By observing the rheological properties of blood viscosity, flow and aggregation, red blood cell deformation and aggregation, and platelet aggregation and release, the macro and micro rheological properties of blood and blood vessels were studied. 1. Reflects the thickness of blood-hematocrit: It reflects the ratio between blood cells and plasma in the blood. Increased hematocrit indicates that the blood is thick and sticky. In addition to cerebrovascular disease, it is also seen in polycythemia. Decreased hematocrit indicates that the blood is thinner and the viscosity of the whole blood decreases accordingly, which means the body has blood loss or anemia. 2. Reflecting blood viscosity-whole blood viscosity: whole blood viscosity is changed by the change of hematocrit. Generally speaking, if the hematocrit is high, the whole blood viscosity is high. Increased whole blood viscosity indicates increased hematocrit or plasma viscosity, increased red blood cell aggregation, poor red blood cell deformability or elasticity, and hardened and rough blood vessel walls. Its increase is common in the following diseases, such as cerebrovascular disease, polycythemia, coronary heart disease, diabetes, hypertension, chronic bronchitis, vasculitis, pulmonary heart disease, active connective tissue disease, chain hemoglobinopathy, leukemia, etc. 3. Reflecting the aggregation of blood cells-red blood cell electrophoresis time: the shorter the time, the more the surface charge of red blood cells, the more dispersed the red blood cells, the less aggregation. On the contrary, if the time is longer, the surface charge is less, then the red blood cells Increasingly aggregate, causing red blood cells to form clusters and piles, increasing the viscosity of whole blood. Blood rheology examination is very important, regular physical examination to ensure good health. In fact, it’s just like taking blood. You usually need to take blood in the morning. Before taking blood, try to reduce the amount of exercise. Do not eat, keep an empty stomach, drink a small amount of water. It is best not to eat anything or drink any beverages within 12 hours, including tea.
In the initial diagnosis of patients with essential thrombocythemia, they may not even have symptoms, but they should not be underestimated, because this condition may progress slowly in the early stage, but as the condition intensifies, it will have a serious impact on the patient’s health, and even turn into acute leukemia. life. To diagnose thrombocytosis, the patient should do the following: ①Patients with severe anemia in life should change their position slowly to prevent sudden syncope. Children, elderly, and critically ill patients should add a bedside block beside the bed. The room environment should be kept hygienic and clean, especially with fresh air and suitable temperature and humidity. Patients should maintain an optimistic and positive attitude and cooperate with the doctor’s treatment, which is more conducive to the relief of the disease. ②The diet should be carried out according to the doctor’s advice, avoid excessive nutrition, the diet should be light and nutritious, and vegetables such as fungus, celery, and white radish can be eaten appropriately. When thrombocytosis patients have no blood clots or bleeding in the early stage, eat more vegetables, fruits and loose knots and soft products, drink more water, avoid spicy irritants. When bleeding, stay in bed to eliminate tension, and eat lotus joints. During the illness, eat more foods that are easy to digest and absorb, and prohibit eating puffed foods, so as not to aggravate the condition, and after recovering health, eat as little or not as possible of such foods. ③In terms of exercise, go to bed and get up early every day as much as possible. Appropriate physical exercise can enhance physical fitness and improve disease resistance. It is advisable to choose moderate exercises for proper exercise, such as walking, Tai Chi, jogging, etc. People with large spleen avoid bumps. ④ In terms of treatment, aspirin, hydroxyurea and interferon are the main western medicines for the treatment of this disease. However, the course of this disease is frequent and long-term medication is required, and side effects are inevitable. Therefore, timely combination of Chinese medicine and combination of Chinese and Western medicine are more effective. ——When thrombosis is formed, active treatment with combination of traditional Chinese and western medicine is required to prevent gangrene. For patients without bleeding and thrombosis tendency, the therapeutic effect of traditional Chinese medicine is considerable. For more patient communication help, please follow the WeChat public account [thrombocytosis patients association] xxbzd999
Sleeping should be our instinct, presumably before humans have fully evolved, just like all animals, sleep is part of life. Entering the agricultural society, we plow at sunrise and rest at sunset, which is also considered to be natural, without insomnia and staying up late. But since the advent of the industrial age, especially in recent years, nightlife has become more and more abundant, and more and more people can’t sleep because of active or passive actions. Some people have to go to night shifts to stay awake at work; some people stay up until midnight to eat and drink; some people sing and dance, often all night; some people, stress, anxiety, etc. can cause insomnia. But everyone knows that lack of sleep and insomnia are definitely not good for health. Long-term insomnia and lack of sleep can cause many diseases. Only by ensuring adequate sleep can we ensure our normal life and study. If we sleep too little, we are not energetic the next day, just like the battery is not fully charged and the engine is sluggish; but if we sleep for too long, it will also have an adverse effect on the body, so how long should we sleep every day? ? 1. Research from Peking University: Too much or too little sleep can lead to cognitive decline. A Peking University study shows that too little or too much sleep can lead to cognitive decline. A total of 20056 people were selected for the study, including 9254 participants from the United Kingdom and 10,811 participants from my country. The study found that adults sleep less than 4 hours per night and sleep more than 10 hours per night have a faster decline in cognitive scores. So, don’t think that sleeping enough every day is good for your body. The fact is that sleeping too much or too little will increase cognitive decline. 2. The latest South Korean study shows that too much sleep and too little sleep lead to obesity. A recent South Korean study found that adults sleep 7-8 hours a day. If they sleep less than 5 hours a day, compared to people who sleep 7-8 hours, The likelihood of obesity increases by 50%; if you sleep for more than 9 hours, such as people who sleep 7-8 hours a day, the likelihood of obesity increases by 12%. After obesity, there are three high risks, various cardiovascular and cerebrovascular diseases, and joint diseases will increase. Therefore, do not sleep too much, nor too little. 3. Research by Huazhong University of Science and Technology: Too much sleep and too little sleep lead to increased risk of cardiovascular disease. According to a study conducted by Huazhong University of Science and Technology, people who sleep too much or too little have an increased risk of cardiovascular and cerebrovascular diseases. Compared with people who sleep 7 hours a day, for every hour of sleep reduction, the risk of coronary heart disease increases by 7%, the risk of cerebral stroke increases by 5%, and the risk of all-cause death increases by 6%; compared with people who sleep 7 hours a day , For every additional hour of sleep, the risk of coronary heart disease increases by 5%, the risk of stroke increases by 18%, and the risk of death increases by 13%. The conclusion is that people who sleep about 7 hours a day have the lowest risk of cardiovascular and cerebrovascular diseases. 4. The European Journal of Cardiology, Sleeping too much or too little, increases the risk of myocardial infarction. The European Journal of Cardiology involves 21 countries and enrolled 116,632 people. They were followed up for an average of 7.8 years to observe sleep time and cardiovascular disease. The circumstances of death. Studies have found that compared with people who sleep 6-8 hours a day, people who sleep less than 6 hours have a 9% increase in the risk of cardiovascular and cerebrovascular diseases; if you sleep too much, sleep 8-9 hours a day, the risk of cardiovascular and cerebrovascular diseases increases by 5% , Sleep> 10 hours a day, increase the risk of cardiovascular and cerebrovascular diseases by 41%. Therefore, too much sleep and too little sleep will not only increase the risk of obesity, increase the risk of cognitive decline, but also increase the risk of cardiovascular disease, cerebrovascular disease, and even death. Insufficient sleep may lead to a decrease in the secretion of endocrine hormones such as insulin and leptin, thereby accelerating the production of obesity or diabetes, leading to an increased risk of cardiovascular and cerebrovascular diseases and an increased risk of death. Sleeping too long may be an early manifestation of certain diseases, and sleeping too long may itself be a manifestation of sub-health. In short, adequate sleep is the basis to ensure our immunity and the basis for our normal life and health; but everyone needs to understand that it is not advisable to sleep less, and it is not advisable to sleep more.
The latest report from the Chinese Center for Disease Control and Prevention, the National Nutrition Survey Database suggests that our diet has undergone tremendous changes. Over the past few decades, our living standards have undergone tremendous changes, especially the biggest changes in our diets, from not having enough food many years ago, to later being full, eating well, and even having overnutrition. Sudden changes in diet have caused more hypertension, diabetes, hyperlipidemia, and cardiovascular and cerebrovascular diseases. So what are the changes in our diet, and what are inappropriate? 1. The proportions of grains, tuber foods, and vegetables are declining. Results: From 1982 to 2012, the proportion of many of our foods was decreasing: the intake of vegetables dropped from 316 g/day to 269 g/day. Cereals, that is, foods including wheat, rice, corn, beans, etc., dropped from 509g/day to 337g/day; tuber foods, that is, sweet potatoes, potatoes, yams, lotus roots, and other foods, from 180g /Day, down to 3,6g/day; the proportion of cereals, especially coarse grains, has been reduced. As a result, people mainly rely on fine grains. The result of fine grains is that dietary fiber is reduced and vitamins are destroyed. The long-term result is an increase in the risk of cardiovascular disease. The Lancet research shows that in 2017, the global shortage of coarse grains and the relatively excessive amount of fine grains caused 2 million deaths from cardiovascular diseases. And a healthy diet encourages more beans, corn, millet, sweet potatoes, potatoes and other foods; especially vegetables need to increase the proportion. The “Dietary Guidelines for Chinese Residents” recommends 5 kinds of fresh vegetables every day. It is recommended to have vegetables in meals. The weight of vegetables should account for more than half of the daily diet, and dark vegetables should account for more than 1/2. 2. Fruits, dairy products, eggs, and nuts have increased, but still not enough. From 1982 to 2012, some of our foods have increased, but the total amount is still not enough: fruits have increased from 37 g/day to 40 g/day; Dairy products increased from 8g/day to 25g/day; eggs increased from 7g/day to 24g/day; nuts increased from 2g/day to 4g/day. These foods are relatively healthy diets that help prevent cardiovascular and cerebrovascular diseases. Although the proportion of these foods has increased, the overall intake is still low, and far below the recommendations of the Chinese Nutrition Guidelines. According to “The Lancet” statistics, in 2017, there were 2 million deaths due to insufficient fruit intake… The “Dietary Guidelines for Chinese Residents” recommends 200-400 grams of fruit per adult in my country, but the current average is only 40 Grams. The “Dietary Guidelines for Chinese Residents” recommends that people of all ages drink milk for bone health, and try to choose low-fat, skimmed milk. It is recommended to drink an average of 300ml milk per person per day, but the current average is only 25g. The “Dietary Guidelines for Chinese Residents” recommends 6 eggs per person per week. The recently released Chinese Guidelines for Healthy Lifestyle Prevention of Cardiovascular and Metabolic Diseases also recommend nuts as part of a healthy diet. It is recommended to eat 50 to 70 grams of nuts per week. 3. Excessive proportion of livestock and poultry, insufficient fish. From 1982 to 2012, we eat more and more meat: the total amount of meat increased from 53 g/day to 138 g/day; for pork, 37 g/day Day increased to 64 g/day; instead, fish decreased from 28 g/day to 24 g/day. For a healthy diet, it is necessary to control the total amount of red meat such as fat, offal and even pigs, cattle, and sheep. At the same time, it is recommended that the meat be mainly poultry, fish, and seafood. The “Chinese Residents Dietary Guidelines” recommends 40-75 grams of aquatic products per day. And we only have 24 grams; 40-50 grams per day for livestock and poultry; and we have exceeded 138 grams. Too much fat, offal, and red meat will increase the risk of hyperlipidemia and increase the risk of cardiovascular and cerebrovascular diseases. Therefore, most of us eat too much meat, especially livestock and poultry, and there is relatively little fish. In the future, we can appropriately reduce livestock and poultry meat and gradually increase fish and other aquatic products. Fourth, eating out has increased, and the oil and salt have exceeded the standard Many years ago, even if they were rich, there were few restaurants outside and nowhere to eat. Nowadays, many people eat out every week, and even more office workers eat takeout every day. From 1982 to 2012, oil and salt changed from 18 g/day to 42 g/day; salt decreased from 12.7 g/day to 10.5 g/day. Data from the China Health and Nutrition Survey shows that about 56% of Chinese people eat more than the standard of edible oil, and 72% eat more than salt.
You can usually see a lot of old people “faced red”, and they are often called “good looking”! In fact, the complexion is too ruddy, which is not necessarily a good thing for middle-aged and elderly people. It is likely to have a huge hidden health risk-polycythemia vera! Polycythemia vera is rare in normal times. Most patients may not have heard of this disease before the diagnosis, but it is one of the hidden health hazards to the middle-aged and elderly people! The so-called “hidden danger” is mainly because it is relatively hidden. Most patients find abnormal blood picture through physical examination, and then learn about it after further examination. When these symptoms appear, you need to be wary of real red! 1. In the early stage, there may be headaches, dizziness, fatigue, tinnitus, vertigo, forgetfulness and other similar neurosis symptoms. Later, there are symptoms of numbness and tingling, hyperhidrosis, visual disturbance, skin itching and peptic ulcer. 2. The patient’s skin and mucous membranes are markedly red and purple, especially cheeks, lips, tongue, ears, rhinitis, neck and upper extremities (digits and thenar). The eye conjunctiva is significantly hyperemia. 3. When the blood flow is significantly slow, especially when there is an increase in platelets, thrombosis, infarction or phlebitis may occur. Thrombosis is most common in the limbs, brain and coronary vessels. Severe neurological manifestations include symptoms caused by cerebrovascular damage such as paralysis. Hematologists tell everyone that polycythemia vera has a slow course and is not easy to detect actively. Untreated patients have a poor prognosis and a higher incidence of fatal thrombosis or bleeding complications. Therefore, if you find the above symptoms, you should Go to a regular hospital as soon as possible and take treatment measures. For more patient communication help, please follow the WeChat public account [True Red Patient Club] zkxy120
. .1 When self-driving cars are in a traffic jam. Studies have found that heart disease patients are three times more likely to have an attack when encountering traffic jams than usual. People with heart disease should avoid taking crowded buses.  . .2 When you are in a hurry to do important things. When patients with heart disease are anxious to do important tasks or complete larger tasks, their blood vessels throughout the body may spasm and contract, and the burden on the heart will increase, which may increase the chance of an acute attack.  . .3. When quickly overfeeding. Studies have found that after the human body consumes a high-fat, high-calorie diet, it will cause the body’s blood vessels to constrict, thereby increasing the chance of thrombotic diseases.  . .4. When constipation is urgent to defecate. Constipation patients must use too much force to increase the pressure on the chest cavity when they are in a hurry to defecate, so that the amount of blood returned to the heart is sharply reduced, which may induce heart disease.  . .5. Insomnia at night and irritable. A survey in the United States found that compared with people without sleep problems, people who sleep well almost every day have a 45% increase in the risk of heart disease, and those who have difficulty falling asleep have a 30% increase in heart disease. People who feel that their body is not rejuvenated after waking up have a 27% increase in heart disease.  . .6. When the temperature is too low in winter. Winter is the season of high incidence of heart disease. After cold air acts on the human body, the blood vessels constrict, the blood pressure becomes higher, and the heart rate increases, so that the burden on the heart is heavy. In addition, cold stimulation can cause spasm of the blood vessels supplying the heart (coronary blood vessels), which can cause myocardial ischemia and sometimes directly cause myocardial infarction.  . .7. When speaking in public places. Most people will be abnormally nervous or excited when giving speeches in public venues, which can cause a sudden increase in blood pressure, a surge in adrenaline levels in the body, and increase the risk of heart disease.
Polycythemia vera is a kind of myeloproliferative disease and a hematological malignancy. It is manifested as the continuous increase of red blood cells, often accompanied by increased white blood cells and platelets. However, the development of the disease is slow and the course of the disease is long, which can last for more than 10 years or even longer. To treat true red, pay attention to these three points: 1. Control the number of red blood cells. Interferon is commonly used and can also be supplemented by other oral chemotherapy drugs. 2. To control the tendency of thrombosis caused by the increase of red blood cells, you can take aspirin and other anticoagulant and blood stasis drugs. 3. If the disease is to be cured, the only way is allogeneic hematopoietic stem cell transplantation. Note for patients who choose interferon: ① . You can follow the doctor’s advice and add hepatoprotective drugs at the same time, because this drug hurts the liver. ② . When interferon is given, the first three injections usually respond, showing fever, muscle and joint pain, and you can take it orally in advance Sanlitong relieves symptoms. When interferon is used to treat this disease, the usual dose is 3 million units, subcutaneously injected once a day, and then gradually reduced according to the number of red blood cells to a long-term maintenance amount. For more patient communication help, please follow the WeChat public account [True Red Patient Club] zkxy120
Vitiligo treatment cycle is long, many patients can not see the obvious effect of the treatment, they give up treatment, or some patients go to the hospital for treatment only when the leukoplakia has a tendency to spread, and stop the treatment midway. Chongqing Dibang Vitiligo treatment doctor said that vitiligo What is the impact of interrupting treatment? 1. Weakening the effect of pre-treatment The treatment of vitiligo usually takes a while to show up. If the patient interrupts treatment at will, this may lead to abandoning the previous treatment and greatly reduce the original treatment effect. 2. Increasing the difficulty of later treatment. Some patients will easily give up the idea when multiple treatments fail. When the leukoplakia spreads to other parts of the body, or when the area rapidly expands, the difficulty of treatment will undoubtedly increase further and the cost of subsequent treatment will also increase. 3. Resistant to treatment. Chongqing Dibang vitiligo treatment doctors say that some patients are prone to resist emotions after repeated treatments without results. However, when the white spots spread to other parts of the body, or when the area expands rapidly, the treatment will undoubtedly be difficult Further increase will also increase the cost of subsequent treatment. It is worth noting that if we want to do a good job in the prevention and treatment of vitiligo, we must first pay attention to the diagnosis of vitiligo. In clinic, many patients are blindly treated, abused drugs, and experimental treatments without comprehensive professional testing, which can easily lead to patients not only unable to effectively control their condition, but even secondary damage. Therefore, testing and diagnosis before treatment is very important. Chongqing Dibang vitiligo treatment doctors said that clinical treatment shows that enhanced testing and personalized treatment in summer can effectively avoid all kinds of blind treatment and medication, significantly improve the efficacy, shorten the treatment time, control the recurrence of vitiligo, and help patients avoid detours during treatment. Cost savings.
First of all, the main function of platelets is to stop bleeding and coagulation. Then the question is, why does the increase in platelets cause bleeding symptoms? This time I will answer for everyone. Thrombocytosis is the mechanism of bleeding, which is mainly due to the number of platelets Increased, but there are defects in its functions, such as decreased platelet adhesion and aggregation, abnormal release function, decreased platelet third factor, and decreased 5-hydroxytryptamine. Some patients also have abnormal blood coagulation function, such as the decrease of fibrinogen, prothrombin, factor V, factor Ⅷ, which may be caused by excessive consumption of coagulation. At the same time, since most of the disease occurs in elderly patients, it may be combined with vascular degenerative changes, which may easily form thrombus, causing distal vascular infarction and rupture of the infarct area. In addition, due to too many platelets, activated platelets produce thromboxane, which causes a strong aggregation and release reaction of platelets, which can easily form microvascular embolism and further develop into thrombus. Primary thrombocythemia occurs in patients 50-70 years old, and the average age of onset is 60 years old. At the beginning of the onset, there are generally no obvious symptoms, and the main clinical manifestations are bleeding and thrombosis. Spontaneous bleeding is mostly bleeding from the nose, gums, and gastrointestinal mucosa; thrombosis is more common in foreign reports, but rarely in China. About 30% of patients present with functional or vasomotor symptoms, such as vascular headache, dizziness, blurred vision, burning pain in the palms and soles, peripheral numbness, and cyanosis. It can also show non-specific symptoms such as fatigue, fatigue, and insomnia. About 40% of patients may have hepatomegaly, and 80% of patients may have mild or moderate spleen enlargement. There are also about 20% of patients with this disease may have asymptomatic splenic infarction, which leads to spleen atrophy. Patients with thrombocytosis generally have a natural course, that is, the survival period, which is 7-15 years. However, if effective treatment is taken, if the platelets cannot be controlled in time and the platelets are too high, they will live at any time At the same time, some patients are prone to develop leukemia. Therefore, when the examination finds that the platelets are high, the treatment should be done in time to avoid delaying the best treatment time.
Condition description: At the beginning of last year, my mother always felt that she was not feeling well. At first she had a headache, but then she always felt very tired. She also had blood in the stool and hemoptysis one after another. So I quickly took her to the hospital for examination. During the blood test, the doctor found a significant increase in red blood cells, followed by a series of examinations such as bone marrow aspiration, and finally diagnosed as polycythemia vera. It has been more than a year since the diagnosis was made, and my mother has been taking oral hydroxyurea and interferon injections. Recently, I obviously feel that the elderly’s physical condition is not very good, but it won’t work without treatment! I don’t know what to do in the future. Is there any treatment to control the condition? Experts answer that polycythemia vera is a clonal disease of hematopoietic stem cells of unknown cause. Conventional treatment is mostly bloodletting, oral hydroxyurea, and injection interference. Vegetarian and so on. Although these treatments have a certain effect on patients, they are prone to some side effects in the long run, and even speed up the progression of the disease. In response to this situation, patients can choose to change the treatment plan, or combine medication. At present, the combination of traditional Chinese and western medicine has a good effect in the treatment of true red. Traditional Chinese medicine adopts syndrome differentiation to adjust the patient’s autoimmune function and consolidate the therapeutic effect. With western medicine treatment, further development and deterioration of the condition can be avoided. Although polycythemia vera is not a benign disease, its progress is slow. Therefore, patients should actively take treatment measures to relieve the condition as soon as possible. At the same time, prevent the disease from worsening to leukemia and myelofibrosis. For more patient communication help, please follow the WeChat public account [True Red Patient Club] zkxy120
The first-line drugs for the treatment of essential thrombocythemia are commonly hydroxyurea and interferon. Among them, interferon is mostly used for patients under the age of 40. So how does interferon treat thrombocytosis? Interferon treatment of thrombocytosis: Interferon is a cytokine that has many functions such as inhibiting cell division, regulating immunity, anti-virus and anti-tumor. Because interferon can inhibit megakaryocyte production and shorten the survival time of platelets. Therefore, interferon is also widely used in the treatment of thrombocytosis. Common interferon is usually administered by subcutaneous injection, three times a week or once every other day, the recommended dose is 3~5MU, and the course of treatment is generally 6 months. After onset of effect, the dosage and course of treatment can be adjusted appropriately according to the patient’s condition and tolerance to the drug. For patients treated with pegylated interferon [α-2a], it is recommended to inject 180μg subcutaneously once a week for one year; for patients with pegylated interferon [α-2b], it is recommended to inject 1 per week The dose is 1.0-1.5μg/kg, and the course of treatment is one year. The dosage and course of treatment of specific drugs should be appropriately adjusted according to the actual situation. Experts remind: In the early treatment process, it is recommended that patients be followed up regularly and blood routine check once a week in order to grasp the changes in the condition in real time and adjust the treatment plan in time. For patients with poor interferon treatment, it is necessary to promptly report back to the doctor, change to other treatment plans or take a combination of drugs to relieve. For more patient communication help, please pay attention to the WeChat public account [thrombocytosis patients association] xxbzd999
Thrombocytosis means that the platelet count in the blood is higher than 400X10^9/L. When the platelet count is significantly high, it is considered as essential thrombocytosis. This disease mostly occurs in middle-aged and elderly people, and there is a risk of thromboembolism, which directly endangers the lives of patients. ——In addition to thrombosis, what are the other hazards of thrombocytosis: About 20% of patients, especially young patients, are asymptomatic at the time of onset, and occasionally diagnosed with thrombocytosis and splenomegaly. About one-third of the patients presented with functional or vasomotor symptoms including vascular headache, dizziness, blurred vision, burning pain in the palms and soles, and peripheral numbness. 80% of patients may have unexplained bleeding and thrombosis and go to a doctor. Bleeding is often spontaneous and can occur repeatedly. It is common with gastrointestinal bleeding. It can also have nose, gum bleeding, hematuria, respiratory tract bleeding, skin, mucous membrane ecchymosis, but purpura is rare. Sometimes it can be found because of bleeding after surgery. Cerebral hemorrhage occasionally causes death. Myeloproliferative blood diseases are often accompanied by high platelet counts. Therefore, when the platelet count is high, we must pay attention to it and go to the hospital for examination as soon as possible. After clarifying the cause, actively carry out treatment to control the platelet count within a safe range as soon as possible. For more patient communication help, please pay attention to the WeChat public account [thrombocytosis patients association] xxbzd999
1. Single-drug principle: When people with epilepsy are treated with drugs, the single-drug principle should be adopted as much as possible. Most patients can be controlled by a single drug treatment. The combined use of anticonvulsants will not be more effective, and often increases the toxicity of the drugs, resulting in unexpected and unexplained interactions of anticonvulsants. You must be cautious about co-administration and prohibit it Use multiple anti-epileptic drugs at the same time. 2. Keep it simple: Epilepsy is usually a chronic condition. It is not only based on the blood level of anticonvulsants, and does not listen to the main complaint of patients, and tends to use several drugs at the same time, which may cause confusion in treatment. 3. Choose drugs that take less frequently: Try to use antiepileptic drugs that are taken less frequently, especially those that are taken during the day are easily forgotten or inconvenient to take because of distress. It is better to use drugs taken at night. 4. Increase the dose of the controlled drug: Unless in status epilepticus or emergency treatment with very frequent seizures, generally a lower dose of the drug should be used at the beginning and slowly increased to the standard dose within a few weeks. If the seizures stop, do not increase the dose. If it still exists, continue to slowly increase the medication for several weeks or months until the seizure stops or side effects occur, or the dose has reached the limit. 5. It is appropriate to increase the dose of the drug: it is not necessary to increase the dose after each epileptic seizure, but long-term attention and consideration of its predisposing factors, such as mental stress, inability to continuously follow the doctor’s prescription, etc.
The normal range of platelet count is 100~300 (X10^9/L). When platelets exceed the normal range, thrombus will easily form, which is harmful to the human body. So the platelet count is more than 400, do I need treatment? The platelet count is more than 400, which has exceeded the normal count range. The patient needs to seek medical attention as soon as possible to find out the cause, and perform standard treatment after excluding other blood diseases. The platelet count is more than 400, how to treat it? There are many reasons for the increase of platelet count, such as infection, inflammation, trauma, etc. can also cause thrombocytosis. If this is the case, then the patient only needs to take symptomatic treatment during treatment. After the inflammation and infection are eliminated, and the wound is healed, it will usually recover on its own without special treatment. For patients who are diagnosed with essential thrombocythemia after excluding other blood diseases, they should receive standardized treatment as soon as possible. At present, clinical methods for treating essential thrombocythemia include hydroxyurea, interferon, anagrelide and traditional Chinese medicine, etc., which have good effects on the treatment of thrombocytosis. The specific method used varies from person to person. Need to combine the actual situation. Thrombocytosis not only has the risk of thrombosis, but also has a tendency to spontaneous bleeding. Therefore, in daily life, we must pay special attention to these two aspects. Especially in middle-aged and elderly people, thrombosis and bleeding tendency may shorten the survival time of patients. For more patient communication help, please pay attention to the WeChat public account [thrombocytosis patients association] xxbzd99
Polycythemia vera (PV) is a clonal chronic myeloproliferative disease of hematopoietic stem cells. PV starts insidiously and progresses slowly, and usually goes through the following two stages of progression: ① Proliferation or polycythemia phase-often with erythrocytosis; ② Late erythrocytosis-manifested as pancytopenia, extramedullary hematopoiesis, liver and spleen Large, hypersplenism and bone marrow fibrosis. The new drug for polycythemia vera, the two-year evaluation result of alfa-2b is “released”! What kind of medicine is this? This drug is a new single-isomer long-acting peginterferon in the clinical development stage for the treatment of patients with polycythemia vera (PV). Last year, in 2018, there was a 36-month progress result of this drug, which concluded that this drug has a good control effect and good tolerability. It makes medical practitioners more convinced that this drug will be a new generation of “interferon” (more knowledge comes from the bottom right of the picture). The beneficial result of this drug in the treatment of true red (the result of two-year evaluation) is released: • It can reflect better The advantages of available therapies; • Complete blood response rate and long-term clinical and blood response rate can be achieved; • Two-year safety and drug resistance are reflected; • The ability to relieve the disease has been further proved;… I hope that the popularization of new drugs can really benefit patients, so that every patient can see the onset of illness! Learn more about “disease knowledge” or “blood patient group communication” and other WeChat search public number: xejb120
Nowadays, the treatment of thrombocytosis in western medicine is mostly oral hydroxyurea and interferon. But we all know that the side effects of western medicine treatment are obvious. Patients treated with interferon reported that after the injection, they always felt muscle aches, fever, and dizziness. Therefore, many patients are very concerned, do I need to always inject interferon to treat this disease? Thrombocytosis is a disease of abnormal myeloproliferation, often manifested as a high platelet count in the peripheral blood. Because the cause of this disease is not clear and the condition is easy to recur, most patients need long-term or lifelong treatment to prevent the development of the disease and endanger the life of the patient. How to relieve the side effects of interferon? If the patient has side effects such as nausea and vomiting and poor sleep quality during the treatment, symptomatic treatment can be used to relieve it. In addition, patients can also add traditional Chinese medicine treatment to increase efficiency and reduce harm, relieve patients’ discomfort and symptoms, but also improve efficacy. Long-term injection of interferon has great side effects. If the patient has serious discomfort, he should actively communicate with the doctor to clarify the condition and determine whether it is necessary to change the medication or reduce the dosage to alleviate the impact of side effects. In addition to active treatment for patients with thrombocytosis, they should also pay attention to the prevention of bleeding tendency and thromboembolism in their daily life. These two symptoms are very dangerous for patients, especially middle-aged and elderly people. The formation of thrombosis will shorten the life of the patient or directly lead to it. The patient died. For more patient communication help, please pay attention to the WeChat public account [thrombocytosis patients association] xxbzd999
The treatment of thrombocytosis often uses hydroxyurea, interferon, aspirin and other drugs. Among them, interferon is mostly used in patients under the age of 40, so what should patients with thrombocytosis pay attention to when using interferon treatment Aspect? Beware of interferon side effects! How often do you check blood routines for thrombocytosis? ——Interferon is a cytokine, and some side effects will occur during the treatment. Note: The systemic reaction mainly manifests as flu-like symptoms, namely chills, fever, and discomfort; some patients with local reactions may have erythema and tenderness at the injection site ; Other hair loss, skin rash, rapid erythrocyte sedimentation rate, lethargy, liver damage. Occasionally anaphylactic shock. ——Interferon treatment of thrombocytosis, patients should check blood routine regularly: ① . Once a week in the first month of treatment; ② . Once every two weeks in the second month, and once a month thereafter; ③ . Once stabilized every 3 months. Some patients may have psychiatric symptoms such as hypothyroidism and depression after using interferon. Therefore, thyroid function tests should be performed before using interferon, and the patients should be carefully asked whether they have a history of mental illness. Thrombocytosis is a kind of abnormal proliferation of bone marrow. The disease progresses to the later stage and may develop in the direction of leukemia. Therefore, no matter which treatment method you choose, you must actively cooperate to control the condition as soon as possible and avoid the development of the disease. For more patient communication help, please pay attention to the WeChat public account [thrombocytosis patient association]xxbzd999
Acute leukemia is related to ion beams, some chemical drugs, genetic factors, retroviral infection, immune factors, etc. But most patients have difficulty finding a clear cause. In the usual preventive work, the following points should be paid attention to: ① Prevent and control radiation pollution. For example, families around radiation mines should pay attention to protection, and stone materials used for home decoration should pay attention to whether radiation exceeds the standard. Ionizing radiation is also one of the important causes. It is best for your residence to have a proper distance from high-voltage lines and high-power transmitters. ②The increasing incidence of acute leukemia in children may be related to the increasing pollution of drugs and toxicants. In the process of home decoration, environmentally friendly products should be used as much as possible to reduce the pollution of toxic chemicals in the residence, and pay attention before moving in. May be ventilated. ③Leukemia itself is not a hereditary disease, but some hereditary diseases have chromosomal abnormalities and thus genetic instability, so the incidence of leukemia increases, such as the incidence of leukemia with 21-trisomy syndrome, and the incidence of leukemia with identical twins, such as One person has leukemia, and the possibility of another sib’s leukemia is greatly increased. This should be taken seriously. ④Immune diseases. Cells in the human body often become cancerous. Why don’t most people suffer from tumors? Because there is an immune monitoring system in the body to remove these cancerous cells, if there are immune deficiencies, such as primary (ie congenital) immunodeficiency or acquired immunodeficiency such as AIDS, it is prone to leukemia or other tumors.
Thrombocytosis is mainly manifested by bleeding tendency and thrombosis. Western medicine is often treated with hydroxyurea, but the side effects of western medicine seriously reduce the patient’s quality of life. In addition to dizziness, there are symptoms such as nausea, vomiting, and black nails. So can TCM treat thrombocytosis? TCM treatment of thrombocytosis adopts syndrome differentiation treatment, and often pays attention to one person, which can effectively reduce thrombocytosis and its complications: patients with thrombocytosis belong to “blood syndrome”, “deficiency” and “accumulation” in the field of Chinese medicine, but the basic pathology is caused by “blood”. “Stasis” is caused, so it is sufficient to prove the cause of stasis due to wasting. Nowadays clinically in Chinese medicine, patients with thrombocytosis are mostly manifested as patients with Qi deficiency and blood stasis type, patients with Yin deficiency and blood stasis type, and patients with Qi Yin and blood stasis type. This type of patient’s disease is in the bone marrow, acquired loss of nourishment, blood is divided into yin, and proliferation is hyperactive. The patient’s yang is insufficient, and both qi and yin are deficient, causing stasis. Therefore, conditioning treatment should focus on replenishing yang and replenishing qi, while removing blood stasis and removing evil, and nourishing internal and external. The stasis caused by the fact is mostly patients with liver depression and blood stasis type. The patients are dry and disordered, blood stasis is not smooth, liver stagnation and qi, heat and toxins cause stasis. Such patients should be treated mainly by combing the liver and regulating qi, clearing away heat and detoxification, removing blood stasis, and removing dryness and warming. In addition, patients with thrombocythemia may also have other complications, such as thromboembolism, and TCM treatment can be appropriately adjusted according to the patient’s condition, and symptomatic administration. Although TCM treatment of thrombocytosis has slow results, the treatment is gentle and targeted, which improves the patient’s quality of life to a certain extent. In summary, targeted Chinese medicine is of great benefit to patients with primary thrombocytosis, provided that they need to seek medical treatment in a regular public hospital. For more patient communication help, please pay attention to the WeChat public account [thrombocytosis patient association]xxbzd999
Young and middle-aged patients with thrombocythemia have very different symptoms. The pathogenesis is mainly kidney deficiency and blood stasis, or combined with spleen deficiency, or liver weakness, which is always a syndrome of deficiency and deficiency, which is quite different from that of young thrombocythemia patients whose pathogenesis is mainly based on the standard and the actual. There are mainly two manifestations of symptoms in this regard. 【Spleen and Kidney Qi Deficiency】Cold and painful waist and knees, cold limbs, fatigue, abdominal distension, poor appetite, loose stools, frequent urination, pale tongue, white fur, and weak pulse; 【Liver and kidney deficiency】dizziness, dizziness, Sore waist and knees, body weight loss, numb limbs, five upset and hot, hot flashes and night sweats, dry skin, red tongue with little moss, even light red without moss, astringent pulse or broken number; the focus of Chinese medicine treatment for this- -It is advisable to both attack and replenish, taking into account the specimens, to replenish the kidney, liver and spleen. Whether it is Western medicine or TCM treatment of thrombocytosis, it is necessary to combine each patient’s own physical characteristics, while removing blood stasis, it also takes care of kidney, spleen, and liver, using specimens to strengthen the body and remove blood stasis, so that the righteousness will eliminate the evil ( No stasis) To learn more about “disease knowledge” or “blood patient group communication” and other WeChat search public number: xejb120