Shi Shurong medical words: Why do you have chronic myeloid leukemia? What should be paid attention to in treatment?

Patients with chronic myeloid leukemia and their families have a question: why do they have chronic myeloid leukemia? It is generally believed that the incidence of chronic granules is related to these factors: ionizing radiation, chemical pollution, and genetic factors. However, in the same living environment, only a few people have been diagnosed with chronic granules. What is the pathogenesis of this group of people? Director Shi Shurong consulted WeChat zkxk9999 slow granulogenesis: non-genetic, mostly chromosomal variation. In previous research, it has been found that chronic myeloid leukemia is caused by the translocation and exchange of the 9th and 22nd pair of chromosome end gene loci in humans. The formation of a new bcr-abl fusion gene, encoded into a specific protein, a tyrosine kinase, which leads to disease, causing a rapid rise in white blood cells and splenomegaly. The cause of the chromosomal mutation is not yet clear, but what can be determined is that it has nothing to do with inheritance. Based on the pathogenesis of slow granules, the curative effect of targeted drugs is “gratifying”. Targeting drugs for fusion genes of slow granule patients, namely tyrosine kinase inhibitors, have a clear effect and a significant effect, allowing the quality of life and survival of slow granule patients. The period has been significantly extended. However, during the treatment period, due to individual differences, it is necessary to constantly adjust the medication plan according to the patient’s condition, medication response and efficacy. Therefore, patients with slow-grain must carefully review and monitor in order to pass the medication to make the fusion gene The expression reached the expected goal, and even received withdrawal. In addition, some patients with slow-grained drugs have had various degrees of side effects during the treatment, which may even affect the final efficacy. Therefore, it is recommended that slow-grain patients can intervene in traditional Chinese medicine to increase the effectiveness and reduce toxicity! For more knowledge about chronic myeloid leukemia disease or patient help, you can pay attention to WeChat public number: mbxb120