Chongqing Vitiligo Hospital, which trace elements are related to the incidence of vitiligo? Trace elements play a very important role in the health of the body. Active substances involved in the intermediate links of the body’s metabolism, such as copper, zinc, selenium, etc., are directly involved in the synthesis of melanocytes and protect melanocytes from heavy metal poisons. . The relationship between vitiligo and copper element Chongqing Vitiligo Specialist Hospital introduces copper is an essential trace element for the human body, which can help the iron transfer protein, play an important role in the formation of heme, and in the food cooking process, copper element is not easy to be destroyed Copper is a coenzyme of tyrosinase, which plays an important role in the formation of skin pigment. Tips for supplementing copper for patients with vitiligo: 1. Although the unit of copper in the human body is very small, if too much copper is taken in, it will cause human body weight metal poisoning. If the onset of vitiligo is due to the lack of copper ions, it needs to be supplemented scientifically under the guidance of a doctor. 2. Whether patients with vitiligo need to add copper elements, they should observe whether their own copper ions are lacking and whether they need to be supplemented after completing the trace element test. Follow the doctor’s advice and do not add trace elements by themselves. Otherwise, not only is it ineffective against vitiligo, it may also cause other diseases of the body. 3. Vitiligo patients who lack copper ions can eat more copper-containing foods such as snails and mussels in their daily lives to supplement the lack of copper. Copper-containing food list: rich sources: mushrooms, burdock, hazelnuts, sunflower seeds, sesame paste, watermelon seeds, etc.; Chongqing Vitiligo Specialist Hospital introduces good sources: broad beans, fresh mushrooms, cumin, green beans, black sesame seeds, soybeans and their products, mung beans , Pine nuts, peanuts, potato flour, seaweed, tofu powder, lotus seeds, kidney beans, edamame, shiitake mushrooms, gluten, fruit peel, peas, chestnuts, oatmeal, nuts, etc.; general sources: peanuts, peanut butter, butter, bread, bananas, rice crackers , Mung bean cake, etc. Reminder: The cause of vitiligo is complicated. Not all patients are caused by the lack of copper ions. Therefore, patients should not blindly supplement the “copper” element. After checking the condition and cause of the disease, treat it according to the doctor’s advice.
Although the content of trace elements in the human body is small, it plays a very important role in the health of the body. They are active substances that directly participate in the intermediate links of the body’s metabolism, such as copper, zinc, selenium, etc., participate in the synthesis of melanocytes, and protect melanocytes from heavy metal poisons. Clinical studies have also proved that many patients with vitiligo have copper deficiency. Because the usual intake of trace elements is too small, resulting in a decline in the body’s immunity, vitiligo can be exploited. If the onset of vitiligo is due to lack of copper ions, it needs to be supplemented scientifically under the guidance of a doctor. Vitiligo patients’ copper supplement instructions: 1. Although the unit of copper in the human body is very small, if too much copper is taken in, it will cause human body weight metal poisoning. Under normal circumstances, the intake of copper is 0.4-1.0 mg/day in infants and 1.5-3.0 mg/day for adults, and the absorption rate is 30-40%. 2. Whether patients with vitiligo need to supplement copper elements, they should observe whether their own copper ions are lacking and whether they need to be supplemented after completing the trace element test. Follow the doctor’s advice and do not supplement the trace elements by themselves. Otherwise, it is not only ineffective against vitiligo, but may also cause other diseases of the body. 3. Vitiligo patients who lack copper ions can eat more copper-containing foods such as snails and mussels in their daily lives to supplement the lack of copper. Vitiligo has complicated causes, and not all patients are caused by copper ion deficiency. It has been clinically found that there are also some patients with internal copper ion metabolism disorders, which need to be checked for the condition and cause of the disease, and then repaired through effective drugs.
Clinical manifestations: is divided according to the type of clinical seizures: 1, systemic tonic-clonic seizure (major seizure): Sudden loss of consciousness, followed by ankylosing and clonic spasm. Often accompanied by screaming, bruising, urinary incontinence, tongue bite, white foam or blood foam in the mouth, and dilated pupils. After a few tens of seconds or a few minutes, the seizures naturally stop and enter a lethargic state. After waking up, there is a short period of dizziness, irritability, fatigue, and no recall of the seizure process. If the seizure continues, those who have been in a comatose state are said to have sustained a major seizure, which is often life-threatening. 2. Missing seizure (small seizure): Sudden interruption of mental activity, loss of consciousness, may be associated with myoclonus or automatism. A few seconds to more than ten seconds. The electroencephalogram appeared 3 times/second spiny slow or sharp slow wave synthesis. 3. Simple partial seizures: Part of one or one limb’s rigidity, clonic seizure, or paresthesia seizure, which lasts for a short time and clear consciousness. If the range of the attack extends to other limbs or the whole body along the movement area, it may be accompanied by loss of consciousness, which is called Jackson attack (Jack). The affected limb may have temporary paralysis after the attack, called Todd’s palsy. 4. Complex partial seizures (psychomotor seizures): psychosensory, psychomotor and mixed seizures. There are many degrees of consciousness disorder and obvious thinking, perception, emotion and psychomotor disorders. There may be manifestations of automatism such as wandering syndrome and nocturnal syndrome. Sometimes, under the control of hallucinations and delusions, violent behaviors such as wounding and self-injury can occur. 5. Autonomic seizures (diencephalon): can have headache type, abdominal pain type, limb pain type, syncope type or cardiovascular type attack. Those with no clear etiology are primary epilepsy, and those secondary to intracranial tumors, trauma, infections, parasitic diseases, cerebrovascular diseases, systemic metabolic diseases, etc. are secondary epilepsy epilepsy examinations: 1.EEG, BEAM, Holter (electroencephalogram, electroencephalogram, dynamic electroencephalogram monitoring): clear pathological waves, spike waves, sharp waves, spike-slow waves or spike-slow waves can be seen. 2. If it is secondary epilepsy, head CT, head MRI, MRA, DSA, etc. should be further examined to find the corresponding lesions. 3. Epilepsy and biochemistry: Epilepsy is closely related to various chemical substances in the human body. Neurobiochemistry is important at the molecular level to elucidate the pathogenesis of epilepsy. A. Biochemical changes in the brain during the seizure (1) The process of seizures It is often accompanied by abnormal changes in arterial oxygen partial pressure, arterial carbon dioxide partial pressure, blood glucose, non-lipidated fatty acids, ATP, chromium, phosphorus, glutamate, glutamine, lactate, GABA, etc. (2) Oxygen demand increases during seizures, glucose metabolism accelerates, brain creatine phosphate concentration decreases, and creatine concentration increases. (3) During the epileptic seizure, serotonin decreases, dopamine content decreases, and cholinesterase activity increases. B. Brain energy state and metabolic reserve at the time of the attack The brain’s glucose content decreased rapidly after the attack, and glycogen returned to normal two hours later. This is related to the increase in plasma insulin concentration during seizures. Within a few seconds of the onset of generalized seizures, the concentration of creatine increased while the concentration of phosphocreatine decreased. ATP concentration decreases when hypoxia, arterial hypotension or hypoglycemia occurs. C. Epilepsy and monoamine transmitters Monoamine transmitters include serotonin, dopamine, epinephrine, acetylcholine, etc. During the seizure, serotonin in the brain is reduced, dopamine content is reduced, and cholinesterase activity is increased. D. Epilepsy and amino acid transmitters Amino acid transmitters include GABA, Glu, ASP, Gly, Ala, Tau. Among them, GABA is the main inhibitory transmitter in the brain, and glutamic acid is the main excitatory transmitter in the brain. E. Epilepsy and cyclic nucleotides cyclic nucleotides include cyclophosphadenosine (CAMP) and cyclophosphoguanosine (CGMP), which are the “second messengers” of central nervous cells and play an important role in regulating central nervous system activity. F. Epilepsy and neuropeptides Neuropeptides are a class of compounds linked by dozens of low molecular weight single-chain amino acids. It is involved in the pathogenesis of epilepsy. G. Epilepsy and calcium ions and calmodulin calcium ions can regulate many cell biological processes through the activation of calmodulin; calmodulin is an important calcium binding protein of the human body, as a receptor for calcium action, is to assist Calcium ion is a medium for various physiological functions. Calcium ions and seizures