As a method of regulating the human mental state, tourism can make people forget the troubles of disease and build the confidence of loving life through traveling in mountains and rivers and watching the cultural landscape. It can play a good role in adjusting the bad emotions caused by the disease. As long as patients with kidney disease are in stable condition and avoid fatigue, it is okay to travel, especially for patients with bad moods, travel is good. However, it is not suitable to travel when kidney disease is in an acute active period or when the condition is not stable, or when there are serious complications. In general, sufficient preparations must be done. Specifically include the following points: Arrange the itinerary reasonably. Adventurous nephrologists should pay attention. They should not travel based on their preferences. They should consider their physical conditions to see if they have the ability to do strenuous exercises, such as mountain climbing, bungee jumping, extreme cross-country, etc. . Arrange the trip, mainly time and place. ①Choose plain areas for tourism; ②Choose places with good air quality; ③Patients with high blood pressure and kidney disease, don’t go to cold and thrilling places; ④Try to choose short-distance travel routes, and the one-way time on the road should not exceed half a day. Take medicines on time. Don’t forget to call your doctor when you prepare your baggage. Ask him to consult with your itinerary about the medicines you need to bring. You can also prepare medicines for common diseases of the respiratory and digestive tracts. Consult the dosage before departure. There must be sufficient assurance that antibiotics and nephrotoxic drugs cannot be abused. You can miss one attraction, but you can’t take medicine. Taking medicine on time during travel is not a simple matter, and it is easy to forget it if you have fun. It is recommended that kidney friends put the medicine they take daily in the small grid of the medicine box, put a label on the lid, and set an alarm clock for themselves. You can also tell family and friends to help them remind themselves to prevent problems before they happen. One of the essential experiences of food tourism is the local specialties. Although eating out can’t be as comprehensive as at home, kidney friends should not be careless. Remember the doctor’s advice and try to eat in a clean place. If you can’t eat, let’s not eat. If you need less, let’s eat less. “Illness comes from the mouth” is not a lie. It is best to do your homework before enjoying the food to find out if its salt content and purine content are high? Is it spicy? And so on. If conditions permit, you can also ask restaurant waiters to not put chicken essence, monosodium glutamate, and less salt in the dishes before meals; if it is not convenient to eat with friends, you can put a bowl of hot water, and rinse the oily and salty dishes in the water first. This way the oil and salt will be reduced a lot. Nephrologists with diabetes should pay special attention to a low-sugar diet and pre-meal insulin injections; at the same time, nephrologists should also pay attention to their own diet, remember not to overeating because of delicious food. Life 1. Bring enough clothes, add or subtract clothes at any time during the journey; 2. Reduce the time spent in crowds and activities; 3. Pay attention to personal hygiene and wash hands frequently; 4. Ensure normal drinking water every day during travel; 5. When you go out to guest hotels and hostels, use the washing and cleaning appliances you bring; 6. Open windows for ventilation before going to bed at night, keep indoor air circulation, and keep the air fresh; 7. Avoid long walking and heavy exercise activities, and rest early in the evening. Recharge your energy and prepare for the next day’s activities; 8. Avoid contact with animals, especially birds, as much as possible in tourist attractions and scenic areas; 9. Kidneys with high blood pressure eat less salt, including pickled foods, when dining out; 10. Nephrologists suffering from systemic lupus and lupus nephropathy should avoid direct sunlight; 11. Purpura nephrologists with pollen allergies, stay away from flowers and plants as much as possible; 12. . If you or your travel companions find that there is a persistent and persistent high fever during travel If you have symptoms such as diarrhea, shortness of breath, or symptoms of worsening kidney disease, you must stop your travel immediately and seek medical attention. Having said so much, don’t be afraid of troubles for kidney friends. Our kidney friends “cannot afford to hurt” and must be prepared. After reading these, have the kidney friends decided to travel?
When nephrologists use drugs to treat kidney disease, they will also have corresponding requirements on their diet and lifestyle, especially in these aspects, that is, pay attention to rest, avoid fatigue and appropriate exercise (or exercise). . However, many doctors have not explained how to be well-rested or not tired, as well as the specific details of exercise (or exercise), etc. We found that some kidney friends stay at home all day long, some keep exercising every day, some continue to work overtime, and some are devoted to studying and so on. And these are often undesirable and are not conducive to the recovery of kidney disease. Among the rehabilitation exercise modes that patients with kidney disease need to do, the main one is aerobic exercise. Aerobic exercise refers to physical exercise or exercise performed by the human body under the condition of sufficient oxygen supply. That is, in the process of exercise, the oxygen inhaled by the human body is equal to the demand, reaching a physiological equilibrium state. The so-called “aerobic” refers to “aerobic exercise”. In fact, aerobic exercise requires the main muscle groups of the body to participate in addition to oxygen supplying energy. The exercise lasts relatively long and is Rhythmic. Most of our kidney diseases, as long as they are not critically ill patients, can do aerobic exercise. The nephrologist strongly recommends the following five aerobic exercise methods. 1. Taijiquan Taijiquan is a traditional Chinese boxing that is based on the dialectical concept of yin and yang as its core idea, and integrates multiple functions such as temperament maintenance, physical fitness and combat combat. Taijiquan also combines traditional Chinese medicine meridian theory, Daoyin technique, and vomiting technique to form a boxing technique that combines internal and external, soft, slow, light and flexible. Patients with kidney disease often practice Tai Chi, which is good for their physical and mental health, that is, while “fitting”, they can also “nourish the mind” to better adjust their mentality. 2. Walking on foot, namely walking and brisk walking. Walking is one of the basic activities of human beings. Originally, the entire human body structure was “designed” for walking. Walking is also recognized as the best exercise method in the world, without any cost, and no special learning is required. Needless to say the benefits of walking here. Patients with more serious kidney disease can choose to walk on the bed, and those with kidney disease who have improved or alleviated or fully recovered can choose to walk or walk quickly. According to your physical strength and feelings, you can walk more and less or walk and briskly. 3. Jogging Jogging is a moderate-intensity aerobic exercise. Compared with walking and brisk walking, jogging consumes more oxygen. Nephropathy patients who have been walking and brisk walking for a long time and are not tired can also gradually switch to jogging, which is aerobic exercise. Jogging is to run a relatively long distance at a slow or moderate pace to achieve the purpose of warming up or exercising. This type of exercise will be more conducive to the recovery of kidney disease, improve physical function and enhance disease resistance. The above three types of aerobic exercise are very suitable for the vast majority of kidney disease patients, but you still need to remember these 12 words, that is, do according to your ability, step by step, and persevere.
There are many types of nephropathy, and there are dozens of specific pathological types. The prognosis of each type of nephropathy is not necessarily different after intervention and treatment. Some types of kidney disease can maintain long-term stability of kidney function, while some kidney disease may persist and even cause renal failure. Then, in the treatment process, there are many factors that affect the different results of kidney disease, the most important and the most critical factor is the quality of the medication. If there is no correct treatment plan from the beginning, how can we talk about the long-term stability of the disease? We often say that “disease comes from the mouth.” Some bad eating habits, such as high-salt and high-protein diets, will increase the burden on the kidneys. In fact, “misuse of drugs” is more harmful to kidney function, and even fatal! Drug abuse is too bad for the kidneys! Many people are recruited. Which drugs are needed to be vigilant or even stay away from during the treatment of kidney disease? Antipyretic and analgesic (common cold medicine). How many nephrologists who usually take medicine without reading the instructions, please raise your hand! This kind of medicine is not very familiar just by looking at the name, but in fact, you may often use it. The most common type of medicine containing antipyretic and analgesic ingredients is the common cold medicine. Such as Gankang, Ganmaoling, Ganmao Capsule, Vitamin C Yinqiao Tablets, etc., these medicines all have the effect of clearing away heat and detoxification, and they are antipyretic and analgesic ingredients. However, these ingredients are clearly nephrotoxic and unfriendly to friends with kidney disease. Misuse or large amounts of them will increase the risk of kidney failure. For kidney friends who have a lot of proteinuria, hormones and immunosuppressive drugs are often used, which will cause a certain decline in their own immunity. At this time, more attention should be paid to prevent colds and other infections to avoid taking cold medicines to cause illness Aggravation. The universal “anti-inflammatory” medicine was the “anti-inflammatory medicine” that was used most for infectious diseases such as colds and fever when medicine was underdeveloped in the last world. Many people are accustomed to understanding anti-inflammatory drugs as “antibiotics.” Today we do not talk about the drug resistance caused by the indiscriminate use of antibiotics and the adverse consequences for the disease. Mainly talk about the pros and cons of kidney disease treatment. Antibiotics are also commonly used drugs for the treatment of kidney disease, mainly to deal with the immune inflammatory response in the kidney. But in fact, some antibiotics are clearly nephrotoxic: amphotericin B, neomycin, cephalosporin II, etc., which are at higher risk of kidney damage; and less damage but cannot be ignored, such as: gentamicin, kana Mycin, streptomycin, vancomycin, sulfa drugs. The application of these drugs is mainly intravenous drip. Infusion will allow the drugs to be directly transmitted through blood circulation to various parts of the body, and the risk of kidney damage will be greater and more direct. Antibiotics are nephrotoxic, as long as the dose is well controlled, most of them will not harm the kidneys. Due to the renal insufficiency and even renal failure in patients with nephropathy, the glomerular filtration rate and endogenous creatinine clearance rate decrease, the detoxification ability cannot keep up, and the misuse will cause major problems, and acute renal failure is very easy to occur. In the treatment of nephropathy with aristolochic acid, western medicine plays a major role, and some therapies of Chinese medicine can also play an auxiliary treatment function. It is mainly to regulate blood circulation, accelerate toxin metabolism, and create a good living environment for the kidneys. However, a small number of nephrologists prefer to reject traditional Chinese medicine, worrying about “Chinese medicine hurts the kidney.” There is indeed a type of Chinese medicine that is clearly nephrotoxic, and it is the well-known Chinese medicine containing aristolochic acid. For example, Qingmuxiang, Fangfangji, Asarum, Guanmutong, Tianxianteng, Du Heng, etc. are all related drugs. But all medicines have advantages and disadvantages, and have side effects and positive effects. According to the correct dosage and the compatibility of the medicine, it has a positive effect. If the medicine is used indiscriminately, it is not surprising that the medicine is not followed by the doctor. It is still recommended that everyone, if the condition recurs or worsens, don’t panic, communicate with the doctor in time about the treatment plan, and avoid blind medication.
Is the genetic probability of polycystic kidney high? Kidney disease is the number one killer that endangers our lives and health. The production of polycystic kidney disease is a disease that many people cannot avoid. Once the condition deteriorates, it will be directly linked to people’s life safety. Therefore, patients with polycystic kidney disease worry that the disease will be passed on to their family members and become a burden on the family. So, is the genetic probability of polycystic kidney high? Is the genetic probability of polycystic kidney high? The introduction is as follows: polycystic kidney disease is a genetic disease, also precisely because of the “well-known” fur and occasional individual typical examples. People have a wrong understanding of polycystic kidney disease, that is, polycystic kidney disease cannot get married, let alone have children. This puts a lot of mental stress on patients with polycystic kidney disease, causes bottomless confusion to their families, and often suffers “discrimination” from outsiders. Most polycystic kidney families have obvious heredity, and the heritability of some cystic kidneys is almost 100%. Everyone knows: If one person in a family suffers from kidney disease, then the family is already very difficult. If this disease is not treated in time, it can cause uremia. The genetic incidence of adult polycystic kidney disease is about 0.2%. It is mainly characterized by the occurrence, development and number of kidney cysts. It is often accompanied by the formation of cysts in other organs. It is more common in the liver, and can also be seen in the pancreas, ovaries, and gastrointestinal tract. . Polycystic kidney disease follows the rule of autosomal dominant inheritance: 1, the incidence rate of male and female is equal; 2, one parent has the disease, and 50% of the children get the cyst gene to get the disease. If both parents suffer from the disease, the incidence of children increases to 75% ; 3. Children who do not suffer from the disease do not carry the cyst gene, and their next generations (grandchildren) will not get the disease, that is, they will not inherit the cyst. It is asymptomatic before the onset of the disease. When the symptoms appear, the condition can develop quickly. It is one of the common causes of uremia in middle-aged people. It is also one of the most common diseases of hereditary kidney disease. Is the genetic probability of polycystic kidney high? The above is the related knowledge of the genetics of polycystic kidney. Now you have a clear analysis of the genetics of polycystic kidney! Although polycystic kidney disease has the nature of heritage, genetics does not mean that it cannot be treated. It is a wise choice to use scientific treatment methods to treat them in time! I hope that patients with polycystic kidney disease can go to regular kidney disease specialist hospitals for scientific and systematic treatment in time!
Urban women are getting busier and busy, always focusing on family business. However, women who are too stressed should stop and learn to release their pressure. If the stress cannot be relieved, it will cause great harm to the body, and the disease will find you. It is understood that there are many women with nephritis caused by high work pressure, which has brought great damage to their health, so it is very important to pay attention to health preservation in daily life. Beware of nephritis when women are stressed. Women who are under too much stress can lead to the deposition of acidic substances and affect the normal progress of metabolism. Proper adjustment of mood and self-pressure can maintain a weak alkaline physique, thereby preventing the occurrence of kidney disease. If you don’t have good habits in your daily life, do not pay attention to reasonable exercise, stay up late at night, hold back your urine, karaoke, etc., it will affect kidney function in the long term. Therefore, daily habits also have certain factors. Life is like this. We should not give Only when you feel too stressed can you keep your mood at ease, which will help you recover from your illness. What are the predisposing factors of female nephritis 1, infection factors. Many bacterial, viral, and parasitic infections can cause nephritis. Respiratory tract infections are common. Scarlet fever, purulent skin infections, etc. At the same time, infection is also one of the important reasons for the recurrence of nephritis and aggravation of renal damage. 2, high blood pressure. Hypertension is the main symptom of kidney disease, so patients with hypertension must first consider whether it is caused by kidney disease. At the same time, persistent hypertension is also one of the important reasons for worsening renal function. Active control of hypertension is a very important link in the treatment of kidney disease at all stages. 3. Genetic factors. In the past, it was generally believed that hereditary kidney diseases were rare, but in the past 20 years, with the development of science, the discovery rate of hereditary kidney diseases has increased significantly. There are currently more than 30 known. The most common ones are: hereditary nephritis, polycystic kidney disease, etc. 4. Pregnancy. Pregnancy and kidney disease can affect each other. Pregnancy increases the burden on the kidneys, which is likely to cause pathological damage to the kidneys, which promotes deterioration of renal function. Pregnancy in patients with kidney disease can lead to premature delivery, stillbirth, and increased complications during pregnancy. For patients with kidney disease who already have hypertension or renal insufficiency, pregnancy is generally not suitable. 5. Other factors. In addition to the above-mentioned hypertension and diabetes, many other systemic diseases such as systemic lupus erythematosus, hepatitis, liver cirrhosis, gout, etc. can cause secondary kidney damage.
Wang Hongxia, chief physician of the Department of Nephrology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, graduated from Beijing University of Chinese Medicine in 1995 and studied at Xiyuan Hospital of China Academy of Chinese Medical Sciences from 1998 to 2001. He studied under Professor Nie Lifang, a famous Chinese medicine nephropathy expert, and obtained a master’s degree in internal medicine of Chinese medicine. Good at treating acute and chronic nephritis, nephrotic syndrome, IgA nephropathy, proteinuria, hematuria, membranous nephropathy, focal segmental glomerulosclerosis, renal failure, diabetic nephropathy, purpura nephritis, lupus nephritis, hepatitis B virus-related nephritis, Gouty nephropathy, hypertension, kidney damage, etc. Lycium barbarum has the functions of nourishing yin and blood, nourishing liver and kidney, and benefiting savvy. When the poet Lu You was old, his eyes were dim, and he often ate wolfberries, and he also left the poem “Xue Ji Mao Tang Zhong Qing Qing, Chen Zhai a cup of wolfberry soup”. Lycium barbarum is mild in nature and sweet in taste, which is considered mild in tonic Chinese medicine. Some people keep goji berries at home for soaking in water, cooking porridge, and even chewing a few pieces a day. However, not everyone is suitable for eating wolfberry. 1. People with hot constitution have the effect of nourishing wolfberry and warming the body at the same time. Therefore, people with damp heat and phlegm resistance in the body are manifested by high blood pressure, impatient temperament, tantrums, eating a lot of meat on weekdays and the face is flushed People who have a cold, fever, inflammation, or diarrhea are best not to eat it, otherwise it will not only fail to achieve the health preservation effect, but may also worsen the condition. 2. People with weak spleen and stomach People with weak spleen and stomach and indigestion should not eat wolfberry in the hot summer, otherwise there will be a decrease in appetite, full stomach stuffiness or sour water. 3. For people with hypersexuality, wolfberry has obvious effect on nourishing the kidney and nourishing essence. There is a popular saying that “you can travel thousands of miles, don’t eat wolfberry”; modern research shows that wolfberry has the effect of excitatory nerves and can enhance sexual function. It is not suitable for people with normal hypersexuality. Taking. 4. Chinese wolfberry has higher sugar content in diabetic patients. Diabetic patients should not overdose. Lycium barbarum has the effects of protecting liver, anti-fatigue, anti-aging, etc., can enhance immunity, suitable for people with low resistance and weak body. Generally speaking, people with low immunity can eat it all year round.
The most intuitive way to judge whether the condition of a patient with kidney disease has healed or is in recovery is based on relevant laboratory inspection indicators. For example, after treatment for chronic renal failure, whether the condition has been stabilized depends mainly on indicators such as blood creatinine, urea nitrogen, glomerular filtration rate, urine protein, hemoglobin, blood pressure, blood uric acid and carbon dioxide binding capacity. If these indicators are “very good” “, it means that chronic renal failure has “improved” or “stable”. It is of course good to use laboratory indicators to determine whether the kidney disease has recovered or improved. However, relying only on hospital laboratory tests and ignoring the self-perception or physical performance of patients with kidney disease is mostly incomplete, and may even cause misjudgment. We found that, for example, in some patients with chronic renal failure, blood creatinine and other indicators are decreasing after treatment, but the patients feel very bad about themselves. It is difficult to explain that this patient’s condition is getting better. Therefore, to see whether the kidney disease is good or not, we must not only look at the examination indicators, but also make a comprehensive analysis based on the patient’s physical performance. When the kidney friend’s body has the following 5 manifestations, it means that the kidney disease is healed or is recovering. 01. Remission of edema In patients with nephropathy who originally had edema, the edema subsided after treatment, which is not achieved by strong diuretics, and there is no edema after stopping the diuretic, which means that the kidney disease is healed or is recovering. This is definitely Good thing. If patients with membranous nephropathy stop taking all diuretics, and no edema occurs, it usually means that the nephropathy has been completely relieved (clinically cured). 02. Normal urination changes from the original oliguria and anuria, or frequent urination, dysuria, or nocturia. After treatment, patients with kidney disease can urinate normally, and the daily urine output is in the normal range (the adult 24-hour urine output is 1500 -2500ml), and there is no frequent urination, dysuria, dysuria and nocturia, which means that the kidney disease is healed or is recovering. 03. Without hematuria, gross hematuria is most likely to occur in IgA nephropathy, which usually occurs within 72 hours after a cold or lung infection. Before treatment, patients with IgA nephropathy often suffer from gross hematuria. After treatment, patients with IgA nephropathy have fewer episodes of gross hematuria or no recurrence of hematuria, which can completely indicate that IgA nephropathy is improving or recovering. 04. Non-foaming Urine Urine foam increases and persists for a long time. It is mostly related to high urine protein in patients with kidney disease. The higher the urine protein, the more foam in the urine of patients with kidney disease. The high urine protein indicates that the kidney disease is more serious and is closely related to the progression of the kidney disease. After treatment, if there is almost no foam in the urine of patients with kidney disease, it means that the kidney disease has improved significantly or is recovering. 05. Getting better energy When kidney disease is just onset or during recurrence and aggravation or progression, patients often experience weakness in limbs, fatigue, shortness of breath when moving, and loss of energy. After treatment, edema subsided, urine protein decreased, plasma protein recovered, blood pressure stabilized, anemia corrected, and renal function improved, patients with kidney disease would naturally become better and better. Therefore, the energy of patients with kidney disease is getting better, which also shows that the condition is getting better.
We often say that a large amount of proteinuria in kidney disease is not a good thing, it indicates that the glomerular damage is more serious, and the overall kidney filtration function is reduced. Moreover, urine protein itself is an independent factor that affects kidney function, and it is also a major factor that affects whether uremia occurs. Since urine protein is so “fierce”, in the eyes of many people, it must be that the lower the urine protein level, the easier it is to control the disease, and the better it is to avoid kidney failure. The fact is also true. Low urine protein poses less threat to kidney function and is less difficult to treat. Is the higher the urine protein, the more difficult it is to treat? Let’s take a look at the message sent to me by a nephropathy friend a few days ago: Doctor, I diagnosed membranous nephropathy with a renal puncture. I had a large amount of proteinuria of 12g. After 1 month of treatment, the proteinuria has dropped to more than 5g. I don’t think it is very Ideally, why does our doctor say that higher urine protein is actually easier to treat? Is there any better way to lower protein faster? Membranous nephropathy is one of the typical symptoms is a large amount of proteinuria, some patients up to dozens of grams or even dozens of grams. Generally, hormones are combined with powerful immune preparations, and inflammation is inhibited quickly. Most patients will be effective in 4-6 weeks, protein will be significantly reduced, renal function damage will also be controlled, and the disease will stabilize. The patient’s urine protein dropped by nearly 7g in 1 month. The overall urine protein level dropped relatively quickly, achieving the expected therapeutic effect. Adhere to medication and appropriately adjust the medication regimen, urine protein will continue to decline, but the speed may not start to be obvious. It is already a very desirable result. This patient is very demanding of himself, but the occurrence of kidney disease starts little by little. It is definitely not enough to eat a fat man in one bite. The injury is slowly recovered, and the decline is too fast to cause overtreatment, which is counterproductive. When the urine protein leakage reaches a certain level, it indicates that there is a serious inflammation “storm” in the kidney. Then, timely use drugs including hormones, immunosuppressants and other immunosuppressive drugs. At this time, the inflammatory response is more sensitive, and the spread of inflammation can be extinguished in time. From the above point of view, the quantitative decrease in urine protein will be obvious. When it is the most serious, the condition is controlled and stabilized. When the urine protein drops to 1, 2g, it will not continue to decline. Some people have maintained this level of urine protein. The impact on kidney function is actually not great, but it still needs more attention and vigilance. The higher the urine protein, the easier it is to fall down relatively speaking, mainly for some pathological types such as membranous nephropathy, minimal changes, focal segmental glomerulosclerosis, etc. These primary nephrotic syndromes, other types of nephropathy This is not necessarily the case. Decreasing urine protein is not the ultimate goal. Maintaining stability is the most important thing to avoid recurrence. For long-term maintenance and stability below 1g, we must pay attention to these three points: if you insist on using a small amount of hormones, patients who are generally dependent or resistant to hormones will take immunosuppressant drugs. When the urine protein drops to a certain level, you can start to gradually reduce the drug. It is recommended not to be too fast. Start with half a tablet and half a tablet. If the urine protein index does not fluctuate significantly, it can be increased to 1 tablet, then 2 tablets, and successively decreased. The drug reduction cannot be accelerated suddenly. In this way, the long-acting inhibitory effect of hormones can be played more thoroughly, and it is not difficult to wait for complete withdrawal. It is not important to prevent infection and pay attention to some external factors that affect the stability of urine protein in daily life. Such as infection prevention, low-protein diet, etc., some details cannot be ignored. The effect of multi-faceted system coordination will get twice the result with half the effort. For patients whose urine protein quantification has not fallen below 1g, do not be discouraged and need to adjust the medication in time.
After the urine protein is normal, can the medication be stopped? Don’t be impulsive, it may cause a big mistake. After the urine protein treatment is normal, can the drug be stopped? Some kidney friends think that it will be fine if the urine protein index turns negative, so they don’t need to worry about it. This is a misunderstanding of many people. For most kidney diseases, the drug cannot be stopped after the urine protein is normal. If it is acute nephritis, such as nephritis caused by a common acute streptococcal infection, after about 2 weeks of anti-infection, antihypertensive, and diuretic treatment, urine protein will recover. At this time, the patient’s symptoms and indicators are normal, and the kidney pathology has basically recovered, and the drug can be stopped. However, most patients with proteinuria are chronic, not acute. Whether or not to stop the drug, you need to look at a variety of laboratory test indicators and the patient’s own clinical manifestations. The urine protein level alone is far from reaching the requirements for judging kidney disease. For example, minimal change nephropathy, urine protein can return to normal about 2 weeks after medication. But if the drug is stopped at this time, almost 100% will relapse. For example, membranous nephropathy, urine protein is usually relieved after about 4-16 weeks of medication. But if the drug is stopped at this time, the condition will come back again. Another example is IgA nephropathy. Although there are patients who discontinue the drug more quickly, the patient who discontinues the drug the fastest takes 3-6 months. Most patients require medication for 1-2 years, and some patients require longer or lifetime medication. The medication can be stopped when the urine protein is relieved. Most secondary nephropathy, such as lupus nephropathy, diabetic nephropathy, hyperuric acid nephropathy, hypertensive nephropathy, hepatitis B-related nephropathy, etc., cannot be stopped quickly. Lupus, diabetes, hypertension and other diseases require life-long treatment. Some patients even paid the price of uremia for stopping the drug, thinking that the doctor prescribed the drug for a period of time. After taking it, the urine protein test was gone and they felt all right. As a result, after a few years or more than ten years, they found kidney failure. Uremia. Is stopping the drug a good thing? In fact, most of the clinically encountered patients who need to stop drugs urgently are because of serious adverse reactions. For example, blindness and femoral head necrosis when taking hormones, severe infection and acute kidney damage when taking immunosuppressants, fatal high potassium or low blood pressure, acute renal failure when taking antihypertensive drugs, and when taking hypoglycemic drugs There has been lactic acidosis and so on. The word withdrawal is often accompanied by fear. Kidney friends shouldn’t always expect to stop the medication immediately, that is usually not a good thing. When can it be safely stopped? After the condition has stabilized. What is a stable condition? It is not the recovery of urine protein or blood creatinine, but the recovery of sensitive indicators such as cystatin C, urinary microalbumin, C-reactive protein, and immune and oxidative stress. This often requires two to three years of treatment. The “temporarily good” urine protein of patients with kidney disease does not mean “always good”. Drug reductions are common, but you should be cautious about stopping the drug. Only when our nephrologists stabilize the condition can we achieve recovery, stop the medication and restore health.
For more patient communication and help, please follow the WeChat public account [Nephropathy Association] Kidney disease is not uncommon for a long time, and the prevalence of various types of kidney disease is very high. It is obvious that this has something to do with the wrong lifestyle, such as being too tired. , Careless rest, disorder of work and rest, or poor diet, etc. In fact, many factors cause kidney disease to appear, and also give the opportunity of kidney disease. It is still necessary to be vigilant about this matter, then the impact of fever and cold on nephrotic syndrome What is there? What are the effects of colds on nephrotic syndrome? Because patients with nephrotic syndrome have weak physical fitness, the body’s cellular immunity is less than that of all normal people, and the human body’s immune function is weak. When pathogenic bacteria invade, cellular immunity not only does not swallow pathogens, The pathogenic bacteria are only temporarily tolerated. The pathogenic bacteria antigens in the human body fuse with the pathogenic bacteria themselves to form an immune complex. When the kidney functions with the blood circulation system, it will accumulate in the basement membrane of the renal tubules, which will harm the function of the kidneys. Protein outflow will eventually cause the onset of nephrotic syndrome or aggravate the condition. For patients with nephrotic syndrome, fever and cold are the key causes of recurrence and exacerbation of hematuria and proteinuria. Therefore, patients with nephrotic syndrome must pay attention to keep warm during the treatment period and after recovery to prevent the onset of fever and cold. Patients with nephrotic syndrome will reduce the body’s immunity due to low protein and the use of hormones. A fever and a cold will cause many people to feel confused, and will continue to cause some lung infections after a cold, so once If you have a cold or a fever, you should go to the outpatient clinic of the hospital to carry out routine physical examination and follow the doctor’s advice to carry out active cold treatment. In order to prevent fever and cold from causing the onset of nephrotic syndrome, some patients with nephrotic syndrome will take some fever and cold medicines on their own when they have a fever and cold. They may be temporarily effective, but in the long run, such personal behavior is indeed true. There are indeed very big shortcomings. Once a patient with nephrotic syndrome has a fever and a cold, it is very easy to cause some symptoms, such as respiratory tract infections, tonsillitis, bronchitis, etc., when choosing cold granules, antibiotics are more suitable for patients with nephrotic syndrome, whether it is in price or from Side effects are considered above.
For more patient communication and help, please follow the WeChat public account [Nephropathy Association] Stage 4 diabetic nephropathy is already in a serious stage. Stage 4 patients will have edema, always want to sleep, neck pain and other diseases. Diabetic nephropathy is one This is a long-lasting disease, and it is very easy to repeat. In fact, diabetic nephropathy is not serious in the early stage, but if the trend continues, the disease will not only intensify, but also continue to affect the health of the patient. In fact, the treatment of diabetic nephropathy must Use scientific research methods to control the condition, especially stage IV diabetic nephropathy. Scientific research and reasonable treatment methods can sustain life. What are the examination items for kidney disease? Inspection items: kidney function, urine test, electrocardiogram, urinary system color Doppler ultrasound, X-ray, blood routine examination, biochemistry related 1. Urine routine examination: Urine examination found that the patient has a transparent cast in addition to a lot of protein in the urine Or particulate matter tube shape, sometimes body fat tube shape. 2. Optional proteinuria and urine C3, FDP measurement: type I is selective proteinuria, urine C3 and FDP values are all normal, type II is non-selective proteinuria, urine C3 and FDP values usually exceed everything normal. 3. Blood biochemical examination: In addition to the reduction of total blood protein, the white/ball can be reversed, blood cholesterol type I increases, but type II does not. 4. ESR growth rate: usually 40~80Mm/h, the erythrocyte sedimentation rate growth rate is mostly parallel to the edema. 5. Protein electrophoresis: α2 or β can be significantly increased, and α1 and γ blood proteins are mostly low. 6. Renal function examination: Type Ⅰ is all normal, and type Ⅱ has different levels of abnormalities. 7. Kidney tissue examination: According to the pathophysiological observation of ultrastructure and immunity, the histological basis can be shown. What are the symptoms of kidney disease? Common symptoms: abnormal urination (oliguria, no urination, excessive urination), frequent urination, urinary urgency, inability to hold urine, urinary pain, urinary retention, urinary incontinence, low back pain (renal colic) 1. Edema: edema of different levels , It is often the first symptom of nephrotic syndrome, often insidious, and in severe cases, serosal hemorrhage often occurs. 2. Oliguria: often less than 400ml/day, or even no urine. 3. Respiratory tract infections, skin infections and other infection history often occur before the onset. 4. Frequent fatigue, anorexia, paleness, lack of energy and other symptoms. 5. Blood pressure is mostly normal, and a few have high blood pressure. Preventive measures for kidney disease 1. Adults should have routine urine examinations and kidney function once a year. If the urine shows proteinuria, elevated blood creatinine, etc., attention should be paid and a professional doctor should be checked for further examination. Key subjects of chronic kidney disease, such as the elderly over 60 years old, relatives of patients with chronic kidney disease, patients with genetic metabolic diseases such as diabetes, gout, hyperuricemia, hypertension, targeted lupus erythematosus, hepatitis, tumors, systemic infections, urethra Patients with stones, urinary tract infections, and urinary tract obstruction, those with acute renal failure, and those with reduced nephron (one kidney or part of the kidney removed), regardless of whether they have symptoms, should go to the hospital for routine urinalysis once every six months to a year. Kidney function and kidney function B ultrasound. 2. Sign up for aerobic exercise to lose weight, exercise moderately, exercise more under the sun and sweat more, which can help remove unnecessary acid from the body and prevent the occurrence of this disease. 3. Maintain a stable mood and do not have to experience great mental stress. Too much work pressure will cause the accumulation of acidic substances and affect the normal development of all metabolism. Moderate adjustment of mood and work pressure can maintain a weak alkaline physique and prevent the occurrence of this disease. Fourth, daily life should be regular.
Wang Hongxia, chief physician of the Department of Nephrology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, graduated from Beijing University of Chinese Medicine in 1995 and studied at Xiyuan Hospital of China Academy of Chinese Medical Sciences from 1998 to 2001. He studied under Professor Nie Lifang, a famous Chinese medicine nephropathy expert, and obtained a master’s degree in internal medicine of Chinese medicine. Good at treating acute and chronic nephritis, nephrotic syndrome, IgA nephropathy, proteinuria, hematuria, membranous nephropathy, focal segmental glomerulosclerosis, renal failure, diabetic nephropathy, purpura nephritis, lupus nephritis, hepatitis B virus-related nephritis, Gouty nephropathy, hypertension and kidney damage, etc. As life gets better and better, the population of “wealthy diseases” in our country is increasing day by day. Among them, the most representative ones are the new metabolic diseases “gout” and “hyperuricemia”. In 2017, the number of patients with hyperuricemia in my country was as high as 170 million, of which more than 80 million were gout patients, which was increasing rapidly at an annual growth rate of 9.7%. It is estimated that in 2020, the number of people with gout in the country will reach 100 million. Among them, drinkers belong to the hardest-hit areas. It was reported some time ago that gout patients can drink a small amount of red wine, which seems to have opened a window to the “gentle drinkers”. But immediately, the painful lesson was immediately corrected. Anyway, drinking red wine can also induce gout. So even a small amount of alcohol will increase the synthesis of uric acid in the body. If you drink a little more alcohol, it will also increase the amount of lactic acid in the body. The increased lactic acid will compete with uric acid for excretion from the kidneys, which will increase the excretion of lactic acid by the kidneys and decrease the uric acid, thereby further increasing the blood uric acid content and increasing the blood uric acid level. , May eventually induce an acute attack of gout. So don’t care about wine! Beer, liquor, and red wine all increase the risk of acute attacks of gout.
Some patients often say: I have been sick for a long time and I have forgotten what it feels like to be healthy. To judge whether the condition is good or bad, the physical feeling is one aspect, and it can also be more accurately and intuitively assessed by checking the corresponding indicators. The key to the good and bad kidney disease depends on the condition of the kidney function, so what are the indicators for testing the kidney function? Urine-related examinations are one of the necessary items to assess kidney function. Some specific urine test indicators are “alarm signs” of kidney damage. On the contrary, stable indicators are also a portrayal of improvement. The 4 major indicators in the urine test will let you know your kidney function better! Urine white blood cells, red blood cells and urine routine test sheets from top to bottom can first see the two indicators of urine white blood cells, red blood cells and related inspection indicators. The appearance of white blood cells in the urine indicates the presence of infection, that is, inflammation of the kidneys, and more than 3 red blood cells under a high-power microscope are judged as hematuria. These two indicators are often used as one of the important indicators to initially judge nephritis. During the development of kidney disease, it is also an important indicator to judge whether the condition is stable. If the white blood cells in the urine are normal in the urine test, it indicates that the renal inflammation is effectively controlled and the damage to the kidney function is reduced. The reduction of urinary red blood cells indicates that the glomerular filtration function tends to be stable, and the leakage of red blood cells is reduced. Although simple occult blood does not affect renal function. However, if urine protein and occult blood exist at the same time, it will become one of the “culprits” that accelerate renal failure, so the treatment of occult blood is also very important. Urinary microalbuminuria or urine albumin-creatinine ratio is also a marker for evaluating glomerular damage. The main test is the leakage of albumin into the urine, which is more targeted than routine urine protein. In general, the presence of a small amount of albumin requires attention to the damage of kidney function, and the index response is more sensitive. Diabetic nephropathy and hypertensive nephropathy are mainly based on the performance of urine microalbuminuria, rather than 24-hour urine protein quantification. If urinary microalbuminuria is continuously maintained below 150mg/g, it is a sign of improvement in renal function. Long-term maintenance below 30mg/g will help stabilize the condition and reduce the risk of renal failure. By the way, 24-hour urine protein quantification is a urine protein indicator that most kidney diseases will check. Compared with urine microalbuminuria, it is not as sensitive, but it is also a very important indicator of renal function. This indicator usually emphasizes more, so I won’t say more here. Next, let’s talk about an indicator that everyone is not very familiar with! Compared with the first two indicators, α1 microglobulin has not been observed and understood by many people. α1 microglobulin not only reflects the glomerular damage, but also an index to judge the degree of renal tubular damage. It is a marker of renal tubular damage. If this index can control the improvement, it means that the renal tissue units such as the glomerulus, renal tubules and renal interstitial have all improved, and the overall renal function has also stabilized. The amount of urine, especially nocturnal urine output, is also a very direct indicator for judging glomerular filtration function. For patients with renal insufficiency, urine is basically collected to observe urine output. Stable urine output is one of the signs of stable renal function, and for patients with renal failure or even uremia, if the urine output remains stable at more than 1000ml, the risk of dialysis is also very small, and there is still a possibility of improvement. Urine output is mainly divided into daytime urination and night urination. The condition of nocturia also reflects the quality of kidney function. In general, patients with kidney disease with high blood pressure and high blood sugar have excessive nocturia (more than 2 times) and low urine output (less than 1000ml), indicating poor renal function, which requires attention.
Nephrologists often leave messages saying: Doctor, my urine protein has gone from + to 3+ again, what should I do if it turns negative and relapses again? As one of the key indicators that affect the progression of kidney disease, the fluctuation of urine protein is very detrimental to the stability of renal function. So, urine protein is so easy to “change face”, what are the “culprit” factors? It mainly includes two aspects: the development of chronic kidney disease itself and the daily management of urine protein. In the development of nephropathy, the main reason is that incomplete treatment leads to repeated immune inflammation in the kidney, causing fluctuations in the condition, and then repeated urine protein. Inadequate daily management of some factors that affect urine protein can also cause fluctuations, such as failure to adhere to a low-protein diet, frequent colds and small infections, vigorous exercise, or medications that are not taken. Repeated urine protein is not terrible, as long as the inducing factors are found and corrected and improved in a targeted manner, most of them can be quickly reduced to stabilize the condition. However, when some patients have recurring proteinuria, most of them do not look for the specific factors, but the first reaction is to add medicine. If I feel that the amount of medicine is not enough, I change the medicine, and I feel that the medicine is not good. However, if the predisposing factors are not found, even if the dressing is changed or added, the urine protein is still prone to recurrence and cannot fundamentally improve the condition. How to reduce the risk of recurrence of urine protein? Doing a better job is better than just adding medicine, that is, improving immunity. Whether it is the recurrence of inflammation in the kidney, or infection and other factors, it is inseparable from the low immunity. Damage to kidney function can damage the body’s immune system, leading to a decline in disease resistance. Not only is urine protein prone to recurrence, but kidney disease is also prone to recurrence. Improve immunity, can effectively fight immune inflammation! Improving immunity, on the one hand, is to regularly check related indicators such as immune globulin. If necessary, immunoglobulin can be used. There is also the prevention of infection, especially common respiratory infections such as colds and tonsillitis. Some kidney friends can be vaccinated in advance. On the other hand, pay attention to the protection of immunity in daily life. For example, diet and nutrition, eat more high-protein, high-vitamin foods, adhere to appropriate exercise, enhance resistance, and correct some behaviors that damage immunity, such as staying up late, smoking, and drinking. Strong immunity is the basis for fighting any disease, and kidney disease should pay more attention to this. Medication alone is not necessarily effective. Immunity is a powerful “good medicine” every day.
After being sick, most people are weaker, and their faces are not very good and pale. But some kidney friends’ faces are not pale. The course of kidney disease is longer. Compared with other diseases, kidney friends often have some “faces” unique to kidney disease. On the one hand, it is affected by kidney function. After the kidney is damaged, the filtering function and detoxification function decrease, and a large number of metabolites in the blood can not be discharged in time, and the accumulation in the blood will make the face look yellow and dull, or even gradually darken. On the other hand, some index changes caused by glomerular damage and side effects after taking the medicine can also cause some obvious changes in the face. For example, eating hormones can easily cause a full moon face, and edema such as face swelling, eye swelling, and anemia, the face will not be pale, sallow and so on. Is your face getting “black” a sign of worsening kidney disease? It is generally not obvious for patients in the early stage of kidney disease. The renal function is slightly impaired, creatinine, uric acid and other indicators are not elevated, the glomerular filtration rate is normal, the blood toxin level is low, and abnormalities are not often seen. With the decline of kidney function, more toxins cannot be metabolized and deposited in the blood. Over time, they will slowly appear on the surface of the skin, and the skin will appear dark and dull. Renal failure and uremic dialysis patients are often more obvious. If the nephrologist finds that the skin becomes “black”, he should pay attention to the reexamination indicators. The key to correcting the “unsightly complexion” is to maintain the stability of kidney function and avoid further deterioration of the condition. The key to preventing kidney failure is to pay attention to these two aspects! 1. After correcting anemia in time, blood creatinine often starts to rise after renal insufficiency, which means that the level of toxins increases. At this stage, another important indicator that affects the condition is hemoglobin. Hemoglobin is an important indicator for judging whether there is anemia, which will accelerate the arrival of kidney failure. Impaired renal function can lead to a reduction in the production of a substance-erythropoietin, which stimulates the bone marrow to reduce blood production, leading to the occurrence of renal anemia. The remaining kidney function itself has ischemia and hypoxia, which promotes the reduction of blood circulation and also aggravates anemia. Patients with anemia often look pale and sallow. To prevent anemia from accelerating the failure of remaining kidney function. It must be corrected in time. In the case of decreased hemoglobin, on the one hand, erythropoietin can be injected to increase the cells that stimulate hematopoiesis until the hemoglobin condition reaches the standard. On the other hand, actively supplement iron. Although renal anemia is not iron-deficiency anemia, most patients have iron deficiency after anemia. It is necessary to supplement iron and eat more iron-containing foods such as animal blood, animal offal, lean meat, etc. 2. Pay attention to the prevention and treatment of electrolyte disorders. The kidney has the function of regulating the balance of water, acid-base and electrolyte. The early compensatory function of renal function is still strong, and only the imbalance of water and sodium appears. The electrolyte and acid-base levels in the body are still relatively stable. However, after substantial damage to renal function, glomeruli, renal tubules and renal interstitium are all damaged, and electrolyte levels will also be metabolically disordered. Electrolyte disorders are mainly manifested as changes in trace elements such as calcium, sodium, potassium, phosphorus, and magnesium. The main manifestations are hyperkalemia, calcium and phosphorus metabolism disorders, acidosis and so on. The increase of blood potassium, blood phosphorus and other indicators will also aggravate the increase of blood creatinine, uric acid, urea nitrogen and other toxin levels, which is not conducive to the metabolism of toxins. It will also cause more complications and threaten the remaining kidney function. For example, long-term hyperkalemia can cause slow heart rhythm or even sudden arrest, cause cardiovascular disease, and acidosis is more harmful. Hyperphosphatemia can increase the accumulation of skin toxins, cause skin itching, and cause bone diseases such as osteoporosis. . In the middle and late stages of nephropathy, attention should be paid to correcting electrolyte disorders, which is another key to preventing uremia.
For more patient exchanges and help, please follow the WeChat public account [Nephropathy Association] IgA nephropathy has a great impact on people’s physical and mental health, so we need to attach great importance to this disease. At the early stage of IgA nephropathy, one should pay attention to an effective and healthy diet to prevent the condition from getting worse. Patients should pay attention to the protein intake in normal times. So, what are the common problems with dietary combinations for patients with IgA nephropathy? What are the common problems with dietary combinations for IgA nephropathy? 1. Protein provision: The dietary combinations for IgAIgA nephropathy should be based on the level of kidney damage to determine the protein intake . If the history of present illness is long and the kidney function is not serious, the protein in the food does not need to be strictly limited. 2. The provision of kinetic energy: Because some patients have limited protein, carbohydrate compounds and body fat are the key sources for their energy provision. The provision of kinetic energy depends on labor efficiency and the needs of patients’ activities should be considered. 3. Control the intake of acetate: depending on whether the patient has hypertension and edema, they should be given a salt-less and salt-free diet. For severe edema and high blood pressure, the amount of acetate should be controlled within a certain range, and even given to a salt-free diet, generally low salt is appropriate. Also avoid eating other salty foods, glycogen drinks and stimulating foods. 4. Limit potassium intake: If IgA patients experience oliguria (less than 1000ml per day), then foods with high potassium content such as kelp shreds, sea vegetables, animal organs, bananas, apples, oranges, potatoes, tomatoes, winter melon, Tea leaves, light soy sauce, chicken essence, etc. need to be limited. 5. Water intake: Patients with IgAIgA nephropathy should drink plenty of water or drinks. If there are no special circumstances, such as very medical conditions, the doctor advises not to drink a lot of water. Drinking more water is a key aspect in the diet and care of IgAIgA nephropathy. Relatives can also urge the patient to drink more water. When IgAIgA nephropathy further develops into renal insufficiency and uremia, in addition to strictly limiting protein, water intake should also be strictly limited. 6. Vitamin supplementation: All IgA patients must be given adequate vitamins in their daily diet, especially vitamin C supplementation. Patients with chronic IgA nephritis may have anemia. Vitamin C supplementation can improve the digestion and absorption of iron. More foods containing vitamin b2 and folic acid should be added to correct anemia. Patients need to pay attention to the development trend of these diseases, reasonably control the sodium content, and pay attention to the reasonable supplement of vitamins. Usually, they must pay attention to some aspects to prevent tumors from appearing, and pay attention to the treatment measures to cooperate with each other to prevent kidney function. Cause a big threat and affect the lives of patients.
After the occurrence of kidney disease, many people worry that the kidney disease can be reversed or controlled? Do you have to take medicine for life? If the kidney disease slowly progresses to uremia, it must be a lifelong medication to maintain a stable condition. Of course, although some patients with kidney disease tend to be stable, for long-term considerations, in order to maintain the long-term stability of kidney function, long-term medication is needed to maintain it. At the same time, some patients were found in time and had mild pathology. After intensive intervention with drugs, their condition was completely controlled or even recovered, reaching the standard for complete drug withdrawal. In fact, the most fearful thing about kidney disease is not taking medicine for life, but not using medicine or using medicine indiscriminately. In other words, it is a good thing that kidney disease can be controlled and stabilized with drugs, but it is not terrible. However, it is a terrible thing for some nephrologists to administer or discontinue medication indiscriminately in order to recover as soon as possible. Kidney disease requires long-term medication to maintain stability, which is a test of how patients can distinguish some drugs. Careless use of these “kidney” drugs can accelerate kidney failure! 1. Proton Pump Inhibitors——Prazole Stomach Drugs When it comes to proton pump inhibitors, many people are not familiar with it, but are they familiar when it comes to prazole drugs? For example, omeprazole, lansoprazole, rabeprazole, esomeprazole, etc. are common gastric medicines for gastric acid secretion. Some patients with nephropathy have their own gastrointestinal diseases, and the accumulation of toxins after impaired kidney function can lead to poor gastrointestinal digestion. Most of these drugs are used. There are also patients who are using hormones, they will habitually use prazole drugs. But many people don’t know that these drugs may hurt the kidneys if they are used incorrectly. Studies have shown that the longer the use of prazoles, the greater the possibility of kidney injury and the greater the risk of acute renal failure. Therefore, nephrologists who take such drugs must pay attention to monitoring blood creatinine and renal function. Do not use them in a large amount, and it is better not to take them if they are unnecessary. It must be taken in strict accordance with the dosage prescribed by the doctor. 2. Chinese herbal medicine containing aristolochia, such as moxibustion, medicated bath, etc., and some drugs such as astragalus, panax notoginseng, angelica, etc. can also play a positive role in the treatment of kidney disease. The combination of traditional Chinese and western medicine can often play a more effective role in treating kidney disease, which is also the main theme at present. But no matter what kind of treatment methods and drugs, attention should be paid to the reasonable application. Some patients are often keen to find some “remedies” after the bottleneck in the treatment of their condition, instead of the treatment in the formal Chinese hospital, it increases the risk of kidney failure. Among them, there is a type of Chinese medicine that clearly hurts the kidneys and should not be tried, that is, Chinese herbal medicines containing aristolochia. This kind of medicine not only has strong nephrotoxicity, but also carcinogenicity. The more common medicines include Aristolochia, Asarum, Qingmuxiang, Guangfangji, Guanmutong, Cinnabarinus, Du Heng, Tianxianteng and so on. Kidney friends must pay attention to Chinese medicine. Long-term medication is an effective means to keep the kidney disease stable and prevent renal failure, but using or not using medication can add trouble.
During the onset of kidney disease, there is a process for the development of renal function from good to bad. Conversely, after treatment, it takes a certain time for the recovery of renal function from bad to not too bad to slowly stable. The process of improving kidney disease is the process of treatment. You may be more sensitive to signs of deterioration. However, in addition to some routinely observed indicators such as urine protein and blood creatinine, the specific measurement standards are not very clear. This can easily lead to a relapse in the treatment process without treatment. It is clearly “cured” but relapses, and even “kidney failure” occurs. In order to avoid this kind of situation, the nephrologist must be aware of these 3 points in order to maintain the long-term stability of the condition! 1. The degree of stability of renal function judges the improvement of kidney disease, often by looking at the value of urine protein, the value of blood creatinine, whether blood pressure is controlled, etc. The stability of these indicators reflects one point, that is, whether the kidney function is stable. At different stages of development of nephropathy, the kidneys are concerned about the function of different aspects. In the early stage of chronic kidney disease, there are only symptoms of urine protein and occult blood. The main consideration is the impaired renal glomerular filtration function. The treatment is mainly to combat kidney inflammation and reduce glomerular damage to stabilize the kidney filtration Rate function. In the middle and late stages of nephropathy, the kidneys have very little self-compensation function left, and indicators such as blood creatinine, uric acid, and urea nitrogen begin to rise, indicating that the kidney’s detoxification function has declined, and some excess “metabolic waste” cannot be excreted from the body. At this time, attention should be paid to the blood circulation of the kidneys and toxin metabolism. For patients in the early stage of inflammatory reaction in nephropathy, substantial damage has not yet occurred, and the glomerulus is not damaged much, and the condition can be basically kept stable. Partially sclerotic glomeruli cannot be regenerated in the middle and late stages of nephropathy, and renal function is irreversible, but most of them can remain stable. Through the decline of the corresponding indicators and the slowing down of the renal filtration rate, it can basically be determined that the condition is stable and improved. 2. The condition basically has no recurrence or fewer times. The improvement of kidney disease treatment is not only the decline of the index at that time, but also the clinical cure. Whether the condition will relapse is also a key criterion to consider whether the condition is stable. The previous patient, with renal function syndrome, was first diagnosed with urine protein 3+, 24-hour urine protein quantitative 4.5g, creatinine was normal, and renal function was not severely damaged. After hormone shock anti-immune therapy, urine protein was controlled and basically changed yin. I thought the condition was stable, but after 2 years, it relapsed again, and it was more serious. My creatinine increased to more than 300, and the renal insufficiency was in the stage. During the five years when her condition was recovered, she did not insist on medication and did not review. I don’t know when the condition will relapse and worsen. Whether the condition will relapse or worsen is not only related to treatment, but also maintenance and management in the later period. Some patients feel that the indicators have returned to normal, so they don’t need to pay more attention. However, it must be understood that kidney function can be stable, but some diseased tissues may not fully recover. Renal cells that have undergone hardening and fibrosis will leave marks in the kidney. To prevent recurrence, renal function and related indicators must be reviewed regularly and careless. 3. Basic recovery of specific symptoms of nephropathy. Impaired renal function will cause the corresponding indicators and symptoms to rise. For example, the loss of urine protein will cause renal edema, hypoproteinemia, and hyperlipidemia. Damage to the glomeruli leads to abnormal water and sodium metabolism, which can lead to increased blood pressure and cause dizziness and headaches. Most people will experience fatigue, poor appetite, and nausea in the early stages. After the condition improves, most of these symptoms can be relieved, basically the same as normal people. However, if the indicators are stable, but the corresponding symptoms are not effectively relieved, the drug cannot be stopped blindly, and the treatment still needs to be maintained for a period of time. Slowly reduce the medicine, the body adapts faster, and the relapse rate is lower in stable disease. If you have not reached these three standards, you must not blindly stop treatment, you need to adhere to standardized diagnosis and treatment.
Lao Liu is 66 years old and always keeps exercising. Two days ago, I was “walking in the rain”, and it didn’t take long for me to experience coughing, brain pain, and runny nose. Old Liu thought it was a cold, so he took some cold medicine casually. I didn’t know that this “cold” was not only bad, but also There was loss of appetite, nausea, fatigue, and swelling of both legs. Ever since, Lao Liu came to Chuan Mi for further inspection. I don’t know if I don’t check it. Lao Liu found out that he had severe hyperkalemia—a disease that could cause cardiac arrest at any time. Fortunately, Lao Liu found out in time. After 3 weeks of treatment by our doctor Chuan Mi, the condition was effectively controlled. And this is what Xiao Mi Jiner wants to say-[Acute Kidney Injury].  . Acute kidney injury is a clinical syndrome caused by the rapid decline of renal function caused by a variety of etiologies, which occurs “invisible”. It may occur in patients who do not have kidney disease, and patients who have chronic kidney disease themselves are also vulnerable. It is an acute and critical illness in kidney disease. Drug-induced kidney injury is the most common type of acute kidney injury. Drug-induced kidney injury as the saying goes: It is three points of poison. The kidney is the excretion organ of many drugs, which means that these drugs have to pass the kidney before the stomach is eaten, and they will go after the kidneys. However, our kidneys are unfamiliar with these “aliens”, and differences may arise when bragging, which affects the normal function of kidney cells. Just like Lao Liu mentioned at the beginning of the article, he thought he had a cold and just grabbed medicine, didn’t see the doctor at all, didn’t take medicine according to his condition, how could his body suffer? !  .Drug-induced renal injury refers to the adverse reactions of the kidneys to therapeutic doses of drugs and the toxic reactions that occur due to overdose or unreasonable use of drugs, which are caused by different drugs including Chinese herbal medicine, and have different clinical special diagnoses and different pathological types A group of diseases. According to data, up to 20% of acute renal failure is caused by drugs, most commonly in the elderly. The main manifestations are hematuria, proteinuria and tubular urine with abnormal urine test.  . 2. The pathological structure of the kidney is abnormal. Renal tubular epithelial cell degeneration, edema, and necrosis.  . 3. Abnormal renal function, increased blood creatinine or decreased glomerular filtration rate.  .Main classification 1, the toxicity of the drug itself. 2. Allergic reactions caused by drugs as antigens. 3. Drugs affect blood flow and cause damage.  .Don’t worry, don’t worry! Focus on getting old! The first place is none other than antibiotics! Kidney damage caused by antibiotics is the most common. For example:  . The second place will be awarded to antipyretic and analgesic drugs, which are the antipyretics and painkillers we usually talk about. Such as aspirin, acetaminophen, aminopyrine and so on.  .The third place is anti-tumor drugs. The most common ones are platinum alkylating agents, cyclophosphamide, methotrexate, and mitomycin.  .The tail of the crane is traditional Chinese medicine. For example, Guan Mi Tong, cinnabar, etc. must be used with caution.  .The conclusion is to use medicine carefully and follow the doctor’s advice! Sichuan Urology Hospital The internal medicine department of Sichuan Urology Hospital is a comprehensive department built with multiple specialties and multiple diseases. It has a strong technical force and a professional technical team. It is responsible for the clinical diagnosis and treatment of frequently-occurring and common diseases in internal medicine. scientific research. With integrated traditional Chinese and Western medicine as the diagnosis and treatment feature, it mainly covers nephropathy, respiratory, cardiovascular, digestion and other specialties, with 45 beds open. There are more than 20 medical staff, including 1 chief physician, 2 associate chief physicians, 4 attending physicians, 4 residents, including 3 master’s degree students, and 1 heir of the fifth batch of old traditional Chinese medicine experience in Sichuan Province.  . . Mainly diagnose and treat diseases 1. . Urinary system: urinary tract infection, nephritis, nephrotic syndrome, asymptomatic proteinuria, acute renal respiratory failure, chronic kidney disease, etc. 2. Respiratory system: chronic obstructive pulmonary disease (COPD), chronic pulmonary cardiopulmonary disease, respiratory failure, pulmonary infectious diseases, bronchiectasis, acute upper respiratory infection, acute and chronic tracheobronchitis, bronchial asthma , Emphysema, interstitial lung disease, pleural effusion, chronic cough, pulmonary nodular disease and lung tumors. 3. . Cardiovascular diseases: hypertension, hypertensive heart disease
People often ask if a relative in the family gets kidney disease if they will get kidney disease, or if their children will get kidney disease. Today, let’s talk to you about whether kidney disease is inherited. 01What is family gathering? Family gathering, everyone may be a little strange to this term. A certain common characteristic of a family is called family aggregation. In other words, in the same family, due to the same eating habits and living environment, multiple family members may suffer from the same disease. Therefore, what is passed from the previous generation to the next generation is not the disease itself, but under the same environmental factors. People with this genetic factor are more likely to get the disease than normal people. In this process, environmental factors play an extremely important role. effect. 02 Does nephropathy have family clustering? In fact, most kidney diseases do not have family clusters. If the father has kidney disease, it may not be passed on to the offspring. It is mainly necessary to determine the cause of the kidney disease and the specific diagnosis. If it is polycystic kidney disease or hereditary glomerular disease (Alport syndrome, Fabry disease), this type of hereditary kidney disease has family clusters and will be passed on to offspring; such as diabetic nephropathy, systemic lupus erythematosus nephropathy, high Blood pressure and nephropathy may also be related to genetic and environmental factors. However, if it is drug-induced kidney injury or occupational kidney injury, these are not family clusters. Speaking of this, many nephrologists’ associations are beginning to worry, will their family members get sick because of family clustering? In order to avoid this situation, the following 3 points should be done: • See a doctor early, diagnose the cause of the disease as soon as possible, and treat it as soon as possible; • Genetic testing should be done for kidney disease of unknown cause or suspected family inherited kidney disease; • Yes For nephrologists with family clustered kidney disease caused by environmental factors, family members should change their living environment and habits and go to the hospital for examination as soon as possible. 03 Common kidney disease screening items So, which check items should be done and which should not be done? Common examination items for kidney disease Urine routine Urine routine contains protein, occult blood (occult blood), red blood cell (high power field), glucose and ketone bodies. Note: Protein in urine routine is easily affected by diet and exercise; urine ketone body is a more dangerous signal, similar to urine sugar, which appears when the condition gets worse. Renal function includes creatinine (in general, creatinine can reflect the degree of kidney damage), urea nitrogen, uric acid, and cystatin C (a sign of kidney damage). Kidney B-ultrasound B-ultrasound can help us understand the specific size of the kidney, whether there are cysts, hydrops, stones, etc. The preferred screening method for different types of kidney disease 1. Ordinary blood test, urine test and ultrasound can simply distinguish whether there is kidney disease; 2. Screening for hereditary polycystic kidney disease, ultrasound is the first choice. Color Doppler ultrasound can diagnose polycystic liver and polycystic kidneys. If there are suspicious signs, consider doing MRI; 3. For familial clustered nephropathy (such as diabetic nephropathy, hypertensive nephropathy, etc.), urine albumin and glomerular filtration rate are preferred Check; 4, non-genetic non-familial cluster nephropathy can do urine routine. Of course not all kidney diseases are life-threatening. As long as you remember to go to a regular hospital for scientific and effective treatment, you can live a normal life. Therefore, if you have kidney disease, don’t lose your confidence and treat it actively!