Wang Hongxia, chief physician of the Department of Nephrology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, graduated from Beijing University of Chinese Medicine in 1995 and studied at Xiyuan Hospital of China Academy of Chinese Medical Sciences from 1998 to 2001. He studied under Professor Nie Lifang, a famous Chinese medicine nephropathy expert, and obtained a master’s degree in internal medicine of Chinese medicine. Good at treating acute and chronic nephritis, nephrotic syndrome, IgA nephropathy, proteinuria, hematuria, membranous nephropathy, focal segmental glomerulosclerosis, renal failure, diabetic nephropathy, purpura nephritis, lupus nephritis, hepatitis B virus-related nephritis, Gouty nephropathy, hypertension and kidney damage, etc. As life gets better and better, the population of “wealthy diseases” in our country is increasing day by day. Among them, the most representative ones are the new metabolic diseases “gout” and “hyperuricemia”. In 2017, the number of patients with hyperuricemia in my country was as high as 170 million, of which more than 80 million were gout patients, which was increasing rapidly at an annual growth rate of 9.7%. It is estimated that in 2020, the number of people with gout in the country will reach 100 million. Among them, drinkers belong to the hardest-hit areas. It was reported some time ago that gout patients can drink a small amount of red wine, which seems to have opened a window to the “gentle drinkers”. But immediately, the painful lesson was immediately corrected. Anyway, drinking red wine can also induce gout. So even a small amount of alcohol will increase the synthesis of uric acid in the body. If you drink a little more alcohol, it will also increase the amount of lactic acid in the body. The increased lactic acid will compete with uric acid for excretion from the kidneys, which will increase the excretion of lactic acid by the kidneys and decrease the uric acid, thereby further increasing the blood uric acid content and increasing the blood uric acid level. , May eventually induce an acute attack of gout. So don’t care about wine! Beer, liquor, and red wine all increase the risk of acute attacks of gout.
①Avoid high-purine foods: animal liver (such as liver, kidney, brain, etc.), pig intestines, thick gravy, seafood foods, and vegetable bean sprouts, soybean sprouts, asparagus, seaweed, shiitake mushrooms, wild mushrooms, etc. are all high Purine ②Avoid drinking: Alcohol will be metabolized into lactic acid in the body and affect the excretion of uric acid in the kidneys. At the same time, alcohol itself will promote the decomposition of ATP to produce uric acid. Therefore, patients must abstain from alcohol. ③Drink more water: Drink more than 2,000ml of water a day to increase urine output To facilitate the excretion of uric acid, it is best to drink water between meals and in the evening and early morning. ④Reasonable exercise: The lactic acid produced by strenuous exercise can inhibit the excretion of uric acid in the renal tubules and increase the blood uric acid. Exercise should be slow. ⑤Avoid cold and fatigue: Overwork from cold can make people’s autonomic nervous regulation disorder, causing blood vessels on the body surface and internal organs to constrict, and vasoconstriction reduces the excretion of uric acid.
With the continuous improvement of living standards, gout, a health problem formerly known as the “affair of wealth”, is plaguing people, becoming the “fourth highest” after the “three highs” of hypertension, hyperglycemia and hyperlipidemia. Gout is generally caused by high uric acid. Many doctors also recommend that patients with gout and hyperuricemia should exercise some to help control the condition. Which types of exercise are particularly suitable for patients with hyperuricemia and gout? Yoga Yoga movements are relatively gentle, and can rotate various joints, stretch ligaments, strengthen tendons, thereby protecting joints. For gout patients with high uric acid, it avoids the possibility of joint damage caused by severe impact. Friends with high uric acid can do yoga appropriately, which can protect the joints and relieve the mood. Swimming Swimming is a very good aerobic exercise. Swimming has an important regulatory effect on promoting blood circulation, enhancing heart and lung function, reducing fat and weight, rebuilding body shape, improving body metabolism, and controlling insulin resistance. The knots are not suitable for running friends. The buoyancy during swimming makes the joints less impact, which is also one of the most suitable exercise methods. Bicycles consume a lot of calories, and long-term persistence can reduce weight. When pedaling a bicycle, you need to pay attention to the intensity of exercise and gradually cultivate your body’s endurance. When jogging, because the frequency is not fast, the impact on the joints is small, and it is also an effective way to lose weight for patients with gout. Due to the condition of the disease, patients with gout and hyperuricemia must follow the following principles when exercising: 1. Do not do high-intensity anaerobic exercise. Patients with gout and high uric acid do not perform high-intensity anaerobic exercise for fitness. The high intensity of exercise will lead to hypoxia in the muscle tissue and metabolize glucose into lactic acid in the body. If lactic acid cannot be decomposed into carbon dioxide and water in a short time, it will cause the accumulation of lactic acid. This is why muscle soreness will appear after exercise, which is actually a manifestation of lactic acid accumulation. The lactic acid accumulated in the body will eventually be excreted by the body, but when the kidneys excrete lactic acid, it will affect the excretion of uric acid, leading to an increase in uric acid. 2. Don’t exercise for a long time In the remission period of gout, you can exercise, but you must master the correct method during the exercise, otherwise it will cause damage to the joints. Each exercise should control the time, do not exercise for a long time, exercise can accelerate the body’s metabolism, beneficial to uric acid excretion, but always exercise for a long time, will cause excessive sweating and a large loss of body water, which will lead to uric acid concentration. It is important to control the duration of each exercise. 3. Replenishing water in time for exercise and fitness cannot avoid sweating, but sweat does not have the effect of excretion of uric acid. For patients with gout and hyperuricemia, in addition to controlling exercise intensity and exercise duration to reduce the loss of body water caused by exercise , Also pay attention to replenish water in time. Timely hydration can dilute the concentration of uric acid in the blood, reduce the risk of causing exercise gout, and supplementing water can also help further excretion of uric acid. 4. To exercise, use drugs reasonably. A reasonable amount of exercise is helpful for the excretion of uric acid. However, patients with gout and hyperuricemia also need to take the medication on time and in the amount during the process of persisting in exercise. If the medication is stopped at will, it will cause the disease to worsen. Some people think that exercise is omnipotent, as long as you exercise, your body will get better, and they always hear that drugs have side effects on the body, and if you don’t take it, you don’t take it. In fact, this idea is quite wrong. Although exercise helps the body to excrete uric acid, failure to take the medication on time when the uric acid is already high will cause the uric acid concentration to be unable to be effectively controlled, and there is a risk of recurrence of gout at any time, even if there is no In patients with symptomatic hyperuricemia, failure to take the medication on time and in the correct amount may cause harm to various organs of the body. Therefore, if you want to exercise, you must take medication as prescribed by your doctor.
First, patients with gout should avoid taking drugs to reduce uric acid excretion. Such as diuretics, aspirin, immunosuppressants (such as azathioprine, methotrexate, penicillamine, tripterygium glycosides), etc., because the above drugs can aggravate hyperuricemia, cause gout attacks, and accelerate gout The formation of nodules. Second, gout patients should avoid high-purine foods. Such as animal organs, bone marrow, sardines, anchovies, oysters, clams, crabs, thick broth, and bacteria and algae are high-purine foods that can induce acute attacks of gout and should be avoided. Third, patients with gout should avoid alcohol. Because ethanol metabolism will increase the blood lactic acid concentration, lactic acid can inhibit the kidneys and the excretion of uric acid. If the blood lactic acid level is higher than 20-25mg/dl for a long time, the excretion of uric acid by the kidneys will be significantly reduced. . Beer is also high in purines, so alcohol must be strictly abstained to prevent gout attacks. Fourth, patients with gout should avoid obesity. Because obesity can cause gout attacks, obesity not only aggravates hyperlipidemia, hypertension, coronary heart disease and diabetes, but also increases blood uric acid. Therefore, obese people should eat less and reduce their daily caloric intake by 10% to 15% compared with normal people to reduce their weight.
Patients with aplastic anemia usually have low immunity and relatively high physical energy consumption during treatment. Therefore, many patients choose to exercise to strengthen their physical fitness in order to achieve better treatment effects. So how can aplastic anemia patients exercise safely and effectively? Aplastic anemia patients should avoid strong confrontational exercises. When the human body exercises a lot, its own sweat will also be excreted in a large amount, which will lead to the loss of iron element, and iron is the basic substance of human blood production. If long-term iron deficiency will cause hematopoietic dysfunction, it can be caused by Too much iron loss causes iron deficiency anemia. Secondly, patients with aplastic anemia should exercise moderately. During exercise, muscle tissue consumes more protein, and visceral hypoxia leads to the filtration of red blood cells, which is also a predisposing factor for exercise anemia. Once excessive exercise will cause red blood cells to break, the main pathology of aplastic anemia is pancytopenia. And strenuous exercise will cause the body to overload operation. For example, during strenuous exercise, the body will produce a large amount of metabolites-lactic acid. A large amount of lactic acid accumulates in the body. When the concentration of lactic acid exceeds a certain amount, the PH (pH) value in the blood will decrease. As a result, the destruction of red blood cells and the decomposition of hemoglobin are accelerated, resulting in a decrease in the number of red blood cells in the blood and a decrease in hemoglobin. Cause anemia. It can be seen that only moderate exercise and moderate exercise are beneficial to patients with aplastic anemia. Otherwise, it will not be effective, it will aggravate the condition of aplastic anemia, make the symptoms of anemia more obvious, and it will be useless for treatment. For more patient communication and help, please follow the WeChat public account [Aplastic Anemia] skg120
Related dermatology experts said that skin allergies are one of the most common skin diseases. There are many reasons for skin allergies. For skin allergies, many friends will choose to apply ointment to treat. So, the following is to introduce what ointment is best for skin allergies in Chongqing? is a skin chemical test, including lactic acid test, sodium lauryl sulfate test, chloroform-methanol mixed test, dimethyl sulfoxide test, acetamide test, Water wash challenge test, capsaicin test. There are two main methods of lactic acid test: (1) 10% lactic acid solution is wiped on the nasolabial fold and cheeks with a cotton swab at room temperature. (2) Subjects are required to be in a 42°C room with a relative humidity of 80% Fully perspiration, and then apply 5% lactic acid solution to the nasolabial folds and cheeks. Pain was measured on a 4-point scale for 2 minutes and a half and 5 minutes. It is worth noting that individuals who test positive are not necessarily sensitive skin. Through biomedical engineering, biophysical parameters are measured using non-invasive techniques to evaluate small changes in the skin, such as skin moisture evaporation measuring instrument is used to measure skin, skin dehydration, silicone replication and scale measuring instrument to evaluate skin 2D or 3D Surface structure, skin color spectrometer to measure skin color, laser Doppler flow meter to measure skin blood flow, A-type ultrasound meter to detect the thickness of epidermis, dermis and subcutaneous tissue. Epidermal dehydration is the most typical indicator. Treatment The treatment of general sensitive skin is to avoid re-irritation first, and minimize the beauty measures such as steaming face, massage, and exfoliation. You can choose cosmetics designed for sensitive skin, which often contain vitamin B5, carboxymethyl dextran, etc. Since the skin is dry, use a moisturizing cream containing an appropriate amount of oil. For patients with severe conscious symptoms that affect daily life, oral antihistamines and local non-hormonal anti-inflammatory drugs can be used to relieve symptoms. Prevention For people with sensitive skin, use cosmetics with simple ingredients, as little or no allergens and irritants as possible. In daily skin care, adhere to three basic principles: use a mild, non-irritating cleansing milk and moisturizing cream. Keep the skin hydrated and maintain a healthy cuticle function. Supplement skin oils and strengthen the skin barrier. 1. Ointment is suitable for those with chronic inflammation and skin allergies. First of all, we must understand the characteristics of ointment. Ointment is usually made of petroleum jelly or animal fat as a base, mixed with drugs with different functions, and mixed with different concentrations to make a fine and uniform semi-solid dosage form. It has the effects of softening the skin, protecting the wound surface, moisturizing and lubricating the skin, and keeping warm. The ointment has a strong sealing effect, so it has good permeability and is easy to exert the properties of the contained drugs. It is more suitable for chronic inflammatory skin damage, such as dryness, desquamation or hypertrophy, moss-like changes, etc. 2. Cream is suitable for Various subacute and chronic skin allergies are also called emulsions, such as Dakning cream, Pikang cream, and skin lightening cream. Cream is a semi-solid dosage form formed by emulsification of oil and water. The cream has good penetration into the skin and a wide range of applications. Various subacute and chronic skin allergies can be used. Compared with ointment, cream has many advantages, such as good permeability and a cool feeling to use; low oil content, relatively clean, easy to wash off, not staining clothes; no need to bandage after application, all parts of the body be usable. 3. The solution is suitable for acute skin allergy with exudation, eczema or skin damage with small pieces of erosion and ulcers. Features: The main solution of the solution is wet compress, which has the effects of cleaning, heat dissipation, anti-inflammatory and promoting epithelial regeneration. 4. Patients can choose appropriate powders according to skin inflammation. Typical drugs: talc powder, zinc oxide powder, prickly heat powder, etc. Ingredients: fine powder of the drug, characteristics: dry, cool and reduce friction on the skin. 5. The lotion is suitable for those with acute skin allergy and no exudation. Typical medicines: calamine lotion, compound sulfur lotion, etc. Ingredients: It is made of water-insoluble powder mixed with water. Features: It has anti-itch, heat dissipation, dryness and protection effects on the skin.  . . . . What ointment is best for Chongqing’s skin allergies? I introduced it here today.
Summer evening breeze, three or five friends, beer crayfish, are you comfortable, but is this wanton? Experts suggest not to follow the trend according to your own physical condition, but take it easy! Anyone who has suffered gout knows that during the acute attack of gout, that kind of pain will feel pain after a gust of wind! It looks like a needle prick, so painful that it doubts life, and the big man can’t help but cry! However, many people heal the scars and forget the pain. They only focus on the treatment during the acute attack. When the pain is relieved, they return to their usual habits and habits without effective intervention. In the long run, sodium urate crystals are deposited on the joints to form gout stones. Large gout stones can affect the movement of the joints, press the nerves, make the skin thinner, or even rupture, and ooze crystals like chalk shavings. The wounds will not heal after infection. Very ugly, and the joints become stiff. Can gout patients exercise? Will exercise increase gout? The answer is no, life is movement, and it is also suitable for gout patients. However, we must pay attention to the method. After strenuous exercise, a large amount of lactic acid is produced, and lactic acid will inhibit the excretion of uric acid by the kidneys, further increase the level of uric acid in the body, and induce gout attacks. It is recommended that patients with gout do moderate, low-intensity aerobic exercise, such as brisk walking, cycling, swimming, jogging, tai chi, etc., not only to exercise and enhance physical fitness, but also to avoid the rapid production of lactic acid. Some patients will ask, I like to play basketball, can’t I play in the future? In fact, it depends on the actual situation. If your opponent has a high level and runs the whole game, it will definitely not work if you are exhausted and sore all over. If it is a half-time run, throwing blue, the intensity is small, it is also possible to pay attention to replenishment during sports. Therefore, exercise depends not only on the type, but also on the intensity. The specific adjustment is based on the situation that your body bears. It not only takes into account your hobbies, but also avoids gout attacks. Why not do it! Get moving now!
& nbsp. & nbsp. & nbsp. “High Uric Acid Health Club Patient Counseling” recently, there have always been patients who mentioned that gout has recurred frequently, and the pain is painful every time. Even if the boy has tears, it is often painful at home. Was crying out loud, and this patient found out that according to our consultation, he would drink a lot of alcohol in the long-term life because of work and entertainment, and we all know that alcohol is a taboo for gout patients because alcohol enters In the human body, it needs to be metabolized in liver tissues, which will make a lot of use of the water in the blood, increase the concentration of uric acid in the blood, and cause the uric acid in the blood to enter the tissue to form crystals, which aggravates the symptoms. In addition to the purine that is eaten, it will be metabolized to produce uric acid. The body’s own metabolism produces a large proportion of uric acid. Alcohol will increase the uric acid produced by the body’s metabolism. After alcohol enters the body, it will be metabolized to produce lactic acid. The mechanism of excretion of lactic acid and uric acid in the human body is similar. Increased lactic acid will affect the excretion of uric acid in the kidneys, resulting in increased blood uric acid levels. one. So in addition to the reasons for drinking, what other factors will cause the increase in uric acid fluctuations, causing repeated attacks of gout and pain? First: lifestyle habits have a greater impact. High purine diet, drinking, and involvement are related. According to clinical data comparison, according to different ages, uric acid levels, and gender, among the clear incentives, men have the highest 3 purine diets, drinking, and fatigue, and women High purine diet, fatigue and cold are the top three. Conclusion The causes of acute gout attacks include high-purine diet, alcohol consumption, cold, fatigue, mood swings, high-fat diet, trauma and infection, among which are the most important causes. Therefore, in terms of living habits. Both men and women should pay attention to the intake of a high-purine diet. Women also need to keep warm to avoid the cold, and also need to pay attention to rest. 2. Taking drugs that cause relapses such as hydrochlorothiazide, salicylates (eg, aspirin), pyrazinamide (alias: carbamoylpyrazine, pyrazincarboxamide, isonicotinic acid amide), etc., can cause reduced excretion of uric acid, thus Secondary gout. 3. Reduced excretion of uric acid by the kidneys Uric acid is mainly excreted by the kidneys and intestines, and the renal route is the main route of uric acid excretion. There is a decrease in renal excretion of uric acid. Reduced uric acid excretion can cause gout. It is also essential for the investigation of kidney diseases. 4. Other diseases and diseases such as excessive destructive exercise cells, such as hemolysis, burns, trauma, chemotherapy, radiotherapy, too little or too much exercise, can cause excessive production of uric acid in the body, and then Gout appears, if there is no above disease, then you must pay attention to sports. For gout patients, exercise is a “double-edged sword.” If the amount of exercise is low, uric acid metabolism may induce gout, and excessive exercise leads to a large accumulation of lactic acid. Lactic acid will inhibit the discharge of uric acid and may also induce gout. Therefore, the amount of exercise is small or too much, which is “extremely worse” for gout patients. Therefore, for patients with gout, it is also very important to control the amount of exercise. Regarding how to treat gout and how to prevent it, welcome to chat with me privately.  Li Xinde, Miao Zhimin, Liu Yanhong, Cheng Xiaoyu, Liu Liu, Li Changgui. Analysis of the causes of 1713 acute gout attacks [J]. Shandong Medicine, 2012, 52 (18): 62-64.  Luo Xuehong. Various Incentives can cause secondary gout [N]. Health Times, 2015-09-17 (005). & Nbsp.