Is systemic lupus erythematosus inherited?

At this stage, the prevalence of systemic lupus erythematosus has shown a gradual increase trend, and many people have this type of disease. Lupus erythematosus is very harmful to the human body. If treatment is not carried out in time, it may cause life threats. Therefore, many people are very concerned about whether lupus erythematosus is inherited. Will systemic lupus erythematosus be genetically inherited? &nbsp. Systemic lupus erythematosus (SLE) is an inflammatory connective tissue disease that affects multiple internal organs in young women. The initial, mild and atypical cases are increasing. Some critically ill patients (except those with diffuse proliferative glomerulonephritis), sometimes can relieve themselves. Some patients have a “transient” onset, and the symptoms can completely subside after a few months of brief history of present illness. Many clinical epidemiological investigations of genetic genetics have confirmed that lupus erythematosus has a certain genetic genetic trend. Everyone finds that the prevalence of collaterals in patients with lupus erythematosus is 5-12%, and the prevalence in fraternal spasms is 23-69%. This indicates that genetic inheritance is related to the occurrence of the disease. From the perspective of genetic inheritance On the short arm of human sex chromosome No. 6, there is something called Human Leukocyte Counting Antigen (HLA), which is composed of a variety of genetic genes and is closely related to human genetic inheritance. HLA is divided into Class I, Class II, and Class III genetic genes. Studies have found that the molecular structure of HLA-II is closely related to the susceptibility genes of lupus erythematosus and the production of various autoantibodies during the whole process of lupus erythematosus. According to the test, those who carry HLA-DR2 and HLA-DR3 genes The prevalence of lupus erythematosus is much higher than that of all normal control groups, which also confirms the genetic trend of this disease. &nbsp. However, in clinical medicine, we also see that many patients with lupus erythematosus have children who are very healthy and do not suffer from lupus erythematosus. In fact, the cause of lupus erythematosus is the result of a variety of comprehensive factors including infection, endocrine and natural environmental influences. It should be emphasized that clinical medicine finds that mental factors are a cause and aggravation of the disease. Very critical reason. Therefore, it can only be said that lupus erythematosus has a genetic inheritance trend, not a genetic disease. Therefore, patients with lupus erythematosus do not have to worry too much about the genetic inheritance of their own disease to their children. Systemic lupus erythematosus is a multi-element (genetic inheritance, estrogen, natural environment, infection, drugs, immune response) and other specific immune system diseases. This disease is common in young ladies and may be related to the level of estrogen in young ladies. Although the cause of the disease has not been fully established at this stage. However, most medical scholars widely believe that the pathogenesis of lupus erythematosus is that the total number and function of immune-specific somatic cells are disordered, which leads to immune neurological dysfunction. The body produces many autoantibodies and causes immune complexes (type III) and cytotoxicity. (Type Ⅱ) Hypersensitivity, which leads to widespread tissue damage and multi-system clinical manifestations. It can be known from the text that there are various causes of systemic lupus erythematosus, which are related to genetic inheritance. In addition, it is also very closely related to some infections, natural environment, drugs, and immune responses, such as erythema. In the case of lupus, the cause should be investigated immediately and treated immediately.

People with kidney disease are basically calculated by these three “killers”

Kidney disease is a common disease that affects the kidney function of the human body, which can lead to a decline in patient function and induce various diseases. Nephropathy can be divided into many types, according to the cause can be divided into primary nephropathy and secondary nephropathy. Kidney disease has become one of the killers of people’s health. Many people’s health has been destroyed by kidney disease. Most people do not understand the cause of their kidney disease, which brings many difficulties to the treatment of kidney disease. Therefore, we must first determine the cause of nephropathy and see what kind of nephropathy patients belong to. The treatment and prevention of nephropathy has become a subject of in-depth clinical research. To be frank: People with kidney disease are basically calculated by these three “killers” 1. Genetic factors cause some kidney diseases to be closely related to heredity, such as polycystic kidney disease, Alport syndrome, etc. It is more or less a genetic factor, and even heredity only plays a catalytic role. Clinically, the occurrence of diabetic nephropathy is closely related to diabetes, but the occurrence of diabetic complications is also very closely related to heredity. 2. Drug abuse Since the pharmacy, people are reluctant to go to regular hospitals to buy targeted drugs for treatment when they have kidney disease. However, due to the lack of knowledge about pharmacology, many people frequently abuse drugs. Not all drugs will bring certain toxicity to the kidneys. Such as non-steroidal anti-inflammatory drugs in Western medicine, drug abuse will only cause a slight decline in kidney function. To be frank: People with kidney disease are basically calculated by these three “killers”. 3. Daily behaviors lead to kidney disease. Daily behaviors may also lead to kidney disease, such as holding urine, long-term drinking water, poor hygiene, If you wear too little, don’t look at the details and have nothing to do with the cause of kidney disease. In fact, holding back urine, long-term lack of drinking water, and poor hygiene habits can easily lead to pyelonephritis. In addition, long-term lack of drinking water is likely to increase the risk of kidney stones. The cause of people suffering from kidney disease is also related to their body structure. In fact, the cause of nephropathy is directly related to obesity. If they are overweight, they are susceptible to obesity-related kidney disease. I am afraid that many people have never thought of the cause of this kidney disease. Female friends are more likely to have kidney disease than men, and they will be accompanied by hematuria and proteinuria. Severe diseases will directly cause kidney function damage. To be frank: People who suffer from kidney disease are basically secretly reminded by these three “killers”. If people usually like salty, greasy and spicy food, they must be restrained. Because salty foods are high in sodium, eating food is more likely to cause blood pressure to rise. Fat and cholesterol in greasy foods are high, which can easily cause hyperlipidemia. Spicy foods are irritating, such as chili peppers, causing qi deficiency and decreased immunity.

Is it related to which chromosome of microtia?

This phenomenon may be due to the existence of a chromosomal balance translocation between the couple. It is recommended that the patient’s parents can take the patient to a professional plastic surgery hospital for medical plastic surgery. The purpose of improving the image through surgical methods. And after the operation, we must pay attention to local hygiene and cleaning to prevent infection. At present, the etiology of microtia is not very clear, and no specific pathogenic factors have been found. Environmental and genetic studies have shown that there are many factors that can cause malformations: Environmental factors include biological, physical, and psychological factors Among them, the infection of pathogenic viruses in early pregnancy is easy to cause diseases, including cold virus, varicella zoster virus, etc. Of course, mothers with immune diseases and diabetes are also prone to give birth to children with small ear deformities; radiation and environmental pollution, etc. Maternal factors may be one of the causes of microtia: the use of hormones, sulfonamides, some Chinese herbal medicines, antiviral drugs, and antibiotics such as gentamicin, streptomycin, tetracycline, and levomycin in early pregnancy can be caused by chemical factors. The occurrence of disease, frequent exposure of pregnant women to tobacco and alcohol are also susceptible factors; mental stimulation at the beginning of pregnancy is also one of the predisposing factors. Genetic factors also occupy a certain proportion. Family is an important resource for studying the genetic factors of congenital microtia. In 1968, some scholars believed that the disease line was recessively inherited. In 1978, it was first reported that both mother and child suffered from unilateral microtia with an autosomal dominant inheritance. There are 7 cases of the disease in the fifth generation of a family, suggesting that the disease line is autosomal dominant with different phenotypes and low penetrance. A large-scale survey of 171 patients with microtia in 96 families believes that the disease has polygenic inheritance. In 2008, domestic scholars reported cases of morbidity and aggregation in the family. The patient is a father and daughter with the same right ear deformity, which belongs to the first-degree relatives. It is considered that genetics is an important factor. Chromosome karyotype detection found that most congenital microtia is normal, and only a few patients have chromosomal abnormalities. The current reports include: 5p chromosome deletion, 6q single sex chromosome, 8q chromosome deletion, trisomy 18, 21 ring chromosomes , 22q deletion, 22 trisomy, 47XXY. In addition, there have been reports of chromosome mosaicism, including 7 trisomy and 9 trisomy. Children’s left ear deformity is related to many reasons, such as father smoking or drinking alcohol, parents exposed to industrial chemicals during pregnancy or pregnancy, mother smoking second-hand smoke or drug abuse during pregnancy, noise or dust pollution, family inheritance and other factors, congenital Sexual deformities should be diagnosed and treated as soon as possible. & nbsp. & nbsp. & nbsp. Dr. Anbo suggested: early attention, early detection, early treatment! If you want to know more about small ear problems, you can pay attention to our public number: (ear reconstruction base) leave a message to consult and sign up; you can follow us and leave us a message; & nbsp.

There is no history of genetic disease in the family. How is the child inherited hemophilia?

The doctor asked the doctor: “The family is very healthy, why is the child diagnosed with hemophilia? “Disease: Hello, the child was diagnosed with hemophilia A shortly after birth. What I want to ask is that no one in the family has a genetic disease. Why is my child sick? Medical Answer: Hello, hemophilia is a bleeding disorder with sexual recessive inheritance. The lack of eight factors is type A, and the lack of nine factors is type B. The disease-causing genes are generally on the female X chromosome. The sex chromosomes of males are XY, while females are XX. Generally, the woman obtained the X chromosome with the disease-causing gene from her sick father, an X chromosome, and a Y chromosome, but because she got a healthy X chromosome from her mother, she did not get sick. Carrier. If the mother is the carrier, the daughter has half the chance to get the diseased X chromosome to become the carrier. The son has a 50% chance of getting one of the diseased X chromosomes from the carrier mother. According to your description, the child’s grandfather or uncle, the father or brother carrying the mother may be a patient, but due to genetic probability problems, it is not always possible to find the previous generation of patients. In addition, the disease-causing gene may be obtained due to new mutations, so that there is no patient or carrier of the previous generation. If you have any questions about this article or your condition, follow the patient’s WeChat account to get help: xueyb120

Dig deeply into the folk medicine and benefit the country

If traditional Chinese medicine is a great treasure trove of Chinese celebrities, it is the key to open Chinese civilization for thousands of years. Then it is natural that folk Chinese medicine is an indispensable part of the treasure. Digging deeper into the folk heritage of traditional Chinese medicine, there is indeed a specialty of traditional Chinese medicine and use it to promote it. There is no doubt that it is a great initiative that is worthy of ancestors and benefits the country and the people. We can’t limit and exclude only one licensed physician’s certificate as a threshold. So that a large number of Chinese medicine experts have lost the meaning of survival. In the ancient Tang and Song Dynasties, the Chinese medicine was still in bloom. Medical professionals such as Sun Simiao emerged. Why can’t our modern civilization tolerate some stupid heritage doctors? Cut your feet to fit your feet, choking to waste food. Can only seize the sesame and lose the watermelon. It is not conducive to the inheritance and development of traditional Chinese medicine, but also unfavorable to the people’s wishes. To develop traditional Chinese medicine, we must learn from the ancients and not from the ancients. We must inherit and innovate. It is a century-old plan to salvage in-depth talents who have contributed to the development of traditional Chinese medicine from generation to generation.