Shi Shurong’s medical words: Will a large number of blood transfusions cause thrombocytopenia? How is this going?

Blood transfusion is mainly an emergency treatment measure commonly used to treat excessive blood loss or severe anemia. For some patients with blood diseases, blood transfusions are also often required. According to most people’s thinking, blood transfusions input a large number of various cellular components required by the body, including blood coagulation factors and platelets. The purpose is to ensure the normal function of hemostasis. May it cause bleeding? Director Shi Shurong’s micro-signal zkxk9999 blood transfusions are generally from the blood in the hospital blood bank. Clinical data shows that it is not uncommon for thrombocytopenia to occur when a large amount of blood is input into the blood. What is the reason? Why do massive blood transfusions cause thrombocytopenia? 1. Blood collection by general methods can cause platelets to adhere and condense on the surface of foreign bodies and be destroyed. The blood bank exceeds 48 hours, and in principle there are no platelets that can survive for hemostasis. Amplified volume of blood transfusion (such as continuous transfusion of 5000 ml of blood within 48 hours), the platelet will definitely be reduced; if the amount of blood stored in the blood reaches 7000 ml, it may bleed. When children are treated with blood exchange therapy for certain diseases, if all Using stock blood can also cause the same consequences. 2. Thrombocytopenia caused by transfusion of incompatible blood. It is currently believed that this condition is caused by disseminated intravascular coagulation, which increases platelet consumption. 3. Purpura after blood transfusion. Thrombocytopenic purpura is mainly caused by changes in the body’s immune function. This disease usually occurs in middle-aged women who have a thrombocytopenia a week after blood transfusion, bleeding of skin and mucous membranes, and even the risk of intracranial hemorrhage. Generally, fresh blood or plasma is effective. 4. Repeated blood transfusion produces anti-platelet antibodies. After 50 blood transfusions, 25% to 50% of the patients’ platelet transfusion soon disappeared. This is because the production of anti-platelet antibodies shortens the life of platelets. In addition, if it is only to increase a certain component in the blood, it is not necessary to transfuse whole blood. For example, to concentrate the platelets alone, the concentrated platelets can be input separately. Leukopenia patients can enter leukocyte concentrate when they cause infection. There are also plasma and plasma protein products, granulocytes, red blood cells, etc., which can be selected according to the needs of patients. Therefore, it is very likely that platelets will decrease after blood transfusion. Through the above explanation, I hope to help you have some understanding of the common knowledge of blood transfusion. When blood transfusion is necessary, try to input fresh blood or plasma. For more thrombocytopenia disease knowledge or patient help, please pay attention to WeChat public number: xxbjs75