What organ diseases can rheumatism cause?

1. Rheumatic Pancarditis   Rheumatic disease often involves all layers of the heart, so it is called rheumatic pancarditis (rheumaticpancarditis).   1. Rheumatic endocarditis: Rheumatic endocarditis (rheumaticendocarditis) often violates the heart valve, of which the mitral valve is most often involved, followed by mitral valve and aortic valve at the same time. The tricuspid valve and the pulmonary valve are generally not involved. The tendon and the intima of the left atrium wall can sometimes be violated.  The early stage of the disease is serous endocarditis, and the valve is swollen and translucent, but this early change is almost invisible at autopsy. Under the microscope, the valve becomes loose due to serous exudate, accompanied by the infiltration of macrophages, and cellulose-like necrosis of collagen fibers. After that, Anitschkow cells appeared around the necrotic foci, and Aschoff bodies formed in severe cases. After a few weeks, there is a single row of verrucous growths with a diameter of 1 to 2 mm on the valve closure margin. This type of endocarditis is also known as verrucousendocarditis. These warts are gray-white translucent, firmly attached, and generally not easy to fall off. Under the microscope, the warts are white thrombus composed of platelets and cellulose. The warts mainly occur on the atrial surface of the mitral valve and the ventricular surface of the aortic valve. The reason is that the inflammation of the valve affects the endothelial cells and damages the endothelial cells. Frequently subjected to friction and blood flow impact, shedding damaged endothelial cells and exposing the collagen under the endothelium, leading to thrombosis. Sometimes, there is thrombosis in the left atrium wall. In the late stage of the lesion, fibrosis occurred in the subendocardial lesions, and organs of warts also developed. As rheumatism often recurs, scar formation is increasing. The intima of the heart wall can be thickened, roughened, and shrunken, especially the posterior wall of the left atrium, which is called McCallum’s patch. Due to repeated attacks and organization of the heart valve, a large amount of connective tissue hyperplasia causes thickening, curling, shortening, and calcification of the valve. Adhesion and fibrosis may occur between the leaflets, and the tendon thickens and shortens, resulting in chronic formation. Heart valve disease.   2. Rheumatic myocarditis: Rheumatic myocarditis (rheumatic myocarditis) mainly involves myocardial interstitial connective tissue. The connective tissue near the myocardium has fibrinoid necrosis and then forms Aschoff bodies. The corpuscles are diffusely or locally distributed, vary in size, and are mostly fusiform, most commonly in the posterior wall of the left ventricle, ventricular septum, left atrium, and left atrial appendage. Later, fibrosis occurred in the corpuscle, forming a fusiform scar.  Sometimes in children, the exudative lesions are particularly obvious, and the myocardial interstitium has obvious edema and diffuse inflammatory cell infiltration. Severe cases often cause cardiac insufficiency.  Rheumatoid myocarditis can often affect myocardial contractility, clinically manifested as a rapid heartbeat, the first heart is blunt, and severe cases can lead to cardiac insufficiency. The prolonged P-R interval is common on electrocardiogram, which may be caused by the lesion affecting the atrioventricular node or vagus nerve excitation.   3. Rheumatic pericarditis: In rheumatism, the pericardium is almost always involved, but clinically, only 15% of rheumatic pericarditis cases are diagnosed. The lesion mainly involves the pericardial visceral layer, which is serous or serous cellulose inflammation, and the epicardial connective tissue may undergo cellulose-like degeneration. There can be a large amount of serous effusion (pericardial effusion) in the pericardial cavity. The perimeter of the heart expands to the left and right. The heart sounds are distant during auscultation. X-ray examination shows that the heart is pear-shaped. When a large amount of fibrin oozes out, the cellulose on the surface of the epicardium becomes fluffy due to the heart’s continuous pulsation, called corvillosum. During the recovery period, the slurry is gradually absorbed, and most of the cellulose is also dissolved and absorbed, and a small part of it is organized, resulting in partial adhesion of the pericardium in the dirty and wall layers. Very few cases can completely heal, forming constrictive pericarditis ( consrictivepericarditis).  Second, rheumatoid arthritis  About 75% of patients with rheumatic fever have early rheumatic arthritis (rheumatic arthritis). Large joints are often involved, most commonly in the knee and ankle joints, followed by the shoulder

What organ diseases can rheumatism cause?

 I. Rheumatic Pancarditis  Rheumatoid lesions often involve all layers of the heart, so it is called rheumatic pancarditis (rheumatic pancarditis).   1. Rheumatic endocarditis & nbsp. Rheumatic endocarditis (rheumaticendocarditis) often violates the heart valve, of which the mitral valve is most frequently involved, followed by mitral valve and aortic valve at the same time. The tricuspid valve and the pulmonary valve are generally not involved. The tendon and the intima of the left atrium wall can sometimes be violated.  The early stage of the disease is serous endocarditis, and the valve is swollen and translucent, but this early change is almost invisible at autopsy. Under the microscope, the valve becomes loose due to serous exudate, accompanied by the infiltration of macrophages, and cellulose-like necrosis of collagen fibers. After that, Anitschkow cells appeared around the necrotic foci, and Aschoff bodies formed in severe cases. After a few weeks, there is a single row of verrucous growths (valrucousvegetation) with a diameter of 1 to 2 mm arranged on the margin of the valve. This type of endocarditis is also known as verrucousendocarditis. These warts are gray-white translucent, firmly attached, and generally not easy to fall off. Under the microscope, the warts are white thrombus composed of platelets and cellulose. Verrucous occurs mainly on the atrial surface of the mitral valve and the ventricular surface of the aortic valve. The reason is that the inflammation of the valve affects the endothelial cells and damages it. Frequently subjected to friction and blood flow impact, the damaged endothelial cells are shed, and the collagen under the endothelium is exposed, resulting in thrombosis. Sometimes, there is thrombosis in the left atrium wall. In the late stage of the lesion, fibrosis occurred in the subendocardial lesions, and warts also became organic. Because rheumatism often recurs, scar formation is increasing. The intima of the heart wall can be thickened, rough, and shrunken, especially the posterior wall of the left atrium, which is called McCallum’s patch. Due to repeated attacks and organization of the heart valve, a large amount of connective tissue hyperplasia results in thickening, curling, shortening, and calcification of the valve. Adhesion and fibrosis may occur between the leaflets, and the tendon thickens and shortens, resulting in chronic formation. Heart valve disease.   2. Rheumatic myocarditis & nbsp. Rheumatic myocarditis (rheumaticmyocarditis) mainly involves myocardial interstitial connective tissue. The connective tissue adjacent to the myocardial arterioles undergo cellulose-like necrosis, which then forms Aschoff bodies. The corpuscles are diffusely or locally distributed, vary in size, and are mostly fusiform, most commonly in the posterior wall of the left ventricle, ventricular septum, left atrium, and left atrial appendage. Later, fibrosis occurred in the corpuscle, forming a fusiform scar.  Sometimes in children, the exudative lesions are particularly obvious, the myocardial interstitium has obvious edema and diffuse inflammatory cell infiltration. Severe cases often cause cardiac insufficiency.  Rheumatic myocarditis can often affect myocardial contractility, clinically manifested as a rapid heartbeat, the first heart is low and blunt, and severe cases can lead to cardiac insufficiency. The prolonged P-R interval is common on electrocardiogram, which may be caused by the lesion affecting the atrioventricular node or vagus nerve excitation.   3. Rheumatic pericarditis & nbsp. Rheumatic disease, the pericardium is almost always involved, but clinically, only 15% of rheumatic pericarditis (rheumaticpericarditis) cases are diagnosed. The lesions mainly involve the pericardial visceral layer, presenting serous or serous cellulose inflammation, and the epicardial connective tissue may undergo cellulose-like degeneration. There may be a large amount of serous effusion (pericardial effusion) in the pericardial cavity. Percussion expanded to the left and right, the heart sounds were distant during auscultation, X-ray examination showed that the heart was pear-shaped. When a large amount of fibrin oozes out, the cellulose on the surface of the epicardium becomes fluffy due to the heart’s continuous pulsation, which is called corvillosum. During the recovery period, the slurry is gradually absorbed, and most of the cellulose is dissolved and absorbed, and a small part of it is organized, which causes partial adhesion of the pericardium’s dirty and wall layers. Very few cases can completely heal, forming constrictive pericarditis ( consrictivepericarditis).  Second, rheumatoid arthritis  About 75% of patients with rheumatic fever develop rheumatic arthritis early. Often involves the mark

The big head doll incident repeats itself, the problem milk powder reappears, what is the reason for repeated prohibition

A baby-friendly maternal and infant store in Yongxing County, Hunan, suspected that the “peramine-sensitive” protein solid beverage was sold as special medical milk powder. As a result, many children were diagnosed with malnutrition as rickets, and some children even showed the “big head doll” characteristic. The hospital’s diagnosis showed that it was stunted. This incident was so hot that it reminded people of the incidents of “Sanlu milk powder” and “Fuyang milk powder”. These two major events that shocked the country more than ten years ago have destroyed so many flowers of the motherland. It is still a pain in the public’s heart. Today, seeing “big head dolls” is shocking and heartbreaking. This “Bemin” product has a solid drink on the label. The State Administration of Market Supervision pointed out that solid beverages are ordinary foods, not infant formula milk powder, nor special medical formula foods, and their protein and nutrient contents are much lower than infant formula milk powder and special medical formula foods. Unscrupulous merchants and salespersons preached to parents in front of their parents that this is equivalent to milk powder, suitable for children with milk allergies. This matter can actually be traced back to last year. In July 2019, the People ’s Daily published a long-term survey “Reporters go through 4 provinces and 5 cities, tracking Yaledi moderately hydrolyzed protein formula powder-how does the fake formula powder flow into the market?” 》 This report involves some areas in Hunan. In 2019, Chenzhou First Hospital issued a “solid protein drink” medicine list to parents, and the media also reported on this. Xinhua News Agency reported on December 28, 2019 that the two doctors involved in Chenzhou First People’s Hospital had been suspended for one year, and the convenience pharmacy of the hospital had been shut down as required by the municipal party committee. Whether it is a mother and baby store, a shopping guide, or some doctors in Chenzhou First Hospital, do you say they can’t understand the difference between solid drinks and milk powder? To put it bluntly, it is driven by interests, and the performance of desire and desire is to take advantage of the lack of knowledge of a few parents in this area. Children’s affairs are all big things. Some people blame parents for this matter. Both solid drinks and milk powder are indistinguishable. You should know that there are different kinds of milk powder on the market. If you do n’t do your homework in playing a word game, parents really do n’t understand it at all, and you can only unilaterally trust the introductions of mother and baby stores and doctors. The crisis of trust between people is built on this negative thing. Why do things like this happen in China so often, relying on parents to be vigilant and selling products with a conscience can put an end? Impossible. In the final analysis, it is still a question of supervision. Investigate things every time something goes wrong, and always do blind sheep repairs. Should the regulatory authorities start from the source? Infant milk powder should be the same as medicines. It must be sold in a qualified place, and the sales staff must also be trained, just like pharmacies need pharmacists. Moreover, once a problem is found, the person involved should be severely punished and held criminally responsible. On May 13th, Hunan Chenzhou Market Supervision Administration and Health Committee responded to the progress of handling the case of Chenzhou Children’s Hospital doctors recommending the purchase of “Beminamine”. The incident was characterized as false publicity and penalties have been imposed on the enterprises involved Letter of decision; the enterprise will compensate the family of the victim in the manner of refunding one compensation and three compensation. The patient has been arranged for a medical examination, and the doctor in question is suspended for one year. For this kind of treatment, it is estimated that few people will be satisfied. Speaking of severe punishment, the result is like a fist raised high, but fell gently. The family of the victim only received compensation for fake one compensation and three compensation, but this was related to the child’s health and future. I hope that the supervision will be more perfect, the law will be more sound, the tragedy will not be repeated, and the children will be less hurt.

Spontaneous intestinal perforation is a serious complication of allergic purpura!

Xiebeilu studio WeChat add369456 Henoch-Schonlein purpura is a kind of vascular responsive disease in children, due to antigen-antibody compound. The deposits deposit on the walls of blood vessels, causing widespread capillary vasculitis and even necrotizing systemic small vessel vasculitis, which eventually leads to bleeding and edema of multiple tissues throughout the body. Digestive system involvement now appears to be common, and 2/3 of children with allergic purpura have gastrointestinal symptoms. The cause of intra-abdominal symptoms is bleeding and edema under the mucous membranes and serosa. Spontaneous intestinal perforation is considered to be one of the most serious intra-abdominal complications of Henoch-Schonlein purpura. It is an important cause of death in Henoch-Schonlein purpura. The incidence rate is less than 0.1%. Its pathogenesis is vasculitis leading to thrombosis and continuous serious The ischemia leads to thickening and necrosis of the entire intestinal wall and eventually perforation. The age of onset is often lower than the average age of purpura. The specific reason is not completely clear, and it may be related to the poor constitution of young children and the development of children’s immune system with age. The small intestine is the most common perforation location, with statistics accounting for 64.7%, and reports of perforation in the stomach, duodenum, and large intestine. Perforation is usually single, but there are many reports of perforation. Until the 1970s, the mortality of allergic purpura with spontaneous intestinal perforation was almost 100%. Since then, correct understanding and surgical treatment have improved survival rates. Spontaneous intestinal perforation has typical manifestations of chemical peritonitis, but because children often have obvious abdominal distension before perforation, it is difficult to diagnose by clinical signs alone, and auxiliary examination is very important. Ultrasound and CT can be used to confirm the involvement of the intestinal tract, show the thickening of the intestinal wall and hematoma, and the progress of the intestinal involvement. A series of ultrasound can prove whether the thickening of the intestinal wall has subsided or worsened to show the progress of gastrointestinal involvement, and has become a good clinical aid. Regarding the progress of intra-abdominal involvement of purpura, B-ultrasound has been found to have 100% sensitivity and specificity. In two independent large-scale studies, it can detect early intestinal edema and gas intestinal wall, which are mostly bead-like Single gas is rare for gas accumulation. Abdominal upright film is a classic examination to diagnose digestive tract perforation. In our case, the diagnosis was confirmed by CT, B-ultrasound and abdominal radiograph. Since the risk of spontaneous intestinal perforation is extremely high, once a case of suspected spontaneous intestinal perforation is found, surgical exploration is required as soon as possible. The application of glucocorticoids is also one of the possible causes of intestinal perforation. At present, this possibility has only been discussed in relevant literature reports. There is no definitive conclusion and further research is needed. In conclusion, spontaneous intestinal perforation is a serious complication of allergic purpura, and delayed diagnosis and treatment often result in death. Early diagnosis and surgery are necessary.