the specific pathological type. In short, everyone’s response to various drugs is different, and the effect of treatment is also different. The patient’s own problems with drug response, complications, and patient compliance issues all affect the therapeutic effect of nephrotic syndrome. Nephrotic syndrome does not take hormones for life, like most minor lesions, membranous nephropathy, etc. If the drug treatment is good, it can basically be discontinued. In some refractory nephrotic syndromes, the drug response is poor, and the time for taking the drug will be prolonged. The specific time for stopping the drug depends on the specific situation of the patient, but it is generally not necessary to take hormones for a lifetime. What is nephrotic syndrome? Can it be cured? How to keep kidney complex from recurring? After the kidney disease is improved or cured by treatment, to ensure that it does not recur, it is necessary to follow the doctor’s guidance and adjust the medicine. In terms of life, you should avoid infection, fatigue, and do not take medicine disorderly. Regularly go to the hospital for re-examination, and promptly treat any problems.

These 5 sudden symptoms all indicate that you have entered the stage of kidney failure

At the age of 30, Xiao Chen was engaged in the hairdressing industry. At the beginning of this year, he began to feel something was wrong. He woke up two or three times a night, and his urine was yellow and muddy, and there was a layer of foam. In addition, he often felt that his waist was weak. At first he thought he was tired from work. After taking a few days off at home, he felt that his symptoms did not improve. On the advice of his family, he went to the Nephrology Department of the hospital for treatment. As soon as the test result is out, Xiao Chen can be scared: blood creatinine has reached 640+, and he has suffered from chronic renal failure. Xiao Chen is unbelievable. Why did he suffer from kidney failure for a period of time? Regrettably: The five symptoms all indicate that you have entered the stage of renal failure and take you to understand renal failure. We know that renal failure is divided into acute and chronic. There are many causes of acute renal failure, usually due to drug abuse, sudden acute hemorrhage of the renal artery, etc., and the disease is obvious and the disease develops quickly, and the patient can basically detect it in time. Chronic renal failure is more common clinically, because some disease factors, such as kidney disease, are not found in time for treatment. Chronic failure of kidney function with the development of the disease in the long-term past is generally not obvious, so patients It is difficult to detect in time, but when the patient shows obvious discomfort, the kidney function is almost completely failed. Renal failure is not controlled, and the emergence of uremia quietly means that the emergence of uremia means that chronic renal failure has entered the advanced stage. At this time, the functions of kidney excretion, acid-base balance, water and ion balance have been almost completely lost. Therefore, uremic patients basically need dialysis treatment to replace kidney function. The whole process of dialysis treatment is very painful. It is necessary to first draw the blood in the body and then filter it by the machine to separate the various toxic components accumulated in the blood due to the damage of kidney function from the blood, and then retransmit the blood back to the patient. And this process needs to be performed 3 times a week, and the treatment cost is expensive. At the same time, patients with advanced renal failure may also face serious infection or failure of other multiple organs due to uremia and other reasons, and eventually lead to death. Therefore, if there is no timely detection and effective treatment in the early stage of renal failure, once the advanced stage is reached, both the body and the spirit will suffer unimaginably great pain. However, if you can notice some symptoms in the early stage of renal failure, the treatment and control of the disease will be simpler. These symptoms may occur in the early stage of renal failure: 1. Edema. The most common symptom of early renal failure is edema. Because abnormal kidney function will directly lead to abnormal metabolic system. When there is a problem with water metabolism, it can cause edema, which often occurs on the face, ankles, and eyelids. 2. Abnormal urine. Metabolic abnormalities due to renal failure, so patients with renal failure will have too much or too little urine, urine foam, abnormal urine color, hematuria, proteinuria and other symptoms. 3. Severe low back pain The kidney disease will cause other related nerves and organs to have problems in succession, and there are many lumbar nerves around the kidney. Therefore, when the kidney function is abnormal, it may press the lumbar nerves and feel severe low back pain. 4. Hypertensive renal failure leads to abnormal metabolic system, which makes the various ion components in the body unbalanced, which can easily lead to other serious complications such as hypertension. 5. Other physical discomforts Because of kidney function problems, various toxins accumulate in the body, which can also cause nausea, insomnia, anemia, lack of energy, skin diseases and other symptoms of physical discomfort. Abnormal renal function will certainly have a great impact on your health, but if you already have some kidney diseases, you don’t need to be too negative. There are many clinical patients with kidney disease who have not entered the late stage of renal failure for more than ten years or even decades. Because the kidney has a strong compensatory function, 50% of normal kidney function is enough to support the body’s needs, so it is not terrible to suffer from kidney disease. It is important to learn to control the disease from worsening and prevent kidney failure. To avoid kidney failure, patients with kidney disease need to do these points: · Control blood sugar and blood pressure If blood sugar is too high for a long time, it will cause renal arteriosclerosis, damage the kidneys and cause kidney failure. Therefore, diabetic patients and patients with hypertension should be cautious in diet, low sugar, low fat and low protein. ·Careful use of drugs will cause abnormal excretory function after kidney damage, and more caution should be used in the use of drugs. Many drugs have nephrotoxicity. Failure to excrete after ingestion will increase kidney damage. Unfortunately: all five symptoms indicate that you have entered the stage of renal failure

These bad habits are quietly “eroding” your kidneys

There are as many as 120 million people with chronic kidney disease in my country, which means that one in every 10 adults is a chronic kidney disease patient. Because there are no signs in the early stage of kidney disease, it is often easily overlooked by people. Therefore, people call kidney disease a “silent killer”. It can be seen how powerful its lethality is, it can harm your health invisible. Among them, in the early stage of kidney disease, as long as you observe it, you can also find its traces. For example, loss of appetite, fatigue and fatigue, swelling of the eyelids in the morning, foam in the urine, etc., these signal lights are reminding you that your “kidney” is already experiencing problems and should be checked and treated in time. Many people want to know, how to prevent kidney disease in life? How to kill kidney disease in the budding period? Next, let’s take a look at what factors can cause kidney disease. 1. In terms of size, bacteria and viruses are “forty to two pounds” for the human body, which will cause people to catch a cold and affect their work efficiency. Bacteria and viruses acting on the kidney unit can be described as “half a catty to eight two”. The result after the PK is not just that the kidney “worker” has a cold, it may be permanently lost “work ability” after being destroyed, which will affect the future work efficiency of the entire kidney “factory”. 2. The living standard of food is constantly improving, disrupting our original diet structure, more chicken, duck and fish meat on the table, less and less grains. Did you know that while our mouth is enjoying delicious food, our kidneys are experiencing the “catastrophe” of overwork? When the content of sugar, fat, and protein in the blood increases, the kidneys must bear a greater workload, and the kidney “workers” also have fatigue limits. No one knows when it will be the last to “break down” the kidneys. A bite of “gourmet food”, so for your own health, you should properly give the kidney a holiday. The toxicity of food additives to kidney “workers” has also been common in recent years. Most of these toxic substances will cause kidney “workers” to permanently lose their ability to work, causing irreversible damage to the kidneys and “uremia”. Pesticide residues in vegetables are relatively easy to remove if soaked for a long time, which is another benefit of eating vegetables. 3. Most of the medicines are detoxified by the liver first and then excreted by the kidneys. Therefore, the kidneys, like the liver, are susceptible to organ poisoning and are susceptible to damage. Commonly used drugs that can cause kidney damage are antibiotics and other chemotherapeutic drugs, non-steroidal anti-inflammatory analgesics, antiepileptic drugs, tumor chemotherapy drugs, various angiographic agents, metals and their adhesives. Therefore, be careful of kidney “workers” poisoning when treating diseases. The most headache for doctors in treating diseases is patients with liver and kidney problems. 4. Allergic elements and radioactive substances will also affect the kidney function. Starting from the theory of Chinese medicine, the causes of kidney disease are nothing more than internal and external factors. There are three internal causes: one is the imbalance of yin, yang, qi and blood of the kidney, which leads to abnormal kidney function. The other is “long-term disease and kidney”, and other diseases of the internal organs involve the kidney. , “Fear of injuring the kidney”, fear of qi, kidney qi solid photography dysfunction. External cause intrusion must be based on internal cause imbalance, that is, the “Inner Canon” says “the place of evil, its qi must be weak”, which means that since external evil can invade, it must be that the body’s righteousness is already insufficient, and the lack of righteousness is right Qi deficiency. For this reason, internal disorders must be the main cause of kidney disease. 5. Insufficient drinking water. Many people find this unbelievable. But you know that water is the source of life, and the human body is actually a body of water. Traditional Chinese medicine says “Kidney is water dirty”, so the kidney often suffers from kidney deficiency due to insufficient drinking water. The famous assertion of the Ziyin School says that “yin is often insufficient and yang is more than normal”. Often in the early stages of kidney disease, symptoms of yin deficiency and yang are caused by lack of water in the body. For this reason, the induction of kidney disease should not be ignored. It can be seen from this that the kidney is very fragile, and you must pay more attention to protecting your kidney in life. In order to avoid unnecessary disasters to the kidney, we need to know the various manifestations of the kidney when it is abnormal, and only in this way can we avoid greater harm. When the following symptoms appear in your body, you must be vigilant. 1. The most basic success of a weak child’s kidney is to produce urine, and to expel certain wastes and poisons metabolized in the body from the body wind. If there is a problem, it is difficult for waste to be excreted from urine

How to treat nephrotic syndrome? Do hormones really take forever?

Nephrotic syndrome is due to damage to the glomerular filtration membrane and changes in permeability, resulting in a group of clinical syndromes, often accompanied by low autoproteinemia, edema, and hyperlipidemia. Principles of treatment of nephrotic syndrome The drug treatment of patients with nephrotic syndrome aims to reduce or eliminate urinary protein, and pay attention to the protection of renal function. The current treatment of nephrotic syndrome is to treat hormones with cytotoxic drugs. Once an infection is found, it is immediately Use appropriate antibiotics to regulate the patient and pay attention to the protection of the kidneys. Glucocorticoids Glucocorticoids are the first-selected drugs for the treatment of nephrotic syndrome. According to the specific conditions of patients and the characteristics of pathological types, they are used individually. Glucocorticoids can be used alone or with immunosuppressive agents. Treatment with glucocorticoids should follow the principles of adequate, slow, and long-term maintenance. Immunosuppressants Immunosuppressants are mainly used in patients with glucocorticoid resistance, dependence, and frequent relapses of nephrotic syndrome. Commonly used drugs include cyclophosphamide and cyclosporin A. Cytotoxic drugs Cytotoxic drugs and hormones have a synergistic effect, at the same time with the application of hormones, can reduce the side effects of their own leukopenia. Glucocorticoid side effects Long-term application of hormone therapy can produce many side effects, such as stomach bleeding, induced infection, gout induction, increased renal dysfunction, osteoporosis, etc. Therefore, during treatment with glucocorticoids, you should quit smoking and limit alcohol, exercise properly, and Supplement calcium or active vitamin D to prevent osteoporosis. In life, we should pay attention to low-salt and low-fat diet, because higher-salt foods may increase the degree of tissue edema of the patient to a certain extent, and the intake of high-cholesterol foods will damage the kidneys of patients. Pay attention to rest and avoid strenuous exercise. It is necessary to reduce the infection factors that may exist in the usual living environment, maintain air circulation, avoid the use of nephrotoxic drugs, and seek medical treatment if you feel unwell. The treatment of nephrotic syndrome is a long-term process, and it may recover after remission, so you must have sufficient patience and confidence, do not reduce the amount of medicine or stop the medicine, and return to the clinic on time.

6 key points are not paid attention to

Kidney disease is a disease that makes patients feel very painful. Although this disease is not difficult to treat, the chance of recurrence after treatment is quite large. Repeated attacks will make most kidney patients feel helpless and anxious. We know that kidney disease is directly related to uremia. If the kidney disease recurs repeatedly, the kidney function will also be reduced accordingly, and it is likely to develop into uremia after a long time. In fact, the reason why kidney disease is prone to relapse is mainly caused by the patient’s lack of corresponding care in life. Kidney disease is not far away from uremia, and 6 key points are not taken seriously. So what kind of daily care should focus on recurrence of kidney disease? A regular diet is what we must do every day. Healthy people need a regular diet to maintain their health. Besides, they already have kidney disease, so they should pay special attention to the three meals at ordinary times. Overeating and excessive dieting are not allowed, nor can large fish and meat and wild food be consumed. In terms of diet, the principle of low salt and low protein diet must be achieved. Kidney disease is not far away from uremia. There are many patients with kidney disease who usually like to make supplements indiscriminately. They often eat some health supplements to supplement protein. In fact, excessive supplementation will cause certain damage to kidney function. Ingesting too many supplements will increase the burden on the kidneys, but will cause kidney disease. ‘S condition is more serious. There are many families who have family medicines, and these medicines are bought at pharmacies by themselves. They are not used under the guidance of doctors. Many patients with kidney disease look for medicines when they are sick, especially when they have a cold. Take the same type of medicine together, so the random use of medicine can easily lead to more serious illness and relapse. The active substances contained in beverages such as strong tea and coffee will cause blood pressure to rise, which is not conducive to the stability of kidney disease, so it is best for patients with kidney disease to drink these beverages in peacetime. Overnight foods are prone to chemical reactions and will form harmful substances, which will increase the burden on the liver and kidneys. Eating too many insulated foods will cause the decline of kidney function, and it is likely to enter the uremia period in advance. In order to ensure adequate sleep time, reduce the intensity of work as much as possible, especially in the case of uremic symptoms, timely treatment, and bed rest. Nephropathy patients must maintain a good state of mind, do not be too pessimistic and negative, because modern medical science has been quite developed, even if it has reached the uremia period, it can be treated by kidney transplantation or dialysis, and it can completely restore normal life and Work, and it will be better in the future, so patients must establish confidence in treatment and maintain an optimistic attitude. Reminder: Repeated episodes of kidney disease are indeed a matter of concern to patients. Repeated episodes are likely to develop into uremia, which will be more difficult to treat, and it will require a lot of treatment costs and treatment time. . Because of this, patients with kidney disease must pay attention to the treatment and daily care of relapsed kidney disease. At this time, hurry up treatment and maintain correct daily care to cooperate with treatment, you can reduce the risk of developing uremia.

Ten people and nine kidney diseases: For people with kidney disease, 3 precursors will “inform” in advance

Among the middle-aged people, they often hear their ridicule: Is your kidney okay? Actually, if you really have kidney disease, you can’t tell a joke. Ten people and nine kidney diseases: people with kidney disease, 3 precursors will be “informed” in advance. According to epidemiological research data, the incidence of chronic kidney disease in China is 10.8%, while the incidence of uremia (end-stage renal failure) is 300-400 million people. It can be seen that kidney disease is constantly threatening our health. So, what are the causes of people suffering from kidney disease? Ten people and nine kidney diseases: people with kidney disease, 3 precursors will “inform” the cause of nephropathy one: long-term holding urine I believe everyone will have the experience of holding urine, occasionally holding urine once or twice has little effect on the body, but often holding back Urine will seriously damage the kidneys and increase the burden on the kidneys. It is very easy to cause kidney problems in a long time. Two causes of nephropathy: Most patients with general nephritis have a history of pharyngitis, acute tonsillitis or severe cold. If a person has inflammation or infection, it is very likely to cause a disorder of the immune system. If the control is not timely and the disease progresses, it may damage the kidneys and induce nephritis. Ten people and nine kidney diseases: people with kidney disease, three precursors will “inform” the cause of nephropathy in advance three: privately taking drugs indiscriminately in daily life, cases of drug-induced kidney damage caused by taking drugs indiscriminately are not uncommon. As the saying goes: medicine is threefold poison. Especially for some patients with chronic diseases such as high blood pressure, diabetes, and high blood fat, taking drugs indiscriminately may damage the kidneys and cause drug-induced kidney damage. Four causes of nephropathy: regular drinking and long-term drinking not only hurts the liver but also the kidneys. This is mainly because the kidney is the most important metabolic organ of the human body. When a person consumes a large amount of alcohol, he needs to undergo kidney metabolism, which undoubtedly increases the burden on the kidneys. In addition, long-term heavy drinking leads to a significant increase in occult blood acid, thereby forming uric acid polycystic kidney stones, which can cause kidney obstruction and damage to the kidneys. Ten people and nine kidney diseases: For people with kidney disease, the three precursors will “inform” in advance that the emergence of kidney disease will undoubtedly cause great harm to people’s health, so how should people discover the existence of kidney disease as soon as possible? If you have the following symptoms of kidney disease, then you have to pay attention! (1) Edema is general. Under normal circumstances, people’s eyelids or face appear edema in the morning, and then disappear in the afternoon. However, they will edema after fatigue. Once the rest is subsided, it will often disappear. This situation is most likely to be related to kidney disease. related. Ten people and nine kidney diseases: For people with kidney disease, the 3 precursors will “inform” in advance (2) Excessive or too small urine volume Generally speaking, it is normal for a person to excrete 1500ml of urine per day. If a person is not affected by external factors, such as not drinking too little water, sweating, fever, diarrhea, etc., a sudden decrease in urine output is an abnormal condition. If a person’s daily urine volume exceeds 2500ml, it is most likely related to kidney disease. (3) Urine has foam and does not disappear for a long time. If people have foam when urinating and do not disappear for a long time, it is necessary to consider whether it is proteinuria, that is, excessive protein excretion in urine. At this time, it is very likely that there is a problem with the kidneys. You should seek medical advice in a timely manner to check your urine routine to avoid kidney disease. Ten people and nine kidney diseases: For people with kidney disease, the three precursors will “inform” in advance that in addition to self-checking the symptoms of kidney disease, regular inspection is also very important. It is best for normal people to have a routine urine test once a year, and if necessary, to perform b-ultrasound and renal function tests; those with diabetes and hypertension, it is best to check urine microalbumin once every six months to monitor the progress of the disease and actively receive standardized treatment . If the urine test shows abnormal indicators such as urinary protein and red blood cells, you should immediately consult a nephrologist for further diagnosis.

Can patients with uremia and kidney failure have children? Can you think about your child?

It is the common wish of every couple to have children, but the occurrence of disease makes them have to retreat. Nowadays, many families have no children because of the disease, and uremic patients are one of them. When it comes to uremia, many patients will feel fear, because when they mention uremia, they often think of death as an incurable disease. Many young patients are also worried: can they have children after they have uremia? Let’s take a look at this problem together. Usually, female uremia nephropathy affects sexual function and fertility, therefore, the ability to fertility during pregnancy will be reduced, even if pregnant, it is easy to miscarriage or premature delivery. Under normal circumstances, uremic nephropathy is not recommended for fertility. After dialysis, more than 99% of female patients will lose fertility, because for uremic nephropathy, due to the accumulation of toxins in the body, its metabolic function is already very good Weakness, if combined with the burden of a fetus, is equivalent to doubling the risk of the original complication of uremia, and hypertension, anemia, cerebrovascular accidents and other hazards may occur at any time. For uremia nephropathy, it is not recommended to have children, because uremia is different from other conditions. If more serious complications occur during pregnancy, it will be life-threatening for uremia patients and children, so uremia Patients with illness need to be cautious! Be cautious! Be cautious! Say important things three times.