Will localized vitiligo spread? How to cure localized vitiligo?

The symptoms of localized vitiligo are usually not serious. Vitiligo is limited to a certain part of the body, and the number is relatively small, and the impact on the patient is not great. Therefore, many people will ignore the treatment, and some patients may even feel that there is no treatment at all. Necessary. You may not know that the condition of vitiligo is not stable. If localized vitiligo is not controlled effectively, it may develop into sporadic or even generalized vitiligo. Not only will the difficulty of treatment increase, but the harm it will bring is also unpredictable. . So everyone should also pay attention to the treatment of localized vitiligo. How to cure localized vitiligo? First, early detection and early treatment is the key to the treatment of vitiligo, the same is true for localized vitiligo. If you have confirmed that the white spots on your skin are localized vitiligo, you should receive a formal and comprehensive examination as soon as possible to understand the specific cause of your illness. Professional doctors will work out a comprehensive symptomatic treatment plan based on the actual disease. 2. Cooperate with localized vitiligo. Although the treatment is relatively less difficult, there are strict regulations on the treatment and the use of drugs during the treatment process. Patients should follow the doctor’s advice and actively cooperate with the treatment. Do not modify the treatment plan or change the treatment drugs at will, and do daily nursing work according to the doctor’s guidance. 3. The treatment process of relaxing vitiligo may be a little longer. Everyone should be psychologically prepared when receiving treatment. Don’t be overly nervous, and don’t be afraid that your disease won’t be cured because you don’t get the treatment effect you want in a short time. it is good. In the process of treatment, you must maintain a positive and optimistic attitude, learn to divert your attention from the disease, and relax. 4. Consolidation Many people have such a misunderstanding in the treatment of diseases. When they find that their condition gradually recovers, they will stop the treatment according to their own ideas, thinking that the rest is the process of slow recovery. For vitiligo, a disease that is relatively stubborn and prone to recurrence, this is a very dangerous approach. Without a later consolidation treatment, the condition is easy to recur, and it will be more stubborn and difficult to treat.

Is there always pulmonary fibrosis with interstitial lung disease? How to judge the severity of pulmonary fibrosis

Pulmonary fibrosis includes two conditions, one is limited lung fibrosis, and the other is extensive pulmonary fibrosis. Whether the pulmonary fibropathy is serious or not, it depends on its clinical manifestations and the extent of the lesion on chest X-ray CT. Localized fibrous lesions The localized fibrous lesions are equivalent to a kind of scar. The scars on the skin are mostly caused by trauma, while the scars on the lungs are mostly caused by infection, especially tuberculosis infection. After infection, local cell necrosis is eliminated. Later, in order to fill the vacancy left by necrosis, surrounding fibroblasts are mobilized to secrete collagen fibers into the vacancy. These collagen fibers are the cause of the formation of fibrous foci. Localized fibrous foci have little effect on lung function, and basically do not cause significant decline in lung function. If the lung CT shows only a few fibrous lesions and the patient has no clinical symptoms such as dyspnea, this situation is not serious and does not require special treatment. Localized fibrous foci are in fact a scarring change, generally unchanged for life, there is no possibility of aggravation in the short term, and there is no drug to eliminate it. Extensive pulmonary fibrosis There are many causes of pulmonary fibrosis, such as various autoimmune diseases, such as Sjogren’s syndrome, systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, etc., which can affect the lungs and cause interstitial Pulmonary disease, severe cases will have pulmonary fibrosis. Bleomycin, gemcitabine, gefitinib and other drugs may cause pulmonary fibrosis; the pesticide paraquat can cause lung fibrosis in a short period of time. In addition, large-scale lung radiotherapy (lymphoma, lung cancer) may cause Pulmonary Fibrosis. One of the more common and serious is idiopathic pulmonary interstitial fibrosis, which is the most common disease of unexplained pulmonary interstitial diseases. The human lungs are originally very elastic, and they perform ventilation and ventilation functions. When fibrosis occurs, the elasticity decreases, and the lungs are like an iron barrel, and people cannot breathe normally. The clinical manifestations of extensive pulmonary fibrosis are progressive dyspnea, accompanied by irritating cough. The condition often continues to progress. The initial stage is active, climbing stairs, and gradually develops into a calm state of asthma. Some patients have insomnia due to long-term hypoxia. Lung function is extremely poor, and many patients still feel that they don’t have enough air even when they are inhaling oxygen. Such patients have low immunity and are prone to infections in their lungs, and eventually die of respiratory failure and secondary lung infections. This fibrotic lesion, CT characteristic manifestations are mainly grid-like and ground glass lesions or honeycomb-like changes and obvious peripheral near pleura. The main consequence of pulmonary fibrosis is hypoxia, and patients will gradually hold their breath and feel uncomfortable. Idiopathic pulmonary fibrosis was once called “lung cancer that is not lung cancer”. The quality of life of patients is poor and the survival time is limited. Treatment includes non-drug therapy, oxygen inhalation (home oxygen therapy), mechanical ventilation with non-invasive ventilator, and pulmonary rehabilitation therapy. In terms of drug treatment, the two internationally recognized drugs are pirfenidone and nintedanib, which can delay the course of the disease and reduce the incidence of acute exacerbations. But these two drugs are relatively expensive, and nintedanib is still not included in the medical insurance list.