Keloid recurrence/pruritus/infection, it turned out to be making trouble

In an operation this morning, I used surgical nucleotomy to remove the lesion tissue in the front chest keloid for a patient. From the excised keloid tissue, there are a lot of skin attachments such as sebaceous glands and hair follicles, and a little squeezing can see that there are sebaceous gland secretions like tofu. Many people may not know that if these skin appendages are infected, they are one of the main reasons for the recurrence of keloid scars. &nbsp. We know that acne (acne) is the main cause of keloid scars. Acne is usually caused by excessive secretion of sebaceous glands, sebaceous gland ducts are easily keratinized and blocked, and sebaceous glands can’t be secreted out. After a long time, bacterial invasion will cause them. Infection of hair follicles and sebaceous glands can cause acne. &nbsp.Usually, acne will gradually disappear and the skin will return to normal if handled properly. On the contrary, repeated inflammation and damage to the skin attachment will stimulate the skin tissue to initiate the repair mechanism. If the repair is too active, fibroblasts proliferate more, collagen is overproduced, and the balance of skin lesion repair is disturbed, and keloids will appear. The most common areas for keloid scars are also located in areas rich in sebaceous glands, such as the jaw, chest, shoulders, back, and pubic caruncle. After a keloid is formed, its deep tissue contains a large number of skin attachments such as sebaceous glands and hair follicles, which makes it difficult to remove these attachments during the scar softening needle or laser treatment. After a period of time, the sebaceous glands secrete sebum, and the inability to discharge it in time will cause sebaceous cysts. Inflammatory stimulation will make the keloids proliferate again, which is also one of the important reasons for the recurrence of keloids. In addition, when these skin appendages in the keloid are in a state of severe inflammation, it will also cause the keloid tingling, itching, infection and ulceration, causing extreme pain to the patient. This view has also been recognized by the international medical community, and similar discussions can be seen in foreign medical journals. &nbsp. For keloids with repeated sebaceous gland infections, if the internal infected skin accessory structure is not removed, they will continue to make waves inside, causing recurrence, infection ulceration, itching and tingling. Therefore, my experience is: It is best to clean the skin structure that is often repeatedly infected in keloids through surgery, and then cooperate with shallow radiotherapy to effectively reduce the recurrence rate and achieve the purpose of treating both symptoms and root causes.

What the hell, piercing your ears makes a “meat earring”?

Many people who love beauty show their personal charm by wearing earrings. Because the operation is simple, piercing can be done in many stalls and jewelry stores, but they ignore that piercing is also risky. Some people are piercing because of piercing. It also comes with a “meat earring”. What is going on? Sister, where did you buy these earrings? Miss Fang, young and beautiful, is at the age of beauty. She pierced her ears when she was in school. More than 3 years ago, I saw that many of my friends around me had multiple pierced ears and then put on beautiful earrings and studs. I felt very fashionable, and I was moved to pierce my ears again. It didn’t take long for them to pierce each earlobe in a jewelry store. However, she did not expect that this piercing would have a great impact on her future life. Soon after the piercing, Ms. Fang put on her newly bought earrings, but after a few days of wearing, the pierced ears in her left ear began to become red, swollen and itchy, which led to ulceration and infection, which eventually led to the growth of a small pimple. At first, this fleshy lump just sealed the pierced ears, Miss Fang didn’t care too much, and even thought about getting the pierced again in a few days. However, a few months later, the meat bumps grew bigger and bigger, and they continued to erode the surrounding skin. Miss Fang became anxious and started treatment. However, using a lot of externally applied scar-removing ointments did not have any effect. Instead, it stimulated the pimple to grow more rapidly, and finally formed a “meat earring” on the earlobe. This “flesh earring” made Miss Fang very bored. She didn’t dare to tie her hair every time she went out, so she could only drape it and cover it as much as possible. Once, I was asked by a stranger: “Sister, where did you buy these earrings? You have a personality!” The scene at that time made Ms. Fang very embarrassed and deeply hurt Ms. Fang’s self-esteem. It was even bigger when she returned home. Cried. Find the right way to remove the meat earrings. In fact, since that incident, Soeasy, Ms. Fang wanted to remove the meat earrings even more. She also learned from the Internet that this is actually a type of dermatofibroma-keloids. There are many girls similar to her on the Internet, all of which are caused by piercings. However, as she learns more, Miss Fang’s heart sinks. Because this disease has a very high recurrence rate, many people have recurrences after surgical resection, which causes the ear scars to grow and grow. Miss Fang hesitated, is it really impossible to remove the meaty earrings on the ears? Just when Miss Fang was at a loss for “meat earrings”, she occasionally saw my case of treating keloids on Weibo. The patient also had keloids caused by piercing her ears, and the keloids were bigger than hers. However, after treatment, the appearance of the ears was not damaged or recurred. This made Miss Fang once again see the hope of removing the “meat earrings” . After I came to the hospital, I checked and pointed out that piercing the ears is not a simple matter. In fact, the hygiene environment is very demanding. Once infection is caused, it is likely to cause keloid scars. In response to Miss Fang’s situation, I formulated a comprehensive treatment plan for her with surgical resection and SRT-100 shallow radiation. Surgical removal of keloids and repair of the appearance of the ears, while suppressing the excessive proliferation of wound fibroblasts and the recurrence of keloids by means of shallow placement, so as to achieve the purpose of treating both symptoms and root causes. After the operation, I successfully removed the keloid on Ms. Fang’s ear and performed cosmetic stitches. Judging from the photos after stitch removal, the wound healed well. After a period of recovery, it is obvious from the photos sent by Ms. Fang that the scars are healed well, and there are almost no traces of surgery. The appearance of the ears remains intact. There is no recurrence of keloids, which basically meets the expectation of treatment. Ms. Fang I am also extremely satisfied with the treatment effect. Most of the causes of ear keloids are caused by piercings in the ears, and a few are caused by trauma. At first, they are usually soybean-sized, pale pink or bright red, and are accompanied by pain and itching. Since the development trend of keloid scars has no periodicity to follow, no one of us can predict how it will change, so keloids must be cured as soon as possible. If it is not treated immediately, it will not only grow bigger, but also cause cartilage digestion and absorption and helix deformation, which will seriously affect the patient’s mental health and normal daily life.

Vitamin D cures keloids, rumors or prospects?

Many people, especially Bao Ma, are no strangers to vitamin D. Vitamin D is also called cod liver oil in daily life because it is rich in fish liver. It is a “complementary food” that babies need to supplement every day. The main role is to help calcium absorption. The vitamin D in the adult body needs to be converted into active vitamin D through the sun to play its biological role. In the research literature, there have not been extensive reports about vitamin D in the onset and treatment of scars. A research article published in the journal “JDrugsDermatol” in July 2020 shows that vitamin D also has antibacterial, anti-inflammatory, and inhibiting effects on cell tissue proliferation. The author of the paper searched PubMed for the literature on vitamin D and keloids, hypertrophic scars or burn scars, analyzed from the perspectives of molecular, epidemiology, and human clinical research, and came to the conclusion that vitamin D levels are low It is highly correlated with the risk of scarring. There are many treatment methods for keloid scars, which are also widely used in clinical practice, but people are still pursuing more convenient and feasible treatments for pathological scars. If many scientific research institutions can obtain similar research conclusions, vitamin D may become another “magic medicine” for the treatment of keloids or hyperplastic scars.

“Youpi” provoke someone, why keloids always pester me

Oily skin (oily skin) is born with “acne-causing” physique. Years and months of fighting against acne have caused large and small acne scars on the face and body, and even more difficult keloids. Why does oily skin cause keloid scars? How to prevent it? Today, I will explain it for everyone. Why does oily skin easily lead to keloid scars? For oily skin, the secretion function of sebaceous glands is relatively strong, leading to a large amount of sebaceous glands. The more vigorous the sebaceous glands, the more severe the stimulation of the sebaceous ducts, which will cause the ducts to be blocked. After the sebaceous glands cannot be secreted, the bacteria invade and cause the infection of the hair follicle sebaceous glands. , The formation of acne. If the long-term repeated infection of acne does not control the local inflammatory immune response in time, it will lead to the continuous scar proliferation effect and eventually form keloids. Therefore, effective care for oily skin and active treatment of acne can effectively prevent keloids. How does oily skin prevent keloids? 1. Pay attention to personal hygiene, take a shower and wash your face frequently, and clean your pores as much as possible; &nbsp.2, change your eating habits, try to eat less spicy, greasy, and high-sugar things. If you are allergic to seafood, try not to eat seafood;&nbsp.3, exercise, activate the body, let sweat wash the pores, reduce pore clogging. If the pores are unblocked, the probability of forming acne will decrease; &nbsp.4. If acne occurs, the simplest and most effective method for milder acne is to use iodophor for local disinfection, 2-3 times a day. 5. If the acne has “white heads”, it is necessary to promptly disinfect with iodophor and gently squeeze the pus out of the acne. Repeat disinfection more than 2 times a day. Use anti-inflammatory ointment as appropriate. 6. For pustular acne, a combination of local treatment and medication is needed to eliminate inflammation as soon as possible. In short, as far as possible to reduce the occurrence of acne infection, shorten the healing time of infected skin, the incidence of keloids will be significantly reduced, so as to reduce the formation of keloids. Treatment case sharing For keloids caused by acne, comprehensive treatment is carried out according to the principle of “differentiation and treatment” and in accordance with the 2018 Recommended Guidelines for Treatment of Keloids. Mr. Zhou, when he was adolescent, he had many acne on his face, especially the most serious part of the mandible, almost in one piece. In addition, he often squeezed the acne and induced infection, which caused many keloids to grow on the mandible. The appearance is accompanied by uncomfortable symptoms such as tingling and itching. When I came to the hospital for treatment, I combined Mr. Zhou’s situation to formulate a comprehensive treatment plan for him with drug injection and SRT-100 shallow radiotherapy. After systematic treatment, Mr. Zhou’s recovery effect is extremely obvious. From the comparison photos he sent back, it can be clearly seen that the almost continuous keloids have basically disappeared, and the skin color has basically returned to normal, achieving the purpose of treatment. . Oily skin is natural, but this does not mean that you will have keloids. As long as you actively clean your skin and treat skin diseases such as acne and folliculitis, you can effectively prevent keloids. Even if keloids grow, as long as they can be detected and treated as early as possible, they can get a better result.

Why are keloids susceptible to infection and rupture in summer? You have to do this to prevent infection

Not long ago, a patient consulted on the Internet, “My chest keloids have been around for 15 years. Recently, I have a little ulceration and discharge. It is very painful. I don’t know what to do?” Summer is the season when keloid patients are very uncomfortable. In the weather, keloids become more painful, itchy, hyperplasia, inflammation, and infection become more and more serious. Why are keloids prone to inflammation and infection in summer? How to care? Why are keloids easy to rupture? In a high temperature environment, sweat glands and sebaceous glands secrete relatively vigorously. These secretions are carried and wrapped inside the scar and cannot be discharged in time, causing sebaceous cysts or folliculitis, aggravating itching and pain, and even breakage and erosion after repeated scratching, forming scar infection ulcers . Picture source network, how to care for keloids in summer? 1. Pay attention to hygiene and prevent infection. In summer, the keloid area must be clean and hygienic. Partial areas should be cleaned frequently with water. Use a cotton swab or a small soft brush to clean the crevices of the scars every time you clean, so that no dirt remains in the crevices. 2. Dress appropriately to relieve itching. Due to the high temperature in summer, local sweat immersion and high temperature, the expansion of blood vessels in the local skin of keloids tends to aggravate the itchiness of keloids. Therefore, we should avoid dampness and high temperature environment in our life, and the clothes should have good air permeability and sweat absorption, so that the keloids should always be in a fresh and warm environment. When high temperature causes local pain and itching symptoms aggravate, appropriate cold compresses can relieve it to a certain extent. 3. Avoid irritation to prevent the scars from getting bigger. When the weather is hot, the clothes are thinner and the protection against injury is poor. The keloids often protrude on the surface of the body and are more likely to be injured. Once the scar is damaged, it is easy to stimulate the keloid and become more serious. Therefore, prevention of traumatic injury is also an important part of keloid care. In addition, pay attention to light diet and avoid spicy foods; pay attention to clean environment in daily life to avoid mosquito bites; I also need to mention that now is the dog days, many keloids are caused by folliculitis infection, so pay attention to folliculitis daily Or acne treatment to avoid secondary keloids. &nbsp. Care for ulcerated keloids is not enough. If they are not actively treated, they will generally prolong and recur, and long-term repeated infections may cause malignant changes. Therefore, it is recommended that patients with keloids must be treated as soon as possible to avoid repeated infections.

Boys, get rid of scars early!

This morning I saw a patient with keloids. The patient was a college student or a member of the school football team. At first, some keloids were caused by acne, but it was not too serious, but it was two. Years later, the longer the pimples on the body, the more they grow, and the scarring pimples are stimulated by sweating after each exercise, and the itch is very unbearable. This is why I came to the hospital for treatment during the summer. I pointed out after the inspection that if keloids were first noticed when they first appeared, early treatment would not only have a better effect, but also get a better appearance. It is precisely because many people, especially young people, do not pay attention to the lack of understanding of keloids, which delays the best time and increases the difficulty of treatment. Today, I will share with you some knowledge of keloids. What is keloid? Keloids are benign tumors of fibrous tissue on the skin. They generally appear as a continuous growth mass that is higher than the surrounding normal skin and beyond the original injury site. It is harder, less elastic, and itchy or painful. Exceeding the injury boundary is the biggest feature that distinguishes it from other scars. It is more common in young adults under the age of 30, and is more likely to appear on the upper neck, ears, chest, shoulders and upper arms. &nbsp. A very important factor inducing keloids is acne or folliculitis. For example, this patient who was treated today belongs to this situation. Because the sebaceous glands secrete vigorously in young people, the ducts of the sebaceous glands are blocked, and the sebaceous glands cannot be ruled out. It takes a long time for bacteria to invade and cause infection of the sebaceous glands. &nbsp. If the long-term repeated acne infection does not control the local inflammatory immune response in time, resulting in a continuous scar hyperplasia effect, keloids will eventually form. Scars you can’t ignore? 1. Affect the external appearance&nbsp. Scars are raised on the skin surface, and the color is red or dark red. If it grows in the easily exposed parts such as the lower jaw, the front chest or the back, it is easy to cause others to have a different vision and cause people to produce. Inferiority complex. &nbsp. 2. Growing and infiltrating the surrounding normal skin keloids has a tendency to grow continuously. If left untreated or incorrectly treated, the scars will gradually erode the surrounding skin, causing the scars to grow into pieces, the more the lesions range Come bigger. &nbsp. 3. Pain and itching symptoms of irregular attacks At present, there is no good relief for the pain and itching symptoms of keloid attacks. This kind of pain and itching is quite tormenting, and the attacks are not regular, the weather is sweating, Rubbing of clothing or irritating food may cause itching of the scars, and keloids cannot be scratched when itching, otherwise it will stimulate the keloids as they grow longer. Multi-therapy combined treatment of keloids keloids not only have the above-mentioned hazards, but also a refractory disease that is extremely difficult to treat clinically. It has the characteristics of treatment resistance and high-recurrence tumor diseases after treatment. Therefore, according to the “Guidelines for the treatment of keloids” formulated by the Scar Medicine Branch of the China Plastic Surgery Association in 2018, it is proposed that the treatment of keloids should be treated by a variety of methods, that is, comprehensive use of surgery, drug injection, laser, radiotherapy and chemotherapy, etc. Repairing means to remove scars and scars, to achieve smooth, smooth skin, close to normal skin color, and reduce recurrence. It is now in the summer, and the temperature is high in summer, the blood runs fast, the skin metabolism is strong, and the fibers and cells are in a more active stage. At this time, repairing scars is conducive to deep skin repair and tissue regeneration and reconstruction, which can quickly recover , Can play a multiplier effect. If you are suffering from keloids, do not ignore them. You should go to a regular medical institution for treatment as soon as possible to prevent keloids from getting bigger and bigger and harming your health.

When picking pox is cool, will it still be cool?

For many people, they have experienced the fierce anti-acne war, especially the battlefield with the face and neck as the main battlefield is the most fierce. No matter who wins, the two sides will be left with craters (acne marks) ). What’s more, because of repeated competition (infection) with acne in the local battlefield (jaw), it will also cause serious consequences-keloids. So, what method is used to treat keloids on the lower jaw? Today, I will introduce you to non-surgical combined treatment methods. Mr. Yang, during his adolescence, his face did not experience the brutal war against “acne”, but two years ago, his jaw grew a few acne. Because I didn’t take acne too seriously, I squeezed it away. I didn’t expect this squeeze to cause trouble for me. After the acne was squeezed, repeated infections occurred, which eventually led to a keloid on the left jaw. At first, the area of ​​keloids was not large, but the longer the six months later, the more it affected the appearance, and it was red, swollen and itchy, especially the itching was really unbearable. At one time, Mr. Yang was really itchy and also cut the keloids. This in turn stimulates the scars to grow up a lot. In order to get rid of scars, Mr. Yang was looking for treatments on the Internet. Once, he accidentally saw my live broadcast on a medical beauty app, which was a scientific lecture and case analysis on keloids. The easy-to-understand knowledge explanation and treatment case analysis made Mr. Yang see the hope of curing keloids. So, soon afterwards, Mr. Yang came to my clinic. After examining his mandibular keloids, I found that the scars were red, swollen, congested, and accompanied by itching and tingling, indicating that the keloids are currently in the inflammatory period, and good blood supply provides sufficient nutrition for the proliferation of scar tissue. Therefore, treatment measures must be taken as soon as possible to inhibit the continued growth of keloids, so as not to erode the surrounding normal skin. In response to Mr. Yang’s situation, I formulated a non-surgical combined treatment plan for drug injection plus SRT-100 shallow release. By blocking the blood flow of keloid tissue, cutting off its internal nutrition supply, preventing the keloids from continuously proliferating, and finally achieving the purpose of removing keloids and preventing recurrence. After the first injection treatment, the effect has begun to appear, and the redness and swelling have turned to dark red, indicating that the blood flow inside the scar tissue has been blocked. &nbsp. After the second treatment, the keloids appeared to be flattened and dull in appearance, and the effect was further shown. &nbsp. Because of the impact of the epidemic, Mr. Yang had another treatment in April today. At this time, the keloids have basically flattened and the color is close to normal skin. After systemic treatment, Mr. Yang’s keloids on his jaw have completely flattened out. From the latest feedback photos, the recovery effect is ideal, and no recurrence has been seen. I hope that there will be better results in the future. Finally, I remind the majority of patients with keloids that the chin is a frequent site of keloids, often caused by the failure of anti-acne. Once keloids appear, they need to be treated in time to prevent their continuous proliferation and erosion of normal skin, increasing the difficulty of treatment and affecting the prognostic effect. &nbsp.

Which parts of the head and face are more prone to keloids?

Compared with other parts of the body, scars on the head and face seem to be more unbearable. As an exposed part, changes in the head and face are more likely to be discovered, and they are more likely to cause adverse effects on normal working life and even physical and mental health. In order to better guide the prevention and treatment of keloids on the head and face, some scholars searched for a total of 1445 keloids results on major literature websites since January 2020, and analyzed relevant data. . After data analysis, it was concluded that the susceptible areas formed by keloids on the head and neck include the auricle, the area around the ear or the ear, the facial beard area, the jaw and the subchin area, and the lateral/rear scalp, while the central area of ​​the face is formed Keloids are less likely, and if they do, they are more likely to form hyperplastic scars. In addition to the characteristics of the site’s tendency, the literature also believes that long-term chronic inflammation (such as infection, foreign body reaction, and recurrent trauma) in postoperative wounds will increase the risk of excessive scars and keloid formation. The conclusions drawn from the analysis of clinical specific data are useful for the treatment of keloids, and these data have certain guiding significance for doctors to assess the risk of scar formation after surgery before performing surgery. With the development and accumulation of technology and experience, the treatment of keloids has become more mature, and the judgment of the best treatment plan for different keloids has become more accurate. Through the joint efforts of scientific researchers and clinicians, more and more keloid patients The treatment has regained confidence, which is good news.

Scars are not cured! relapse! Come see how many detours you have taken

Today, a patient with keloids consulted me: “Dr. Su, I got a three-year injection and relapsed in half a year. And the longer it gets, the more I tried it with ointment and laser, and it was really effective. Keloids are painfully tortured, is there any way to treat them?” Many patients suffer from keloids. To cure it, many methods have been tried, but the effect is not good, and many patients relapse after treatment. Happening. So, can keloids be cured? Why does it happen repeatedly? In fact, keloids can be cured. The reason for the poor effect and recurrence is because you have taken a detour when choosing a treatment. Why do some people think that keloids are not cured well? Keloids are essentially benign skin tumors, which generally appear as a continuous growth mass that is higher than the surrounding normal skin and beyond the original injury site. It is harder, has less elasticity, local itching or pain, and it is different from the wound boundary. The biggest feature of other scars. Many patients because of lack of understanding of keloids, mistakenly treat them as ordinary scars, and even go to the hospital in a hurry, blind treatment, such as going to the pharmacy to buy drugs at random or choose some unsafe prescription treatment. Because the internal tissue cells of keloids are more sensitive, if stimulated by external substances, not only do not remove the scar tissues, but also stimulate the proliferation of scar fibroblasts, resulting in the growth of keloids. In addition, dermatologists in many hospitals lack comprehensive knowledge of keloids or remain stuck in the traditional treatment concepts of the past. Therefore, in the treatment, it is still simply to adopt a certain treatment method, such as drug injection, surgery, laser, etc. This leads to recurrence of keloids after treatment. Without detours, comprehensive treatment is needed to get rid of scars! For some of the above reasons, some patients have lost confidence in the treatment of keloids. In fact, with the continuous development and advancement of medical technology, the treatment of keloids has been continuously promoted, and the treatment concept has also undergone a great change. According to the “Guidelines for the Clinical Treatment of Keloids” developed by the Scar Medicine Branch of the China Society of Plastic Surgery and Beauty in 2018, for keloids, drug injection, laser, surgery, freezing, radiotherapy, etc. should be taken according to factors such as location, age, area, and cause of disease. Chemotherapy and other comprehensive treatments can achieve a better treatment effect, and at the same time can greatly reduce the recurrence rate of keloids. Case analysis: Ms. Bai, due to folliculitis, two large keloids grow on the front chest, accompanied by severe itching symptoms. During treatment in our hospital, I recommend surgical resection, but the patient is somewhat resistant to surgical treatment. Therefore, according to the patient’s desire to “control the keloid pain and itch first, and prevent it from growing longer”, I developed a comprehensive plan for her with drug injection combined with SRT-100 shallow radiotherapy. After many treatments, Ms. Bai’s front chest scars have been effectively controlled. Not only have they become smoother, but the symptoms of itching have also disappeared. However, Ms. Bai feels that her appearance is not ideal and hopes to improve the appearance of scars. According to the patient’s situation, I decided to take a comprehensive plan of surgical resection plus SRT-100 superficial radiotherapy. The relatively large area of ​​keloids was surgically removed, and after a period of recovery, the overall appearance was very good, basically meeting the patient’s treatment requirements, and no recurrence after repeated visits. Finally, I emphasize once again that the treatment of keloids has a very high recurrence rate in the past, and the so-called remedies and secret recipes are more likely to cause aggravation of the disease. The longer the keloids, the greater. Therefore, scar friends should choose to go to a regular medical institution and take a variety of comprehensive treatments in order to avoid detours and obtain better treatment results.

Application prospect of pirfenidone in treating keloids

The treatment of keloids is constantly updated and developed. At the same time, the research on the treatment of keloids is also constantly being carried out. Not long ago, some scholars published a related literature about pirfenidone inhibiting keloids. &nbsp. Keloids are benign proliferative skin lesions that are difficult to treat and are a source of distress for patients. As far as its mechanism is concerned, recent literature shows that the conversion of keloid epidermis to dermis is one of its important pathogenesis. In the past, by studying the effect of the antifibrotic drug pirfenidone on keloid keratinocytes, it was found that pirfenidone has a certain inhibitory effect on keloids. In the experiment, keratinocytes isolated from normal skin tissue and scar tissue were cultured in vitro, and the effects of pirfenidone on cytotoxicity, cell migration, cell proliferation, and EMT-related genes and protein expression were studied. The experiment found that pirfenidone can significantly reduce the levels of vimentin and fibronectin in normal and keloid keratinocytes, and hinder the migration of basal cells. When the concentration of pirfenidone was from 200-1000ug/ml, the proliferation rate of cell basal cells showed a significant dose-dependent decrease. When the concentration of pirfenidone was as high as 1000ug/ml, the experiment did not find any cytotoxic effect . This study suggests that pirfenidone may inhibit the progress and recurrence of keloids. The literature shows that pirfenidone may have the prospect of treating keloids, but it is worth noting that the response of the same cells to the same drugs in vivo and in vitro is usually different. The most important thing is the effect of pirfenidone on cells in the body. The experimental results still need to be supported by clinical application data.

Both parents and siblings have keloids. Is it a genetic disease?

In the treatment of keloids, many of the immediate family members of patients also developed keloids. Therefore, some patients worry that keloids are a genetic disease, and even more so they will be passed on to the next generation. So, are keloids a genetic disease? Today, we will give you a relevant explanation through a real case. Ms. Xin, a few years ago, because of the infection of the pierced ear wound, the ear lobe of both ears developed keloids. Two surgical operations were performed in the local hospital, but there were recurrences. The longer the keloids grow, the more eroded the entire ear lobe. These two huge lumps are very detrimental to the appearance, even when using hair, it is difficult to hide. Originally depressed because of keloids, I did not expect to have an accidental leg injury since then, and there were keloids on the two injured parts of the left leg, which is really not a single disaster. In order to treat keloids, Ms. Xin also tried other treatment methods, but no matter whether injections or medicines, or lasers, freezing, etc., they did not have very good results. Repeated treatment failures have made Ms. Xin almost lose hope. Fortunately, in the process of seeking medical treatment, she met a lot of patients with keloids. Everyone encouraged each other and shared the treatment experience, so that Ms. Xin did not completely lose confidence. Peak circulation, hope for treatment to reappear. A patient with keloids whom Ms. Xin met in early May this year shared her treatment process and postoperative recovery effect in our hospital. This patient is a scar on the chest. Under my treatment, the appearance of the wound recovered well after the operation. Seeing such a good recovery effect after surgery made Ms. Xin see hope again. So soon, accompanied by his family, he came to our hospital for a consultation. After some consultations, I not only had a comprehensive understanding of Ms. Xin’s condition, but also learned that Ms. Xin’s brother and her father also had keloids on them. This shows that Ms. Xin’s family has a family genetic tendency. Ms. Xin was very worried about this and asked if keloids would be passed on to the next generation? I explained: “Keloids are not a genetic disease, but they do have a certain genetic predisposition. At present, the pattern of keloid inheritance is still inconclusive. Most experts believe that the genetic pattern is autosomal dominant. That is to say , One of the parents has keloids, then the chance of the child getting sick is higher than those without family history. Of course it is not 100% long, but the probability is greater. Even if the loved ones have keloids, we don’t have to be afraid. We It is possible to reduce the probability of keloids by preventing and correcting skin damage.” After listening to my explanation, Ms. Xin was relieved. Subsequently, I formulated a comprehensive treatment plan for surgical resection plus SRT-100 superficial radiotherapy for Ms. Xin’s keloids. After the operation, Ms. Xin’s ear lobe and keloids on her leg were successfully removed, and she received effective wound reduction treatment. Ms. Xin was very satisfied with the treatment and said that she would also let her family come to the professor for treatment and get rid of the scars of keloids as soon as possible. Finally, I would like to remind the majority of scares that clinical statistics show that patients with keloids with a genetic predisposition have a higher recurrence rate than patients without genetic characteristics. This requires active treatment measures to prevent relapse after treatment. In addition, we must pay attention to avoid injury in daily life, if there is folliculitis, acne, do not squeeze, so as not to cause infection and induce new keloids.

Are keloids indistinguishable from hypertrophic scars? In fact, only one trick can tell

Both keloids and hypertrophic scars are pathological scars. Medical research has shown that these two diseases are different in terms of pathology, symptoms, predisposed sites, and growth trends. However, there are many similarities between the two clinically. If the diagnosis is deviated and incorrect treatment is taken, it will have an adverse effect on the treatment. So, how to distinguish between keloids and hypertrophic scars? Today, I will explain this issue through a case. Ms. Xiao, on her way to school many years ago, she accidentally collided and accidentally injured her right elbow joint. In addition, poor postoperative wound care caused infection and poor healing, and eventually left a large raised scar on the elbow joint. Over the years, this scar has been bothering her, especially in the summer when she dared not wear short-sleeved dresses. Sometimes the weather changed suddenly or she ate some spicy food. There were obvious symptoms such as tingling and itching. &nbsp. Ms. Xiao also went to the hospital for treatment. At that time, she was diagnosed with hypertrophic scars. She had received injections and lasers, but the results were not satisfactory. Since then, I have tried external application of ointment, massage, eating Chinese medicine, etc., the money is not spent, but it is still useless. After many failed treatments, Ms. Xiao almost gave up her hope of healing until she once saw a video explaining scar repair on Weibo, which gave her another glimmer of light. A few days later, she came to our hospital for treatment. After understanding Ms. Xiao’s situation, I carefully inspected the raised scar of her right arm elbow joint. From the outside, this raised scar is similar to keloids and hypertrophic scars, but with many years of clinical scar diagnosis and treatment experience, It is judged as keloid, but the possibility of hypertrophic scars cannot be completely ruled out. &nbsp. For the sake of safety, after I developed a comprehensive treatment plan for surgical removal and SRT-100 shallow placement for Ms. Xiao, I decided to perform further pathological examination on the scar tissue after surgery. After the operation, the raised scar that had troubled Ms. Xiao for many years was finally completely removed. The pathological examination of the cut scar tissue proved my original judgment that this raised scar was just a keloid. Finally, the distinction between hypertrophic scars and keloids is obvious in the medical definition, but in some clinical situations, the two are easily confused. In order to prevent misdiagnosis, this requires the doctor not only to have a solid medical knowledge base, but also to help the doctor make a correct diagnosis through some examination methods such as pathological examination. Only in this way can targeted treatment measures be taken to obtain a better scar removal effect.

What are the medical treatments for keloids?

There are many treatments for keloids, drug treatment is a common one, and for different patients with keloids, the most suitable drugs are also different. At present, the commonly used drugs for scar treatment can be divided into five categories: First, adrenal cortex hormones, the principle of action is to inhibit collagen synthesis, at the same time induce collagen degradation, inhibit fibroblast proliferation, damage scar endothelial cells, reduce blood supply, etc., making Scars become thinner and softer, commonly used drugs are triamcinolone acetonide, depot pine, etc.; 2. Chemical preparations can be divided into anti-tumor drugs (such as 5-FU), calcium channel blockers (such as verapamil) , Anti-allergic drugs (such as Tranilast, Diphenhydramine, etc.), tretinoin drugs, immune preparations, etc.; 3. Biological products, IFN, hyaluronidase, collagenase, botulinum toxin, etc.; 4. Chinese medicine Class, Salvia miltiorrhiza, Asiaticoside, Matrine, etc.; 5. Compound preparations, such as allantoin, etc. At present, drugs are often used in the form of scar needles for the treatment of keloids. The commonly used drugs for scar needle injections are the corticosteroid hormone triamcinolone acetonide. If keloid hyperplasia is severe, some anti-tumor drugs are usually added appropriately. Can get better results. Scar needle injection is used to treat keloids, usually 3-4 times as a course of treatment. In general, the injection can be suspended after the scar becomes flat and soft. Afterwards, it is necessary to closely observe the proliferation trend of the lesion. Once there are recurring signs, injection is required immediately. The treatment of keloids is a long-term battle. In addition to solving the existing problems, treatment also needs to prevent the recurrence of keloids, so doctors and patients should cooperate with each other to achieve better results.

The ears are occupied by three keloids, and the comprehensive treatment of surgery “rescue” the ears to restore their appearance

We know that the ear is one of the most prone areas of keloids, and it is mostly caused by piercing (ear piercing). Keloids affect the appearance of the ears. Many patients naturally want to get rid of them quickly, but they underestimate the high recurrence of this skin tumor. The result is that the cut is long and long, and the cut is longer. So, what method can effectively get rid of ear scars? After reading this case, I believe you can get the answers you want. For the beautiful and shiny earrings, the female friends who believe in beauty can’t resist its temptation. Ms. Ye is also one of them. Many years ago, she had made three pierced holes in the left and right ears, and began to wear earrings and earrings after finishing. However, the three ear holes in Ms. Ye’s right ear caused inflammation due to allergy to wearing earrings. Later, the inflammation subsided and three small pimples grew. At first, because the pimple was small and there was no discomfort, Ms. Ye didn’t care too much, thinking that it was just a few “bumps” that would disappear in a few days. But two years later, not only did the small pimples disappear, but they grew longer. When I went to the hospital for examination, I realized that the ears had keloids, a benign skin fiber tumor. In order to restore the ear appearance as soon as possible, Ms. Ye underwent excision surgery in the hospital. She thought it would be fine after the operation, so she underestimated the high recurrence rate of the disease. More than a year later, keloids came back, and the growth rate was very fast, and it was accompanied by severe itching, especially when the weather was abnormal, or after eating spicy and stimulating food, itching was unbearable, leading to insomnia throughout the night. There is no way but to go to the hospital for surgery again. After this resection, in order to prevent recurrence, Ms. Ye paid great attention to wound care, not only avoiding spicy food, but also applying anti-scarring drugs. But everything she did was in vain. It was still about a year later. The keloids recurred. It happened that Ms. Ye was pregnant at this time and it was not suitable for further treatment. During pregnancy, because of the drastic changes in hormone levels in the body, the keloids are stimulated to increase rapidly, and eventually grow into three huge pimples with hard texture and uneven surface, which almost completely cover the ears. Whenever I looked in the mirror and saw three huge ugly pimples on my ears, Ms. Ye was very depressed. Even the baby’s birth did not make her feel much better. In order to completely remove the scars on her ears, Ms. Ye consulted treatment plans around. I accidentally saw a case about my treatment of ear keloids on Weibo, which made her see hope again. So, soon came to our hospital for help. After understanding the situation of Ms. Ye, I pointed out that keloids are a benign skin tumor, and a single treatment method will have a very high recurrence rate. According to the latest keloid treatment developed by the Scar Medicine Branch of the Chinese Society of Aesthetic Plastic Surgery in 2018 Recommended guidelines for the treatment of keloids should be combined with multiple methods. In view of the huge area of ​​Ms. Ye’s ear scars, I developed a comprehensive treatment plan for her with surgical resection plus SRT-100 shallow placement. Surgical removal of keloids and repair of the appearance of the ear, while superficially inhibiting the excessive proliferation of wound fibroblasts and inhibiting the recurrence of keloids. After surgical treatment, the ears, which had been occupied by three keloids for many years, finally regained “freedom”, the appearance of the ears was preserved, and there was no recurrence after repeated visits after the operation. The overall treatment effect was satisfactory. Finally, I would like to remind the majority of patients with keloids that the treatment of keloids to restore their appearance is only the first step, and the corresponding anti-relapse treatment is also required in order to obtain satisfactory treatment results.

Can cryotherapy be used for keloids?

At the beginning of February, Cryobiology & nbsp. Published a document that mainly studied the effect of cryotherapy on keloids in the UK. Through retrospective analysis of clinical cases. The effects of cryotherapy on keloids in various parts caused by various reasons are summarized. The authors of the literature believe that cryotherapy is worthy of application. The literature summarizes the cryotherapy program: the average freezing time of each keloid is 21 minutes (3-60 minutes), the average scar volume is reduced by 83%, and the average time to complete healing is 45 days (21-135 days), 11% There are complications in the cases, which include: hair follicle loss, hypopigmentation, recurrence, bleeding, pain, and continuous exudation, of which the hypopigmentation recovers within one year. Regarding cryotherapy, in fact, there are also applications in China, and the scope is very wide, including: hemangiomas, lymphangiomas, moles, warts, corns, calluses, benign and malignant skin tumors, and some scholars believe that keloids are also benign skin tumors. It has been used in the past, but there are population differences between Caucasians and yellows. The efficacy of the same therapy is quite different. With the continuous development and maturity of treatment technologies, there are already better treatments and prevention of keloids. Method, so cryotherapy is not very common.

Be sure to check it out, are you a scar physique?

Anyone with scar physique can have infinite hyperplasia like keloid scars after any part of the body is injured, but keloids can appear in certain parts of the normal population, or the scars healed due to certain reasons. In other words, keloids are an inevitable manifestation of scar physique, and those who have keloids do not necessarily belong to people with scar physique. This kind of person after the wound healed. The surface scars continue to increase, which not only affects the appearance, but also local pain, red itching, and scar contraction also affects functional movement. Generally, patients with hypertrophic scars and keloids can be judged as scar physiques; in layman’s terms, the scars protrude from the skin surface and are larger than the wound area after trauma. People with scar constitution are prone to form hyperplastic scars or keloids with obvious symptoms after surgery, burns, and trauma. At present, in medical science, the scar constitution can only be diagnosed according to the performance of the individual, but it is impossible to truly test whether a person is a scar constitution by which test index. In fact, very few people have real scars. Diagnosis of scar physique is subject to judgment, and treatment is also very cautious, and sometimes the loss is greater than the gain after treatment.

How to tell if it is keloid? What are the hazards?

Keloids are not the same as the scars we usually see. Keloid is actually a disease, also called keloid. Because keloids are raised, the biggest difference from ordinary hyperplastic scars is that it will exceed the injured area and grow infiltrating into the surrounding area, which is its biggest feature. 1. Are scars and keloids the same thing? It’s totally two different things. First, keloids will exceed the injured area and grow infiltrating into the surrounding area, losing normal skin around. Second, it doesn’t need to have too much injury, even if the mosquito bites, nails scratched, Heavier keloids may grow. 2. Keloids are also caused by wounds? There are also some people who have no obvious history of trauma and have developed keloids. Keloids do not require too serious injuries, and even an acne will grow into keloids, which is related to its own constitution and is a problem with the function of the body. For example, normal scars stop growing after the acute hyperplasia period, because the body has a brake for repair, and when the damaged skin is connected, it stops repairing. However, the brake function of the keloid patient has failed. His body has been repaired and has been growing scars, and not only grows in situ, but also spreads around. This is caused by a skin dysfunction. 3. How to diagnose it as keloid? First, keloid injuries are very light, some people have acne, and some people may be bitten by a mosquito, very light or no history of trauma. Second, the biggest feature of keloids is that it will exceed the original injured area and grow invasively to the surrounding area. This process lasts for a long time, and it can’t even stop. 4. For keloids, if treatment is not taken in time, it only affects the appearance, will it affect our health? For keloids, it will grow infiltrating into the surrounding area and lose the normal skin around it. And when the keloids are particularly long, it will itch and hurt, and some people will sleep hard at night, which will affect the quality of life. If the keloids are particularly large in the later period and become involved in a lot of normal skin, an infection will occur. This ulcer infection is red and swollen, and often runs out of the soup, resulting in poor quality of life. It is recommended to treat it in time. 5. For those who have keloids, he may worry, will it be passed on to his next generation? For keloid patients, only a few have a family genetic history, most of them are sporadic, and may not be passed on to the next generation.

Are you a hyperplastic scar?

Hypertrophic scars are more common in trauma that is only deeper than the dermis. The difference between the pathological tissue of hypertrophic scars and normal scars is only the thickening of collagen fibers in the deep part of the scars, which is irregularly arranged, or in a wave shape, or entangled into a rope. Hypertrophic scars mostly occur after deep burn wounds heal. Reticulated proliferative scars are also common at the sutures around the skin graft after skin grafting in third-degree burn wounds. In addition, the most common is that any incision scar after suture also belongs to this type. Hypertrophic scars are characterized by protruding surface, irregular shape, unevenness, flushing and hyperemia, solid and tough. Feeling of burning and itching. The characteristics of hypertrophic scars are: early local swelling, hardening and congestion, its tissue structure is covered by a layer of atrophic epithelial cells on the surface, the middle layer is dilated by blood vessels, and is infiltrated by inflammatory cells, the bottom layer is less collagen fibers and a lot Of connective tissue hyperplasia. This kind of scar is higher than the surface of the skin, thickened and hardened in the early stage, and the capillaries are red or dark red. The base of the scar is generally not adhered to deep tissue, can be pushed, and has less contractility. Most of them will not cause serious dysfunction, but it often affects beauty on the face and exposed parts, so it is often necessary for treatment. The shape and size of hypertrophic keloids vary according to the condition of the injury: the surgical incision is often strip-shaped. Scratching, which can be caused by injection, can be cord-shaped or small. The hypertrophic keloids are mostly horizontal strips on the front chest , There are often typical crab-footed branches, which are called butterfly spots. Those who occur after scald or burn, their size and thickness are closely related to the area and depth of the injury. The deeper the injury, the thicker the hypertrophic keloid. Large area damage It can cause motor dysfunction due to scar contracture. Occurrence at the joint site can cause limb contracture, limited movement, and even affect normal work and life. Hyperplastic keloids occur on the face and can be disfigured. Patients with hypertrophic keloids manifest as an obvious family Hereditary. Hyperplastic keloids have significant body parts, strong sternum, shoulder deltoid, mandible, auricle, etc. As the disease progresses, hypertrophic keloids go beyond the original damage range and gradually infiltrate the surrounding normal skin . Therefore, the scar is always an imperfect replacement for the damaged tissue. From a mechanical point of view, its resistance is weakened. From a nutritional point of view, it causes obstacles to the exchange of oxygen and nutrients. From a functional point of view, it causes deformities and dysfunction of damaged tissues. From an aesthetic point of view, it creates a shape Of destruction.

The hotter the weather, the faster the keloids grow? The treatments you want to know are here!

Recently, the weather is getting better and better. Some time ago, my friend and I went shopping together and bought a lot of summer clothes. But when I tried on clothes, I found that my friend only took some long-sleeved trousers and never tried those beautiful little skirts. I only knew when I asked her that she was scornful of the scars on her body and was afraid to show her skirts. Summer is coming, but there are many little cutes like my friends, because of the scars on their bodies, they dare not show their skin. However, covering does not stop the growth of keloids. In the hot weather season, the growth rate of keloids is also accelerating. There are 4 stages in the process of keloid growth, and the symptoms of different stages are also different. Do you know which stage your keloids are in? & nbsp.NO1. The four major periods of keloid growth1, the initial stage & nbsp. The surface of the skin appears red dots of rice grain size and some itch, but don’t scratch it by hand. Most people mistakenly think that it is hair follicle inflammation and vascular nevus. When the condition gradually develops, the skin lesions gradually increase, and the folliculitis subsides, and there is no obvious change in vascular nevus. This period is the initial performance of keloids and the easiest to repair. To sum up a word: treat scars, as early as possible and not late. & nbsp.2, early stage & nbsp. Early red scars are infiltrated around or have insignificant mild infiltration, varying in size, and sometimes no itching. This period is easy to be confused with hypertrophic scars. It is recommended to go to a professional regular hospital to carefully check whether the edges are infiltrated or extended, and make accurate judgments. & nbsp.3, Mid-term stage & nbsp. At this stage, keloids have formed into flakes from a single, red lumps on the surface of the skin, surrounded by bright red outward infiltration zone. The typical ones are butterfly-shaped or crab-like, with a duration of several years or ten years. 4. Late stage & nbsp. The late stage of keloids has a wide distribution, large area and a large number of scars. In the late stage, one or two scars may shrink and become darker in color from a blood red to a dark red in large areas of keloids, but the number of other lumps may still be in the middle, or it may be early or early scars. It can also be advanced in the central part of a large keloid, and the surrounding is still in the middle stage of active hyperplasia and infiltration to the surrounding. This is a common form of keloid development. The more difficult the treatment, the better it is to treat it anyway. In my Weibo collection, I always see someone asking: “Professor, keloids are always repeated. Why is this?” “How should I treat it?” I will focus on these two questions. & nbsp.NO2. Why do keloids repeat? Keloids are like ghosts that don’t disperse. After the treatment, not only did the smoke disappear, but the comeback and ferocity came back, making it more difficult to parry than before. First of all, keloids are prone to relapse because of its extremely strong “vitality”. & nbsp. Scars can swim and grow up. No matter in the hyperplasia or maturity period, the scar tissue will be constantly updated due to the environment-it is not just a mass of meat on the wound, but also a living, change-filled tissue. (It sounds a little scary!) SO, you need a hit to treat it. Wrong treatment can easily lead to recurrence of keloids. It can even stimulate scars and make the scars bigger. Secondly, there is no adherence to treatment. There is an extra piece of flesh on the body, and it looks very eye-catching and hopes to be “quick and quick”, but keloids are not grown up in a day or two. Keloids are most afraid of the cessation of treatment, the more relapses, the greater the relapse. This requires the attending doctor to customize a comprehensive repair plan for the patient, and the patient must also actively cooperate. NO3. The complete guide for keloids because keloids themselves are very unstable and a little irritating. Sometimes they induce more intense hyperplasia. Within the range of keloids. 1. & nbsp. & Nbsp. Partial closure of keloids is a very effective way. For example, the long-acting hormone depot pine, in which betamethasone dipropionate is slowly released, can continuously inhibit the growth of keloids within two to three weeks. Therefore, this method of closure is more suitable for fresh or proliferating keloids, or as an adjunct therapy during treatment. 2. On the increase

Scars on the chest due to acne, non-surgical comprehensive treatment to eliminate skin damage

Girls all want to have flawless whitening and delicate skin, but skin fibrous tumors such as keloids are unequivocal skin “destroyer”, and if not treated in time, they will become more and more rampant and continue to erode the surrounding normal skin tissue. Tingling, itching and other discomfort. Therefore, the “destroyer” of this skin should be eliminated as soon as possible. Ms. Xiao, her dress style has changed a lot in the past year. She likes to wear high-necked, semi-high-necked and round-neck clothes. Her friends and colleagues are very curious about her sudden change. In fact, Ms. Xiao is suffering. It turned out that Ms. Xiao had two acne on her chest, and it was a little itchy. At that time, she did not care too much and squeezed it. She did not expect a wound infection. Due to the hot weather, she was prone to sweat and the clothes and the wound rubbed, which caused repeated The ulcer infection, although the inflammation subsided, grew two keloids, one large and one small. These two keloids on the front chest have a great impact on Ms. Xiao’s life. In order to prevent others from seeing, she can only change her dress style. Not only does it affect the appearance of the skin, but keloids often appear uncomfortable symptoms such as itching and tingling, especially when itching is severe, it is really difficult to bear, so I want to use surgery to grab it. In order to deal with these two keloids, Ms. Xiao has also invested a lot of time and money to buy many scar removal products. All kinds of ointments, potions, pills have been tried, and the effect may not be obvious, or at first, some effects, gradually in the later period invalid. While Ms. Xiao was worried about treating keloids, she accidentally saw my case article on Weibo. The article content was about how to treat keloids on the front chest, and the pathogenesis of keloids was very explained. The professionalism and meticulousness invisibly gave me a sense of trust, and also made Ms. Xiao see the hope of cure. She soon came to our hospital for consultation. I pointed out after the examination that Ms. Xiao can clearly see the rich blood vessels under the epidermis of keloids with a large front chest area, indicating that she is currently in the inflammatory stage, and good blood supply provides sufficient nutrition for the proliferation of scar tissue. Therefore, treatment measures must be taken as soon as possible to inhibit the growth of keloids and erode the surrounding normal skin. In response to Ms. Xiao’s situation, I developed a non-surgical comprehensive treatment plan for her with drug injection plus SRT-100 shallow release. By blocking the blood flow of keloid tissue, cutting off its internal nutrition supply, preventing the keloids from continuously proliferating, and finally achieving the purpose of removing keloids and preventing recurrence. After the system standard treatment, the effect can be said to be very satisfactory. From the latest feedback photos sent by Ms. Xiao, the two keloids have become flat, and basically no traces can be seen. Although there is still some slight coloration, it will gradually fade over time and return to normal skin tone. By eliminating the “destroyer” of the skin entrenched in the front chest, Ms. Xiao can finally return to normal life without worrying about it.