Good pregnancy case|Sorrow and joy, the door to fortunate pregnancy finally opens~

Don’t talk lightly about who you are paying and persisting for. In fact, the ultimate beneficiary of all your contributions and persistence is yourself. Life is a solitary practice that has nothing to do with anyone. This is a path of sadness and happiness. There will be a gift at the end of the road, waiting for you! Help more families who are struggling to walk in the dark see the light, gather strength, and move forward bravely. Good pregnancy case △Case introduction Good pregnant mother: Ms. Liu Treatment difficulties: bilateral fallopian tube removal, poor endometrium Basic situation: marriage After 5 years of non-pregnancy, severe water accumulation in the fallopian tubes, and endometrial adhesions Attending physician: Yang Weimin rashly decided to bury the root cause. I was married at the age of 24. At that time, my husband and my husband were both in a rising career period and wanted to have a baby a few years later. I discovered an unexpected pregnancy a year after marriage. I am a very strong woman in my career, and I don’t want to delay work because of my children. After consideration, I ended up having an abortion under the pressure of my family. I did not expect that this miscarriage would cause so much trouble for future pregnancy preparations. In the fourth year of marriage, my husband and I started a “personal creation project” after a relatively satisfactory work situation. For more than half a year, I have basically used all the various fertility coups I can understand. I monitor my body temperature every day, monitor ovulation every month, and have sex with my husband scientifically, but I still haven’t gotten pregnant. I found the problem and started the test tube road. In 2018, my husband and I went to a tertiary hospital in the city for an examination. The results showed that endometrial adhesions and hydrosalpinx. Infertility was caused by these two reasons. This was also the last abortion. The sequelae of surgery. Considering our age and our own problems, my husband and I decided to do test tubes. Who knows, there are twists and turns on the road to IVF. The doctor recommends that the eggs be retrieved first, and then the uterine adhesions and hydrosalpinx problems should be dealt with, and transplantation should be performed after the condition improves. In October, I collected 8 eggs from the hospital and got 6 transplantable embryos. Hysteroscopic adhesion separation was performed first, and the hydrosalpinx was more serious. If the reflux of the fluid would affect the embryo implantation, a bilateral salpingectomy was performed. Two transplants were performed in the second year, and none of them became pregnant. Thanks to the doctor, I am very frustrated because there is no good news after I have been tossing for so long. My mood fell to the bottom for a while, and then I asked more about it. In October 2019, we came to the Hebei Reproductive and Obstetrics Hospital. Director Yang Weimin of the Department of Reproductive Medicine received us. Director Yang checked my case data and decided to use the excellent plan for IVF treatment. 12 eggs were harvested, 10 were normally fertilized, 2 were frozen D3 embryos, and the remaining 6 were formed after blastocyst culture Blastocysts, a total of 8 transferable embryos were obtained. In December, the hormone replacement cycle was used for FET treatment, and two 4AB and 5BB blastocysts were transplanted. She was not pregnant. Taking into account that the condition of the endometrium has been poor, after the epidemic, Director Yang decided to adopt a sequential transplantation method to transplant two embryos into my body in April 2020. The blood HCG105760.5miu/ml was 28 days after the operation. Cashmere double sheep, twin live births!

Contraceptive guide, just read this one!

Contraception is a unique behavior of human beings. It has been popular for thousands of years. But the previous method of contraception was not a small secretion, it is really hard to say. For example, the ancient Egyptians used pomegranate seeds mixed with paraffin to make cones, and they knew that the user experience was definitely not good; or if lemon was stuffed into the vagina, it worked, but the stimulation was really stimulating. &nbsp.For example, oriental women take mercury, lead, arsenic and other toxic substances to achieve the contraceptive effect. “One cup for tomorrow, one cup for death.” At first glance, they want to poison the fetus and avoid pregnancy, but they are actually harming themselves. These toxic substances may cause women to become infertile for life, or even poison themselves. Of course, there are also a series of contraceptive measures such as crocodile papa, mule earwax, weasel testicles, musk, weasel testicles, spider sperm repellent, etc. have been invented. It is a different matter if they are not useful. It is said that the ancient Chinese used fish swim bladder to make condoms, as well as sheep intestines to make condoms. If you are interested in children’s shoes, you can search which museum collections are available. When you are free, you can check it out and add some useless knowledge. There is also said that it is made of pig bladder. Although no one has seen the real thing, Xiao Mi still can’t help but feel a chill. Uh… Throughout the history of human contraception, we can see that almost all contraceptive measures are Used on women, and the wonderful contraceptive method mentioned above is simply the best way to harm women! Until the end of the 15th century, the outbreak of syphilis created a “suit”-the lamb cecal condom. Its appearance ended the sexual persecution of women. &nbsp.[Strange knowledge points added] In the late 17th century, a British physician, Joseph Condom, cut the cecum of a lamb to an appropriate length, then dried it, and then made it with fat and wheat bran Soft until it becomes a thin rubber-like shape, a condom is made. Condom (Condom) is named after its inventor Joseph Condom (Joseph Condom). Different from modern condoms, the “cecal sleeve” is recyclable, three years new, three years old, and another three years of stitching. Of course, the ancient Romans were still clever and invented a contraceptive product called “bronze cervical pad”. Because of its good contraceptive effect, it has been used today and has gradually evolved into today’s contraceptive ring. &nbsp. The contraceptive mechanism of the intrauterine contraceptive ring (IUD) The intrauterine contraceptive device is a safe, effective, economical, simple and reversible contraceptive tool. It is still the main contraceptive method for women of childbearing age in my country. However, the contraceptive mechanism is generally very complicated, and it has not yet been fully understood. The main principles are as follows: Toxic effects on sperm and embryos・Compression produces inflammatory reactions that are toxic to embryos, and at the same time produces a large number of phagocytes covering the endometrium, affecting the implantation of fertilized eggs, phagocytosing sperm and affecting embryo development; ・Copper Ions have a toxic sperm-killing effect, so that sperm cannot be energized. Interference with implantation・Long-term foreign body stimulation damages the endometrium, produces an inflammatory response, releases prostaglandins, changes fallopian tube peristalsis, and hinders the simultaneous implantation of fertilized eggs and endometrial development; ・Activation of ischemic endometrium and phagocytes Fibrinolytic enzyme dissolves and absorbs blastocysts; ・Toxic effects of copper ions: spermicide, affects the normal metabolism of endometrial cells, hinders fertilized egg implantation and embryo development. Levonorgestrel IUD・inhibits ovulation;・changes cervical mucus It is not conducive to sperm penetration. Indomethacin IUD・ inhibits the synthesis of prostaglandins, reduces the contraction of the uterus and reduces the bleeding pain and other uncomfortable reactions after ring placement. In addition to the contraceptive ring, what other contraceptive measures can I choose? &nbsp. Informed choice of contraceptive methods is an important part of quality family planning services. It is still necessary for women of childbearing age to choose appropriate, safe and effective contraceptive methods according to their own characteristics and different periods! Conventional recommendations are as follows during the wedding period. Young couples have not yet given birth, and should choose a contraceptive method that is convenient to use and does not affect fertility. For example, compound short-acting contraceptives, male condoms, female contraceptive suppositories, and female contraceptive membranes. However, in vitro excretion, long-acting contraceptives or repeated use of emergency contraceptives are not recommended during the safe period. Breastfeeding&nbsp. Under the principle of not affecting breast milk and infant health, it is recommended to use male condoms and single progesterone

I want to go to the beach in the hot summer. How can I delay my menstruation for a few days?

In the hot summer, travel and the sea are more suitable! But if swimming meets “Auntie”, your travel experience will be greatly reduced. “Big Aunt” will not come, you will be infected with anxiety; “Big Aunt” may also bring you troubles on time, because maybe you happen to have college entrance examinations, competitions, travels, weddings and other activities during this time, do not want ” “Auntie” come to disturb, I hope she can come later. Then let Brother Miao come and talk to “Auntie”, let her postpone it a bit! Menstruation is the periodic shedding and bleeding of the endometrium under the influence of hormones. To put it simply, the endometrium is affected by estrogen and progesterone after one menstruation. The endometrium undergoes a period of proliferation→secretion, and the latter two hormones withdraw, the endometrium enters the menstrual period, and the thickened endometrium falls off. One menstruation. Therefore, to control menstruation, it is necessary to control estrogen and progesterone. Methods to postpone menstruation 1. Short-acting compound oral contraceptives (COC) should be prepared early if you want to postpone menstruation. Taking COC within 1 to 5 days after menstruation is an effective way to prolong menstruation. With the development of contraceptives, these low-dose short-acting compound contraceptives contain lower estrogen content, progesterone structure closer to natural progesterone, and lower side effects. Common COC drugs on the market are: Marvelon, Yasmin, Diane-35, etc. It is best to start to delay menstruation within 1 to 5 days from the beginning of menstruation. You can stop the medication until after your travel. 2. Oral progesterone If you want to let your aunt come later in the middle of your menstrual period, at this time the endometrium has entered the secretory period, what we need to do is oral progesterone to maintain the secretory period of the endometrium. Commonly used progesterones include medroxyprogesterone, dydrogesterone, etc. These progestins also need to be taken orally until the end of your travel, but the effect of delaying menstruation is worse than taking COC regularly in the early menstrual period. 3. Progesterone injection If your aunt is coming in less than a week, if you want to postpone it, you can choose intramuscular progesterone injection to directly increase the progesterone content in the body and try to prolong the menstrual cycle. However, the closer to normal menstrual cramps, the worse the effect of delaying menstruation, and intramuscular progesterone is very painful, and it may also cause some drug side effects, such as drowsiness, dizziness, and nausea. Although, at some more important moments, we are worried about the influence of menstruation and choose to take drugs to adjust or change the menstrual time, but this is only a stopgap measure, because often interferes with normal menstrual cramps, which may affect normal menstruation in the future cycle. Brother Miao warmly reminds: Women who use drugs to adjust or change the menstrual time must be under the guidance of a doctor, and avoid self-medication! If you have menstrual cramps during the medication, you should stop taking the medication.

What to check for ovulation disorders

  What to check for ovulation disorders? There are many types of female infertility diseases, and ovulation disorders are more common. Many women undergo infertility tests after infertility, and the results show ovulation disorders. Here is what to check for ovulation disorders.   There are many ways to check for ovulation disorders, and it is important to choose the method that suits you. Here are a few ways to check for ovulation disorders.  1. Measurement of basal body temperature   Generally, the temperature will rise within 2-3 days after ovulation. A small number of patients have temperature rise on the day of ovulation. BBT monitoring ovulation method can be used to measure it. It is simple and economical, but the error is large.  Second, Endometrial Examination  Affected by progesterone and ovarian estrogen, women’s endometrium has obvious changes in the middle of menstruation. The first 5-7 days of the menstrual period are changes in the late secretion period, and the endometrial examination within 12 hours of menstruation or menstruation is a proliferative change, indicating that the patient has not ovulated. 3. Ultrasound Follicle Examination Ultrasound can distinguish 2-4mm follicles. From the 9th day of the menstrual cycle, it is observed once every 1-3 days on average, and continuously observed, so that you can see that the follicle is gradually growing and Will indicate to the ovaries to move closer.  4. Cervical mucus examination   Women can still detect fern-like plant essences in the second half of menstruation, indicating that there is no ovulation phenomenon.   Warm Tips: If you check out ovulation disorders, you should actively treat them to avoid delays that may cause more serious consequences. I wish you a good pregnancy soon.

[Good pregnancy case] The transplant failed 4 times, and if you stick to it, you will get a good pregnancy

Don’t talk lightly about who you are paying and persevering for. In fact, the ultimate beneficiary of all your efforts and perseverance is yourself. Life is a solitary practice that has nothing to do with anyone. This is a path of joy and sorrow. At the end of the road there will be… a gift, waiting for you! Help more families who are struggling to walk in the dark to see the dawn, gather strength, and move forward bravely. Good pregnancy case △Case introduction Good pregnant father: Mother Chen Difficulties in treatment: thin endometrium, multiple failures of IVF Basic situation: getting pregnant at an advanced age, Two ectopic pregnancies, one history of fetal arrest, one side of fallopian tube ligation and one side resection Attending physician: Cai Liyi Case provided: Gao Hui’s unusually tortuous road to pregnancy Ms. Chen and her husband have been together in their twenties, and the two want to first After working hard for a career, I decided to have children in my 30s. I had been using contraception for ten years before marriage. Unfortunately, two ectopic pregnancies occurred and the embryos were implanted in the fallopian tube. As a last resort, the only way to get embryos by opening the fallopian tube was because the condition of the fallopian tubes was not good. After deciding to have a baby, I also had a natural pregnancy experience, but the fetus stopped after only 2 months, so I had an abortion and uterine cleaning. Ectopic pregnancy and embryo abortion, coupled with the age of more than 30 years old, Ms. Chen and her husband did not want to take risks anymore and chose to do IVF in 2016. Repeated transplantation failures. From February 16 to June 18, Ms. Chen underwent ICSI treatment in a tertiary hospital. The eggs were retrieved 3 times before and after. A total of 14 eggs were obtained, and 10 embryos were transplanted. No pregnancy occurred after 4 transplants. Four consecutive transplant failures left Ms. Chen and her husband to the bottom of their sadness and disappointment. What is rare is that the two quickly adjusted their emotions. The couple encouraged each other and decided to adjust and fight again after a year. &nbsp.&nbsp.&nbsp.Grateful to the doctor, thank you for meeting In September 2019, Ms. Chen came to Hebei Reproductive and Obstetrics Hospital by a friend, and Cai Liyi, director of the Reproductive Department, received them. Director Cai has been engaged in reproduction work in Japan for many years and has extremely rich experience in blastocyst culture. Director Cai Liyi carefully understood Ms. Chen’s physical condition and pregnancy experience, and determined that IVF treatment was carried out with an excellent plan. 10 eggs were obtained, 8 were normally fertilized, 3 level 1 embryos were frozen, and the remaining embryos were cultured into 3 blastocysts. (4AA, 4CB, 4BC), a total of 6 transplantable embryos were obtained. In October, Director Cai performed FET treatment with a hormone replacement cycle and transplanted two blastocysts 4AA and 4BC into Ms. Chen’s body. She was not pregnant. Because Ms. Chen had had the experience of fetal arrest and uterine dysfunction before, the endometrium was thin, so she rested for half a year. I came to check in June 2020. The condition of the endometrium is still not ideal, so Director Cai performed endometrium stimulation and intrauterine perfusion to prepare the endometrium for Ms. Chen. In late June, Director Cai used the method of continuous transplantation to thaw two D3 embryos and culture them to form 2 blastocysts 4AB and 5CB, which were transplanted into Ms. Chen’s body twice on the 20th and 21st. The blood HCG was greater than 3068.0mIU/ml on the 14th day after the operation, and the blood HCG on the 28th day after the operation was 114962.00mIU/ml. B-ultrasound showed intrauterine pregnancy, single live birth! Four transplants failed, and finally a good pregnancy came in the fifth time! Keep going, laugh at life, and live up to expectations one day!

Female self-defense system

The coordinate position of the female’s external genitalia is special, and she has been harassed by the two neighbors (urethra, anus) for a long time, and her living environment is relatively harsh. The female vulva and vagina are places for sex and childbirth. They are the openings through which the female internal reproductive organs communicate with the outside world. Therefore, they are more susceptible to damage and easily disrupted by external pathogenic factors. But a female friend is a powerful creature that loses two or two blood every month from the beginning of development…So…Don’t ignore the natural defense function of the female vulva and reproductive tract. Therefore, under normal circumstances, the genital tract infection will not be caused by the invasion of a small amount of pathogens. This powerful natural defense function is manifested in the following aspects: ①The large and small labia and the labia minora close together, like two doors, forming a physical barrier, semi-isolating the vaginal opening and urethral opening from the outside world, effectively preventing the entry of dirt Vagina and urethra. ②Women’s pelvic floor muscles and vaginal opening are usually closed due to the action of the pelvic floor muscles. The front and back walls of the vagina are close together to close the lumen and prevent the intrusion of external pollutants. But for postpartum women, the vaginal wall is relatively loose, so this defense function of the postpartum women is weakened. ③The body’s mucosal immune barrier When pathogenic microorganisms invade the body from the skin or mucosa, they can cause the body’s immune response. One mechanism is that leukocytes escape from blood vessels and gather around pathogenic microorganisms to swallow pathogens; the other mechanism is The invaded tissue produces autoantibodies, which have a specific immune defense effect against local infection. ④Vaginal self-purification The normal vagina is not sterile, but there are many different kinds of bacteria, but these bacteria are the indigenous people of the vagina and usually do not cause disease. This is because the vaginal epithelial cells are rich in glycogen. Under the action of a large number of vaginal bacilli in the vagina, these glycogen are broken down into lactic acid, so that the vagina maintains a normal slightly acidic environment, and the pH value is kept below 4.5. The pathogens that are suitable for growth in alkaline environment are inhibited, which is the self-purification effect of vagina. ⑤The role of sex hormones Under the action of the sex hormones secreted by the ovaries, on the one hand, the endometrium is periodically shed, resulting in menstruation, so that pathogens invading the uterine cavity can be eliminated with the discharge of the endometrium; at the same time, the new endometrium in the uterus The growth is also not conducive to the rooting and reproduction of pathogenic bacteria. On the other hand, the mucus secreted by the cervical mucosa glands forms a mucus plug, which blocks the cervical canal and isolates the uterine cavity from the external environment, which is of great significance for preventing the ascending infection of bacteria. Usually the internal cervix is ​​also closed, which can also prevent the invasion of pathogens. However, these self-defense functions are often affected by childbirth, menstruation, certain chronic diseases and surgery on reproductive organs, and unclean sex life. During childbirth, the fetus is squeezed out of the cervix. When passing through the vagina, it will inevitably damage the vagina and cervix to varying degrees, separate the labia, and even tear the perineum, which weakens their natural barrier function. This relative of menstruation, in a sense, has the function of “cleaning”, but the wounds and menstrual blood formed by the periodic exfoliation of the endometrium will change the acidic environment in the vagina during discharge, thus weakening the local area. Resistance. If you don’t pay attention to menstrual hygiene, infections can easily occur. In particular, it should be noted that unclean sex can cause pathogens and various dirt from the penis to directly pass through the natural barrier and be sent to the deepest part of the female genital tract, especially during menstrual and puerperal intercourse, which are more likely to cause women Inflammation of reproductive organs and pelvic infections. Therefore, one must not be sloppy when abstinence.

Cheng Yahui replied: Menstruation is low and dark, is it a disease?

For women, menstruation is something to love and hate. Sometimes the amount is large, sometimes the amount is small, sometimes bright red and sometimes dark red. These menstrual changes affect women’s bodies and affect the hearts of sisters. According to Dr. Cheng Yahui from Beijing Weiren Nursing Hospital: Many patients who came to the hospital always said: “My menstruation is too little”, “How can my menstruation become dark”&nbsp.&nbsp. What’s more, “My menstruation is dark and dark.” Less”…&nbsp.   Director Cheng gave several explanations for the difference in menstrual color and menstrual volume, so that patients and friends can intuitively understand their physical condition.  Before understanding menstrual abnormalities, you need to understand what normal menstruation is?   Normal menstruation means that the time and amount of menstruation are normal.   1. The first day of menstrual bleeding is the beginning of the menstrual cycle, and the interval between the first day of two menstruation is called a menstrual cycle. It is generally 21-35 days, and the average is 28 days, which means that the week before and after 28 days is normal.  2. The duration of each menstrual period is called menstruation, usually 2-8 days, with an average of 6 days.  3. Menstrual volume is the total blood loss in one menstrual period. Normal menstruation is 20-60ml, more than 80ml is menorrhagia, and generally less than 5ml is menorrhagia. Menstrual volume is not comparable, and varies from person to person. As long as it is within the normal range, don’t envy others more than you.  A female patient asked why the menstrual flow decreased?   The problem of low menstruation can be said to trouble many women. There is a kind of people who are as few as always from the beginning to the present, and there is a kind of people who were normal and are now rare. So how do these menorrhagia cause?    The first type of person: As always, the possible reason is the malformation of the development of the reproductive tract, which makes the menstrual blood incomplete or incompletely discharged, resulting in decreased menstrual flow.  The second type of person: ➤Recent oral medications: taking contraceptives or psychotropic drugs can reduce menstrual flow. ➤Endometrial damage: Excessive abortion and intraoperative curettage can damage the endometrium, resulting in less menstrual discharge. ➤Reproductive endocrine abnormalities: ovarian function declines, the estrogen produced by the ovaries is not enough to stimulate the full proliferation of the endometrium, and menstrual flow will decrease. ➤Others: Nutritional factors, mental factors, and exercise factors may all cause menstrual reduction.   In addition, the director said that endocrine diseases such as hyperprolactinemia, polycystic ovary syndrome, and abnormal thyroid function can all be the cause of menstrual reduction.   What should I do with low menstrual flow?    Why is low menstrual flow so worrying? Endometrial damage or adhesion may cause infertility, while decreased estrogen may cause bone, metabolism and other additional problems. Since it is so terrible, what should we do?    1. First, make a diagnosis: gynecological examination, gynecological ultrasound, multiple hormone examinations, and if necessary, diagnostic curettage or hysteroscopy.  2. The cause is diagnosed, and then the symptomatic treatment: For different reasons, the correct medicine can be prescribed. ➤Oral contraceptives or intrauterine devices: lead to reduced menstrual flow, which can change the method of contraception. ➤Endometrial damage: women of childbearing age should minimize abortion to avoid endometrial damage. ➤Ovarian function decline: combined Chinese and Western medicine to activate the ovaries Function, restore normal menstruation. ➤Polycystic ovary syndrome: Symptomatic application of drugs for polycystic ovary syndrome to restore normal menstruation.  Some patients also asked: Black menstrual blood is a disease?   Director Cheng Yahui said: Not necessarily.   Many people come to the clinic because the menstrual color is not normal, but it is just a false alarm. The components of menstruation include endometrial fragments, cervical mucus, shedding vaginal epithelial cells, inflammatory cells, etc., which appear dark red. When the amount of menstruation is low, it is like a fast-drying creek, flowing slowly, it is easy to accumulate in the body and delay the discharge. The hemoglobin in the blood that has not been discharged for a long time is oxidized, and the color will turn black. Or menstruation begins, At the end, the flow rate of menstrual blood slows down, and the weakly alkaline blood stays in the weakly acidic vagina for a long time and the color will become darker.   When menstruation is heavy, it pours out like a flood, and the menstruation is discharged in a short time, and the color is brighter red. Due to the dissolving effect of plasmin on fibrin, it will not dissolve in the case of heavy or fast menstrual blood, and blood clots will appear, which will also make menstrual blood look darker. &nbsp.(Night) This time I will definitely not miss it. Finally, Director Cheng Yahui analyzed that the amount of menstruation is not an indicator of comparison. As long as it is within the normal range, we will not

Uterine cavity preparation before embryo transfer

In the process of IVF treatment, good seeds (high-quality embryos) and good soil (uterine environment) are the two key links for successful conception. How to improve the intrauterine environment, increase endometrial receptivity, and increase The success rate of IVF is one of the goals that clinicians are pursuing. People come up with various plans to prepare the uterine cavity for embryo transfer. Let us learn about the common methods currently available.  The success of IVF technology depends on embryo quality and endometrial receptivity. With the continuous development of assisted reproductive technology, the rate of obtaining high-quality embryos has been greatly improved, but the implantation rate is still relatively low. At present, the implantation rate of embryos on the third day is only 35%, and 2/3 of the embryos transferred are The inner membrane is rejected or lost. Synchronizing the development of the embryo and transforming it into the endometrium that is receptive to the embryo in time is a key step for embryo implantation.   Therefore, before the embryo transfer, doctors have come up with many ways to prepare the uterine cavity, hoping to increase the success rate by “cleaning the house” and “turning over the soil”. What are the methods to prepare the uterine cavity before transplantation?   1. Uterine cavity preparation. Since embryo implantation is an invasive and traumatic process, proper scraping and stimulation of the endometrium before transplantation may stimulate the endometrium The local immune response makes it easy to accept embryos. It can be performed during the luteal phase of the previous cycle, early menstruation, or even on the day of egg retrieval. Generally, use a probe, a disposable suction pad, or a small curette to gently stimulate the uterine cavity, without requiring a full scrape. Because it cannot visualize the shape and pathological changes of the uterine cavity, it has a certain degree of blindness, so it is suitable for people who have not found abnormalities in the uterine cavity by ultrasound. 2. Hysteroscopy is very important to evaluate the shape of the uterine cavity before IVF treatment. Hysteroscopy can directly and comprehensively observe the lesions of the endometrium and the morphology of the uterine cavity, and can process the diseased endometrium. For example, polyp curettage and separation of intimal adhesions can effectively improve IVF pregnancy rate, which is a common clinical examination and operation. Clinical studies have also found that the “soil loosening” (finishing) under hysteroscopy is significantly better than blindly scraping and finishing the endometrium. 3. Laparoscopy: Observe the pelvic organs under laparoscopy. For lesions with moderate to severe hydrosalpinx, the diseased fallopian tube can be blocked or removed, which can effectively prevent the backflow of hydrosalpinx from affecting the uterine cavity and improve embryonic performance. The success rate of the bed reduces the probability of miscarriage. For patients with endometriosis, the lesion can be burnt and washed to reduce the interference of abnormal cytokines secreted by the ectopic lesion on the planting environment. It can also find lesions that cannot be detected by ordinary clinical examinations, such as pelvic tuberculosis. 4. Fallopian tube sticky blockage The fallopian tube is blocked with a sticky block. It is suitable for cases with hydrosalpinx but severe pelvic adhesions, but laparoscopic surgery is difficult, or the ovarian function is significantly reduced. The pelvic cavity and surgery may affect the blood and further reduce the ovarian function However, the influence of the sticky block on the embryo during the operation is uncertain, and the accumulation of water in the fallopian tube cannot be eliminated. 5. Uterine cavity perfusion is currently commonly used in clinical practice such as HCG (chorionic gonadotropin), autologous lymphocytes, granulocyte colony stimulating factor and other perfusion schemes. HCG uterine perfusion is commonly used, but its clinical efficacy is uncertain, and some are considered effective. Some are not considered effective. If there is no other way, you can also try.   The above inspections can be used alone or in combination. For example, in cases of hydrosalpinx combined with endometrial lesions, combined hysteroscopy and laparoscopy can be used to solve two problems at the same time. Due to the different purposes of the examination, the suitable people are also different, so blind treatment is not allowed. For people with lesions in the uterine cavity by ultrasound, there is no doubt about the efficacy of hysteroscopy, but it is questionable whether hysteroscopy is a necessary examination item for all IVF populations, and when it is carried out is also very different.   In any case, I wish all infertile patients can get what they want and get pregnant successfully.